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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF263

Z-value: 4.44

Motif logo

Transcription factors associated with ZNF263

Gene Symbol Gene ID Gene Info
ENSG00000006194.6 zinc finger protein 263

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF263hg19_v2_chr16_+_3333443_3333545-0.642.6e-03Click!

Activity profile of ZNF263 motif

Sorted Z-values of ZNF263 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF263

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
4.8 14.5 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
3.9 15.4 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
3.4 13.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
2.8 8.3 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
2.7 16.5 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
2.7 18.9 GO:0031642 negative regulation of myelination(GO:0031642)
2.7 8.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
2.1 14.7 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
2.0 21.8 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
1.8 5.5 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
1.7 5.2 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
1.5 18.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
1.5 7.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.3 1.3 GO:0003197 endocardial cushion development(GO:0003197)
1.2 6.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
1.2 3.5 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
1.1 4.3 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
1.0 10.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.0 5.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.0 3.0 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
1.0 6.9 GO:0071461 cellular response to redox state(GO:0071461)
1.0 4.9 GO:0032474 otolith morphogenesis(GO:0032474)
1.0 3.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
1.0 4.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.9 3.7 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.9 2.6 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.9 16.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.8 10.1 GO:0021759 globus pallidus development(GO:0021759)
0.8 3.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.8 2.5 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.8 4.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.8 9.8 GO:0048102 autophagic cell death(GO:0048102)
0.8 3.8 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.8 12.9 GO:0002934 desmosome organization(GO:0002934)
0.8 2.3 GO:0001172 transcription, RNA-templated(GO:0001172)
0.8 3.8 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.7 2.1 GO:0061010 gall bladder development(GO:0061010)
0.7 5.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.7 2.1 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.7 22.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.7 4.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.7 6.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.7 3.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.7 2.0 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.6 2.5 GO:0018277 protein deamination(GO:0018277)
0.6 4.4 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.6 3.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.6 14.9 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.6 16.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.6 1.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.6 6.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.6 3.0 GO:0060214 endocardium formation(GO:0060214)
0.6 5.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.6 1.7 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.6 3.9 GO:0048706 embryonic skeletal system development(GO:0048706)
0.6 1.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.5 2.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.5 1.1 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.5 4.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 1.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.5 3.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.5 6.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.5 0.5 GO:0035878 nail development(GO:0035878)
0.5 1.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.5 3.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 6.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.5 0.5 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662)
0.5 2.8 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.5 7.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.5 2.3 GO:2000503 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.5 4.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.5 2.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.4 11.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.4 3.1 GO:0006196 AMP catabolic process(GO:0006196)
0.4 3.0 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.4 0.4 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.4 3.9 GO:0001661 conditioned taste aversion(GO:0001661)
0.4 0.9 GO:2000683 regulation of cellular response to X-ray(GO:2000683)
0.4 1.7 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.4 2.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.4 2.0 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.4 8.4 GO:0016540 protein autoprocessing(GO:0016540)
0.4 2.4 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4 7.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.4 4.7 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.4 1.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.4 2.9 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.4 5.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.4 5.4 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.4 1.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.4 2.5 GO:0060992 response to fungicide(GO:0060992)
0.4 3.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 1.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.3 2.8 GO:0032439 endosome localization(GO:0032439)
0.3 0.3 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.3 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.3 2.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.3 1.0 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.3 1.0 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.3 1.0 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.3 1.0 GO:0098906 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.3 1.9 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.3 1.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.3 0.9 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.3 1.9 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3 8.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 11.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 3.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 0.9 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.3 1.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3 1.1 GO:0060166 olfactory pit development(GO:0060166)
0.3 3.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.3 1.7 GO:0072752 cellular response to rapamycin(GO:0072752)
0.3 1.7 GO:0090527 actin filament reorganization(GO:0090527)
0.3 3.6 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.3 3.6 GO:0060056 mammary gland involution(GO:0060056)
0.3 1.9 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.3 4.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.3 1.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 1.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 1.6 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090101)
0.3 3.7 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.3 1.8 GO:0051012 microtubule sliding(GO:0051012)
0.3 0.8 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.2 3.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 1.5 GO:0044805 late nucleophagy(GO:0044805)
0.2 3.0 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.5 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2 1.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.2 1.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.2 1.4 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.2 2.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 3.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 1.8 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 1.1 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.2 1.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 5.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 2.9 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 2.9 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.2 0.9 GO:0048839 inner ear development(GO:0048839)
0.2 1.8 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 1.3 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.6 GO:0015680 intracellular copper ion transport(GO:0015680)
0.2 3.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 1.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 0.8 GO:0061198 fungiform papilla formation(GO:0061198)
0.2 1.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 1.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.2 1.2 GO:0030100 regulation of endocytosis(GO:0030100)
0.2 4.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 4.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 1.0 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 3.3 GO:0015871 choline transport(GO:0015871)
0.2 3.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 4.7 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 2.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 1.2 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.2 2.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 2.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 5.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 4.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.2 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 10.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 1.9 GO:0015820 leucine transport(GO:0015820)
0.2 1.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.2 0.2 GO:0046108 uridine metabolic process(GO:0046108)
0.2 0.8 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 4.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 3.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 3.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 2.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.4 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.2 1.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 12.1 GO:0050909 sensory perception of taste(GO:0050909)
0.2 1.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 0.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 4.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.2 1.1 GO:0030047 actin modification(GO:0030047)
0.2 0.4 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.2 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.2 3.5 GO:0031034 myosin filament assembly(GO:0031034)
0.2 0.2 GO:0033082 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826) regulation of extrathymic T cell differentiation(GO:0033082)
0.2 1.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 4.7 GO:0033622 integrin activation(GO:0033622)
0.2 3.3 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.2 1.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 1.5 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.2 2.1 GO:0034214 protein hexamerization(GO:0034214)
0.2 2.3 GO:0051665 membrane raft localization(GO:0051665)
0.2 1.4 GO:0003383 apical constriction(GO:0003383)
0.2 0.3 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.2 0.9 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.2 1.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 2.6 GO:0046834 lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854)
0.2 1.1 GO:0031648 protein destabilization(GO:0031648)
0.1 2.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 4.4 GO:0016180 snRNA processing(GO:0016180)
0.1 2.0 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.7 GO:0048749 compound eye development(GO:0048749)
0.1 1.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 5.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 0.4 GO:2000981 auditory receptor cell fate determination(GO:0042668) negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.4 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 1.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 1.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) maintenance of DNA repeat elements(GO:0043570) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.5 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 1.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.8 GO:1901906 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.1 1.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 3.9 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.1 1.6 GO:0061458 reproductive system development(GO:0061458)
0.1 0.9 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 1.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.4 GO:1901656 glycoside transport(GO:1901656)
0.1 1.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.9 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 2.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.8 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 2.5 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 1.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 5.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 11.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 2.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.6 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.7 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 1.0 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 1.2 GO:0014010 Schwann cell proliferation(GO:0014010)
0.1 2.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 4.5 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.1 1.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 4.4 GO:0060074 synapse maturation(GO:0060074)
0.1 0.5 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993)
0.1 3.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 2.0 GO:0036065 fucosylation(GO:0036065)
0.1 0.4 GO:0009447 putrescine catabolic process(GO:0009447)
0.1 0.7 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.6 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 3.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.6 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.4 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 2.7 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 1.7 GO:0007172 signal complex assembly(GO:0007172)
0.1 3.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.4 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.3 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 10.3 GO:0007032 endosome organization(GO:0007032)
0.1 0.6 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.1 1.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 1.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.4 GO:0003335 corneocyte development(GO:0003335)
0.1 0.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.1 2.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 0.9 GO:0070459 prolactin secretion(GO:0070459)
0.1 2.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 5.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 2.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 6.0 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.8 GO:0070779 sulfur amino acid transport(GO:0000101) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.5 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.7 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.4 GO:0019388 galactose catabolic process(GO:0019388)
0.1 2.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.2 GO:0061056 sclerotome development(GO:0061056)
0.1 1.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 5.8 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.6 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:0006477 protein sulfation(GO:0006477)
0.1 3.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 8.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 3.8 GO:1901998 toxin transport(GO:1901998)
0.1 1.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 1.5 GO:0045116 protein neddylation(GO:0045116)
0.1 0.4 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 13.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.9 GO:0031334 positive regulation of protein complex assembly(GO:0031334)
0.1 1.7 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 1.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.8 GO:0021854 hypothalamus development(GO:0021854)
0.1 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.1 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.3 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 1.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.4 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 2.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 2.9 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.6 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.7 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 5.8 GO:0070268 cornification(GO:0070268)
0.0 0.5 GO:0070828 heterochromatin organization(GO:0070828)
0.0 3.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 3.9 GO:0032392 DNA geometric change(GO:0032392)
0.0 2.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0006404 RNA import into nucleus(GO:0006404) snRNA transport(GO:0051030) snRNA import into nucleus(GO:0061015)
0.0 0.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 1.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.5 GO:0031214 biomineral tissue development(GO:0031214)
0.0 0.4 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.8 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 4.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 2.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 1.8 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 0.8 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 1.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:1904353 regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.4 GO:0048511 rhythmic process(GO:0048511)
0.0 0.6 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 1.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 2.8 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:1903280 regulation of amino acid import(GO:0010958) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 1.3 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.3 GO:0045453 bone resorption(GO:0045453)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.4 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 1.0 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 1.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 1.3 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 1.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 3.0 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.9 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 1.6 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.0 GO:0002545 microglial cell activation involved in immune response(GO:0002282) chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.8 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.1 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) succinyl-CoA pathway(GO:0006781) uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.4 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.5 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0015732 prostaglandin transport(GO:0015732)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 16.5 GO:0097209 epidermal lamellar body(GO:0097209)
2.2 17.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.5 15.4 GO:0005955 calcineurin complex(GO:0005955)
1.5 18.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.1 19.5 GO:0031089 platelet dense granule lumen(GO:0031089)
1.0 5.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.9 3.7 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.9 2.6 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.8 9.3 GO:0005610 laminin-5 complex(GO:0005610)
0.8 5.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.8 5.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.7 3.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.7 8.5 GO:0005593 FACIT collagen trimer(GO:0005593)
0.6 1.9 GO:0036457 keratohyalin granule(GO:0036457)
0.6 1.2 GO:0098590 plasma membrane region(GO:0098590)
0.5 5.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.5 15.2 GO:0034706 sodium channel complex(GO:0034706)
0.4 2.5 GO:0031673 H zone(GO:0031673)
0.4 2.0 GO:0035838 growing cell tip(GO:0035838)
0.4 1.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.4 6.3 GO:0061700 GATOR2 complex(GO:0061700)
0.3 7.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 3.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 2.7 GO:0070695 FHF complex(GO:0070695)
0.3 7.0 GO:0005916 fascia adherens(GO:0005916)
0.3 2.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.3 3.5 GO:0072687 meiotic spindle(GO:0072687)
0.3 1.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.3 4.4 GO:0032039 integrator complex(GO:0032039)
0.3 1.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.3 1.3 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.3 3.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 1.0 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 6.3 GO:0005922 connexon complex(GO:0005922)
0.2 3.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 2.0 GO:0035976 AP1 complex(GO:0035976)
0.2 25.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 5.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 2.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 2.8 GO:0005883 neurofilament(GO:0005883)
0.2 5.2 GO:0000786 nucleosome(GO:0000786)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.2 2.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 1.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.8 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 1.0 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 2.1 GO:0032993 protein-DNA complex(GO:0032993)
0.2 0.5 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.2 2.7 GO:0045179 apical cortex(GO:0045179)
0.2 3.1 GO:0060077 inhibitory synapse(GO:0060077)
0.2 19.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 1.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 2.0 GO:0005642 annulate lamellae(GO:0005642)
0.1 2.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.1 GO:0032437 cuticular plate(GO:0032437)
0.1 1.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 9.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.6 GO:0032449 CBM complex(GO:0032449)
0.1 17.1 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 2.3 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.0 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 2.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.4 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.1 3.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.8 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.1 GO:0097255 R2TP complex(GO:0097255)
0.1 12.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.0 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.3 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.8 GO:0044294 dendritic growth cone(GO:0044294)
0.1 3.1 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.6 GO:0032433 filopodium tip(GO:0032433)
0.1 2.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.4 GO:0070852 cell body fiber(GO:0070852)
0.1 6.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.6 GO:0097440 apical dendrite(GO:0097440)
0.1 2.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 16.7 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.0 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.7 GO:0071437 invadopodium(GO:0071437)
0.1 3.2 GO:0097228 sperm principal piece(GO:0097228)
0.1 3.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 3.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 6.3 GO:0035580 specific granule lumen(GO:0035580)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 4.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 6.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.7 GO:0016592 mediator complex(GO:0016592)
0.1 5.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 28.4 GO:0000790 nuclear chromatin(GO:0000790)
0.1 6.2 GO:0005811 lipid particle(GO:0005811)
0.1 1.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.7 GO:0043034 costamere(GO:0043034)
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.1 2.9 GO:0031430 M band(GO:0031430)
0.1 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.0 8.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 2.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.2 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 2.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 6.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.6 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 4.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 2.3 GO:0030027 lamellipodium(GO:0030027)
0.0 1.4 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 1.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 5.8 GO:0031674 I band(GO:0031674)
0.0 3.7 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 3.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 5.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.7 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 3.7 GO:0055037 recycling endosome(GO:0055037)
0.0 3.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 25.6 GO:0016604 nuclear body(GO:0016604)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.5 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 4.9 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.4 GO:0045202 synapse(GO:0045202)
0.0 0.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.9 GO:0045178 basal part of cell(GO:0045178)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.0 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.6 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.9 14.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
2.4 16.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
2.3 23.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.3 5.2 GO:0070012 oligopeptidase activity(GO:0070012)
1.2 8.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.1 25.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.1 16.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.0 14.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
1.0 3.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.9 4.6 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.9 8.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.9 14.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.8 2.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.8 3.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.7 2.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.7 2.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.7 4.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.7 12.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.7 3.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.7 2.6 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.6 1.9 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.6 4.7 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.6 7.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.6 6.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6 5.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.5 11.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 4.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.5 2.1 GO:0036033 mediator complex binding(GO:0036033)
0.5 8.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.5 2.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 2.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.5 3.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.5 6.7 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.4 1.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 15.3 GO:0004707 MAP kinase activity(GO:0004707)
0.4 1.7 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.4 5.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 8.5 GO:0048018 receptor agonist activity(GO:0048018)
0.4 7.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.4 6.0 GO:0042608 T cell receptor binding(GO:0042608)
0.4 1.1 GO:0019808 polyamine binding(GO:0019808)
0.4 1.4 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 5.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 2.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.3 4.9 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.3 3.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 1.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 9.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 1.3 GO:0035501 MH1 domain binding(GO:0035501)
0.3 2.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.3 7.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 1.0 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.3 1.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.3 1.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.3 4.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 1.6 GO:0035500 MH2 domain binding(GO:0035500)
0.3 3.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 1.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3 2.6 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 15.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.3 1.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.3 1.1 GO:0048030 disaccharide binding(GO:0048030)
0.3 2.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 19.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 2.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.7 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.2 3.1 GO:0031419 cobalamin binding(GO:0031419)
0.2 5.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 1.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 11.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 12.8 GO:0042379 chemokine receptor binding(GO:0042379)
0.2 4.7 GO:0008494 translation activator activity(GO:0008494)
0.2 1.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.2 2.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 1.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 1.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 2.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.4 GO:0043426 MRF binding(GO:0043426)
0.2 1.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.2 GO:0097001 ceramide binding(GO:0097001)
0.2 1.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 2.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 2.6 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.2 2.2 GO:0045159 myosin II binding(GO:0045159)
0.2 2.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.9 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 2.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.2 3.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 2.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 1.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 1.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 5.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.3 GO:0042835 BRE binding(GO:0042835)
0.2 3.3 GO:0051400 BH domain binding(GO:0051400)
0.2 0.5 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 15.5 GO:0002039 p53 binding(GO:0002039)
0.1 1.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 1.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.8 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 2.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.8 GO:0052841 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 1.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 39.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 11.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.1 1.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 1.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 5.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0071253 connexin binding(GO:0071253)
0.1 2.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 3.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 5.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.6 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 4.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.2 GO:0008143 poly(A) binding(GO:0008143)
0.1 5.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.8 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 2.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.6 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 4.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 2.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 2.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 21.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 4.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 4.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.0 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 2.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 3.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.3 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 9.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 8.2 GO:0019003 GDP binding(GO:0019003)
0.1 2.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 4.2 GO:0050699 WW domain binding(GO:0050699)
0.1 2.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.9 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 2.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 4.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.1 1.0 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0003774 motor activity(GO:0003774)
0.1 0.8 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 3.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 1.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.5 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.8 GO:0008483 transaminase activity(GO:0008483)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.8 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 1.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 8.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 4.8 GO:0008134 transcription factor binding(GO:0008134)
0.1 1.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.1 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 3.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.8 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 6.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 1.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 1.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 2.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 1.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 9.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 12.8 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 7.3 GO:0005506 iron ion binding(GO:0005506)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 3.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 6.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 3.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 2.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.3 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 2.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 15.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 16.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.5 12.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 11.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 30.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.3 3.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 16.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 14.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 52.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 6.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 11.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 9.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 3.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 5.6 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 9.3 PID RHOA PATHWAY RhoA signaling pathway
0.1 5.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 9.8 PID SHP2 PATHWAY SHP2 signaling
0.1 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 10.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 6.0 PID AURORA B PATHWAY Aurora B signaling
0.1 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 8.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.6 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 5.2 PID AURORA A PATHWAY Aurora A signaling
0.1 2.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 10.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 4.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 5.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 7.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.4 PID CDC42 PATHWAY CDC42 signaling events
0.1 0.9 PID IL27 PATHWAY IL27-mediated signaling events
0.1 4.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.2 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 8.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 16.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7 15.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.6 31.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 34.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 10.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 2.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 3.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 9.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 12.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.3 6.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 4.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 2.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 4.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 12.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 19.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 4.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 2.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 14.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.2 3.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 2.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 7.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 5.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 3.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 3.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 4.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 6.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 2.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 12.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 5.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 2.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 4.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME OPIOID SIGNALLING Genes involved in Opioid Signalling
0.0 0.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 3.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 3.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 3.0 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 3.7 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME OPSINS Genes involved in Opsins