ISMARA results: XBP1

Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for XBP1

Z-value: 2.89

Motif logo

Transcription factors associated with XBP1

Gene Symbol	Gene ID	Gene Info
XBP1 Ensembl NCBI GeneCards UniProt	ENSG00000100219.12	X-box binding protein 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
XBP1	hg19_v2_chr22_-_29196546_29196585	-0.26	2.7e-01	Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

No targets for XBP1

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	13.3	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.2	7.4	GO:0006882	cellular zinc ion homeostasis(GO:0006882) zinc II ion transmembrane transport(GO:0071577)
0.6	6.9	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.3	6.5	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
1.3	5.1	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2	5.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	4.8	GO:0001649	osteoblast differentiation(GO:0001649)
0.1	4.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
1.1	4.4	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.3	4.3	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)

Showing 1 to 10 of 85 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	32.1	GO:0005794	Golgi apparatus(GO:0005794)
1.3	6.3	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	5.8	GO:0002102	podosome(GO:0002102)
0.0	5.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	5.0	GO:0001650	fibrillar center(GO:0001650)
0.2	4.9	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	4.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	4.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.2	3.8	GO:0032039	integrator complex(GO:0032039)
0.2	3.6	GO:0030126	COPI vesicle coat(GO:0030126)

Showing 1 to 10 of 55 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	15.8	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.2	7.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	7.4	GO:0008565	protein transporter activity(GO:0008565)
1.6	6.3	GO:0070012	oligopeptidase activity(GO:0070012)
0.0	5.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3	4.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.1	4.4	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.1	4.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	4.0	GO:0000149	SNARE binding(GO:0000149)
0.7	3.5	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)

Showing 1 to 10 of 63 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	13.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	6.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	6.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	4.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	3.9	PID FOXO PATHWAY	FoxO family signaling
0.1	3.8	PID ARF 3PATHWAY	Arf1 pathway
0.0	3.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	3.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	3.1	PID RAS PATHWAY	Regulation of Ras family activation
0.1	3.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway

Showing 1 to 10 of 21 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	15.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.2	7.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	6.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	6.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	5.4	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	4.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3	4.0	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.2	3.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	3.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	2.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway

Showing 1 to 10 of 31 entries

Results for XBP1

Z-value: 2.89

Motif logo

Transcription factors associated with XBP1

Activity-expression correlation:

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

No targets for XBP1

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: