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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for UAGUGUU
Z-value: 1.50
Activity profile of UAGUGUU motif
Mock_treat...AV_control
IAV_infected_A549_cells
SARS-CoV-2_infected_A549_cells
Mock_treat...C2_control
SARS-CoV-2_infected_NHBE_cells
Mock_treated_NHBE_cells
Mock_treat...SV_control
RSV_infected_A549_cells
−0.1
−0.08
−0.06
−0.04
−0.02
0
0.02
0.04
0.06
activity (log2(tpm) per TFBS)
plotly-logomark
Sorted Z-values of UAGUGUU motif
−3
−2.5
−2
−1.5
−1
−0.5
0
0.5
1
1.5
RSV_infected_A549_cells
Mock_treat...SV_control
Mock_treat...C2_control
SARS-CoV-2_infected_A549_cells
Mock_treat...AV_control
SARS-CoV-2_infected_NHBE_cells
Mock_treated_NHBE_cells
IAV_infected_A549_cells
Z-value
plotly-logomark
No targets for UAGUGUU
Network of associatons between targets according to the
STRING database.
First level regulatory network of UAGUGUU
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Gene Ontology Analysis
Gene overrepresentation in biological_process category:
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Log-likelihood per target
Total log-likelihood
Term
Description
0.7
2.8
GO:1903984
positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0
2.4
GO:0045022
early endosome to late endosome transport(GO:0045022)
0.3
2.3
GO:0030579
ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0
1.9
GO:0006368
transcription elongation from RNA polymerase II promoter(GO:0006368)
0.2
1.4
GO:0070164
negative regulation of adiponectin secretion(GO:0070164)
0.1
1.4
GO:1900086
positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1
1.4
GO:0010839
negative regulation of keratinocyte proliferation(GO:0010839)
0.4
1.3
GO:0031106
septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.1
1.3
GO:0002329
pre-B cell differentiation(GO:0002329)
0.3
1.2
GO:0061763
multivesicular body-lysosome fusion(GO:0061763)
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Gene overrepresentation in cellular_component category:
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Log-likelihood per target
Total log-likelihood
Term
Description
0.2
2.8
GO:0031089
platelet dense granule lumen(GO:0031089)
0.0
2.3
GO:0055038
recycling endosome membrane(GO:0055038)
0.4
2.2
GO:0044308
axonal spine(GO:0044308)
0.0
2.0
GO:0030175
filopodium(GO:0030175)
0.0
1.6
GO:0005876
spindle microtubule(GO:0005876)
0.1
1.4
GO:0036057
filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0
1.4
GO:0030670
phagocytic vesicle membrane(GO:0030670)
0.2
1.3
GO:0005826
actomyosin contractile ring(GO:0005826)
0.1
1.3
GO:0035253
ciliary rootlet(GO:0035253)
0.1
1.2
GO:0000815
ESCRT III complex(GO:0000815)
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Gene overrepresentation in molecular_function category:
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Log-likelihood per target
Total log-likelihood
Term
Description
0.1
3.2
GO:0005545
1-phosphatidylinositol binding(GO:0005545)
0.1
2.8
GO:0008191
metalloendopeptidase inhibitor activity(GO:0008191)
0.1
2.3
GO:0070411
I-SMAD binding(GO:0070411)
0.0
1.7
GO:0050699
WW domain binding(GO:0050699)
0.0
1.6
GO:0001671
ATPase activator activity(GO:0001671)
0.1
1.5
GO:0044548
S100 protein binding(GO:0044548)
0.1
1.3
GO:0005225
volume-sensitive anion channel activity(GO:0005225)
0.0
1.2
GO:1990381
ubiquitin-specific protease binding(GO:1990381)
0.0
1.2
GO:0005540
hyaluronic acid binding(GO:0005540)
0.3
1.1
GO:0099609
microtubule lateral binding(GO:0099609)
Showing 1 to 10 of 81 entries
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Gene overrepresentation in C2:CP category:
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Log-likelihood per target
Total log-likelihood
Term
Description
0.1
5.5
PID ECADHERIN NASCENT AJ PATHWAY
E-cadherin signaling in the nascent adherens junction
0.0
3.9
PID TGFBR PATHWAY
TGF-beta receptor signaling
0.0
2.3
PID RHOA PATHWAY
RhoA signaling pathway
0.0
1.8
ST GRANULE CELL SURVIVAL PATHWAY
Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0
1.6
PID INTEGRIN5 PATHWAY
Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0
1.2
PID TOLL ENDOGENOUS PATHWAY
Endogenous TLR signaling
0.0
1.1
PID SYNDECAN 3 PATHWAY
Syndecan-3-mediated signaling events
0.0
1.1
PID IL1 PATHWAY
IL1-mediated signaling events
0.0
1.0
PID NCADHERIN PATHWAY
N-cadherin signaling events
0.0
1.0
PID BCR 5PATHWAY
BCR signaling pathway
Showing 1 to 10 of 20 entries
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Gene overrepresentation in C2:CP:REACTOME category:
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entries
Log-likelihood per target
Total log-likelihood
Term
Description
0.1
3.1
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING
Genes involved in Downregulation of TGF-beta receptor signaling
0.0
2.3
REACTOME GENERATION OF SECOND MESSENGER MOLECULES
Genes involved in Generation of second messenger molecules
0.0
2.2
REACTOME NEPHRIN INTERACTIONS
Genes involved in Nephrin interactions
0.0
2.2
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS
Genes involved in Golgi Associated Vesicle Biogenesis
0.0
2.2
REACTOME TOLL RECEPTOR CASCADES
Genes involved in Toll Receptor Cascades
0.1
1.6
REACTOME CTNNB1 PHOSPHORYLATION CASCADE
Genes involved in Beta-catenin phosphorylation cascade
0.0
1.2
REACTOME CS DS DEGRADATION
Genes involved in CS/DS degradation
0.0
1.1
REACTOME CALNEXIN CALRETICULIN CYCLE
Genes involved in Calnexin/calreticulin cycle
0.0
1.1
REACTOME INSULIN SYNTHESIS AND PROCESSING
Genes involved in Insulin Synthesis and Processing
0.0
1.0
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE
Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
Showing 1 to 10 of 32 entries
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