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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFCP2

Z-value: 1.35

Motif logo

Transcription factors associated with TFCP2

Gene Symbol Gene ID Gene Info
ENSG00000135457.5 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2hg19_v2_chr12_-_51566592_515666950.802.7e-05Click!

Activity profile of TFCP2 motif

Sorted Z-values of TFCP2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.4 4.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 1.6 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.4 1.4 GO:1990502 dense core granule maturation(GO:1990502)
0.3 1.0 GO:1903542 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.2 1.0 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 2.0 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.2 1.0 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 1.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.2 0.9 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.2 0.9 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 0.6 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 0.6 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.8 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.9 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.6 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.4 GO:0044209 AMP salvage(GO:0044209)
0.1 0.9 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.4 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 1.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.8 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 1.6 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.0 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 1.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.3 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 1.3 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.6 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.9 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.2 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.5 GO:0030421 defecation(GO:0030421)
0.1 0.8 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 0.5 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.1 1.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.3 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.6 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.3 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.3 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.4 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.3 GO:1901029 adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 1.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.3 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.6 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) lipid glycosylation(GO:0030259)
0.0 1.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 1.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.4 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0015871 choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.5 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.5 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.4 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 1.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.6 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 1.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.5 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.8 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.6 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 1.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0009642 response to light intensity(GO:0009642)
0.0 1.6 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 1.9 GO:0031415 NatA complex(GO:0031415)
0.2 0.7 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 1.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0001534 radial spoke(GO:0001534)
0.1 0.9 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 1.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.0 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.9 GO:0000124 SAGA complex(GO:0000124)
0.1 2.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.2 GO:0005715 late recombination nodule(GO:0005715)
0.1 1.0 GO:0031298 replication fork protection complex(GO:0031298)
0.1 1.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.3 GO:0019867 outer membrane(GO:0019867)
0.1 1.0 GO:0090543 Flemming body(GO:0090543)
0.1 1.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 3.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.6 GO:0071565 SWI/SNF complex(GO:0016514) nBAF complex(GO:0071565)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 2.3 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.6 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.7 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 0.9 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.2 4.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.8 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 0.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.6 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 3.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.1 2.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 2.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1 0.9 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 0.4 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.3 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.2 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 1.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.0 2.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 2.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.8 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 2.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.4 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.2 PID AURORA B PATHWAY Aurora B signaling
0.0 2.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.3 REACTOME KINESINS Genes involved in Kinesins
0.1 2.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.7 REACTOME NEUROTRANSMITTER RELEASE CYCLE Genes involved in Neurotransmitter Release Cycle
0.0 2.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling