ISMARA results: ZNF143

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF143

Z-value: 4.97

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Transcription factors associated with ZNF143

Gene Symbol	Gene ID	Gene Info
ZNF143 Ensembl NCBI GeneCards UniProt	ENSG00000166478.5	zinc finger protein 143

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZNF143	hg19_v2_chr11_+_9482551_9482604	0.57	8.0e-03	Click!

Activity profile of ZNF143 motif

Sorted Z-values of ZNF143 motif

No targets for ZNF143

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF143

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.1	26.5	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
5.8	17.5	GO:0070631	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2	13.4	GO:0042073	intraciliary transport(GO:0042073)
1.3	10.1	GO:1903751	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1	10.0	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
0.3	9.6	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
1.6	9.5	GO:0034421	post-translational protein acetylation(GO:0034421)
0.8	9.1	GO:0010032	meiotic chromosome condensation(GO:0010032)
2.9	8.7	GO:0070510	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
1.2	8.4	GO:0035624	receptor transactivation(GO:0035624)

Showing 1 to 10 of 275 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.3	26.1	GO:0032133	chromosome passenger complex(GO:0032133)
5.8	17.5	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.1	15.1	GO:0005871	kinesin complex(GO:0005871)
0.3	10.1	GO:0071682	endocytic vesicle lumen(GO:0071682)
1.0	9.5	GO:0016012	sarcoglycan complex(GO:0016012)
0.6	9.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	9.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	9.3	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.7	9.1	GO:0000796	condensin complex(GO:0000796)
2.2	8.7	GO:0031436	BRCA1-BARD1 complex(GO:0031436)

Showing 1 to 10 of 151 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	24.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.6	20.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	10.9	GO:0003777	microtubule motor activity(GO:0003777)
0.7	10.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	9.6	GO:0003684	damaged DNA binding(GO:0003684)
1.2	9.5	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.7	8.4	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.0	8.1	GO:0030695	GTPase regulator activity(GO:0030695)
0.2	7.8	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	7.8	GO:0048365	Rac GTPase binding(GO:0048365)

Showing 1 to 10 of 200 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	44.8	PID AURORA B PATHWAY	Aurora B signaling
0.3	27.0	PID FANCONI PATHWAY	Fanconi anemia pathway
0.3	13.1	PID ATR PATHWAY	ATR signaling pathway
0.1	10.6	PID P53 REGULATION PATHWAY	p53 pathway
0.2	7.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	6.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.2	5.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	5.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	5.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	5.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes

Showing 1 to 10 of 40 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	54.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.5	19.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3	12.9	REACTOME KINESINS	Genes involved in Kinesins
0.6	8.9	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.2	8.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	8.6	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	8.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.6	8.3	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.2	7.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	6.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes

Showing 1 to 10 of 68 entries

Results for ZNF143

Z-value: 4.97

Motif logo

Transcription factors associated with ZNF143

Activity-expression correlation:

Activity profile of ZNF143 motif

Sorted Z-values of ZNF143 motif

No targets for ZNF143

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF143

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: