ISMARA results: ZBTB7A

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZBTB7A_ZBTB7C

Z-value: 0.63

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Transcription factors associated with ZBTB7A_ZBTB7C

Gene Symbol	Gene ID	Gene Info
ZBTB7A Ensembl NCBI GeneCards UniProt	ENSG00000178951.4	zinc finger and BTB domain containing 7A
ZBTB7C Ensembl NCBI GeneCards UniProt	ENSG00000184828.5	zinc finger and BTB domain containing 7C

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZBTB7C	hg19_v2_chr18_-_45663666_45663732	0.84	3.5e-06	Click!
ZBTB7A	hg19_v2_chr19_-_4066890_4066943	0.68	8.7e-04	Click!

Activity profile of ZBTB7A_ZBTB7C motif

Sorted Z-values of ZBTB7A_ZBTB7C motif

No targets for ZBTB7A_ZBTB7C

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB7A_ZBTB7C

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	2.1	GO:0043587	tongue morphogenesis(GO:0043587)
0.1	1.9	GO:0051546	keratinocyte migration(GO:0051546)
0.2	1.8	GO:0051013	microtubule severing(GO:0051013)
0.4	1.7	GO:0051710	cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.5	1.6	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	1.6	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.0	1.6	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	1.5	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.1	1.3	GO:0090168	Golgi reassembly(GO:0090168)

Showing 1 to 10 of 76 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.9	GO:0045095	keratin filament(GO:0045095)
0.0	3.5	GO:0005882	intermediate filament(GO:0005882)
0.1	2.2	GO:0045180	basal cortex(GO:0045180)
0.0	1.6	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	1.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	1.0	GO:0002102	podosome(GO:0002102)
0.1	0.9	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.6	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.6	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.6	GO:0044295	axonal growth cone(GO:0044295)

Showing 1 to 10 of 33 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.2	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.2	1.8	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	1.8	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	1.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	1.0	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.9	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.9	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.7	GO:0043015	gamma-tubulin binding(GO:0043015)

Showing 1 to 10 of 39 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
1.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.6	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway

Showing 1 to 4 of 4 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.1	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	1.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.1	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.8	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival

Showing 1 to 9 of 9 entries

Results for ZBTB7A_ZBTB7C

Z-value: 0.63

Motif logo

Transcription factors associated with ZBTB7A_ZBTB7C

Activity-expression correlation:

Activity profile of ZBTB7A_ZBTB7C motif

Sorted Z-values of ZBTB7A_ZBTB7C motif

No targets for ZBTB7A_ZBTB7C

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB7A_ZBTB7C

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: