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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for VAX1_GSX2
Z-value: 1.53
Motif logo
Transcription factors associated with VAX1_GSX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
VAX1
|
ENSG00000148704.8 | ventral anterior homeobox 1 |
|
GSX2
|
ENSG00000180613.6 | GS homeobox 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| VAX1 | hg19_v2_chr10_-_118897806_118897817 | 0.89 | 1.2e-07 | Click! |
Activity profile of VAX1_GSX2 motif
Sorted Z-values of VAX1_GSX2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of VAX1_GSX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.9 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.6 | 1.8 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.6 | 2.4 | GO:2000866 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
| 0.4 | 3.3 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.4 | 1.4 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 0.4 | 1.4 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
| 0.3 | 1.4 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.3 | 0.9 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.3 | 1.7 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.3 | 0.8 | GO:0051795 | positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427) |
| 0.2 | 1.7 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.2 | 2.0 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.2 | 1.7 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.2 | 1.9 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.2 | 0.6 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
| 0.2 | 1.9 | GO:0018317 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.2 | 1.7 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 0.2 | 0.5 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 0.2 | 0.6 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.1 | 0.9 | GO:0010816 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.1 | 0.6 | GO:0044053 | translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836) |
| 0.1 | 2.4 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 1.2 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.1 | 0.4 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
| 0.1 | 0.3 | GO:2000053 | regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) |
| 0.1 | 2.1 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.9 | GO:0000066 | mitochondrial ornithine transport(GO:0000066) |
| 0.1 | 1.3 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.1 | 1.2 | GO:0019344 | cysteine biosynthetic process(GO:0019344) |
| 0.1 | 0.4 | GO:0036367 | adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367) |
| 0.1 | 0.9 | GO:0030242 | pexophagy(GO:0030242) |
| 0.1 | 0.7 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.1 | 0.7 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.1 | 0.5 | GO:0061150 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
| 0.1 | 0.5 | GO:0070980 | biphenyl catabolic process(GO:0070980) |
| 0.1 | 2.4 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.1 | 0.9 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 0.6 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.1 | 0.3 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.1 | 0.3 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.1 | 2.9 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 0.4 | GO:0052199 | negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199) |
| 0.1 | 1.7 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.1 | 0.7 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 0.1 | 0.2 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.1 | 0.3 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.1 | 0.3 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.1 | 0.2 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.1 | 0.2 | GO:1900241 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.1 | 0.5 | GO:0032233 | positive regulation of actin filament bundle assembly(GO:0032233) |
| 0.1 | 0.2 | GO:0061743 | motor learning(GO:0061743) |
| 0.0 | 0.2 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168) |
| 0.0 | 0.5 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.0 | 0.3 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 0.0 | 0.3 | GO:0050955 | thermoception(GO:0050955) |
| 0.0 | 1.1 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.0 | 0.2 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.0 | 0.2 | GO:1904823 | pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823) |
| 0.0 | 0.3 | GO:0071877 | regulation of adrenergic receptor signaling pathway(GO:0071877) |
| 0.0 | 0.5 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 1.0 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.0 | 1.9 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.0 | 0.2 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.0 | 0.2 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 0.0 | 1.7 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.9 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.0 | 0.2 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.0 | 0.1 | GO:0045208 | MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209) |
| 0.0 | 3.2 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 1.2 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.0 | 0.6 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.0 | 0.3 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.0 | 0.8 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.8 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 0.5 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.5 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 0.0 | 0.1 | GO:0006429 | glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429) |
| 0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.0 | 0.1 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.0 | 1.2 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
| 0.0 | 0.1 | GO:1902769 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.0 | 0.6 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.5 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.0 | 1.9 | GO:0042246 | tissue regeneration(GO:0042246) |
| 0.0 | 0.3 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 0.0 | 3.0 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 1.0 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.0 | 0.5 | GO:0071305 | cellular response to vitamin D(GO:0071305) |
| 0.0 | 0.1 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.0 | 0.2 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.0 | 0.1 | GO:0072752 | cellular response to rapamycin(GO:0072752) |
| 0.0 | 0.4 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.0 | 0.3 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.0 | 0.4 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.0 | 0.2 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.0 | 0.1 | GO:0000270 | peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) |
| 0.0 | 0.7 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.1 | GO:0009086 | methionine biosynthetic process(GO:0009086) |
| 0.0 | 0.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 1.0 | GO:0008542 | visual learning(GO:0008542) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 2.9 | GO:0043614 | multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451) |
| 0.2 | 1.0 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.2 | 1.9 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.2 | 1.2 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
| 0.2 | 3.8 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.1 | 1.8 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.1 | 0.9 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.1 | 2.8 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 1.5 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 1.7 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 0.8 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.1 | 1.7 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 0.5 | GO:0090661 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 0.3 | GO:0071547 | piP-body(GO:0071547) |
| 0.1 | 0.6 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 0.7 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.0 | 0.6 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.4 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.2 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 0.9 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.8 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 1.4 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.6 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.0 | 0.6 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 0.4 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.6 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 1.2 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 2.6 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.0 | 1.2 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 1.9 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 1.6 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.8 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 3.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 1.3 | GO:0015629 | actin cytoskeleton(GO:0015629) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.3 | GO:0018636 | phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) |
| 0.5 | 2.4 | GO:0008665 | 2'-phosphotransferase activity(GO:0008665) |
| 0.3 | 1.0 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 0.3 | 0.9 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.3 | 1.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.3 | 1.3 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.2 | 1.7 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.2 | 0.6 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.2 | 3.8 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.2 | 0.6 | GO:0050571 | 1,5-anhydro-D-fructose reductase activity(GO:0050571) |
| 0.2 | 1.4 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.2 | 1.2 | GO:0043532 | angiostatin binding(GO:0043532) |
| 0.1 | 3.0 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 0.9 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
| 0.1 | 0.2 | GO:0005275 | amine transmembrane transporter activity(GO:0005275) |
| 0.1 | 1.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 2.6 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.1 | 0.4 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.1 | 0.9 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 1.0 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 0.1 | 1.5 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.1 | 0.2 | GO:0010309 | acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309) |
| 0.1 | 0.3 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.1 | 1.2 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.1 | 0.6 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.1 | 0.3 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.1 | 0.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 1.9 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.1 | 0.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.2 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.0 | 0.5 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.0 | 0.2 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 0.0 | 0.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.3 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.0 | 0.4 | GO:0001849 | complement component C1q binding(GO:0001849) virion binding(GO:0046790) |
| 0.0 | 1.7 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.3 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.0 | 2.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.6 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.2 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.0 | 0.3 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.0 | 0.5 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 1.0 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.0 | 0.2 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.0 | 2.9 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.1 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.0 | 0.9 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 1.5 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 2.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.5 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 1.3 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.2 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.0 | 0.1 | GO:0004823 | glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823) |
| 0.0 | 0.4 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.0 | 0.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 2.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.7 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 0.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.4 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.0 | 2.2 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.9 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.0 | 0.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.7 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.5 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 1.5 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.0 | 0.1 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.0 | 0.6 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 1.7 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.2 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 2.4 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 2.3 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 3.1 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 2.0 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.0 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 1.9 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 0.9 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.4 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 0.6 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.5 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.3 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 0.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.5 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.1 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 1.3 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.6 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 2.3 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 3.4 | REACTOME PERK REGULATED GENE EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.1 | 0.6 | REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |
| 0.1 | 1.2 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 3.2 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 1.7 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 0.3 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 1.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 1.8 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.9 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 1.0 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.7 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.2 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.2 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 2.7 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 2.4 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.6 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |