ISMARA results: TP73

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TP73

Z-value: 2.01

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Transcription factors associated with TP73

Gene Symbol	Gene ID	Gene Info
TP73 Ensembl NCBI GeneCards UniProt	ENSG00000078900.10	tumor protein p73

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TP73	hg19_v2_chr1_+_3598871_3598930	0.23	3.3e-01	Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

No targets for TP73

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	10.7	GO:0001661	conditioned taste aversion(GO:0001661)
0.3	8.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
1.9	7.7	GO:0001808	negative regulation of type IV hypersensitivity(GO:0001808)
1.2	4.9	GO:2001287	negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1	2.7	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4	2.1	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1	2.1	GO:0035878	nail development(GO:0035878)
0.0	2.1	GO:0048477	oogenesis(GO:0048477)
0.2	2.0	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	1.8	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)

Showing 1 to 10 of 46 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	10.7	GO:0035976	AP1 complex(GO:0035976)
1.0	4.9	GO:0044393	microspike(GO:0044393)
0.7	2.1	GO:0036117	hyaluranon cable(GO:0036117)
0.0	2.0	GO:0030057	desmosome(GO:0030057)
0.1	1.9	GO:0030056	hemidesmosome(GO:0030056)
0.0	1.6	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	1.4	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	1.4	GO:0032590	dendrite membrane(GO:0032590)
0.1	1.3	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	1.2	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Showing 1 to 10 of 19 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	10.8	GO:0070412	R-SMAD binding(GO:0070412)
0.1	8.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
1.3	7.7	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	4.9	GO:0015485	cholesterol binding(GO:0015485)
0.0	2.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	2.5	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	2.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.4	2.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	2.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	2.1	GO:0005496	steroid binding(GO:0005496)

Showing 1 to 10 of 38 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	10.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	4.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	2.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.4	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes

Showing 1 to 7 of 7 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	10.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	2.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	1.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis

Showing 1 to 10 of 16 entries

Results for TP73

Z-value: 2.01

Motif logo

Transcription factors associated with TP73

Activity-expression correlation:

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

No targets for TP73

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: