ISMARA results: ZBTB6

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZBTB6

Z-value: 2.47

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Transcription factors associated with ZBTB6

Gene Symbol	Gene ID	Gene Info
ZBTB6 Ensembl NCBI GeneCards UniProt	ENSG00000186130.4	zinc finger and BTB domain containing 6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZBTB6	hg19_v2_chr9_-_125675576_125675612	-0.89	1.3e-07	Click!

Activity profile of ZBTB6 motif

Sorted Z-values of ZBTB6 motif

No targets for ZBTB6

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.4	5.5	GO:0051710	cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1	5.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	4.9	GO:1901998	toxin transport(GO:1901998)
0.5	3.8	GO:1903575	cornified envelope assembly(GO:1903575)
0.1	3.5	GO:0070977	bone maturation(GO:0070977)
0.0	3.4	GO:0015701	bicarbonate transport(GO:0015701)
0.3	3.2	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1	3.0	GO:0035082	axoneme assembly(GO:0035082)
0.0	3.0	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	2.9	GO:0071294	cellular response to zinc ion(GO:0071294)

Showing 1 to 10 of 286 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	13.5	GO:0045095	keratin filament(GO:0045095)
0.1	6.3	GO:0030131	clathrin adaptor complex(GO:0030131)
0.3	3.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	3.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.3	2.5	GO:0031415	NatA complex(GO:0031415)
0.1	2.4	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	2.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	2.3	GO:0031594	neuromuscular junction(GO:0031594)
0.2	2.1	GO:0072687	meiotic spindle(GO:0072687)
0.1	1.9	GO:0042571	immunoglobulin complex, circulating(GO:0042571)

Showing 1 to 10 of 101 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	11.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	6.4	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3	6.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	3.5	GO:0031489	myosin V binding(GO:0031489)
0.0	3.5	GO:0051082	unfolded protein binding(GO:0051082)
0.1	3.4	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	3.3	GO:0044325	ion channel binding(GO:0044325)
0.0	3.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	2.6	GO:0032794	GTPase activating protein binding(GO:0032794)
0.6	2.5	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)

Showing 1 to 10 of 198 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	4.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	3.0	PID BMP PATHWAY	BMP receptor signaling
0.0	2.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	2.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	2.1	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	1.6	PID FOXO PATHWAY	FoxO family signaling
0.0	1.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms

Showing 1 to 10 of 42 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	3.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	3.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	3.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	3.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	2.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.2	2.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	2.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.7	REACTOME XENOBIOTICS	Genes involved in Xenobiotics

Showing 1 to 10 of 57 entries

Results for ZBTB6

Z-value: 2.47

Motif logo

Transcription factors associated with ZBTB6

Activity-expression correlation:

Activity profile of ZBTB6 motif

Sorted Z-values of ZBTB6 motif

No targets for ZBTB6

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: