avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
TLX2 Links Ensembl NCBI GeneCards UniProt	ENSG00000115297.9	T cell leukemia homeobox 2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TLX2	hg19_v2_chr2_+_74741569_74741620	-0.72	3.8e-04	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	7.5	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.4	6.8	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.3	3.9	GO:0042938	dipeptide transport(GO:0042938)
1.2	5.9	GO:0003165	Purkinje myocyte development(GO:0003165)
1.1	5.4	GO:1903282	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
1.0	3.1	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
1.0	2.9	GO:0002644	negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.9	2.6	GO:0019858	cytosine metabolic process(GO:0019858)
0.9	3.5	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.9	4.3	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
0.9	12.2	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.9	3.4	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.7	2.8	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.7	3.5	GO:0048496	adherens junction maintenance(GO:0034334) maintenance of organ identity(GO:0048496)
0.7	6.1	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.6	1.9	GO:0006117	acetaldehyde metabolic process(GO:0006117)
0.6	2.3	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.5	3.8	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.5	4.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.5	5.3	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.5	5.7	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.4	6.7	GO:0032119	sequestering of zinc ion(GO:0032119)
0.4	3.5	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.4	1.6	GO:0018277	protein deamination(GO:0018277)
0.4	1.2	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.4	2.4	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.4	1.2	GO:0002661	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.4	2.4	GO:1902045	negative regulation of Fas signaling pathway(GO:1902045)
0.4	4.2	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4	7.0	GO:0090179	planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.4	2.5	GO:2000537	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.4	2.5	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.4	1.4	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.4	2.5	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3	8.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3	3.7	GO:2000580	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3	2.4	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.3	0.9	GO:0021589	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3	3.4	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.3	0.8	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.3	1.4	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.3	0.5	GO:0032765	positive regulation of mast cell cytokine production(GO:0032765)
0.3	3.5	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3	1.6	GO:0010193	response to ozone(GO:0010193)
0.3	0.8	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.3	1.3	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2	4.7	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.2	3.4	GO:0015705	iodide transport(GO:0015705)
0.2	1.2	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.2	2.1	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2	1.6	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.2	2.7	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2	2.5	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.2	2.6	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.2	0.9	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.2	0.6	GO:0007231	osmosensory signaling pathway(GO:0007231)
0.2	0.6	GO:0001543	ovarian follicle rupture(GO:0001543)
0.2	3.2	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2	1.5	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.2	0.8	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.2	1.4	GO:1902164	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2	0.6	GO:0061386	closure of optic fissure(GO:0061386)
0.2	1.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.2	1.0	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.2	0.8	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2	0.9	GO:2000691	regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2	1.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2	1.6	GO:0060174	limb bud formation(GO:0060174)
0.2	0.9	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2	0.9	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.2	1.7	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.2	0.9	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2	0.5	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
0.2	6.0	GO:0033622	integrin activation(GO:0033622)
0.2	0.2	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747) positive regulation of protein lipidation(GO:1903061)
0.2	1.1	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2	7.7	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.2	0.5	GO:0031247	actin rod assembly(GO:0031247)
0.1	1.8	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	0.7	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1	3.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	1.6	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	1.0	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1	2.2	GO:0002934	desmosome organization(GO:0002934)
0.1	1.8	GO:0006477	protein sulfation(GO:0006477)
0.1	0.4	GO:0015880	coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1	1.7	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	1.6	GO:1902570	protein localization to nucleolus(GO:1902570)
0.1	1.9	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	1.2	GO:0034350	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1	1.3	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	0.4	GO:1903060	regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.1	0.2	GO:2000981	negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1	0.2	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1	0.6	GO:0030573	bile acid catabolic process(GO:0030573)
0.1	0.7	GO:0015722	canalicular bile acid transport(GO:0015722)
0.1	4.1	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1	1.9	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1	2.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	5.4	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.1	0.8	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	1.2	GO:0032202	telomere assembly(GO:0032202)
0.1	0.7	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1	2.7	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	1.2	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.7	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	1.4	GO:0015871	choline transport(GO:0015871)
0.1	2.4	GO:0051531	NFAT protein import into nucleus(GO:0051531)
0.1	3.6	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1	1.7	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	2.7	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.1	0.5	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1	1.3	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.1	6.3	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.1	0.7	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	2.2	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.9	GO:0010593	negative regulation of lamellipodium assembly(GO:0010593)
0.1	2.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.5	GO:0060161	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1	2.0	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	0.2	GO:0019254	amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.1	0.3	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
0.1	0.7	GO:0032887	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1	1.3	GO:0002643	regulation of tolerance induction(GO:0002643)
0.1	1.0	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.1	1.0	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.1	0.2	GO:0070781	arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1	0.7	GO:0032482	Rab protein signal transduction(GO:0032482)
0.1	1.0	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.2	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.1	0.6	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.1	0.6	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	1.2	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	1.7	GO:0042481	regulation of odontogenesis(GO:0042481)
0.1	4.1	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.6	GO:0003344	pericardium morphogenesis(GO:0003344)
0.1	1.2	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.1	5.4	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.1	0.7	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.6	GO:0034398	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1	5.5	GO:0042795	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1	0.2	GO:0035995	detection of muscle stretch(GO:0035995)
0.1	0.7	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	1.8	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.1	0.2	GO:0031081	nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.0	4.2	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.4	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.2	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.8	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	1.5	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	1.0	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.8	GO:0060056	mammary gland involution(GO:0060056)
0.0	1.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	1.8	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.2	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.7	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.0	1.0	GO:0030183	B cell differentiation(GO:0030183)
0.0	1.6	GO:0042554	superoxide anion generation(GO:0042554)
0.0	0.2	GO:1902896	terminal web assembly(GO:1902896)
0.0	0.2	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.5	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	2.9	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	3.9	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0	1.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.5	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	2.9	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	1.0	GO:0001701	in utero embryonic development(GO:0001701)
0.0	0.3	GO:0051451	myoblast migration(GO:0051451)
0.0	0.8	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.8	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.2	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.7	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.9	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.7	GO:0032376	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.4	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	1.3	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.1	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.3	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	1.2	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.8	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	3.7	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	4.0	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.7	GO:0071732	cellular response to nitric oxide(GO:0071732)
0.0	1.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.1	GO:0032431	positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0	0.4	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	1.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.7	GO:0046174	polyol catabolic process(GO:0046174)
0.0	0.2	GO:0046464	neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0	1.1	GO:0018149	peptide cross-linking(GO:0018149)
0.0	1.9	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.7	GO:0003351	epithelial cilium movement(GO:0003351)
0.0	0.1	GO:0010446	response to alkaline pH(GO:0010446) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.7	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.3	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	3.2	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071)
0.0	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.0	1.8	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.3	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.1	GO:2000510	positive regulation of sperm motility involved in capacitation(GO:0060474) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	2.4	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	1.9	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.3	GO:0001955	blood vessel maturation(GO:0001955)
0.0	1.3	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
0.0	0.7	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.0	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.5	GO:0030855	epithelial cell differentiation(GO:0030855)
0.0	0.5	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	3.8	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	1.3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.7	GO:0035196	production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0	0.5	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.2	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0	0.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	1.3	GO:0007032	endosome organization(GO:0007032)
0.0	1.9	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.2	GO:0015824	proline transport(GO:0015824)
0.0	0.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.6	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.3	GO:0043086	negative regulation of catalytic activity(GO:0043086)
0.0	0.2	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.3	GO:0014898	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0	0.0	GO:0061056	sclerotome development(GO:0061056)
0.0	0.5	GO:0017144	drug metabolic process(GO:0017144)
0.0	1.3	GO:0045727	positive regulation of translation(GO:0045727)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0045617	negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of keratinocyte differentiation(GO:0045617)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.6	GO:0070876	SOSS complex(GO:0070876)
0.6	3.2	GO:1990425	ryanodine receptor complex(GO:1990425)
0.6	1.9	GO:0035525	NF-kappaB p50/p65 complex(GO:0035525)
0.4	5.4	GO:0061689	tricellular tight junction(GO:0061689)
0.4	2.4	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4	1.1	GO:0034515	proteasome storage granule(GO:0034515)
0.3	3.5	GO:0005593	FACIT collagen trimer(GO:0005593)
0.3	2.5	GO:0016013	syntrophin complex(GO:0016013)
0.3	1.1	GO:1990745	EARP complex(GO:1990745)
0.3	2.4	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.3	2.1	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	0.8	GO:0005668	RNA polymerase transcription factor SL1 complex(GO:0005668)
0.2	2.5	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.2	18.3	GO:0001533	cornified envelope(GO:0001533)
0.2	0.7	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2	6.1	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.2	1.3	GO:0031673	H zone(GO:0031673)
0.2	0.9	GO:0097232	lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2	1.8	GO:0032010	phagolysosome(GO:0032010)
0.2	1.1	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.2	2.0	GO:0000439	core TFIIH complex(GO:0000439)
0.2	4.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	1.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.2	6.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	2.2	GO:0030057	desmosome(GO:0030057)
0.2	0.5	GO:1990015	mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.2	6.8	GO:0097228	sperm principal piece(GO:0097228)
0.1	7.6	GO:0009925	basal plasma membrane(GO:0009925)
0.1	5.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	1.8	GO:0042587	glycogen granule(GO:0042587)
0.1	0.9	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	1.4	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1	3.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.5	GO:0032449	CBM complex(GO:0032449)
0.1	1.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.7	GO:0035061	interchromatin granule(GO:0035061)
0.1	2.5	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	8.2	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1	1.0	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1	0.7	GO:0031415	NatA complex(GO:0031415)
0.1	3.5	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.4	GO:0005846	nuclear cap binding complex(GO:0005846)
0.1	2.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	12.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	2.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.7	GO:0055028	cortical microtubule(GO:0055028)
0.1	1.0	GO:0031105	septin complex(GO:0031105)
0.1	0.7	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	2.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.3	GO:0014802	terminal cisterna(GO:0014802)
0.1	1.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	3.1	GO:0005605	basal lamina(GO:0005605)
0.1	1.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	0.6	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.9	GO:0005740	mitochondrial envelope(GO:0005740)
0.1	1.1	GO:0032433	filopodium tip(GO:0032433)
0.1	0.7	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	1.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	1.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.8	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.4	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	1.5	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.2	GO:0071942	XPC complex(GO:0071942)
0.0	2.0	GO:0034451	centriolar satellite(GO:0034451)
0.0	3.5	GO:0016235	aggresome(GO:0016235)
0.0	1.0	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	2.6	GO:0005771	multivesicular body(GO:0005771)
0.0	2.3	GO:0002102	podosome(GO:0002102)
0.0	0.5	GO:0034709	methylosome(GO:0034709)
0.0	1.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:1990357	terminal web(GO:1990357)
0.0	0.7	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.7	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.2	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	3.1	GO:0005604	basement membrane(GO:0005604)
0.0	3.7	GO:0005643	nuclear pore(GO:0005643)
0.0	1.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	2.0	GO:0005871	kinesin complex(GO:0005871)
0.0	12.1	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.6	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	2.3	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	1.2	GO:0097542	ciliary tip(GO:0097542)
0.0	1.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	2.3	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	12.6	GO:0045177	apical part of cell(GO:0045177)
0.0	0.5	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.4	GO:0035371	microtubule plus-end(GO:0035371)
0.0	4.5	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	2.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	2.9	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	1.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	5.1	GO:0001726	ruffle(GO:0001726)
0.0	1.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0044306	neuron projection terminus(GO:0044306)
0.0	1.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.5	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	1.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.6	GO:0030027	lamellipodium(GO:0030027)
0.0	1.1	GO:0005903	brush border(GO:0005903)
0.0	0.6	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	4.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.7	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	1.0	GO:0045171	intercellular bridge(GO:0045171)
0.0	1.0	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0061695	transferase complex, transferring phosphorus-containing groups(GO:0061695)
0.0	0.2	GO:0070187	telosome(GO:0070187)
0.0	0.8	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	2.6	GO:0001650	fibrillar center(GO:0001650)
0.0	0.3	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	1.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.7	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.0	0.5	GO:0030529	intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0	0.7	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	14.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
1.4	4.3	GO:0016964	alpha-2 macroglobulin receptor activity(GO:0016964)
1.3	3.8	GO:0002113	interleukin-33 binding(GO:0002113)
1.1	5.4	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.8	9.4	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.7	6.4	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.6	15.6	GO:0045499	chemorepellent activity(GO:0045499)
0.5	2.7	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5	3.9	GO:0004064	arylesterase activity(GO:0004064)
0.5	6.8	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.4	2.5	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4	14.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.4	5.5	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4	2.6	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4	1.8	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3	3.4	GO:0071532	ankyrin repeat binding(GO:0071532)
0.3	2.1	GO:0004522	ribonuclease A activity(GO:0004522)
0.3	1.2	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.3	5.3	GO:0008199	ferric iron binding(GO:0008199)
0.3	4.4	GO:0008097	5S rRNA binding(GO:0008097)
0.3	0.8	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.3	1.4	GO:0052839	inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.3	2.4	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.3	3.6	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3	1.8	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.2	9.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	1.7	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.2	0.7	GO:0070538	oleic acid binding(GO:0070538)
0.2	0.9	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.2	3.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.2	0.7	GO:0015432	bile acid-exporting ATPase activity(GO:0015432)
0.2	0.9	GO:0052642	lysophosphatidic acid phosphatase activity(GO:0052642)
0.2	0.6	GO:0030366	molybdopterin synthase activity(GO:0030366)
0.2	0.6	GO:0050146	nucleoside phosphotransferase activity(GO:0050146)
0.2	3.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.2	1.0	GO:0004556	alpha-amylase activity(GO:0004556)
0.2	4.7	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2	3.5	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.2	3.2	GO:0019855	calcium channel inhibitor activity(GO:0019855) type I transforming growth factor beta receptor binding(GO:0034713)
0.2	4.6	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2	1.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.2	2.4	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.2	1.9	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2	2.9	GO:0032395	MHC class II receptor activity(GO:0032395)
0.2	1.0	GO:0004096	catalase activity(GO:0004096)
0.2	3.7	GO:0045504	dynein heavy chain binding(GO:0045504)
0.2	1.4	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.2	1.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.2	2.5	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.2	0.6	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1	1.6	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	1.6	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.4	GO:0015228	coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1	0.9	GO:0051022	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	5.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	7.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	4.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	3.2	GO:0031005	filamin binding(GO:0031005)
0.1	1.8	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.3	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.1	2.5	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	3.7	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	5.0	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.1	6.9	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.8	GO:0052723	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1	6.2	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.8	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	1.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	0.4	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.1	0.6	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.2	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	1.7	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	1.6	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	1.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	0.7	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1	1.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.3	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.7	GO:0008172	S-methyltransferase activity(GO:0008172)
0.1	1.0	GO:0030274	LIM domain binding(GO:0030274)
0.1	1.5	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	1.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	1.5	GO:0032052	bile acid binding(GO:0032052)
0.1	1.6	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.5	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1	0.2	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.1	0.8	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.7	GO:0048495	Roundabout binding(GO:0048495)
0.1	3.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	1.6	GO:0031432	titin binding(GO:0031432)
0.1	2.6	GO:0001848	complement binding(GO:0001848)
0.1	0.2	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.1	0.7	GO:0019864	IgG binding(GO:0019864)
0.1	3.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	5.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.6	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.1	1.6	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.8	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.2	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.1	2.4	GO:0005123	death receptor binding(GO:0005123)
0.1	1.6	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1	1.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	2.0	GO:0008143	poly(A) binding(GO:0008143)
0.1	0.5	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	1.7	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	2.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	6.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.4	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	1.8	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	1.0	GO:0008432	JUN kinase binding(GO:0008432)
0.0	2.0	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	1.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	8.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.9	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.0	0.9	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.5	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	3.5	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.2	GO:0031433	telethonin binding(GO:0031433)
0.0	1.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0098782	mechanically-gated potassium channel activity(GO:0098782)
0.0	0.6	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	4.6	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.9	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.6	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	1.8	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.4	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.5	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.3	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	8.6	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.8	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.4	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	1.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	1.6	GO:0019003	GDP binding(GO:0019003)
0.0	1.8	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	1.7	GO:0001618	virus receptor activity(GO:0001618)
0.0	1.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	1.0	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0	0.6	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	1.2	GO:0002039	p53 binding(GO:0002039)
0.0	0.6	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.7	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.4	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.3	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	14.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	13.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	1.7	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	4.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	6.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	23.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	2.9	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	4.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	8.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	6.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	5.7	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	4.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	1.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	2.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.7	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	3.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.1	4.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	3.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	0.9	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	3.7	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	2.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	2.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	3.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	5.8	PID NOTCH PATHWAY	Notch signaling pathway
0.0	2.0	PID ARF6 PATHWAY	Arf6 signaling events
0.0	1.9	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	1.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	4.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	3.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	2.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	3.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	2.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	2.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.4	PID ENDOTHELIN PATHWAY	Endothelins
0.0	1.1	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.4	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	1.8	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	2.6	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.2	2.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	4.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	2.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.9	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	5.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	1.7	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	3.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	4.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	2.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	4.7	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	1.3	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	6.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	6.4	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	1.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.8	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	3.8	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.1	3.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	3.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.0	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	2.8	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.1	5.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	2.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.3	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	3.1	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	2.5	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	4.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	1.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	1.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	1.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	2.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	3.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.7	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	3.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	2.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	4.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.4	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.1	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	1.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.5	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.2	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
0.0	0.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.4	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	1.4	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins