ISMARA results: ZBTB14

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZBTB14

Z-value: 1.64

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Transcription factors associated with ZBTB14

Gene Symbol	Gene ID	Gene Info
ZBTB14 Ensembl NCBI GeneCards UniProt	ENSG00000198081.6	zinc finger and BTB domain containing 14

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZBTB14	hg19_v2_chr18_-_5296138_5296194	0.90	5.9e-08	Click!

Activity profile of ZBTB14 motif

Sorted Z-values of ZBTB14 motif

No targets for ZBTB14

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB14

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.3	GO:0034063	stress granule assembly(GO:0034063)
0.1	2.7	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	2.7	GO:0090307	mitotic spindle assembly(GO:0090307)
0.0	2.6	GO:0090630	activation of GTPase activity(GO:0090630)
0.1	2.4	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	2.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.4	2.3	GO:1904674	positive regulation of somatic stem cell population maintenance(GO:1904674)
0.7	2.2	GO:0072387	flavin adenine dinucleotide metabolic process(GO:0072387)
0.5	2.2	GO:0001928	regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.4	2.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)

Showing 1 to 10 of 338 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.0	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	3.8	GO:0000502	proteasome complex(GO:0000502)
0.1	2.7	GO:0045180	basal cortex(GO:0045180)
0.1	2.7	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	2.4	GO:0000786	nucleosome(GO:0000786)
0.1	2.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	2.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.4	2.2	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.2	2.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	2.1	GO:0000145	exocyst(GO:0000145)

Showing 1 to 10 of 139 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.2	GO:0017124	SH3 domain binding(GO:0017124)
0.1	3.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.2	3.4	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	3.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	2.7	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	2.4	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	2.4	GO:0003777	microtubule motor activity(GO:0003777)
0.0	2.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.4	2.2	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	2.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)

Showing 1 to 10 of 198 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.8	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.1	3.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	2.8	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	2.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	2.5	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	2.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	2.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.9	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.5	ST G ALPHA I PATHWAY	G alpha i Pathway

Showing 1 to 10 of 42 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	9.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	3.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	3.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	3.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	2.7	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	2.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	2.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	2.1	REACTOME KINESINS	Genes involved in Kinesins
0.0	2.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor

Showing 1 to 10 of 70 entries

Results for ZBTB14

Z-value: 1.64

Motif logo

Transcription factors associated with ZBTB14

Activity-expression correlation:

Activity profile of ZBTB14 motif

Sorted Z-values of ZBTB14 motif

No targets for ZBTB14

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB14

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: