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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for UUGGCAC

Z-value: 0.86

Motif logo

miRNA associated with seed UUGGCAC

NamemiRBASE accession
MIMAT0000095
MIMAT0005796

Activity profile of UUGGCAC motif

Sorted Z-values of UUGGCAC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UUGGCAC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 1.2 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.3 2.0 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 0.8 GO:0033241 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.3 1.3 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.2 0.7 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.2 0.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 0.7 GO:0021503 neural fold bending(GO:0021503)
0.2 0.7 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 0.5 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.5 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 0.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 0.8 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.0 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 1.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 0.9 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.2 0.5 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.7 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 3.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.5 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.4 GO:0035349 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.4 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 2.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 2.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.4 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.8 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.2 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.1 0.2 GO:0007493 endodermal cell fate determination(GO:0007493)
0.1 0.3 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.3 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.4 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 1.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.6 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.2 GO:0046041 ITP metabolic process(GO:0046041)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.5 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.5 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 2.7 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.4 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 0.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.5 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.2 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.1 0.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.2 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.3 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.3 GO:0014028 notochord formation(GO:0014028)
0.0 0.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:0048539 bone marrow development(GO:0048539)
0.0 0.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.8 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0036269 swimming behavior(GO:0036269)
0.0 0.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.5 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.2 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.4 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0032489 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.5 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.5 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.7 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.3 GO:0032439 endosome localization(GO:0032439)
0.0 0.7 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.3 GO:0070779 sulfur amino acid transport(GO:0000101) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0090169 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.7 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.3 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.8 GO:0015695 organic cation transport(GO:0015695)
0.0 1.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.0 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.7 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 1.0 GO:0016577 histone demethylation(GO:0016577)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 2.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 1.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.3 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.2 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.8 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713) Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.5 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.4 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.0 GO:0046839 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.3 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.2 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.5 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 0.8 GO:1990032 parallel fiber(GO:1990032)
0.3 1.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.2 1.0 GO:0044308 axonal spine(GO:0044308)
0.1 2.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.6 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.3 GO:0000806 Y chromosome(GO:0000806)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.3 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.3 GO:0005606 laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0051286 cell tip(GO:0051286)
0.0 0.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 2.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 1.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.9 GO:1990752 microtubule end(GO:1990752)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0044309 neuron spine(GO:0044309)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0008431 vitamin E binding(GO:0008431)
0.3 0.8 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 1.3 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.2 1.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.6 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 0.7 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.4 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 2.0 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.5 GO:0035473 lipase binding(GO:0035473)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.5 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.2 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.2 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 1.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0043394 proteoglycan binding(GO:0043394)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 ST ADRENERGIC Adrenergic Pathway
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 1.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 3.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo