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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for UGCAUAG

Z-value: 1.46

Motif logo

miRNA associated with seed UGCAUAG

NamemiRBASE accession
MIMAT0000439

Activity profile of UGCAUAG motif

Sorted Z-values of UGCAUAG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UGCAUAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.6 2.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.6 2.3 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.6 1.7 GO:0033241 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.5 1.0 GO:0048565 digestive tract development(GO:0048565)
0.5 1.9 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.4 2.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 1.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.3 1.4 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.3 1.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.2 1.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 1.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.2 0.5 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.2 1.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.7 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.2 4.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 1.1 GO:1902617 response to fluoride(GO:1902617)
0.2 0.9 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 0.9 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.9 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.2 1.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 0.5 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.2 0.8 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 2.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 0.5 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 1.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.5 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.2 1.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.2 3.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 1.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 0.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 1.5 GO:0015820 leucine transport(GO:0015820)
0.1 0.4 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.4 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.8 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.8 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.5 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.7 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.7 GO:0051643 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) endoplasmic reticulum localization(GO:0051643)
0.1 0.5 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0048840 otolith development(GO:0048840)
0.1 0.5 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 1.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.3 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 1.1 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.8 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 0.7 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.0 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 2.1 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.2 GO:0070781 response to biotin(GO:0070781)
0.1 1.7 GO:0060004 reflex(GO:0060004)
0.1 1.5 GO:0007614 short-term memory(GO:0007614)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.9 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.2 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 1.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.1 GO:0046619 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.0 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.3 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 1.0 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.5 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 1.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.0 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 1.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.9 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.9 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.7 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 1.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.3 GO:0031116 microtubule nucleation(GO:0007020) positive regulation of microtubule polymerization(GO:0031116)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 1.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.4 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.5 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:1902683 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) regulation of receptor localization to synapse(GO:1902683)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.5 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.6 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.0 2.9 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.2 GO:1902035 abscission(GO:0009838) positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.5 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.3 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.3 GO:0060074 synapse maturation(GO:0060074)
0.0 0.4 GO:0040008 regulation of growth(GO:0040008)
0.0 0.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.3 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.9 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 3.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.2 2.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 0.9 GO:0043260 laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260)
0.2 2.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 0.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 1.0 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 4.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.8 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 2.2 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.0 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 1.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.5 GO:0032433 filopodium tip(GO:0032433)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.1 0.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.1 GO:0032059 bleb(GO:0032059)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.7 GO:0008091 spectrin(GO:0008091)
0.0 3.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 6.4 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.0 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 1.3 GO:0005768 endosome(GO:0005768)
0.0 0.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.6 1.7 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.5 1.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.4 1.9 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.9 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.2 1.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.5 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 1.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 2.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 2.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 1.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0052842 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.3 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.1 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 1.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 4.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.8 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 2.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0097617 RNA strand annealing activity(GO:0033592) annealing activity(GO:0097617)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 1.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0000975 regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 2.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.5 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 3.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 3.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 3.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 2.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis