ISMARA results: ZKSCAN3

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZKSCAN3

Z-value: 0.89

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Transcription factors associated with ZKSCAN3

Gene Symbol	Gene ID	Gene Info
ZKSCAN3 Ensembl NCBI GeneCards UniProt	ENSG00000189298.9	zinc finger with KRAB and SCAN domains 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZKSCAN3	hg19_v2_chr6_+_28317685_28317761	-0.48	3.2e-02	Click!

Activity profile of ZKSCAN3 motif

Sorted Z-values of ZKSCAN3 motif

No targets for ZKSCAN3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	3.6	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4	3.6	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.0	1.7	GO:0031055	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	1.4	GO:1901078	negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1	1.4	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	1.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.2	1.3	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	1.1	GO:0002385	mucosal immune response(GO:0002385)
0.0	1.1	GO:0043276	anoikis(GO:0043276)
0.3	1.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)

Showing 1 to 10 of 26 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.6	GO:0032002	interleukin-28 receptor complex(GO:0032002)
0.1	1.7	GO:0010369	chromocenter(GO:0010369)
0.0	1.4	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	1.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	1.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.3	1.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	1.0	GO:0033269	internode region of axon(GO:0033269)
0.0	0.9	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.6	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)

Showing 1 to 10 of 14 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.2	GO:0005125	cytokine activity(GO:0005125)
0.7	3.6	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	1.4	GO:0043015	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) gamma-tubulin binding(GO:0043015)
0.2	1.3	GO:0004359	glutaminase activity(GO:0004359)
0.2	1.1	GO:1990450	linear polyubiquitin binding(GO:1990450)
0.1	1.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.9	GO:0031402	sodium ion binding(GO:0031402)
0.1	0.6	GO:1902122	chenodeoxycholic acid binding(GO:1902122)
0.1	0.6	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)

Showing 1 to 10 of 17 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
1.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway

Showing 1 to 3 of 3 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade

Showing 1 to 7 of 7 entries

Results for ZKSCAN3

Z-value: 0.89

Motif logo

Transcription factors associated with ZKSCAN3

Activity-expression correlation:

Activity profile of ZKSCAN3 motif

Sorted Z-values of ZKSCAN3 motif

No targets for ZKSCAN3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: