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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for VAX1_GSX2

Z-value: 1.53

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Transcription factors associated with VAX1_GSX2

Gene Symbol Gene ID Gene Info
ENSG00000148704.8 ventral anterior homeobox 1
ENSG00000180613.6 GS homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VAX1hg19_v2_chr10_-_118897806_1188978170.891.2e-07Click!

Activity profile of VAX1_GSX2 motif

Sorted Z-values of VAX1_GSX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX1_GSX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.6 1.8 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.6 2.4 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.4 3.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.4 1.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.4 1.4 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.3 1.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3 0.9 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.3 1.7 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.3 0.8 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 1.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 2.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.7 GO:0015811 L-cystine transport(GO:0015811)
0.2 1.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 0.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 1.9 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 1.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 0.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.9 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.6 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1 2.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 2.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.9 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 1.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 1.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.4 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.9 GO:0030242 pexophagy(GO:0030242)
0.1 0.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.7 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.5 GO:0061150 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.5 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 2.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.9 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 2.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.4 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 1.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.7 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.2 GO:1900241 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.5 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.3 GO:0050955 thermoception(GO:0050955)
0.0 1.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.3 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 1.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.9 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 1.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 3.2 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.8 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.2 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.9 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.3 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 3.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.0 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.5 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.0 GO:0008542 visual learning(GO:0008542)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.2 1.0 GO:0005873 plus-end kinesin complex(GO:0005873)
0.2 1.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 3.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.8 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.9 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 2.8 GO:0042627 chylomicron(GO:0042627)
0.1 1.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.7 GO:0070938 contractile ring(GO:0070938)
0.1 0.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.3 GO:0071547 piP-body(GO:0071547)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.6 GO:0034709 methylosome(GO:0034709)
0.0 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.6 GO:0000792 heterochromatin(GO:0000792)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 1.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.3 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.5 2.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.3 1.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 0.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.3 1.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 1.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 1.7 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 3.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 0.6 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.2 1.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 1.2 GO:0043532 angiostatin binding(GO:0043532)
0.1 3.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 1.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.0 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 1.5 GO:0000150 recombinase activity(GO:0000150)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 1.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.6 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849) virion binding(GO:0046790)
0.0 1.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 2.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 2.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 2.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.5 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 3.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.4 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 0.6 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 3.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC