avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ZFHX3 Links Ensembl NCBI GeneCards UniProt	ENSG00000140836.10	zinc finger homeobox 3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZFHX3	hg19_v2_chr16_-_73093597_73093597	0.25	2.9e-01	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.9	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3	1.8	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.3	1.9	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.3	0.8	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2	3.0	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	1.0	GO:0036509	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2	1.9	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.5	GO:2000007	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1	1.8	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.4	GO:0036367	adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1	0.4	GO:0051958	methotrexate transport(GO:0051958)
0.1	0.3	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	1.8	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.2	GO:0061364	negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0	0.1	GO:0009441	glycolate metabolic process(GO:0009441)
0.0	0.8	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.1	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.0	0.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.2	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.1	GO:0046373	arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0	0.2	GO:0040031	snRNA modification(GO:0040031)
0.0	0.5	GO:0035640	exploration behavior(GO:0035640)
0.0	0.1	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.8	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2	1.8	GO:0005579	membrane attack complex(GO:0005579)
0.2	3.0	GO:0005577	fibrinogen complex(GO:0005577)
0.1	1.9	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.5	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0	1.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.8	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.2	GO:0045277	respiratory chain complex IV(GO:0045277)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.9	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.4	1.9	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.3	3.9	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2	0.8	GO:0019770	IgG receptor activity(GO:0019770)
0.1	1.8	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1	0.3	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.1	0.4	GO:0015350	methotrexate transporter activity(GO:0015350)
0.1	1.0	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	1.8	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:1904854	proteasome core complex binding(GO:1904854)
0.0	1.8	GO:0008009	chemokine activity(GO:0008009)
0.0	0.5	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	1.0	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.8	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.5	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.4	GO:0070492	phosphatidylinositol-5-phosphate binding(GO:0010314) oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0	0.1	GO:0046556	alpha-L-arabinofuranosidase activity(GO:0046556)
0.0	0.8	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	1.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.8	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	1.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	3.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.0	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	1.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling