avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ZNF148 Links Ensembl NCBI GeneCards UniProt	ENSG00000163848.14	zinc finger protein 148

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZNF148	hg19_v2_chr3_-_125094093_125094198	0.67	1.3e-03	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	8.7	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.4	7.3	GO:0048597	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
2.1	29.1	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
2.1	8.2	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.9	9.3	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
1.7	5.0	GO:0060697	positive regulation of phospholipid catabolic process(GO:0060697)
1.6	6.4	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
1.6	4.8	GO:2000297	negative regulation of synapse maturation(GO:2000297)
1.6	27.0	GO:0035878	nail development(GO:0035878)
1.5	8.9	GO:0030421	defecation(GO:0030421)
1.4	4.2	GO:0035674	tricarboxylic acid transmembrane transport(GO:0035674)
1.4	8.2	GO:0072752	cellular response to rapamycin(GO:0072752)
1.1	6.6	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.0	7.1	GO:0060600	dichotomous subdivision of an epithelial terminal unit(GO:0060600)
1.0	18.1	GO:0015816	glycine transport(GO:0015816)
1.0	4.9	GO:0042360	vitamin E metabolic process(GO:0042360)
0.9	2.7	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.9	6.0	GO:1902164	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.9	4.3	GO:1904448	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.8	3.4	GO:1904978	regulation of endosome organization(GO:1904978)
0.8	1.6	GO:0048627	myoblast development(GO:0048627)
0.8	2.4	GO:0050904	diapedesis(GO:0050904)
0.8	8.6	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.8	3.0	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.8	3.0	GO:1904499	glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.7	3.0	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.7	8.1	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.7	7.3	GO:1903764	regulation of potassium ion export across plasma membrane(GO:1903764)
0.7	7.6	GO:0031944	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.7	8.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.7	4.0	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.7	4.6	GO:0051012	microtubule sliding(GO:0051012)
0.6	1.9	GO:0033341	regulation of collagen binding(GO:0033341)
0.6	12.5	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.6	8.7	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.6	1.9	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.6	4.3	GO:0006344	optic cup formation involved in camera-type eye development(GO:0003408) maintenance of chromatin silencing(GO:0006344)
0.6	4.2	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.6	17.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.6	1.7	GO:0001300	chronological cell aging(GO:0001300)
0.6	5.7	GO:2000467	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.6	2.2	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.6	1.1	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.5	4.4	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.5	22.9	GO:0006783	heme biosynthetic process(GO:0006783)
0.5	3.0	GO:0097021	lymphocyte migration into lymphoid organs(GO:0097021)
0.5	6.0	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.5	2.8	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.5	1.4	GO:0003249	cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.5	2.7	GO:0035063	nuclear speck organization(GO:0035063)
0.5	3.2	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.5	3.2	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.4	1.3	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.4	1.3	GO:0033488	cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.4	3.9	GO:0072553	terminal button organization(GO:0072553)
0.4	1.3	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
0.4	3.0	GO:0051414	response to cortisol(GO:0051414)
0.4	3.4	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.4	5.9	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.4	5.4	GO:0042048	olfactory behavior(GO:0042048)
0.4	7.6	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.4	3.6	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415)
0.4	1.2	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.4	2.2	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.4	4.7	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.3	1.7	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.3	3.0	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.3	1.0	GO:1904562	phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.3	5.9	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.3	6.4	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.3	4.1	GO:0034201	response to oleic acid(GO:0034201)
0.3	5.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.3	1.5	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.3	4.8	GO:0015693	magnesium ion transport(GO:0015693)
0.3	1.5	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3	1.7	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.3	3.4	GO:0006657	CDP-choline pathway(GO:0006657)
0.3	1.1	GO:0019417	sulfur oxidation(GO:0019417)
0.3	8.1	GO:0016180	snRNA processing(GO:0016180)
0.3	3.7	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3	1.6	GO:0030047	actin modification(GO:0030047)
0.3	2.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	3.9	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2	2.9	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2	2.1	GO:1905232	cellular response to L-glutamate(GO:1905232)
0.2	0.9	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.2	6.7	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.2	1.4	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2	1.5	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.2	0.4	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.2	2.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	2.6	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.2	0.8	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2	1.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.2	2.7	GO:0009414	response to water deprivation(GO:0009414)
0.2	1.9	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2	0.6	GO:0043634	polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.2	8.3	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.2	4.6	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.2	6.1	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
0.2	7.5	GO:0061157	mRNA destabilization(GO:0061157)
0.2	1.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.2	1.4	GO:0045921	positive regulation of exocytosis(GO:0045921)
0.2	1.7	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.2	3.4	GO:0090161	Golgi ribbon formation(GO:0090161)
0.2	6.2	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.2	0.5	GO:0035284	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2	1.6	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	1.5	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	2.1	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1	0.9	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1	1.8	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	1.7	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1	2.0	GO:0072104	glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1	0.8	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	1.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	7.0	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.1	0.9	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.1	1.8	GO:2000291	regulation of myoblast proliferation(GO:2000291)
0.1	1.0	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.1	1.5	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	1.3	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1	2.6	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.6	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.1	1.3	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1	2.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.3	GO:0072616	interleukin-18 secretion(GO:0072616)
0.1	1.2	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.1	0.3	GO:0097359	UDP-glucosylation(GO:0097359)
0.1	0.4	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1	2.5	GO:0051639	actin filament network formation(GO:0051639)
0.1	4.9	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.1	0.4	GO:0035425	autocrine signaling(GO:0035425)
0.1	6.7	GO:0008038	neuron recognition(GO:0008038)
0.1	1.4	GO:0060056	mammary gland involution(GO:0060056)
0.1	4.4	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	1.6	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1	3.3	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	1.6	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	1.0	GO:0034378	chylomicron assembly(GO:0034378)
0.1	2.4	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.9	GO:0006983	ER overload response(GO:0006983)
0.1	0.9	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	5.3	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1	1.5	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1	1.7	GO:0036065	fucosylation(GO:0036065)
0.1	4.5	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.1	0.2	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.1	2.4	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.1	0.6	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.9	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.1	0.6	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1	0.3	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.1	4.3	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	2.1	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1	0.6	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1	0.8	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1	0.8	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	0.6	GO:0060313	negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1	0.6	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.9	GO:0007512	adult heart development(GO:0007512)
0.1	0.8	GO:0034465	response to carbon monoxide(GO:0034465)
0.1	1.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.1	0.2	GO:0010157	response to chlorate(GO:0010157)
0.1	1.9	GO:0021511	spinal cord patterning(GO:0021511)
0.1	0.4	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	1.4	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.2	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1	1.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.1	0.7	GO:0038203	TORC2 signaling(GO:0038203)
0.1	0.5	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	0.5	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1	0.8	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.1	0.9	GO:0014029	neural crest formation(GO:0014029)
0.1	1.3	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.1	1.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.4	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.3	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.1	GO:0050823	peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0	0.2	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.6	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	1.2	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	6.5	GO:0070268	cornification(GO:0070268)
0.0	0.4	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	1.1	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.1	GO:1905203	regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) regulation of connective tissue replacement(GO:1905203) negative regulation of connective tissue replacement(GO:1905204)
0.0	1.2	GO:0044804	nucleophagy(GO:0044804)
0.0	0.5	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.5	GO:0006449	regulation of translational termination(GO:0006449)
0.0	3.4	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.3	GO:0090500	endocardial cushion to mesenchymal transition(GO:0090500)
0.0	2.7	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	1.3	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.0	2.1	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.9	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	1.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0015870	acetylcholine transport(GO:0015870)
0.0	1.4	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.5	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.1	GO:1902725	negative regulation of satellite cell differentiation(GO:1902725)
0.0	1.0	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.8	GO:0033622	integrin activation(GO:0033622)
0.0	0.5	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.2	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	1.9	GO:0097581	lamellipodium organization(GO:0097581)
0.0	3.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	2.5	GO:0030888	regulation of B cell proliferation(GO:0030888)
0.0	2.5	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	1.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	2.7	GO:0000045	autophagosome assembly(GO:0000045)
0.0	1.1	GO:0001662	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0	0.6	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	1.2	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.2	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	1.0	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0	4.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.0	0.6	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.5	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0061056	sclerotome development(GO:0061056)
0.0	1.8	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.4	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.0	0.4	GO:0006363	transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0	0.6	GO:0040029	regulation of gene expression, epigenetic(GO:0040029)
0.0	0.3	GO:0034776	response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0	0.4	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	1.6	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	4.8	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.9	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0045402	interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0	2.5	GO:0043543	protein acylation(GO:0043543)
0.0	0.2	GO:0030252	growth hormone secretion(GO:0030252)
0.0	1.1	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	1.5	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	1.2	GO:0007004	telomere maintenance via telomerase(GO:0007004)
0.0	1.2	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	1.3	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.1	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228) synaptic transmission, GABAergic(GO:0051932)
0.0	1.2	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.7	GO:0010501	RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.7	27.0	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
2.6	10.6	GO:0005607	laminin-2 complex(GO:0005607)
1.1	5.7	GO:0071942	XPC complex(GO:0071942)
0.9	4.3	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.6	6.7	GO:0005610	laminin-5 complex(GO:0005610)
0.5	8.2	GO:0001520	outer dense fiber(GO:0001520)
0.5	7.6	GO:0042587	glycogen granule(GO:0042587)
0.5	7.3	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.5	8.2	GO:0031931	TORC1 complex(GO:0031931)
0.5	3.0	GO:1990584	cardiac Troponin complex(GO:1990584)
0.5	2.5	GO:0034753	nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.5	2.4	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.5	7.4	GO:0032039	integrator complex(GO:0032039)
0.5	7.3	GO:0097025	lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.4	1.3	GO:0016600	flotillin complex(GO:0016600)
0.4	4.1	GO:0016589	NURF complex(GO:0016589)
0.4	3.0	GO:0070369	Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.4	1.8	GO:1990425	ryanodine receptor complex(GO:1990425)
0.3	8.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.3	7.6	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3	1.4	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.3	1.5	GO:0005726	perichromatin fibrils(GO:0005726)
0.2	1.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2	2.6	GO:0000439	core TFIIH complex(GO:0000439)
0.2	3.6	GO:0032426	stereocilium tip(GO:0032426)
0.2	6.0	GO:0005922	connexon complex(GO:0005922)
0.2	6.0	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	7.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	2.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2	6.1	GO:0005614	interstitial matrix(GO:0005614)
0.2	2.8	GO:0005921	gap junction(GO:0005921)
0.2	0.5	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.2	0.6	GO:0031084	BLOC-2 complex(GO:0031084)
0.2	1.2	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	1.5	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	0.6	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.1	13.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	1.5	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	5.6	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	10.1	GO:0001533	cornified envelope(GO:0001533)
0.1	1.5	GO:0005916	fascia adherens(GO:0005916)
0.1	3.8	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	3.5	GO:0071564	npBAF complex(GO:0071564)
0.1	1.5	GO:0016342	catenin complex(GO:0016342)
0.1	4.8	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	1.2	GO:0008091	spectrin(GO:0008091)
0.1	15.2	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	8.9	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	1.7	GO:0048786	presynaptic active zone(GO:0048786)
0.1	0.8	GO:0071203	WASH complex(GO:0071203)
0.1	1.9	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	2.2	GO:0000346	transcription export complex(GO:0000346)
0.1	4.9	GO:0032420	stereocilium(GO:0032420)
0.1	1.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	2.8	GO:0070822	Sin3-type complex(GO:0070822)
0.1	2.9	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.4	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.1	9.2	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	1.5	GO:0030914	STAGA complex(GO:0030914)
0.1	0.5	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	3.0	GO:0071437	invadopodium(GO:0071437)
0.1	4.8	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	0.4	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	2.7	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.1	0.6	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	4.6	GO:0002102	podosome(GO:0002102)
0.1	1.0	GO:0030008	TRAPP complex(GO:0030008)
0.1	8.7	GO:0005796	Golgi lumen(GO:0005796)
0.1	1.5	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	2.7	GO:0030118	clathrin coat(GO:0030118)
0.1	2.2	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1	1.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.6	GO:0005677	chromatin silencing complex(GO:0005677)
0.1	0.9	GO:0097427	microtubule bundle(GO:0097427)
0.1	6.7	GO:0070469	respiratory chain(GO:0070469)
0.1	1.4	GO:0031045	dense core granule(GO:0031045)
0.0	2.7	GO:0043034	costamere(GO:0043034)
0.0	5.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.4	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.8	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	2.5	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0060187	cell pole(GO:0060187)
0.0	1.1	GO:0046930	pore complex(GO:0046930)
0.0	0.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	3.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	1.0	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	5.6	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	5.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.7	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.4	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.6	GO:0033391	chromatoid body(GO:0033391)
0.0	0.3	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.7	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	4.1	GO:0005604	basement membrane(GO:0005604)
0.0	0.7	GO:0005686	U2 snRNP(GO:0005686)
0.0	1.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	4.4	GO:0032432	actin filament bundle(GO:0032432)
0.0	1.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.3	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.5	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	2.0	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.4	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.9	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	3.1	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.4	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	2.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	3.8	GO:0031902	late endosome membrane(GO:0031902)
0.0	4.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	1.9	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	1.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	5.0	GO:0001726	ruffle(GO:0001726)
0.0	6.6	GO:0000790	nuclear chromatin(GO:0000790)
0.0	1.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	25.0	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	1.1	GO:0005795	Golgi stack(GO:0005795)
0.0	0.9	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.0	3.2	GO:0000785	chromatin(GO:0000785)
0.0	5.6	GO:0016607	nuclear speck(GO:0016607)
0.0	0.9	GO:0030529	intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0	0.1	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.8	GO:0045171	intercellular bridge(GO:0045171)
0.0	2.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0042641	actomyosin(GO:0042641)
0.0	0.9	GO:0005741	mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0	1.4	GO:0043204	perikaryon(GO:0043204)
0.0	11.3	GO:0005730	nucleolus(GO:0005730)
0.0	0.7	GO:0045095	keratin filament(GO:0045095)
0.0	0.3	GO:1902711	GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	27.0	GO:0038132	neuregulin binding(GO:0038132)
1.5	7.6	GO:0050115	myosin-light-chain-phosphatase activity(GO:0050115)
1.4	4.3	GO:1990698	palmitoleoyltransferase activity(GO:1990698)
1.3	6.7	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
1.2	5.0	GO:0004461	lactose synthase activity(GO:0004461)
1.2	18.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
1.2	27.6	GO:0045499	chemorepellent activity(GO:0045499)
0.9	2.7	GO:0008841	tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.9	4.3	GO:0003867	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.8	3.4	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.7	3.0	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.7	5.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.7	4.2	GO:0017153	citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.7	2.1	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.6	14.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.6	2.5	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.6	1.8	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.6	3.4	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6	7.3	GO:0097016	L27 domain binding(GO:0097016)
0.6	2.2	GO:0098808	mRNA cap binding(GO:0098808)
0.5	3.9	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.5	9.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.4	1.3	GO:0008398	sterol 14-demethylase activity(GO:0008398)
0.4	7.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.4	5.9	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4	5.5	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.4	1.2	GO:0004108	citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.4	7.6	GO:1990239	steroid hormone binding(GO:1990239)
0.4	8.2	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.4	2.2	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.4	3.0	GO:0030172	troponin C binding(GO:0030172)
0.4	2.5	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.3	5.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3	4.5	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.3	1.7	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.3	6.4	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.3	8.7	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.3	5.0	GO:0045159	myosin II binding(GO:0045159)
0.3	7.3	GO:0051400	BH domain binding(GO:0051400)
0.3	1.3	GO:0015616	DNA translocase activity(GO:0015616)
0.3	1.8	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.3	8.6	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.3	2.4	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.3	20.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	0.7	GO:1990254	keratin filament binding(GO:1990254)
0.2	9.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	1.7	GO:0098821	BMP receptor activity(GO:0098821)
0.2	2.4	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2	10.6	GO:0001671	ATPase activator activity(GO:0001671)
0.2	1.5	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.2	1.9	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2	2.9	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2	1.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.2	1.2	GO:0019776	Atg8 ligase activity(GO:0019776)
0.2	4.8	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.2	2.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2	1.5	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2	0.8	GO:0005011	macrophage colony-stimulating factor receptor activity(GO:0005011)
0.2	1.1	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2	0.8	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	4.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	7.5	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.6	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1	4.8	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	7.9	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	1.5	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1	4.3	GO:0031491	nucleosome binding(GO:0031491)
0.1	2.8	GO:0005522	profilin binding(GO:0005522)
0.1	1.7	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.4	GO:0051538	iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1	2.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	3.3	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.6	GO:0034584	piRNA binding(GO:0034584)
0.1	5.7	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	1.3	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	1.0	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	3.0	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.3	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1	12.5	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	0.4	GO:0008506	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1	1.3	GO:1901612	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1	2.2	GO:0044548	S100 protein binding(GO:0044548)
0.1	25.9	GO:0008083	growth factor activity(GO:0008083)
0.1	1.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	2.6	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	3.7	GO:0017166	vinculin binding(GO:0017166)
0.1	5.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.1	2.5	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	27.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.6	GO:0043532	angiostatin binding(GO:0043532)
0.1	12.1	GO:0051087	chaperone binding(GO:0051087)
0.1	9.0	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1	0.8	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	1.2	GO:0035198	miRNA binding(GO:0035198)
0.1	12.6	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.1	2.1	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	1.1	GO:0015288	porin activity(GO:0015288)
0.1	1.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	1.6	GO:0017022	myosin binding(GO:0017022)
0.1	2.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	3.1	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	1.7	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1	2.1	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	1.0	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	0.8	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	0.6	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	1.4	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	0.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.9	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	2.4	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.5	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	0.6	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	3.9	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	1.2	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	1.1	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	0.6	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.1	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.2	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	7.4	GO:0005178	integrin binding(GO:0005178)
0.0	1.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	1.0	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	3.6	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	1.0	GO:0031005	filamin binding(GO:0031005)
0.0	2.9	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	1.9	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	1.2	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	1.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.3	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.2	GO:0005119	smoothened binding(GO:0005119)
0.0	3.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	1.7	GO:0032452	histone demethylase activity(GO:0032452)
0.0	3.7	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	2.4	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	1.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.3	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	8.6	GO:0051015	actin filament binding(GO:0051015)
0.0	0.4	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	4.4	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0	0.1	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.0	4.5	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	1.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	1.6	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	3.9	GO:0008201	heparin binding(GO:0008201)
0.0	1.4	GO:0001047	core promoter binding(GO:0001047)
0.0	2.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	2.4	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	3.6	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.0	0.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.7	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	1.1	GO:0050699	WW domain binding(GO:0050699)
0.0	8.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	2.3	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.7	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	1.9	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	4.1	GO:0061630	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	3.9	GO:0030246	carbohydrate binding(GO:0030246)
0.0	6.3	GO:0005525	GTP binding(GO:0005525)
0.0	0.3	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.6	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	44.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.3	7.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	59.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2	14.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	7.1	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	8.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	1.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	3.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	9.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	5.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	3.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	4.0	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	2.6	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	2.4	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	6.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	10.9	PID CDC42 PATHWAY	CDC42 signaling events
0.1	4.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	3.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	7.6	PID PLK1 PATHWAY	PLK1 signaling events
0.1	3.6	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	7.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	1.6	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	30.3	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	0.8	PID EPO PATHWAY	EPO signaling pathway
0.1	9.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	2.5	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.1	2.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.8	PID ALK2 PATHWAY	ALK2 signaling events
0.0	2.5	PID ATM PATHWAY	ATM pathway
0.0	8.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	2.8	PID LKB1 PATHWAY	LKB1 signaling events
0.0	4.1	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	2.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.8	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.9	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	3.4	PID P73PATHWAY	p73 transcription factor network
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.0	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	1.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	7.1	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	2.0	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.5	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.4	PID RHOA REG PATHWAY	Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	8.8	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4	5.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3	8.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.3	7.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	6.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	6.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.2	8.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.2	6.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.2	9.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	5.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	4.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	2.0	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	4.9	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	9.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	6.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.2	8.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2	10.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	5.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	3.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	8.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	2.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	4.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	5.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	17.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	2.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	4.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	9.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	2.5	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	2.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.7	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	4.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	4.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.8	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	1.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	2.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	1.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	2.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	2.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	1.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	1.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	2.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	1.3	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	0.8	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	2.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	3.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.7	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	2.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	1.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	3.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	9.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	1.8	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	2.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	4.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	2.6	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	8.4	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	1.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.9	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.2	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation