avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
THRB Links Ensembl NCBI GeneCards UniProt	ENSG00000151090.13	thyroid hormone receptor beta

Gene	Promoter	Pearson corr. coef.	P-value	Plot
THRB	hg19_v2_chr3_-_24536222_24536249	-0.85	2.4e-06	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.1	GO:0002432	granuloma formation(GO:0002432)
0.4	2.5	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
0.3	1.0	GO:0006173	dADP biosynthetic process(GO:0006173)
0.3	1.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.2	0.7	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2	1.7	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.1	0.7	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.1	2.0	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.5	GO:1990167	protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1	0.7	GO:2000568	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1	0.4	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.5	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.3	GO:0036371	protein localization to T-tubule(GO:0036371)
0.0	1.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	1.0	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.4	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	1.4	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.4	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	2.3	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	1.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.6	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.5	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.3	1.7	GO:0071797	LUBAC complex(GO:0071797)
0.2	4.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.2	2.0	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.4	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.0	0.5	GO:0005577	fibrinogen complex(GO:0005577)
0.0	1.2	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.2	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
0.1	0.5	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1	0.7	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1	1.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	2.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	1.4	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1	0.6	GO:0005497	androgen binding(GO:0005497)
0.1	0.7	GO:0051525	NFAT protein binding(GO:0051525)
0.0	1.0	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	1.0	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.6	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	2.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	4.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.4	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.0	GO:0001515	opioid peptide activity(GO:0001515)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.5	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	1.1	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	1.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport