Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for UCACAGU

Z-value: 0.92

Motif logo

miRNA associated with seed UCACAGU

NamemiRBASE accession
MIMAT0000084
MIMAT0000419

Activity profile of UCACAGU motif

Sorted Z-values of UCACAGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UCACAGU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 0.8 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.7 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.5 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 1.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.5 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 0.6 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.6 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.4 GO:1900180 regulation of protein localization to nucleus(GO:1900180)
0.1 0.4 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.6 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.5 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.1 0.7 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.1 0.8 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 1.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.3 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.5 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.1 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.5 GO:0097114 NMDA glutamate receptor clustering(GO:0097114) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.3 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.1 0.4 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.1 0.3 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.7 GO:0046836 glycolipid transport(GO:0046836)
0.1 0.2 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 1.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.5 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.3 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.4 GO:0070417 cellular response to cold(GO:0070417)
0.1 1.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 1.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.3 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1 0.2 GO:0007538 primary sex determination(GO:0007538)
0.1 0.6 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.1 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.1 GO:0007493 endodermal cell fate determination(GO:0007493)
0.1 0.5 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.1 GO:0035627 ceramide transport(GO:0035627)
0.1 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.2 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.2 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 1.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.2 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.2 GO:1905026 regulation of heart looping(GO:1901207) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 1.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.1 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.2 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.4 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.5 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.4 GO:0003383 apical constriction(GO:0003383)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.5 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.7 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0061184 positive regulation of dermatome development(GO:0061184) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0021553 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) olfactory nerve development(GO:0021553)
0.0 1.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.3 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.3 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.3 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.7 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0072300 positive regulation of metanephric glomerulus development(GO:0072300)
0.0 0.1 GO:0055074 calcium ion homeostasis(GO:0055074) divalent inorganic cation homeostasis(GO:0072507)
0.0 0.7 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.7 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0032525 regulation of somitogenesis(GO:0014807) somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 2.4 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.0 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.0 1.0 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.4 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.0 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:1904238 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) pericyte cell differentiation(GO:1904238)
0.0 0.8 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.5 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.3 GO:0060973 cell migration involved in heart development(GO:0060973)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.9 GO:0006301 postreplication repair(GO:0006301)
0.0 0.4 GO:0060074 synapse maturation(GO:0060074)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.0 GO:0031620 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0045542 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) positive regulation of cholesterol biosynthetic process(GO:0045542) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.2 0.5 GO:1990032 parallel fiber(GO:1990032)
0.2 1.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.5 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 1.3 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.7 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.7 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 0.5 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0030662 coated vesicle membrane(GO:0030662) clathrin-coated vesicle membrane(GO:0030665)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 0.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 0.5 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.7 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.2 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 2.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.4 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 1.7 GO:0043236 laminin binding(GO:0043236)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0004104 choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995) PTB domain binding(GO:0051425)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 3.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 2.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.9 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 2.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.3 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN