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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for TEAD3_TEAD1
Z-value: 4.35
Motif logo
Transcription factors associated with TEAD3_TEAD1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TEAD3
|
ENSG00000007866.14 | TEA domain transcription factor 3 |
|
TEAD1
|
ENSG00000187079.10 | TEA domain transcription factor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TEAD3 | hg19_v2_chr6_-_35464817_35464894 | 0.77 | 7.2e-05 | Click! |
| TEAD1 | hg19_v2_chr11_+_12696102_12696164 | 0.32 | 1.8e-01 | Click! |
Activity profile of TEAD3_TEAD1 motif
Sorted Z-values of TEAD3_TEAD1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of TEAD3_TEAD1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.6 | 13.8 | GO:0002605 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 2.3 | 6.8 | GO:1900085 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 2.0 | 5.9 | GO:2000646 | lipid transport involved in lipid storage(GO:0010877) positive regulation of receptor catabolic process(GO:2000646) |
| 1.4 | 28.8 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 1.4 | 4.1 | GO:0010160 | sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193) |
| 1.4 | 4.1 | GO:0042245 | RNA repair(GO:0042245) |
| 1.2 | 12.4 | GO:0090191 | negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) |
| 1.2 | 3.7 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
| 1.2 | 3.6 | GO:1904237 | regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) |
| 1.1 | 4.5 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 1.1 | 3.4 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
| 1.1 | 9.9 | GO:0097398 | response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398) |
| 1.1 | 3.3 | GO:0006738 | nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
| 1.1 | 4.2 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 1.0 | 4.2 | GO:0009956 | radial pattern formation(GO:0009956) |
| 1.0 | 4.1 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 1.0 | 8.9 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 1.0 | 17.7 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.9 | 34.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.9 | 17.5 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.9 | 5.2 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.8 | 5.7 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.8 | 3.9 | GO:0032796 | uropod organization(GO:0032796) |
| 0.8 | 3.8 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.7 | 7.9 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.7 | 2.1 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.7 | 4.7 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.7 | 3.4 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.7 | 9.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.6 | 4.5 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.6 | 3.8 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.6 | 3.7 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.6 | 12.1 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.6 | 4.7 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.6 | 2.9 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
| 0.6 | 1.7 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.6 | 1.7 | GO:0034059 | response to anoxia(GO:0034059) |
| 0.5 | 3.2 | GO:0072752 | cellular response to rapamycin(GO:0072752) |
| 0.5 | 13.1 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.5 | 9.0 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.5 | 1.5 | GO:2000705 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
| 0.5 | 1.0 | GO:0060532 | bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145) |
| 0.5 | 13.6 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.5 | 10.8 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.5 | 1.4 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.5 | 3.6 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.4 | 2.6 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.4 | 4.4 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.4 | 2.1 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.4 | 2.5 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
| 0.4 | 2.1 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.4 | 2.9 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
| 0.4 | 7.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.4 | 1.5 | GO:0008354 | germ cell migration(GO:0008354) |
| 0.4 | 2.6 | GO:1902962 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.4 | 2.2 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.3 | 8.4 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.3 | 1.0 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000) |
| 0.3 | 1.7 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.3 | 4.7 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.3 | 1.0 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 0.3 | 1.6 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.3 | 4.2 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.3 | 4.2 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.3 | 3.7 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.3 | 6.1 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.3 | 3.8 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.3 | 0.9 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 0.3 | 2.5 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.3 | 1.1 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.3 | 1.6 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.3 | 3.8 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.3 | 4.9 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 0.3 | 4.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.3 | 5.0 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.3 | 1.8 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.3 | 1.3 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569) |
| 0.3 | 18.1 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.3 | 1.0 | GO:1903860 | negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173) |
| 0.2 | 1.5 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.2 | 3.5 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.2 | 2.7 | GO:0070777 | gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.2 | 1.4 | GO:0072619 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.2 | 1.9 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.2 | 3.5 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.2 | 1.6 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.2 | 2.1 | GO:0030242 | pexophagy(GO:0030242) |
| 0.2 | 5.8 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.2 | 0.7 | GO:0040040 | thermosensory behavior(GO:0040040) |
| 0.2 | 1.3 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.2 | 3.1 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.2 | 1.5 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.2 | 1.1 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.2 | 3.2 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.2 | 3.8 | GO:0015816 | glycine transport(GO:0015816) |
| 0.2 | 2.3 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.2 | 1.0 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.2 | 1.0 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.2 | 1.2 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.2 | 1.4 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.2 | 32.2 | GO:0070268 | cornification(GO:0070268) |
| 0.2 | 1.2 | GO:0060161 | positive regulation of dopamine receptor signaling pathway(GO:0060161) |
| 0.2 | 1.2 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.2 | 2.4 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.2 | 1.2 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.2 | 1.3 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.2 | 9.5 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.2 | 1.5 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.2 | 1.3 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 0.2 | 0.5 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.2 | 0.9 | GO:0052250 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.2 | 0.7 | GO:0097045 | phosphatidylserine exposure on blood platelet(GO:0097045) |
| 0.2 | 0.8 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 0.2 | 2.0 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
| 0.2 | 1.2 | GO:0060449 | bud elongation involved in lung branching(GO:0060449) |
| 0.2 | 0.8 | GO:0042441 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.2 | 1.9 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.2 | 3.4 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.2 | 4.2 | GO:0098743 | cell aggregation(GO:0098743) |
| 0.2 | 5.3 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.2 | 2.9 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.2 | 2.1 | GO:0060346 | bone trabecula formation(GO:0060346) |
| 0.1 | 3.3 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.1 | 2.6 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.1 | 1.4 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 1.6 | GO:0035983 | response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984) |
| 0.1 | 2.1 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.1 | 0.3 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.1 | 1.2 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 6.3 | GO:0044247 | glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
| 0.1 | 6.6 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.1 | 1.3 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
| 0.1 | 0.5 | GO:0045208 | MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209) |
| 0.1 | 5.4 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.1 | 4.0 | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.1 | 1.3 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.1 | 2.9 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 0.9 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 0.1 | 0.6 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 2.7 | GO:0045652 | regulation of megakaryocyte differentiation(GO:0045652) |
| 0.1 | 0.3 | GO:0030070 | insulin processing(GO:0030070) |
| 0.1 | 3.1 | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166) |
| 0.1 | 1.3 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 2.1 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 2.7 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.1 | 1.9 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.4 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.1 | 1.7 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.1 | 1.2 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.1 | 0.6 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 0.2 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.1 | 0.6 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.1 | 0.3 | GO:0021816 | lamellipodium assembly involved in ameboidal cell migration(GO:0003363) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816) |
| 0.1 | 0.4 | GO:1903613 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.1 | 0.9 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.1 | 0.4 | GO:0010820 | positive regulation of T cell chemotaxis(GO:0010820) |
| 0.1 | 0.3 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.1 | 12.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.1 | 0.5 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.1 | 2.4 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
| 0.1 | 3.3 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 2.5 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.1 | 0.9 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 0.7 | GO:0070431 | nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431) |
| 0.1 | 0.4 | GO:0060686 | negative regulation of prostatic bud formation(GO:0060686) |
| 0.1 | 0.8 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.1 | 0.8 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 0.1 | 0.4 | GO:0021778 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.1 | 1.5 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.1 | 0.8 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.1 | 1.3 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.1 | 3.6 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.1 | 0.3 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.1 | 6.7 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.1 | 2.0 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.1 | 0.5 | GO:0060982 | coronary artery morphogenesis(GO:0060982) |
| 0.1 | 0.6 | GO:2000582 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.1 | 1.4 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.1 | 0.6 | GO:0010761 | fibroblast migration(GO:0010761) |
| 0.1 | 0.2 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 0.0 | 0.3 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
| 0.0 | 0.1 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
| 0.0 | 1.8 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.0 | 0.9 | GO:0042346 | positive regulation of NF-kappaB import into nucleus(GO:0042346) |
| 0.0 | 1.0 | GO:0035966 | response to unfolded protein(GO:0006986) response to topologically incorrect protein(GO:0035966) |
| 0.0 | 0.2 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.0 | 1.4 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 0.0 | 0.1 | GO:0046533 | negative regulation of photoreceptor cell differentiation(GO:0046533) |
| 0.0 | 0.4 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.0 | 1.0 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.0 | 0.2 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 0.0 | 2.4 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.0 | 0.3 | GO:0019556 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.0 | 1.6 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.3 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.0 | 2.6 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
| 0.0 | 1.8 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 1.0 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 1.8 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.0 | 0.9 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 10.0 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 0.1 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.0 | 1.5 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 1.4 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.0 | 5.0 | GO:0007163 | establishment or maintenance of cell polarity(GO:0007163) |
| 0.0 | 8.6 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.0 | 0.5 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.0 | 2.0 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
| 0.0 | 1.1 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.0 | 0.2 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.0 | 2.9 | GO:0021954 | central nervous system neuron development(GO:0021954) |
| 0.0 | 1.9 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.0 | 1.2 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.0 | 0.5 | GO:0060856 | establishment of blood-brain barrier(GO:0060856) |
| 0.0 | 1.6 | GO:0046785 | microtubule polymerization(GO:0046785) |
| 0.0 | 0.2 | GO:0002729 | positive regulation of natural killer cell cytokine production(GO:0002729) |
| 0.0 | 1.7 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.0 | 3.8 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 1.2 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 4.3 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.0 | 0.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 4.0 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.1 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.0 | 1.4 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
| 0.0 | 0.6 | GO:0000271 | polysaccharide biosynthetic process(GO:0000271) |
| 0.0 | 0.2 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 0.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.1 | GO:0006528 | asparagine metabolic process(GO:0006528) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.3 | 17.4 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 2.0 | 5.9 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.9 | 13.8 | GO:0030478 | actin cap(GO:0030478) |
| 0.9 | 3.4 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.8 | 2.5 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.7 | 4.3 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.7 | 4.2 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.7 | 3.4 | GO:0035838 | growing cell tip(GO:0035838) |
| 0.6 | 9.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.6 | 10.8 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.5 | 2.1 | GO:0034271 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.5 | 1.5 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
| 0.5 | 8.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.4 | 3.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.4 | 10.8 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.4 | 12.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.4 | 4.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.4 | 5.2 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.4 | 2.5 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.3 | 3.8 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.3 | 2.0 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.3 | 1.6 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.3 | 4.1 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.3 | 4.5 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.3 | 14.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.3 | 8.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 3.8 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.2 | 6.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 1.2 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.2 | 3.6 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.2 | 3.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.2 | 1.9 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.2 | 1.6 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.2 | 0.5 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 1.2 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
| 0.2 | 1.3 | GO:0070695 | FHF complex(GO:0070695) |
| 0.2 | 1.4 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.2 | 0.5 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.1 | 24.2 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 5.2 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 0.3 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
| 0.1 | 1.5 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.1 | 13.8 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 3.3 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.1 | 3.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 6.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 9.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 0.8 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 0.1 | 5.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 2.4 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 3.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 1.5 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 2.3 | GO:0036477 | somatodendritic compartment(GO:0036477) |
| 0.1 | 1.7 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 1.2 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.1 | 1.2 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 0.2 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 0.1 | 6.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 31.2 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 1.2 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 2.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 7.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 1.9 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.1 | 0.8 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.1 | 3.6 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 3.9 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.1 | 5.2 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 11.2 | GO:0030018 | Z disc(GO:0030018) |
| 0.1 | 1.5 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 3.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 3.5 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 5.9 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 4.9 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 4.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 5.2 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 16.7 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.1 | GO:0030055 | cell-substrate junction(GO:0030055) |
| 0.0 | 4.7 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 0.2 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.0 | 6.3 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.5 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.0 | 0.5 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.0 | 1.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 4.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.6 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.8 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.2 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.1 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.0 | 2.7 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 0.6 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 1.9 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.0 | 0.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 1.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 3.9 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 35.0 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 2.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.7 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
| 0.0 | 2.5 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.8 | GO:0000786 | nucleosome(GO:0000786) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 13.8 | GO:0070052 | collagen V binding(GO:0070052) |
| 2.3 | 6.8 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 1.5 | 5.9 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 1.3 | 6.6 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 1.2 | 3.6 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
| 1.2 | 17.5 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 1.1 | 3.3 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 1.1 | 2.2 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 1.1 | 13.1 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 1.0 | 10.4 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 1.0 | 14.4 | GO:0038132 | neuregulin binding(GO:0038132) |
| 1.0 | 4.1 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 1.0 | 4.1 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.8 | 3.4 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.6 | 5.2 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.6 | 4.0 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.5 | 4.3 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.5 | 5.4 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.4 | 5.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.4 | 1.3 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.4 | 10.3 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.4 | 2.6 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.4 | 1.1 | GO:0019981 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) |
| 0.4 | 10.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.4 | 13.9 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.3 | 8.4 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.3 | 1.9 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.3 | 1.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.3 | 3.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.3 | 1.9 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.3 | 2.7 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.3 | 2.9 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.3 | 1.3 | GO:0005462 | UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) |
| 0.3 | 7.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.3 | 10.5 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.3 | 3.3 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.3 | 3.8 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.3 | 6.1 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.3 | 3.1 | GO:0036122 | BMP binding(GO:0036122) |
| 0.2 | 1.0 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.2 | 1.7 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.2 | 5.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.2 | 2.5 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.2 | 2.1 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.2 | 1.3 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.2 | 2.2 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.2 | 0.8 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.2 | 1.8 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.2 | 7.7 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 1.4 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.2 | 4.0 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.2 | 1.0 | GO:0010736 | serum response element binding(GO:0010736) |
| 0.2 | 2.1 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.2 | 1.2 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.2 | 1.9 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.2 | 3.0 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 5.8 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 1.2 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.2 | 0.9 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.2 | 21.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.2 | 1.2 | GO:0043532 | angiostatin binding(GO:0043532) |
| 0.2 | 14.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.2 | 2.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.2 | 7.7 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.2 | 3.6 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.2 | 2.5 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.2 | 3.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.2 | 0.8 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.1 | 1.0 | GO:0070728 | leucine binding(GO:0070728) |
| 0.1 | 3.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 3.3 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 5.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 10.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 4.9 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 4.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.9 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
| 0.1 | 2.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 3.4 | GO:0015464 | acetylcholine receptor activity(GO:0015464) |
| 0.1 | 3.8 | GO:0032041 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 2.0 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.1 | 4.2 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 5.2 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.1 | 0.6 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 2.8 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 0.5 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.1 | 1.5 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 13.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.4 | GO:0051120 | hepoxilin A3 synthase activity(GO:0051120) |
| 0.1 | 1.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.1 | 4.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 2.7 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 1.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 2.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.1 | 3.8 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 1.6 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 22.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 0.8 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.1 | 0.2 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.1 | 1.7 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 13.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 0.8 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 2.4 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 3.8 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.1 | 2.8 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 1.5 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.1 | 2.0 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.1 | 3.6 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.1 | 3.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.9 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 9.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 8.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 1.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.1 | 1.3 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
| 0.1 | 9.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 1.4 | GO:0016887 | ATPase activity(GO:0016887) |
| 0.1 | 0.9 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.0 | 0.1 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
| 0.0 | 2.3 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 1.1 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.7 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 5.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 8.3 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 2.2 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 1.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 4.5 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.1 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.0 | 0.1 | GO:0050146 | nucleoside phosphotransferase activity(GO:0050146) |
| 0.0 | 0.3 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 0.0 | 0.7 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 1.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.6 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 1.3 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 1.1 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.0 | 0.3 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.5 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.0 | 0.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 1.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 4.2 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.7 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0004556 | alpha-amylase activity(GO:0004556) amylase activity(GO:0016160) |
| 0.0 | 2.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.3 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 0.8 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.4 | GO:0008381 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.0 | 0.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.0 | 0.2 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.0 | 0.4 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 0.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.0 | 3.6 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.8 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 1.1 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.0 | 0.4 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.0 | 2.5 | GO:0051213 | dioxygenase activity(GO:0051213) |
| 0.0 | 1.7 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 6.9 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.4 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
| 0.0 | 2.1 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 1.3 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.5 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.0 | 0.1 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 4.4 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.1 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 34.6 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.4 | 25.0 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.4 | 28.5 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.2 | 8.9 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 4.7 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 9.3 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 6.1 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 8.2 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 2.1 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.1 | 1.3 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.1 | 4.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 4.9 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 8.1 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 9.5 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 10.1 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 2.8 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 1.5 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 5.0 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 5.7 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 6.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 2.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 3.3 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 2.1 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 4.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 4.6 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.1 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 2.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 2.3 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.9 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 4.2 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.7 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 2.8 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 6.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.1 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.5 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.5 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 1.6 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.5 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 9.6 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.2 | 5.5 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.2 | 11.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 6.8 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.2 | 4.5 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.2 | 6.1 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.2 | 8.5 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.2 | 3.8 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.2 | 6.6 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 2.9 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 4.6 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.6 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 4.2 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.1 | 5.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 3.3 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 19.9 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 5.8 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 9.6 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 1.2 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.1 | 1.8 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 2.8 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 1.2 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.1 | 2.5 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 5.6 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 2.7 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 11.4 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 18.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 1.6 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.1 | 2.1 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 3.1 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 2.9 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 2.3 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 0.9 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 0.3 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 2.5 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 5.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 1.5 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 1.2 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 2.3 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 1.7 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 4.3 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.9 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 1.1 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 2.4 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 3.4 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 0.9 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 1.3 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 1.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 1.8 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.1 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 2.1 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.6 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.1 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.2 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 1.2 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |