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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF148

Z-value: 3.71

Motif logo

Transcription factors associated with ZNF148

Gene Symbol Gene ID Gene Info
ENSG00000163848.14 zinc finger protein 148

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF148hg19_v2_chr3_-_125094093_1250941980.671.3e-03Click!

Activity profile of ZNF148 motif

Sorted Z-values of ZNF148 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF148

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.4 7.3 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
2.1 29.1 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
2.1 8.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.9 9.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.7 5.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
1.6 6.4 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
1.6 4.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.6 27.0 GO:0035878 nail development(GO:0035878)
1.5 8.9 GO:0030421 defecation(GO:0030421)
1.4 4.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
1.4 8.2 GO:0072752 cellular response to rapamycin(GO:0072752)
1.1 6.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.0 7.1 GO:0060600 dichotomous subdivision of an epithelial terminal unit(GO:0060600)
1.0 18.1 GO:0015816 glycine transport(GO:0015816)
1.0 4.9 GO:0042360 vitamin E metabolic process(GO:0042360)
0.9 2.7 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.9 6.0 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.9 4.3 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.8 3.4 GO:1904978 regulation of endosome organization(GO:1904978)
0.8 1.6 GO:0048627 myoblast development(GO:0048627)
0.8 2.4 GO:0050904 diapedesis(GO:0050904)
0.8 8.6 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.8 3.0 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.8 3.0 GO:1904499 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.7 3.0 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.7 8.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.7 7.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.7 7.6 GO:0031944 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.7 8.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.7 4.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.7 4.6 GO:0051012 microtubule sliding(GO:0051012)
0.6 1.9 GO:0033341 regulation of collagen binding(GO:0033341)
0.6 12.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.6 8.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.6 1.9 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.6 4.3 GO:0006344 optic cup formation involved in camera-type eye development(GO:0003408) maintenance of chromatin silencing(GO:0006344)
0.6 4.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.6 17.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 1.7 GO:0001300 chronological cell aging(GO:0001300)
0.6 5.7 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.6 2.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.6 1.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.5 4.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.5 22.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.5 3.0 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.5 6.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.5 2.8 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.5 1.4 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.5 2.7 GO:0035063 nuclear speck organization(GO:0035063)
0.5 3.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.5 3.2 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.4 1.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.4 1.3 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.4 3.9 GO:0072553 terminal button organization(GO:0072553)
0.4 1.3 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
0.4 3.0 GO:0051414 response to cortisol(GO:0051414)
0.4 3.4 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.4 5.9 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 5.4 GO:0042048 olfactory behavior(GO:0042048)
0.4 7.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 3.6 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415)
0.4 1.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.4 2.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.4 4.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 1.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 3.0 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.3 1.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.3 5.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 6.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 4.1 GO:0034201 response to oleic acid(GO:0034201)
0.3 5.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.3 1.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 4.8 GO:0015693 magnesium ion transport(GO:0015693)
0.3 1.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 1.7 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.3 3.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.3 1.1 GO:0019417 sulfur oxidation(GO:0019417)
0.3 8.1 GO:0016180 snRNA processing(GO:0016180)
0.3 3.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 1.6 GO:0030047 actin modification(GO:0030047)
0.3 2.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 3.9 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2 2.9 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 2.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.2 0.9 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 6.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 1.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 1.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.2 2.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 2.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.8 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 1.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 2.7 GO:0009414 response to water deprivation(GO:0009414)
0.2 1.9 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 0.6 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.2 8.3 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.2 4.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 6.1 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.2 7.5 GO:0061157 mRNA destabilization(GO:0061157)
0.2 1.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 1.4 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.2 1.7 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.2 3.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 6.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.2 0.5 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 2.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.9 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 1.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.7 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 2.0 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 7.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.9 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.8 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 1.0 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 1.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 2.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.6 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.1 1.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 2.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:0072616 interleukin-18 secretion(GO:0072616)
0.1 1.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.3 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.4 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 2.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 4.9 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 6.7 GO:0008038 neuron recognition(GO:0008038)
0.1 1.4 GO:0060056 mammary gland involution(GO:0060056)
0.1 4.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 1.6 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 3.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0034378 chylomicron assembly(GO:0034378)
0.1 2.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.9 GO:0006983 ER overload response(GO:0006983)
0.1 0.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 5.3 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 1.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 1.7 GO:0036065 fucosylation(GO:0036065)
0.1 4.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 2.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.9 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 4.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 2.1 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1 0.6 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.6 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.9 GO:0007512 adult heart development(GO:0007512)
0.1 0.8 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 1.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.2 GO:0010157 response to chlorate(GO:0010157)
0.1 1.9 GO:0021511 spinal cord patterning(GO:0021511)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 1.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.2 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 1.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.8 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.1 0.9 GO:0014029 neural crest formation(GO:0014029)
0.1 1.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 1.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.1 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.6 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 1.2 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 6.5 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 1.1 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:1905203 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) regulation of connective tissue replacement(GO:1905203) negative regulation of connective tissue replacement(GO:1905204)
0.0 1.2 GO:0044804 nucleophagy(GO:0044804)
0.0 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.5 GO:0006449 regulation of translational termination(GO:0006449)
0.0 3.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.3 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.0 2.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 2.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 1.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.5 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 1.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.8 GO:0033622 integrin activation(GO:0033622)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 1.9 GO:0097581 lamellipodium organization(GO:0097581)
0.0 3.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 2.5 GO:0030888 regulation of B cell proliferation(GO:0030888)
0.0 2.5 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 1.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 2.7 GO:0000045 autophagosome assembly(GO:0000045)
0.0 1.1 GO:0001662 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 1.0 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 4.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 1.8 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.4 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.6 GO:0040029 regulation of gene expression, epigenetic(GO:0040029)
0.0 0.3 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 4.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.9 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0045402 interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 2.5 GO:0043543 protein acylation(GO:0043543)
0.0 0.2 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 1.2 GO:0007004 telomere maintenance via telomerase(GO:0007004)
0.0 1.2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 1.3 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228) synaptic transmission, GABAergic(GO:0051932)
0.0 1.2 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 27.0 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
2.6 10.6 GO:0005607 laminin-2 complex(GO:0005607)
1.1 5.7 GO:0071942 XPC complex(GO:0071942)
0.9 4.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.6 6.7 GO:0005610 laminin-5 complex(GO:0005610)
0.5 8.2 GO:0001520 outer dense fiber(GO:0001520)
0.5 7.6 GO:0042587 glycogen granule(GO:0042587)
0.5 7.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 8.2 GO:0031931 TORC1 complex(GO:0031931)
0.5 3.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.5 2.5 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.5 2.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.5 7.4 GO:0032039 integrator complex(GO:0032039)
0.5 7.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.4 1.3 GO:0016600 flotillin complex(GO:0016600)
0.4 4.1 GO:0016589 NURF complex(GO:0016589)
0.4 3.0 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.4 1.8 GO:1990425 ryanodine receptor complex(GO:1990425)
0.3 8.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 7.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 1.4 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.3 1.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 1.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 2.6 GO:0000439 core TFIIH complex(GO:0000439)
0.2 3.6 GO:0032426 stereocilium tip(GO:0032426)
0.2 6.0 GO:0005922 connexon complex(GO:0005922)
0.2 6.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 7.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 2.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 6.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.8 GO:0005921 gap junction(GO:0005921)
0.2 0.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 1.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 1.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 13.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 5.6 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 10.1 GO:0001533 cornified envelope(GO:0001533)
0.1 1.5 GO:0005916 fascia adherens(GO:0005916)
0.1 3.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 3.5 GO:0071564 npBAF complex(GO:0071564)
0.1 1.5 GO:0016342 catenin complex(GO:0016342)
0.1 4.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.2 GO:0008091 spectrin(GO:0008091)
0.1 15.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 8.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.8 GO:0071203 WASH complex(GO:0071203)
0.1 1.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 2.2 GO:0000346 transcription export complex(GO:0000346)
0.1 4.9 GO:0032420 stereocilium(GO:0032420)
0.1 1.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 2.8 GO:0070822 Sin3-type complex(GO:0070822)
0.1 2.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 9.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.5 GO:0030914 STAGA complex(GO:0030914)
0.1 0.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 3.0 GO:0071437 invadopodium(GO:0071437)
0.1 4.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 2.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.6 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 4.6 GO:0002102 podosome(GO:0002102)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 8.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 2.7 GO:0030118 clathrin coat(GO:0030118)
0.1 2.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.1 6.7 GO:0070469 respiratory chain(GO:0070469)
0.1 1.4 GO:0031045 dense core granule(GO:0031045)
0.0 2.7 GO:0043034 costamere(GO:0043034)
0.0 5.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 2.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 1.1 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 3.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 5.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 5.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 4.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 4.4 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 3.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 3.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 4.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 1.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 5.0 GO:0001726 ruffle(GO:0001726)
0.0 6.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 25.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 3.2 GO:0000785 chromatin(GO:0000785)
0.0 5.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.9 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 11.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 27.0 GO:0038132 neuregulin binding(GO:0038132)
1.5 7.6 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
1.4 4.3 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
1.3 6.7 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
1.2 5.0 GO:0004461 lactose synthase activity(GO:0004461)
1.2 18.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.2 27.6 GO:0045499 chemorepellent activity(GO:0045499)
0.9 2.7 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.9 4.3 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.8 3.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.7 3.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.7 5.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.7 4.2 GO:0017153 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.7 2.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.6 14.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.6 2.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.6 1.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.6 3.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6 7.3 GO:0097016 L27 domain binding(GO:0097016)
0.6 2.2 GO:0098808 mRNA cap binding(GO:0098808)
0.5 3.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.5 9.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 1.3 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.4 7.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 5.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 5.5 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.4 1.2 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.4 7.6 GO:1990239 steroid hormone binding(GO:1990239)
0.4 8.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.4 2.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.4 3.0 GO:0030172 troponin C binding(GO:0030172)
0.4 2.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 5.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 4.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 1.7 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.3 6.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 8.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 5.0 GO:0045159 myosin II binding(GO:0045159)
0.3 7.3 GO:0051400 BH domain binding(GO:0051400)
0.3 1.3 GO:0015616 DNA translocase activity(GO:0015616)
0.3 1.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 8.6 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.3 2.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 20.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 0.7 GO:1990254 keratin filament binding(GO:1990254)
0.2 9.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.7 GO:0098821 BMP receptor activity(GO:0098821)
0.2 2.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 10.6 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 2.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 4.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 2.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 1.5 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 0.8 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.2 1.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 4.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 7.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.6 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 4.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 7.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 4.3 GO:0031491 nucleosome binding(GO:0031491)
0.1 2.8 GO:0005522 profilin binding(GO:0005522)
0.1 1.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.4 GO:0051538 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 2.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 3.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.6 GO:0034584 piRNA binding(GO:0034584)
0.1 5.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 3.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 12.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.4 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.3 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 2.2 GO:0044548 S100 protein binding(GO:0044548)
0.1 25.9 GO:0008083 growth factor activity(GO:0008083)
0.1 1.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 3.7 GO:0017166 vinculin binding(GO:0017166)
0.1 5.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 27.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 12.1 GO:0051087 chaperone binding(GO:0051087)
0.1 9.0 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.2 GO:0035198 miRNA binding(GO:0035198)
0.1 12.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.1 GO:0015288 porin activity(GO:0015288)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0017022 myosin binding(GO:0017022)
0.1 2.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.6 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 1.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 3.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 7.4 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 3.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 2.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 1.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 3.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 3.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 2.4 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 8.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 4.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 4.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 1.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.9 GO:0008201 heparin binding(GO:0008201)
0.0 1.4 GO:0001047 core promoter binding(GO:0001047)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 3.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 8.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 2.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 4.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 3.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 6.3 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 44.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 7.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 59.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 14.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 7.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 8.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 3.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 9.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 5.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 2.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 6.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 10.9 PID CDC42 PATHWAY CDC42 signaling events
0.1 4.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 3.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 7.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 7.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 30.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 0.8 PID EPO PATHWAY EPO signaling pathway
0.1 9.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.5 PID ATM PATHWAY ATM pathway
0.0 8.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 4.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.8 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 3.4 PID P73PATHWAY p73 transcription factor network
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 7.1 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4 5.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3 8.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 7.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 6.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 6.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 8.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 6.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 9.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 5.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 4.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 4.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 9.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 6.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 8.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 10.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 5.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 8.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 2.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 4.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 5.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 17.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 9.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 4.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 2.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.3 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 3.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 3.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 9.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 4.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 8.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation