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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for UAGUGUU
Z-value: 1.50
Activity profile of UAGUGUU motif
Sorted Z-values of UAGUGUU motif
Network of associatons between targets according to the STRING database.
First level regulatory network of UAGUGUU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.8 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.4 | 1.3 | GO:0031106 | septin ring assembly(GO:0000921) septin ring organization(GO:0031106) |
| 0.3 | 1.2 | GO:0061763 | multivesicular body-lysosome fusion(GO:0061763) |
| 0.3 | 2.3 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.3 | 1.0 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.2 | 1.1 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.2 | 0.8 | GO:1904501 | glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) |
| 0.2 | 0.9 | GO:1905071 | occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075) |
| 0.2 | 1.4 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.2 | 0.9 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.1 | 0.4 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 0.1 | 1.0 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.1 | 0.5 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
| 0.1 | 1.3 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.1 | 0.3 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.1 | 0.3 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.1 | 0.7 | GO:0045196 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.1 | 0.7 | GO:0034670 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.1 | 0.3 | GO:0050904 | diapedesis(GO:0050904) |
| 0.1 | 1.4 | GO:1900086 | positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086) |
| 0.1 | 0.3 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) |
| 0.1 | 0.3 | GO:1904761 | negative regulation of myofibroblast differentiation(GO:1904761) |
| 0.1 | 0.7 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 0.5 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.1 | 0.4 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.1 | 0.5 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.1 | 0.8 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.1 | 1.0 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.1 | 1.0 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.1 | 1.4 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 0.8 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.1 | 0.3 | GO:0046116 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.1 | 0.4 | GO:2001038 | regulation of cellular response to drug(GO:2001038) |
| 0.1 | 0.4 | GO:0097676 | histone H3-K36 dimethylation(GO:0097676) |
| 0.1 | 0.5 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 0.3 | GO:1903613 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.1 | 0.5 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.1 | 0.5 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.1 | 0.4 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 0.1 | 0.2 | GO:1902309 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.1 | 0.5 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.1 | 0.5 | GO:1904382 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
| 0.1 | 0.4 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.1 | 0.6 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 0.5 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.0 | 0.7 | GO:0060613 | fat pad development(GO:0060613) |
| 0.0 | 0.2 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.0 | 0.3 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.0 | 0.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.3 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.0 | 0.3 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.0 | 0.3 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.0 | 2.4 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
| 0.0 | 0.2 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 0.0 | 0.6 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 0.1 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.0 | 0.3 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.0 | 1.2 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.0 | 0.7 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 0.2 | GO:0071874 | cellular response to norepinephrine stimulus(GO:0071874) |
| 0.0 | 0.8 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.0 | 0.3 | GO:0033029 | regulation of neutrophil apoptotic process(GO:0033029) |
| 0.0 | 1.0 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 0.0 | 0.3 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.0 | 0.6 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 1.0 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.4 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.0 | 0.5 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.0 | 0.5 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.0 | 0.3 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.0 | 0.2 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.0 | 0.4 | GO:1905216 | positive regulation of RNA binding(GO:1905216) |
| 0.0 | 0.3 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.0 | 0.4 | GO:0032328 | alanine transport(GO:0032328) |
| 0.0 | 0.4 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 1.0 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.6 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.5 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.0 | 0.7 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 0.8 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.0 | 0.2 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.0 | 0.6 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.0 | 0.9 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 0.0 | 0.1 | GO:1903233 | regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515) |
| 0.0 | 0.4 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
| 0.0 | 0.1 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.0 | 0.6 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.0 | 0.1 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.0 | 0.1 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.0 | 0.1 | GO:0018032 | protein amidation(GO:0018032) |
| 0.0 | 0.2 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.0 | 0.3 | GO:0070141 | response to UV-A(GO:0070141) |
| 0.0 | 0.2 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.0 | 0.2 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.0 | 0.1 | GO:0035669 | TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669) |
| 0.0 | 0.1 | GO:0060352 | cell adhesion molecule production(GO:0060352) |
| 0.0 | 0.4 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.0 | 0.4 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 0.9 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 0.1 | GO:1904566 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.0 | 0.3 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.0 | 0.6 | GO:0010965 | metaphase/anaphase transition of mitotic cell cycle(GO:0007091) regulation of mitotic sister chromatid separation(GO:0010965) metaphase/anaphase transition of cell cycle(GO:0044784) |
| 0.0 | 0.1 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 0.0 | 0.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 0.5 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 0.1 | GO:0001878 | response to yeast(GO:0001878) |
| 0.0 | 0.2 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.2 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.0 | 0.2 | GO:0003413 | chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) |
| 0.0 | 0.6 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.0 | 0.8 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 0.1 | GO:0031577 | spindle checkpoint(GO:0031577) |
| 0.0 | 0.1 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.0 | 0.1 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.0 | 0.7 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 1.0 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
| 0.0 | 0.5 | GO:0007184 | SMAD protein import into nucleus(GO:0007184) |
| 0.0 | 1.2 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.0 | 1.9 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 0.3 | GO:0044705 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.0 | 0.8 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.5 | GO:1902808 | positive regulation of cell cycle G1/S phase transition(GO:1902808) |
| 0.0 | 0.4 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 0.2 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
| 0.0 | 0.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.2 | GO:0044308 | axonal spine(GO:0044308) |
| 0.2 | 1.3 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.2 | 2.8 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 0.8 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.1 | 0.4 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.1 | 0.5 | GO:0031213 | RSF complex(GO:0031213) |
| 0.1 | 1.4 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 0.5 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 0.1 | 0.3 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.1 | 0.4 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 0.1 | 0.8 | GO:0070369 | Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.1 | 0.5 | GO:0005606 | laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260) |
| 0.1 | 0.7 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.1 | 1.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.1 | 0.9 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.4 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.1 | 0.3 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.1 | 1.2 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.1 | 1.0 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 0.9 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.6 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 0.3 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.1 | 0.3 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.1 | 0.8 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 1.0 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.7 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.8 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 0.6 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 0.1 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.0 | 0.6 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.0 | 0.8 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 1.1 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.5 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.4 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 0.5 | GO:0001939 | female pronucleus(GO:0001939) |
| 0.0 | 0.5 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.6 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.4 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.6 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.0 | 0.5 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.6 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.4 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.5 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.5 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 0.3 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 2.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.7 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.0 | 0.9 | GO:1990752 | microtubule end(GO:1990752) |
| 0.0 | 0.2 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.0 | 0.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 1.6 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.3 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 1.4 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 0.1 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 0.7 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.8 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 2.0 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 1.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 1.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.1 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.3 | 1.0 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.2 | 0.5 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.1 | 0.4 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.1 | 0.6 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.1 | 0.4 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 0.6 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.1 | 0.6 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 0.3 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.1 | 0.4 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.1 | 0.5 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.1 | 2.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.5 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 2.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.1 | 0.7 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.1 | 3.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 0.5 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 0.7 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 0.3 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.1 | 0.8 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 1.3 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 0.8 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.1 | 1.5 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 0.9 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.0 | 0.5 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 1.0 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 1.0 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.9 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 0.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 1.2 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.8 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.3 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) protein antigen binding(GO:1990405) |
| 0.0 | 1.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.5 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 1.6 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.5 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 1.0 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.3 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.0 | 0.1 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.0 | 1.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.4 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.0 | 0.4 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 0.2 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.0 | 0.6 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.2 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.0 | 1.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.0 | 0.2 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.0 | 0.3 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.0 | 0.1 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.0 | 0.1 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.0 | 0.2 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.0 | 0.4 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 1.1 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.2 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.0 | 0.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.2 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 0.9 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.3 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.0 | 0.2 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.0 | 0.3 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 0.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.1 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.0 | 0.2 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.0 | 0.2 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 0.3 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.6 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.2 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.5 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.3 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.0 | 0.2 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 1.1 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.3 | GO:0005351 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.5 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.6 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.7 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 0.7 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 3.9 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.1 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.8 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 1.8 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.0 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 2.3 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 1.1 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.4 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 0.7 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.3 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.0 | 0.8 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 1.0 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 0.6 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 1.0 | PID FANCONI PATHWAY | Fanconi anemia pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 0.9 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.1 | 1.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 1.1 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 1.0 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 2.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 2.3 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.3 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.0 | 1.2 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 1.0 | REACTOME PROLONGED ERK ACTIVATION EVENTS | Genes involved in Prolonged ERK activation events |
| 0.0 | 1.1 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.5 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 0.5 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 2.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.7 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 0.6 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 0.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.6 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.5 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.0 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.0 | 1.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 2.2 | REACTOME TOLL RECEPTOR CASCADES | Genes involved in Toll Receptor Cascades |
| 0.0 | 1.0 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.3 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.3 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.2 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.4 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |