ISMARA results: ZNF263

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF263

Z-value: 4.44

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Transcription factors associated with ZNF263

Gene Symbol	Gene ID	Gene Info
ZNF263 Ensembl NCBI GeneCards UniProt	ENSG00000006194.6	zinc finger protein 263

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZNF263	hg19_v2_chr16_+_3333443_3333545	-0.64	2.6e-03	Click!

Activity profile of ZNF263 motif

Sorted Z-values of ZNF263 motif

No targets for ZNF263

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF263

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	22.7	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
2.0	21.8	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
2.7	18.9	GO:0031642	negative regulation of myelination(GO:0031642)
1.5	18.5	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
5.8	17.4	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6	16.8	GO:0030502	negative regulation of bone mineralization(GO:0030502)
2.7	16.5	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.9	16.5	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
3.9	15.4	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.6	14.9	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)

Showing 1 to 10 of 440 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	28.4	GO:0000790	nuclear chromatin(GO:0000790)
0.0	25.6	GO:0016604	nuclear body(GO:0016604)
0.2	25.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
1.1	19.5	GO:0031089	platelet dense granule lumen(GO:0031089)
0.2	19.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
1.5	18.5	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
2.2	17.3	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.1	17.1	GO:0005796	Golgi lumen(GO:0005796)
0.1	16.7	GO:0005923	bicellular tight junction(GO:0005923)
2.4	16.5	GO:0097209	epidermal lamellar body(GO:0097209)

Showing 1 to 10 of 172 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	39.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.1	25.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
2.3	23.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	21.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3	19.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
2.4	16.7	GO:0005134	interleukin-2 receptor binding(GO:0005134)
1.1	16.5	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2	15.5	GO:0002039	p53 binding(GO:0002039)
0.4	15.3	GO:0004707	MAP kinase activity(GO:0004707)
0.3	15.1	GO:0004385	guanylate kinase activity(GO:0004385)

Showing 1 to 10 of 269 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	52.9	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.4	30.0	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.5	16.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.2	16.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.6	15.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	14.3	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.5	12.7	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.2	11.6	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.4	11.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	10.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression

Showing 1 to 10 of 70 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	34.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.6	31.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2	19.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.7	16.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7	15.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	14.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	12.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	12.3	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.3	12.1	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.3	10.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Showing 1 to 10 of 87 entries

Results for ZNF263

Z-value: 4.44

Motif logo

Transcription factors associated with ZNF263

Activity-expression correlation:

Activity profile of ZNF263 motif

Sorted Z-values of ZNF263 motif

No targets for ZNF263

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF263

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: