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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for ZBTB33_CHD2
Z-value: 5.25
Motif logo
Transcription factors associated with ZBTB33_CHD2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ZBTB33
|
ENSG00000177485.6 | zinc finger and BTB domain containing 33 |
|
CHD2
|
ENSG00000173575.14 | chromodomain helicase DNA binding protein 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZBTB33 | hg19_v2_chrX_+_119384607_119384720 | 0.96 | 5.2e-11 | Click! |
| CHD2 | hg19_v2_chr15_+_93426514_93426562 | 0.50 | 2.4e-02 | Click! |
Activity profile of ZBTB33_CHD2 motif
Sorted Z-values of ZBTB33_CHD2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ZBTB33_CHD2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 10.8 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 2.1 | 6.2 | GO:0002188 | translation reinitiation(GO:0002188) |
| 1.9 | 7.5 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 1.7 | 6.9 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168) |
| 1.6 | 6.5 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 1.5 | 4.4 | GO:0035508 | positive regulation of myosin-light-chain-phosphatase activity(GO:0035508) |
| 1.3 | 4.0 | GO:0002023 | reduction of food intake in response to dietary excess(GO:0002023) |
| 1.2 | 4.9 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 1.1 | 10.3 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 1.1 | 10.3 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 1.1 | 5.6 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 1.1 | 3.3 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 1.0 | 18.9 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 1.0 | 4.9 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 1.0 | 3.0 | GO:0071301 | cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404) |
| 0.9 | 16.0 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) |
| 0.9 | 2.6 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.8 | 2.5 | GO:0006433 | glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433) |
| 0.8 | 9.7 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.8 | 3.1 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.7 | 4.3 | GO:0033132 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.7 | 5.7 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.7 | 2.1 | GO:0060733 | regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264) |
| 0.7 | 2.6 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.6 | 3.2 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.6 | 5.1 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.6 | 3.8 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
| 0.6 | 3.8 | GO:1904674 | positive regulation of somatic stem cell population maintenance(GO:1904674) |
| 0.6 | 1.9 | GO:0060931 | sinoatrial node cell development(GO:0060931) |
| 0.6 | 0.6 | GO:1904815 | negative regulation of protein localization to chromosome, telomeric region(GO:1904815) |
| 0.6 | 1.2 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.6 | 8.4 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.6 | 3.5 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.6 | 2.9 | GO:0071043 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 0.6 | 15.2 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.6 | 4.6 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.6 | 1.7 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
| 0.6 | 1.7 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.6 | 1.7 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 0.5 | 1.6 | GO:0003220 | left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) |
| 0.5 | 6.7 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.5 | 3.9 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.5 | 2.0 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.5 | 2.0 | GO:0036292 | DNA rewinding(GO:0036292) |
| 0.5 | 2.4 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.5 | 1.9 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.5 | 3.2 | GO:0072423 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 0.5 | 4.6 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.5 | 2.3 | GO:0006045 | N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073) |
| 0.4 | 2.1 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.4 | 2.5 | GO:0015878 | biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) |
| 0.4 | 2.1 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.4 | 2.4 | GO:2000288 | positive regulation of myoblast proliferation(GO:2000288) |
| 0.4 | 6.2 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.4 | 1.5 | GO:2000174 | regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 0.4 | 1.9 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.4 | 1.1 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 0.4 | 2.2 | GO:0043504 | mitochondrial DNA repair(GO:0043504) |
| 0.4 | 1.1 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.4 | 1.4 | GO:1903722 | negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722) |
| 0.4 | 3.9 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.3 | 1.4 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.3 | 1.0 | GO:0007387 | anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388) |
| 0.3 | 2.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 0.3 | 3.4 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.3 | 2.3 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.3 | 4.4 | GO:0010838 | positive regulation of keratinocyte proliferation(GO:0010838) |
| 0.3 | 6.8 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.3 | 0.9 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.3 | 2.4 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
| 0.3 | 0.9 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.3 | 0.9 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.3 | 0.9 | GO:0097198 | histone H3-K36 trimethylation(GO:0097198) |
| 0.3 | 1.2 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
| 0.3 | 2.2 | GO:0048549 | endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549) |
| 0.3 | 1.7 | GO:0061624 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.3 | 3.0 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.3 | 8.2 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.3 | 1.4 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.3 | 1.9 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.3 | 1.3 | GO:0048478 | replication fork protection(GO:0048478) |
| 0.3 | 1.8 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.3 | 0.5 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) |
| 0.3 | 31.0 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.3 | 0.5 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.3 | 1.0 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
| 0.2 | 1.2 | GO:1990180 | mitochondrial tRNA 3'-end processing(GO:1990180) |
| 0.2 | 0.7 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.2 | 0.7 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) |
| 0.2 | 4.0 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.2 | 3.7 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.2 | 0.9 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.2 | 1.4 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.2 | 6.2 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.2 | 0.9 | GO:1903381 | neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382) |
| 0.2 | 6.4 | GO:0045005 | DNA-dependent DNA replication maintenance of fidelity(GO:0045005) |
| 0.2 | 1.8 | GO:1901189 | positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.2 | 1.1 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.2 | 3.6 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.2 | 0.9 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.2 | 2.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.2 | 0.6 | GO:0045925 | positive regulation of female receptivity(GO:0045925) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.2 | 1.3 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 0.2 | 1.5 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 0.2 | 2.1 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.2 | 1.5 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.2 | 6.0 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 0.2 | 1.9 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.2 | 0.6 | GO:1903964 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.2 | 1.7 | GO:1903433 | regulation of constitutive secretory pathway(GO:1903433) |
| 0.2 | 0.2 | GO:0006839 | mitochondrial transport(GO:0006839) |
| 0.2 | 0.6 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.2 | 1.6 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.2 | 1.4 | GO:1902741 | interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
| 0.2 | 5.6 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.2 | 6.2 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.2 | 1.2 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.2 | 2.2 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.2 | 1.0 | GO:0035519 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519) |
| 0.2 | 0.6 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.2 | 4.2 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.2 | 0.9 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.2 | 3.5 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 0.2 | 1.1 | GO:0015853 | adenine transport(GO:0015853) |
| 0.2 | 0.7 | GO:0031392 | regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) |
| 0.2 | 0.5 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 0.2 | 0.5 | GO:0006864 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.2 | 0.7 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.2 | 3.6 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.2 | 0.8 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.2 | 2.7 | GO:0021702 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.2 | 1.2 | GO:0033504 | floor plate development(GO:0033504) |
| 0.2 | 0.8 | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.2 | 0.8 | GO:0009257 | 10-formyltetrahydrofolate biosynthetic process(GO:0009257) |
| 0.2 | 7.0 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.2 | 2.7 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 0.2 | 9.0 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.2 | 3.1 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.2 | 2.9 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.2 | 0.5 | GO:0060032 | notochord regression(GO:0060032) |
| 0.2 | 1.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.2 | 1.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.2 | 3.8 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.2 | 10.4 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 1.8 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.1 | 0.9 | GO:0001927 | exocyst assembly(GO:0001927) |
| 0.1 | 0.6 | GO:0048377 | lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) |
| 0.1 | 0.7 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 0.7 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 0.1 | 1.3 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.1 | 1.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 1.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.1 | 0.7 | GO:0031291 | mitotic chromosome movement towards spindle pole(GO:0007079) Ran protein signal transduction(GO:0031291) |
| 0.1 | 1.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.1 | 0.7 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 0.1 | 0.7 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.1 | 1.7 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 0.7 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.1 | 0.3 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.1 | 0.7 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.1 | 1.2 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.1 | 2.8 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 0.8 | GO:0032071 | regulation of endodeoxyribonuclease activity(GO:0032071) |
| 0.1 | 2.5 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.1 | 2.0 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 0.1 | 0.6 | GO:0006896 | Golgi to vacuole transport(GO:0006896) Golgi to lysosome transport(GO:0090160) |
| 0.1 | 0.6 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.1 | 0.5 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.1 | 0.6 | GO:0048319 | mesoderm migration involved in gastrulation(GO:0007509) axial mesoderm morphogenesis(GO:0048319) |
| 0.1 | 0.5 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 0.1 | 0.5 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.1 | 3.8 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 0.1 | 2.2 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
| 0.1 | 0.6 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
| 0.1 | 0.5 | GO:0030311 | poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.1 | 1.0 | GO:0007135 | meiosis II(GO:0007135) |
| 0.1 | 2.2 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.1 | 0.3 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 0.1 | 0.3 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 0.1 | 3.7 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.1 | 0.6 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 0.1 | 0.3 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) |
| 0.1 | 3.7 | GO:0031577 | spindle checkpoint(GO:0031577) |
| 0.1 | 1.9 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.1 | 0.5 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.1 | 1.2 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.1 | 4.6 | GO:2000179 | positive regulation of neural precursor cell proliferation(GO:2000179) |
| 0.1 | 0.7 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.1 | 0.3 | GO:0061760 | antifungal innate immune response(GO:0061760) |
| 0.1 | 0.3 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.1 | 0.3 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
| 0.1 | 0.3 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 2.1 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 0.7 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.1 | 1.4 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.1 | 0.5 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 9.4 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.1 | 1.1 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.1 | 2.6 | GO:0014829 | vascular smooth muscle contraction(GO:0014829) |
| 0.1 | 0.5 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.1 | 0.5 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.1 | 0.7 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.5 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 0.2 | GO:0060979 | vasculogenesis involved in coronary vascular morphogenesis(GO:0060979) |
| 0.1 | 0.5 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
| 0.1 | 1.3 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.1 | 3.9 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.1 | 1.9 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.1 | 0.4 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.1 | 0.5 | GO:0006983 | ER overload response(GO:0006983) |
| 0.1 | 0.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 0.1 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
| 0.1 | 0.8 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.1 | 0.4 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.1 | 0.6 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 0.6 | GO:2000828 | post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 0.1 | 0.8 | GO:0006857 | oligopeptide transport(GO:0006857) |
| 0.1 | 0.1 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.1 | 0.3 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.1 | 0.5 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.1 | 0.4 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.1 | 0.1 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.1 | 2.9 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.1 | 0.3 | GO:1904806 | regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808) |
| 0.1 | 0.6 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.1 | 4.8 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.1 | 0.7 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 0.5 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 1.3 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.1 | 0.3 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 1.8 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 0.4 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.1 | 0.2 | GO:1901895 | negative regulation of calcium-transporting ATPase activity(GO:1901895) |
| 0.1 | 0.8 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.1 | 0.3 | GO:2001270 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.1 | 0.8 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 0.7 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.1 | 2.8 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.1 | 0.5 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.1 | 6.7 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.1 | 1.0 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.1 | 1.1 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 2.6 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 0.8 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.1 | 1.4 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.1 | 0.4 | GO:0071169 | establishment of protein localization to chromatin(GO:0071169) |
| 0.1 | 2.5 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 0.1 | 0.6 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.1 | 5.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 1.1 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 2.4 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 0.1 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 0.0 | 0.4 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.0 | 0.3 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.0 | 1.2 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
| 0.0 | 0.8 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.3 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.0 | 1.7 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.0 | 0.3 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.0 | 0.6 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.7 | GO:1904869 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 0.0 | 0.6 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 0.0 | 1.6 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 2.0 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.6 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 0.2 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 0.0 | 4.3 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 2.9 | GO:0051145 | smooth muscle cell differentiation(GO:0051145) |
| 0.0 | 0.2 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 0.7 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.0 | 0.3 | GO:0072733 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.0 | 1.2 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.0 | 0.9 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 0.2 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 0.0 | 3.5 | GO:0097192 | signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192) |
| 0.0 | 1.0 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.0 | 1.0 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 2.6 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
| 0.0 | 0.1 | GO:0001555 | oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870) |
| 0.0 | 1.1 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.5 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
| 0.0 | 1.8 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 1.6 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
| 0.0 | 0.3 | GO:0002183 | cytoplasmic translational initiation(GO:0002183) |
| 0.0 | 3.2 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.0 | 3.4 | GO:0031110 | regulation of microtubule polymerization or depolymerization(GO:0031110) |
| 0.0 | 0.5 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.0 | 0.2 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.0 | 2.2 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.0 | 0.2 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052) |
| 0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.0 | 0.8 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.0 | 0.9 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 0.0 | 3.9 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 4.8 | GO:0001935 | endothelial cell proliferation(GO:0001935) |
| 0.0 | 1.5 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.0 | 1.1 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.2 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.0 | 1.0 | GO:0010996 | response to auditory stimulus(GO:0010996) |
| 0.0 | 3.0 | GO:0014902 | myotube differentiation(GO:0014902) |
| 0.0 | 0.2 | GO:0007369 | gastrulation(GO:0007369) |
| 0.0 | 0.6 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.2 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
| 0.0 | 1.4 | GO:0046949 | fatty-acyl-CoA biosynthetic process(GO:0046949) |
| 0.0 | 0.2 | GO:0060283 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
| 0.0 | 1.7 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 0.2 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.0 | 0.2 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.0 | 0.2 | GO:0048105 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) |
| 0.0 | 0.2 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 0.0 | 0.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.3 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 0.0 | 2.2 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.0 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.1 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 0.0 | 0.5 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.1 | GO:0016094 | polyprenol biosynthetic process(GO:0016094) |
| 0.0 | 0.1 | GO:0060281 | regulation of oocyte development(GO:0060281) |
| 0.0 | 0.2 | GO:0051561 | positive regulation of mitochondrial calcium ion concentration(GO:0051561) |
| 0.0 | 1.1 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.0 | 0.4 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 0.0 | 0.9 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 5.2 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.0 | 0.1 | GO:0061734 | parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) |
| 0.0 | 0.1 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.0 | 0.9 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.0 | 0.2 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.0 | 0.3 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.0 | 0.1 | GO:0034351 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.0 | 0.1 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.0 | 1.4 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.0 | 0.1 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.0 | 0.1 | GO:0061485 | memory T cell proliferation(GO:0061485) |
| 0.0 | 0.2 | GO:0031498 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) |
| 0.0 | 0.1 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
| 0.0 | 1.2 | GO:0035303 | regulation of dephosphorylation(GO:0035303) |
| 0.0 | 0.4 | GO:0043254 | regulation of protein complex assembly(GO:0043254) |
| 0.0 | 0.6 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.6 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.1 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.0 | 0.6 | GO:0051438 | regulation of ubiquitin-protein transferase activity(GO:0051438) |
| 0.0 | 0.1 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.0 | 0.5 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.1 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.5 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 1.2 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 0.1 | GO:0010446 | response to alkaline pH(GO:0010446) |
| 0.0 | 0.5 | GO:0033146 | regulation of intracellular estrogen receptor signaling pathway(GO:0033146) |
| 0.0 | 0.9 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 2.7 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 0.1 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.0 | 1.5 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
| 0.0 | 0.4 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.0 | 0.1 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 0.3 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 0.5 | GO:0006693 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.0 | 0.6 | GO:0008542 | visual learning(GO:0008542) |
| 0.0 | 0.2 | GO:0048199 | vesicle coating(GO:0006901) vesicle targeting(GO:0006903) vesicle targeting, to, from or within Golgi(GO:0048199) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.0 | 1.9 | GO:0030307 | positive regulation of cell growth(GO:0030307) |
| 0.0 | 0.3 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.0 | 0.0 | GO:1902616 | acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616) |
| 0.0 | 1.1 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.8 | GO:0033762 | response to glucagon(GO:0033762) |
| 0.0 | 1.2 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.3 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.1 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
| 2.3 | 9.3 | GO:1990423 | RZZ complex(GO:1990423) |
| 2.1 | 6.2 | GO:0070685 | macropinocytic cup(GO:0070685) |
| 1.9 | 5.7 | GO:0034455 | t-UTP complex(GO:0034455) |
| 1.9 | 5.6 | GO:0035101 | FACT complex(GO:0035101) |
| 1.5 | 20.1 | GO:0000796 | condensin complex(GO:0000796) |
| 1.3 | 25.1 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 1.1 | 10.3 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 0.9 | 1.8 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.8 | 4.6 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 0.7 | 7.7 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.6 | 1.9 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 0.6 | 1.7 | GO:0097489 | multivesicular body, internal vesicle lumen(GO:0097489) |
| 0.5 | 4.6 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.5 | 1.4 | GO:0009346 | citrate lyase complex(GO:0009346) |
| 0.5 | 1.9 | GO:0031251 | PAN complex(GO:0031251) |
| 0.4 | 1.7 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.4 | 9.6 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.4 | 2.0 | GO:0071942 | XPC complex(GO:0071942) |
| 0.4 | 2.7 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.4 | 3.0 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.4 | 7.1 | GO:0044754 | autolysosome(GO:0044754) |
| 0.3 | 1.3 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 0.3 | 1.9 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.3 | 5.4 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.3 | 0.9 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 0.3 | 4.5 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.3 | 3.4 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.3 | 5.6 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.3 | 1.1 | GO:0032279 | asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280) |
| 0.3 | 2.4 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.3 | 4.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.3 | 5.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.2 | 0.9 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.2 | 1.6 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.2 | 8.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.2 | 6.1 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.2 | 7.8 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.2 | 6.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.2 | 1.3 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.2 | 2.5 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.2 | 0.8 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.2 | 1.9 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.2 | 2.2 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.2 | 1.6 | GO:0031415 | NatA complex(GO:0031415) |
| 0.2 | 1.8 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.2 | 2.9 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.2 | 0.6 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.2 | 3.8 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.2 | 0.7 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.2 | 1.8 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.2 | 9.1 | GO:0016592 | mediator complex(GO:0016592) |
| 0.2 | 8.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.2 | 2.4 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.2 | 0.6 | GO:0031213 | RSF complex(GO:0031213) |
| 0.2 | 0.9 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.1 | 1.6 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 2.4 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 2.0 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 3.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 0.4 | GO:0034657 | GID complex(GO:0034657) |
| 0.1 | 0.5 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.1 | 0.7 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 3.1 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.1 | 0.6 | GO:1990031 | pinceau fiber(GO:1990031) |
| 0.1 | 3.1 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 1.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.1 | 0.5 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.1 | 1.0 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.1 | 4.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 0.3 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.1 | 0.7 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.1 | 1.5 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 1.3 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.1 | 1.8 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 1.5 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 1.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.1 | 1.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 3.3 | GO:0090568 | nuclear transcriptional repressor complex(GO:0090568) |
| 0.1 | 0.6 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 4.8 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 1.0 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 1.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 6.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 0.4 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 16.9 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.1 | 8.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 1.4 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 1.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 11.7 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 0.6 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.1 | 1.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 0.3 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.1 | 7.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 1.5 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 0.3 | GO:0045293 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.1 | 2.9 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.1 | 0.6 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.1 | 13.0 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.1 | 0.6 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.1 | 0.3 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.1 | 3.4 | GO:0044815 | DNA packaging complex(GO:0044815) |
| 0.1 | 2.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 0.7 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.1 | 0.6 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 1.4 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 1.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.2 | GO:1990745 | EARP complex(GO:1990745) |
| 0.0 | 2.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.2 | GO:0032021 | NELF complex(GO:0032021) |
| 0.0 | 0.8 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 2.1 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 3.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 4.0 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.6 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.2 | GO:0060187 | cell pole(GO:0060187) |
| 0.0 | 11.3 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 0.5 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 0.6 | GO:0070187 | telosome(GO:0070187) |
| 0.0 | 0.9 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.4 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 1.4 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.0 | 5.7 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.7 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 0.6 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.1 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 11.4 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 0.6 | GO:1990752 | microtubule end(GO:1990752) |
| 0.0 | 0.3 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 0.2 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.0 | 0.4 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.2 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.0 | 1.4 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.9 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.2 | GO:0016011 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 0.0 | 0.6 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342) |
| 0.0 | 2.4 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 1.2 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.0 | 0.9 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 1.4 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 11.0 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 2.4 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 1.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.5 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.3 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.5 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 1.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.2 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.0 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.0 | 1.1 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.3 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 0.2 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 0.2 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.1 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.0 | 4.9 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 1.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.4 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 3.6 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.7 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 0.1 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.0 | 0.6 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.1 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.6 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 2.0 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 0.1 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.0 | 0.1 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.1 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.0 | 18.1 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 1.8 | 7.2 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 1.8 | 17.8 | GO:0043515 | kinetochore binding(GO:0043515) |
| 1.7 | 5.1 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 1.7 | 5.1 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 1.6 | 6.4 | GO:0036033 | mediator complex binding(GO:0036033) |
| 1.1 | 6.5 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 1.0 | 3.0 | GO:0061663 | NEDD8 ligase activity(GO:0061663) |
| 1.0 | 2.9 | GO:0030626 | U12 snRNA binding(GO:0030626) |
| 0.9 | 2.6 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.8 | 2.5 | GO:0004827 | glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827) |
| 0.8 | 10.8 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.8 | 6.4 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.8 | 3.9 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.8 | 4.6 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 0.6 | 1.7 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
| 0.5 | 1.6 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.5 | 2.0 | GO:0000404 | heteroduplex DNA loop binding(GO:0000404) |
| 0.5 | 1.4 | GO:0003878 | ATP citrate synthase activity(GO:0003878) |
| 0.5 | 1.9 | GO:0033823 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 0.5 | 1.4 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.5 | 3.3 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.5 | 4.6 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.4 | 5.7 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.4 | 8.8 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.4 | 8.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.4 | 1.1 | GO:0070123 | transforming growth factor beta receptor activity, type III(GO:0070123) |
| 0.4 | 3.0 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.4 | 1.9 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.4 | 1.1 | GO:0072510 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.4 | 6.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.3 | 1.7 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.3 | 1.3 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.3 | 1.7 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.3 | 8.1 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.3 | 2.5 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.3 | 2.5 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.3 | 1.2 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
| 0.3 | 12.1 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.3 | 1.2 | GO:0098809 | cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 0.3 | 5.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.3 | 2.9 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.3 | 0.8 | GO:0001147 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.3 | 1.4 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.3 | 0.8 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
| 0.3 | 4.9 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.3 | 2.8 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.3 | 3.3 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) |
| 0.3 | 1.0 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 0.2 | 0.7 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.2 | 0.7 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.2 | 2.6 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.2 | 1.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.2 | 1.4 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.2 | 1.4 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.2 | 0.9 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.2 | 1.8 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.2 | 2.7 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
| 0.2 | 1.1 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.2 | 2.5 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.2 | 1.6 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.2 | 1.0 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.2 | 2.2 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.2 | 0.6 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.2 | 1.7 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.2 | 6.0 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.2 | 0.5 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.2 | 1.3 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.2 | 2.3 | GO:0043199 | sulfate binding(GO:0043199) |
| 0.2 | 2.5 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.2 | 1.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.2 | 0.5 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
| 0.2 | 0.6 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 6.3 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 4.4 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 0.7 | GO:0017089 | glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001) |
| 0.1 | 5.0 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 8.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 0.6 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.1 | 1.5 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 0.8 | GO:0015333 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 0.1 | 5.3 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.1 | 1.8 | GO:0015288 | porin activity(GO:0015288) |
| 0.1 | 1.0 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 11.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 0.5 | GO:0004583 | dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583) |
| 0.1 | 3.1 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 0.9 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.1 | 0.6 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.1 | 3.0 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.1 | 2.0 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 0.8 | GO:0047522 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
| 0.1 | 0.7 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.1 | 0.9 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 0.5 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
| 0.1 | 0.3 | GO:0071208 | histone pre-mRNA stem-loop binding(GO:0071207) histone pre-mRNA DCP binding(GO:0071208) |
| 0.1 | 2.2 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.1 | 4.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 3.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 4.9 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 2.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.3 | GO:0019781 | NEDD8 activating enzyme activity(GO:0019781) |
| 0.1 | 0.7 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.1 | 8.5 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.1 | 2.6 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 15.1 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.8 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.1 | 1.8 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.1 | 4.0 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
| 0.1 | 20.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 3.3 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 2.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 0.5 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 2.6 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.6 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.1 | 3.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.1 | 2.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.7 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.1 | 2.7 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.1 | 0.4 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 0.2 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 0.1 | 4.9 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 0.1 | GO:0004803 | transposase activity(GO:0004803) |
| 0.1 | 0.8 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 0.4 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.1 | 0.3 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.1 | 0.2 | GO:0047536 | 2-aminoadipate transaminase activity(GO:0047536) |
| 0.1 | 0.6 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.1 | 1.3 | GO:0043560 | neurotrophin TRKA receptor binding(GO:0005168) insulin receptor substrate binding(GO:0043560) |
| 0.1 | 2.4 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.1 | 0.4 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 0.5 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.1 | 2.0 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 2.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.6 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.1 | 0.3 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.1 | 2.9 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 0.2 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.1 | 1.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 3.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 0.3 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
| 0.1 | 0.5 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.0 | 1.8 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.1 | GO:0030627 | pre-mRNA 5'-splice site binding(GO:0030627) |
| 0.0 | 4.1 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.8 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 1.6 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.3 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.0 | 0.9 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 1.0 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 1.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 1.0 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 15.0 | GO:0061659 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 0.6 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.0 | 0.5 | GO:0009881 | photoreceptor activity(GO:0009881) |
| 0.0 | 1.6 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 0.6 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 1.0 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 0.9 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 0.2 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.0 | 0.7 | GO:0010181 | FMN binding(GO:0010181) |
| 0.0 | 0.4 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 1.5 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.0 | 2.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.1 | GO:0031628 | opioid peptide activity(GO:0001515) opioid receptor binding(GO:0031628) |
| 0.0 | 0.1 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.0 | 0.3 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 1.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.8 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.1 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.0 | 0.4 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.7 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.1 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.0 | 1.9 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.2 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.0 | 0.3 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.0 | 0.7 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 1.9 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 1.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.1 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.0 | 1.0 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.6 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.1 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.0 | 4.4 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.2 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 0.1 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.0 | 0.5 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 5.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.1 | GO:0002094 | polyprenyltransferase activity(GO:0002094) |
| 0.0 | 0.1 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.0 | 0.4 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
| 0.0 | 0.3 | GO:0008135 | translation factor activity, RNA binding(GO:0008135) |
| 0.0 | 5.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.2 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.0 | 0.8 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.9 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 1.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 1.1 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 12.1 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 1.9 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.9 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.2 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.0 | 0.3 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.1 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.0 | 1.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.4 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.4 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.4 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 0.7 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.4 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.0 | 0.6 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.0 | 1.2 | GO:0009055 | electron carrier activity(GO:0009055) |
| 0.0 | 0.1 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.0 | 0.1 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.0 | 0.2 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.0 | 1.5 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 5.9 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.0 | GO:0015227 | acyl carnitine transmembrane transporter activity(GO:0015227) |
| 0.0 | 0.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 16.3 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.2 | 19.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.2 | 23.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.2 | 2.5 | PID MYC PATHWAY | C-MYC pathway |
| 0.2 | 14.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 8.7 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 24.1 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 9.9 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 4.5 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 5.7 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 6.7 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 14.3 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 2.7 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 1.1 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.1 | 1.3 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 1.6 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 0.9 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 2.3 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.1 | 1.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 4.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 2.7 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 2.7 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 1.0 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 2.9 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 3.1 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 0.9 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 1.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 1.5 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.2 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.4 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.7 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 1.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 1.2 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.5 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 2.9 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.8 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 2.1 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.6 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.4 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.4 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.8 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.4 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.0 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.7 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.3 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.6 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.3 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.5 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 0.9 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 13.8 | REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.4 | 10.8 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.4 | 2.1 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.3 | 11.7 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.3 | 8.3 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.3 | 4.5 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.2 | 4.6 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.2 | 9.7 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.2 | 8.1 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.2 | 3.1 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.2 | 5.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 4.4 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.2 | 2.6 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.2 | 0.3 | REACTOME REGULATION OF APOPTOSIS | Genes involved in Regulation of Apoptosis |
| 0.2 | 5.6 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.2 | 2.1 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.2 | 23.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 8.3 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.2 | 3.3 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 15.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 3.9 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.1 | 10.2 | REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.1 | 0.5 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 0.1 | 6.0 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 3.5 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 3.0 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 2.7 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 6.3 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 3.1 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 7.2 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.1 | 10.2 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.1 | 2.9 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.1 | 1.8 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 1.7 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 10.1 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 1.1 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 2.0 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.1 | 0.3 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 2.7 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 0.5 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 0.6 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.1 | 1.6 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.1 | 2.3 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 0.4 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 2.8 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.0 | 0.6 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 1.4 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 1.8 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 10.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.9 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 0.6 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.0 | 2.8 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 1.8 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 2.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 1.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.6 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.6 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.7 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 1.0 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.4 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.9 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.7 | REACTOME PI3K AKT ACTIVATION | Genes involved in PI3K/AKT activation |
| 0.0 | 0.3 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.0 | 0.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 1.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.7 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 2.0 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.8 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.4 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 0.7 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.9 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.6 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.2 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.3 | REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| 0.0 | 0.9 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 4.7 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 0.3 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |