ISMARA results: YBX1_FOS_NFYC_NFYA_NFYB

Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

Z-value: 10.98

Motif logo

Transcription factors associated with YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

Gene Symbol	Gene ID	Gene Info
YBX1 Ensembl NCBI GeneCards UniProt	ENSG00000065978.13	Y-box binding protein 1
FOS Ensembl NCBI GeneCards UniProt	ENSG00000170345.5	Fos proto-oncogene, AP-1 transcription factor subunit
NFYC Ensembl NCBI GeneCards UniProt	ENSG00000066136.15	nuclear transcription factor Y subunit gamma
NFYA Ensembl NCBI GeneCards UniProt	ENSG00000001167.10	nuclear transcription factor Y subunit alpha
NFYB Ensembl NCBI GeneCards UniProt	ENSG00000120837.3	nuclear transcription factor Y subunit beta
CEBPZ Ensembl NCBI GeneCards UniProt	ENSG00000115816.9	CCAAT enhancer binding protein zeta

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NFYB	hg19_v2_chr12_-_104531945_104531996	0.87	4.9e-07	Click!
NFYC	hg19_v2_chr1_+_41157361_41157416	0.82	1.0e-05	Click!
CEBPZ	hg19_v2_chr2_-_37458749_37458856	0.81	1.4e-05	Click!
FOS	hg19_v2_chr14_+_75746340_75746373	-0.81	1.5e-05	Click!
YBX1	hg19_v2_chr1_+_43148625_43148710	-0.65	1.8e-03	Click!
NFYA	hg19_v2_chr6_+_41040678_41040722	0.08	7.4e-01	Click!

Activity profile of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif

Sorted Z-values of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif

No targets for YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

Network of associatons between targets according to the STRING database.

First level regulatory network of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	87.5	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
2.7	54.9	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.7	53.6	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.8	43.4	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.6	42.4	GO:0007077	mitotic nuclear envelope disassembly(GO:0007077)
4.7	37.9	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
1.4	36.6	GO:0000920	cell separation after cytokinesis(GO:0000920)
5.8	34.9	GO:0016321	female meiosis chromosome segregation(GO:0016321)
2.1	34.0	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.8	33.5	GO:0006270	DNA replication initiation(GO:0006270)

Showing 1 to 10 of 765 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	87.0	GO:0000776	kinetochore(GO:0000776)
2.1	85.5	GO:0005680	anaphase-promoting complex(GO:0005680)
0.8	69.9	GO:0005871	kinesin complex(GO:0005871)
10.4	62.7	GO:0097149	centralspindlin complex(GO:0097149)
0.4	59.1	GO:0000922	spindle pole(GO:0000922)
0.1	58.4	GO:0005635	nuclear envelope(GO:0005635)
0.6	57.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.8	53.2	GO:0000786	nucleosome(GO:0000786)
8.6	43.0	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
5.0	39.7	GO:0032133	chromosome passenger complex(GO:0032133)

Showing 1 to 10 of 324 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	84.3	GO:0003777	microtubule motor activity(GO:0003777)
9.8	68.8	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2	68.5	GO:0042393	histone binding(GO:0042393)
0.4	64.5	GO:0017048	Rho GTPase binding(GO:0017048)
0.1	49.4	GO:0015631	tubulin binding(GO:0015631)
0.8	49.2	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.5	33.8	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.5	32.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
3.6	32.7	GO:0035174	histone serine kinase activity(GO:0035174)
9.6	28.7	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)

Showing 1 to 10 of 520 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	238.5	PID PLK1 PATHWAY	PLK1 signaling events
1.8	142.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
1.4	101.6	PID FANCONI PATHWAY	Fanconi anemia pathway
0.6	42.4	PID AURORA B PATHWAY	Aurora B signaling
0.3	31.4	PID E2F PATHWAY	E2F transcription factor network
1.4	30.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.4	24.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	23.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.5	23.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.3	21.6	SIG CD40PATHWAYMAP	Genes related to CD40 signaling

Showing 1 to 10 of 79 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	184.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
2.5	91.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.3	63.4	REACTOME KINESINS	Genes involved in Kinesins
2.6	63.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
3.6	61.9	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.7	59.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
1.6	59.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.5	49.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.6	48.6	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
2.6	46.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA

Showing 1 to 10 of 133 entries

Results for YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

Z-value: 10.98

Motif logo

Transcription factors associated with YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

Activity-expression correlation:

Activity profile of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif

Sorted Z-values of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif

No targets for YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

Network of associatons between targets according to the STRING database.

First level regulatory network of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: