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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZBTB33_CHD2

Z-value: 5.25

Motif logo

Transcription factors associated with ZBTB33_CHD2

Gene Symbol Gene ID Gene Info
ENSG00000177485.6 zinc finger and BTB domain containing 33
ENSG00000173575.14 chromodomain helicase DNA binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB33hg19_v2_chrX_+_119384607_1193847200.965.2e-11Click!
CHD2hg19_v2_chr15_+_93426514_934265620.502.4e-02Click!

Activity profile of ZBTB33_CHD2 motif

Sorted Z-values of ZBTB33_CHD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB33_CHD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 10.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.1 6.2 GO:0002188 translation reinitiation(GO:0002188)
1.9 7.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
1.7 6.9 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
1.6 6.5 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
1.5 4.4 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
1.3 4.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
1.2 4.9 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
1.1 10.3 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
1.1 10.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.1 5.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
1.1 3.3 GO:0032203 telomere formation via telomerase(GO:0032203)
1.0 18.9 GO:0034501 protein localization to kinetochore(GO:0034501)
1.0 4.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
1.0 3.0 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.9 16.0 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.9 2.6 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.8 2.5 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.8 9.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.8 3.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.7 4.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.7 5.7 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.7 2.1 GO:0060733 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.7 2.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.6 3.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.6 5.1 GO:0080009 mRNA methylation(GO:0080009)
0.6 3.8 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.6 3.8 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.6 1.9 GO:0060931 sinoatrial node cell development(GO:0060931)
0.6 0.6 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.6 1.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.6 8.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.6 3.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.6 2.9 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.6 15.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.6 4.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6 1.7 GO:0006481 C-terminal protein methylation(GO:0006481)
0.6 1.7 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.6 1.7 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.5 1.6 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.5 6.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.5 3.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.5 2.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.5 2.0 GO:0036292 DNA rewinding(GO:0036292)
0.5 2.4 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.5 1.9 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 3.2 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.5 4.6 GO:0006552 leucine catabolic process(GO:0006552)
0.5 2.3 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.4 2.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.4 2.5 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.4 2.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.4 2.4 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.4 6.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.4 1.5 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.4 1.9 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.4 1.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.4 2.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.4 1.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.4 1.4 GO:1903722 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.4 3.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 1.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.3 1.0 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.3 2.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.3 3.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.3 2.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.3 4.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.3 6.8 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 0.9 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.3 2.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.3 0.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 0.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3 0.9 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.3 1.2 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.3 2.2 GO:0048549 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.3 1.7 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 3.0 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 8.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.3 1.4 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.3 1.9 GO:0051012 microtubule sliding(GO:0051012)
0.3 1.3 GO:0048478 replication fork protection(GO:0048478)
0.3 1.8 GO:0045204 MAPK export from nucleus(GO:0045204)
0.3 0.5 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.3 31.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.3 0.5 GO:0036369 transcription factor catabolic process(GO:0036369)
0.3 1.0 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 1.2 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.2 0.7 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.2 4.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 3.7 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 0.9 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 1.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 6.2 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.9 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.2 6.4 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.2 1.8 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 1.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 3.6 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 0.9 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 2.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.6 GO:0045925 positive regulation of female receptivity(GO:0045925) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 1.3 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.2 1.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 2.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.2 1.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 6.0 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 1.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 0.6 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 1.7 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.2 0.2 GO:0006839 mitochondrial transport(GO:0006839)
0.2 0.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 1.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.4 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.2 5.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.2 6.2 GO:0006907 pinocytosis(GO:0006907)
0.2 1.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 2.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.0 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.2 0.6 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2 4.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 0.9 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 3.5 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.2 1.1 GO:0015853 adenine transport(GO:0015853)
0.2 0.7 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.2 0.5 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 3.6 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.2 0.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 2.7 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 1.2 GO:0033504 floor plate development(GO:0033504)
0.2 0.8 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 0.8 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.2 7.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 2.7 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 9.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 3.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.2 2.9 GO:0000338 protein deneddylation(GO:0000338)
0.2 0.5 GO:0060032 notochord regression(GO:0060032)
0.2 1.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 3.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 10.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.8 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.9 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.6 GO:0048377 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.1 0.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.7 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 1.3 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.7 GO:0031291 mitotic chromosome movement towards spindle pole(GO:0007079) Ran protein signal transduction(GO:0031291)
0.1 1.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.7 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.7 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.7 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.7 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 1.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 2.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.8 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 2.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 2.0 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.6 GO:0006896 Golgi to vacuole transport(GO:0006896) Golgi to lysosome transport(GO:0090160)
0.1 0.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.5 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.6 GO:0048319 mesoderm migration involved in gastrulation(GO:0007509) axial mesoderm morphogenesis(GO:0048319)
0.1 0.5 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.5 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 3.8 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 2.2 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 0.6 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.5 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.0 GO:0007135 meiosis II(GO:0007135)
0.1 2.2 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 3.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.6 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.3 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 3.7 GO:0031577 spindle checkpoint(GO:0031577)
0.1 1.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 1.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 4.6 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.1 0.7 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 2.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 9.4 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 1.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 2.6 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.5 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 1.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 3.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 1.9 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.5 GO:0006983 ER overload response(GO:0006983)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.8 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:2000828 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.1 0.8 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.5 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 2.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 0.3 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 4.8 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.7 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.3 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.8 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.2 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.3 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.8 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 2.8 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.5 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 6.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 1.0 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.1 2.6 GO:0006284 base-excision repair(GO:0006284)
0.1 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.4 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 2.5 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 5.6 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 2.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 1.2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 1.7 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.7 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.6 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 4.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.9 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 1.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 3.5 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 1.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 1.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 2.6 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.0 1.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 1.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 1.6 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.3 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 3.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 3.4 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 2.2 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.9 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 3.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 4.8 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 1.5 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 1.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 1.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 3.0 GO:0014902 myotube differentiation(GO:0014902)
0.0 0.2 GO:0007369 gastrulation(GO:0007369)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.2 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 1.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 2.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0060281 regulation of oocyte development(GO:0060281)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 1.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.4 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 5.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.9 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 1.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 0.2 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 1.2 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.0 0.4 GO:0043254 regulation of protein complex assembly(GO:0043254)
0.0 0.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.6 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.2 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.5 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 2.7 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.5 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.5 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.6 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0048199 vesicle coating(GO:0006901) vesicle targeting(GO:0006903) vesicle targeting, to, from or within Golgi(GO:0048199) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 1.9 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.3 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.0 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.8 GO:0033762 response to glucagon(GO:0033762)
0.0 1.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
2.3 9.3 GO:1990423 RZZ complex(GO:1990423)
2.1 6.2 GO:0070685 macropinocytic cup(GO:0070685)
1.9 5.7 GO:0034455 t-UTP complex(GO:0034455)
1.9 5.6 GO:0035101 FACT complex(GO:0035101)
1.5 20.1 GO:0000796 condensin complex(GO:0000796)
1.3 25.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.1 10.3 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.9 1.8 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.8 4.6 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.7 7.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.6 1.9 GO:1990716 axonemal central apparatus(GO:1990716)
0.6 1.7 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.5 4.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.5 1.4 GO:0009346 citrate lyase complex(GO:0009346)
0.5 1.9 GO:0031251 PAN complex(GO:0031251)
0.4 1.7 GO:0043291 RAVE complex(GO:0043291)
0.4 9.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4 2.0 GO:0071942 XPC complex(GO:0071942)
0.4 2.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.4 3.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 7.1 GO:0044754 autolysosome(GO:0044754)
0.3 1.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.3 1.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.3 5.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 0.9 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.3 4.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 3.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 5.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.3 1.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.3 2.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.3 4.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.3 5.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.6 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 8.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 6.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 7.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 6.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 1.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 2.5 GO:0071439 clathrin complex(GO:0071439)
0.2 0.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.9 GO:0005827 polar microtubule(GO:0005827)
0.2 2.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.6 GO:0031415 NatA complex(GO:0031415)
0.2 1.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 2.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 0.6 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 3.8 GO:0097227 sperm annulus(GO:0097227)
0.2 0.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 9.1 GO:0016592 mediator complex(GO:0016592)
0.2 8.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 2.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.6 GO:0031213 RSF complex(GO:0031213)
0.2 0.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.4 GO:0000124 SAGA complex(GO:0000124)
0.1 2.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:0034657 GID complex(GO:0034657)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 3.1 GO:0000346 transcription export complex(GO:0000346)
0.1 0.6 GO:1990031 pinceau fiber(GO:1990031)
0.1 3.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 1.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 4.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.3 GO:0031298 replication fork protection complex(GO:0031298)
0.1 1.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 3.3 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 4.8 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 6.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 16.9 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 8.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.4 GO:0090543 Flemming body(GO:0090543)
0.1 1.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 11.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 7.6 GO:0005643 nuclear pore(GO:0005643)
0.1 1.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.3 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 2.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 13.0 GO:0005795 Golgi stack(GO:0005795)
0.1 0.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 3.4 GO:0044815 DNA packaging complex(GO:0044815)
0.1 2.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.4 GO:0046930 pore complex(GO:0046930)
0.0 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 2.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 4.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 11.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 5.7 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 11.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.6 GO:1990752 microtubule end(GO:1990752)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 1.4 GO:0043034 costamere(GO:0043034)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 2.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.2 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.9 GO:0005921 gap junction(GO:0005921)
0.0 1.4 GO:0015030 Cajal body(GO:0015030)
0.0 11.0 GO:0000785 chromatin(GO:0000785)
0.0 2.4 GO:0030424 axon(GO:0030424)
0.0 1.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 1.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 1.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 4.9 GO:0005819 spindle(GO:0005819)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.6 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 18.1 GO:0030350 iron-responsive element binding(GO:0030350)
1.8 7.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
1.8 17.8 GO:0043515 kinetochore binding(GO:0043515)
1.7 5.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.7 5.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.6 6.4 GO:0036033 mediator complex binding(GO:0036033)
1.1 6.5 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
1.0 3.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
1.0 2.9 GO:0030626 U12 snRNA binding(GO:0030626)
0.9 2.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.8 2.5 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.8 10.8 GO:0051525 NFAT protein binding(GO:0051525)
0.8 6.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.8 3.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.8 4.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.6 1.7 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.5 1.6 GO:0090541 MIT domain binding(GO:0090541)
0.5 2.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.5 1.4 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.5 1.9 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.5 1.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.5 3.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.5 4.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 5.7 GO:0033592 RNA strand annealing activity(GO:0033592)
0.4 8.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 8.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.4 1.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.4 3.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 1.9 GO:0031208 POZ domain binding(GO:0031208)
0.4 1.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 6.2 GO:0034452 dynactin binding(GO:0034452)
0.3 1.7 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.3 1.3 GO:0032427 GBD domain binding(GO:0032427)
0.3 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 8.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 2.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 2.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 1.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.3 12.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 1.2 GO:0098809 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.3 5.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 2.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 0.8 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 1.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 0.8 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.3 4.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 2.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 3.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.3 1.0 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.2 0.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 0.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 2.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 1.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.9 GO:0031685 adenosine receptor binding(GO:0031685)
0.2 1.8 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2 2.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 1.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.2 2.5 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.2 1.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 1.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 2.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 0.6 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2 1.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 6.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 1.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 2.3 GO:0043199 sulfate binding(GO:0043199)
0.2 2.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.5 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.6 GO:0004461 lactose synthase activity(GO:0004461)
0.1 6.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 4.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.7 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.1 5.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 8.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.8 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 5.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.8 GO:0015288 porin activity(GO:0015288)
0.1 1.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 11.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.5 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 3.1 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 3.0 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 2.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.8 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.3 GO:0071208 histone pre-mRNA stem-loop binding(GO:0071207) histone pre-mRNA DCP binding(GO:0071208)
0.1 2.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 4.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 3.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 4.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 8.5 GO:0050681 androgen receptor binding(GO:0050681)
0.1 2.6 GO:0005112 Notch binding(GO:0005112)
0.1 15.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.8 GO:0000150 recombinase activity(GO:0000150)
0.1 4.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.1 20.1 GO:0004386 helicase activity(GO:0004386)
0.1 3.3 GO:0005123 death receptor binding(GO:0005123)
0.1 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 2.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 2.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 3.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 2.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 4.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.1 GO:0004803 transposase activity(GO:0004803)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.2 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.1 0.6 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 1.3 GO:0043560 neurotrophin TRKA receptor binding(GO:0005168) insulin receptor substrate binding(GO:0043560)
0.1 2.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 2.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 3.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 4.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.0 GO:0005542 folic acid binding(GO:0005542)
0.0 1.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 15.0 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.6 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0009881 photoreceptor activity(GO:0009881)
0.0 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.7 GO:0010181 FMN binding(GO:0010181)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 1.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 2.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0031628 opioid peptide activity(GO:0001515) opioid receptor binding(GO:0031628)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 1.9 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.7 GO:0003924 GTPase activity(GO:0003924)
0.0 1.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 4.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 5.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.4 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.3 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 5.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)
0.0 12.1 GO:0045296 cadherin binding(GO:0045296)
0.0 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 1.2 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.5 GO:0051087 chaperone binding(GO:0051087)
0.0 5.9 GO:0005525 GTP binding(GO:0005525)
0.0 0.0 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 19.4 PID AURORA B PATHWAY Aurora B signaling
0.2 23.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 2.5 PID MYC PATHWAY C-MYC pathway
0.2 14.4 PID PLK1 PATHWAY PLK1 signaling events
0.2 8.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 24.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 9.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 4.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 5.7 PID ATM PATHWAY ATM pathway
0.1 6.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 14.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.3 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 4.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.7 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.0 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.3 PID ATR PATHWAY ATR signaling pathway
0.0 1.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 13.8 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.4 10.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.4 2.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 11.7 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.3 8.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 4.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 4.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 9.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 8.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 3.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 5.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 4.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 2.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 0.3 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.2 5.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 2.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 23.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 8.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 3.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 15.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 3.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 10.2 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 0.5 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 6.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 6.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 7.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 10.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 2.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 10.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 1.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 10.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 2.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 4.7 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis