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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF524

Z-value: 2.21

Motif logo

Transcription factors associated with ZNF524

Gene Symbol Gene ID Gene Info
ENSG00000171443.6 zinc finger protein 524

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF524hg19_v2_chr19_+_56111680_561117350.921.6e-08Click!

Activity profile of ZNF524 motif

Sorted Z-values of ZNF524 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF524

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
1.5 4.4 GO:0043181 vacuolar sequestering(GO:0043181)
1.5 7.3 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
1.0 3.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.9 5.5 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.7 2.0 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.7 2.0 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.6 2.4 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.6 1.7 GO:1905026 regulation of heart looping(GO:1901207) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.5 2.1 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.5 1.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.5 4.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.4 3.1 GO:0060356 leucine import(GO:0060356)
0.4 3.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 1.2 GO:0021546 rhombomere development(GO:0021546)
0.4 5.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.4 1.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.4 3.9 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.4 1.2 GO:0035283 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 1.2 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.4 2.2 GO:0048389 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.4 2.6 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.4 1.9 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.4 1.8 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.4 2.5 GO:0003180 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180) endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) notochord formation(GO:0014028)
0.4 1.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.3 1.0 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.3 1.9 GO:0097327 response to antineoplastic agent(GO:0097327)
0.3 0.9 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.3 2.2 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.3 1.9 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.3 1.1 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.3 2.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3 1.9 GO:1903232 melanosome assembly(GO:1903232)
0.3 1.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 1.6 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.3 0.8 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.3 0.8 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.3 7.2 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.3 2.1 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.3 0.8 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.2 0.7 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.2 1.0 GO:0060535 trachea cartilage morphogenesis(GO:0060535) inner medullary collecting duct development(GO:0072061)
0.2 0.7 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 1.0 GO:1990502 dense core granule maturation(GO:1990502)
0.2 2.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 0.5 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.2 0.7 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 1.8 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.2 2.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.2 0.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 1.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 1.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 2.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 0.7 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 0.6 GO:0042732 D-xylose metabolic process(GO:0042732)
0.2 0.9 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.6 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.2 1.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 2.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2 0.6 GO:0006147 guanine catabolic process(GO:0006147)
0.2 0.6 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 0.6 GO:0018874 benzoate metabolic process(GO:0018874)
0.2 0.6 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 1.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.2 1.5 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.7 GO:0090410 malonate catabolic process(GO:0090410)
0.2 0.2 GO:0006565 L-serine catabolic process(GO:0006565)
0.2 1.1 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 0.5 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.2 0.5 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.2 0.9 GO:0043335 protein unfolding(GO:0043335)
0.2 0.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 1.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 0.3 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.2 1.2 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.2 1.0 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.2 6.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 0.8 GO:0019303 D-ribose catabolic process(GO:0019303)
0.2 0.7 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 0.8 GO:0035106 operant conditioning(GO:0035106)
0.2 0.6 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.2 1.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.2 0.3 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.2 0.9 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 3.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 0.6 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.2 2.9 GO:0071318 cellular response to ATP(GO:0071318)
0.2 0.9 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.2 0.8 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.2 1.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.6 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.7 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 1.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 1.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.7 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 0.6 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.4 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.4 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.1 1.0 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.4 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.4 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.5 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.4 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 2.6 GO:0051601 exocyst localization(GO:0051601)
0.1 0.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.8 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.4 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 1.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 1.7 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.1 0.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 2.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.4 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 1.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.6 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.1 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 2.8 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.1 2.0 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.9 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.5 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.1 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.1 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.7 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 0.8 GO:0051715 cytolysis in other organism(GO:0051715)
0.1 2.4 GO:0031167 rRNA methylation(GO:0031167)
0.1 2.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.0 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.1 0.8 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 1.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 7.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.7 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 2.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.8 GO:0042262 DNA protection(GO:0042262)
0.1 0.6 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.1 0.3 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 2.1 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:0003068 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.7 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 1.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.9 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.4 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.7 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.4 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 1.4 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 1.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.8 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 3.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.1 GO:0044351 macropinocytosis(GO:0044351)
0.1 1.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 2.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.4 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.4 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 1.0 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.4 GO:2000035 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.4 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.4 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 2.1 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1 1.6 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0051384 response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 1.7 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 3.5 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.1 0.6 GO:0044804 nucleophagy(GO:0044804)
0.1 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.2 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.3 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.7 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 1.9 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 0.3 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.7 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.5 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.2 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.1 0.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 0.6 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.5 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.8 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.1 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.6 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 6.4 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.9 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 0.4 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 1.0 GO:0033198 response to ATP(GO:0033198)
0.1 1.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.6 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 0.5 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 1.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 1.0 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.1 0.4 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.5 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 0.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.4 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 1.0 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.3 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 1.6 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 1.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.8 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.5 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.0 1.0 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 2.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.5 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 2.0 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.4 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.3 GO:0044650 adhesion of symbiont to host cell(GO:0044650)
0.0 0.3 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.6 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 4.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.5 GO:0009650 UV protection(GO:0009650)
0.0 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.7 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.6 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:0060374 mast cell differentiation(GO:0060374) mast cell proliferation(GO:0070662)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.5 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:1901858 regulation of mitochondrial DNA metabolic process(GO:1901858)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 2.0 GO:0048536 spleen development(GO:0048536)
0.0 0.5 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 1.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.4 GO:0042940 D-amino acid transport(GO:0042940)
0.0 3.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 1.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.9 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 2.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.8 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 3.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.3 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.4 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 1.7 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 1.4 GO:0009268 response to pH(GO:0009268)
0.0 0.6 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 1.1 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0061441 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0051971 negative regulation of transmission of nerve impulse(GO:0051970) positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.7 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.7 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.9 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.5 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0032506 cytokinetic process(GO:0032506)
0.0 2.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.3 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.0 0.4 GO:0046697 decidualization(GO:0046697)
0.0 0.3 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0001510 RNA methylation(GO:0001510)
0.0 0.4 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.2 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.9 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.1 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.1 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.7 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.5 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.1 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0005927 muscle tendon junction(GO:0005927)
0.5 2.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.4 3.1 GO:0031262 Ndc80 complex(GO:0031262)
0.4 3.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 3.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.0 GO:0035101 FACT complex(GO:0035101)
0.3 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.3 1.2 GO:0044753 amphisome(GO:0044753)
0.3 2.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 1.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 1.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 3.9 GO:0031931 TORC1 complex(GO:0031931)
0.2 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.2 1.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 0.9 GO:1990423 RZZ complex(GO:1990423)
0.2 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 2.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 2.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.2 1.7 GO:0035976 AP1 complex(GO:0035976)
0.2 1.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.2 2.6 GO:0070652 HAUS complex(GO:0070652)
0.2 0.7 GO:0031251 PAN complex(GO:0031251)
0.2 1.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 0.9 GO:0043260 laminin-11 complex(GO:0043260)
0.2 2.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 3.9 GO:0005861 troponin complex(GO:0005861)
0.2 2.9 GO:0071438 invadopodium membrane(GO:0071438)
0.2 0.6 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 2.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.0 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 2.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.7 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.7 GO:0005687 U4 snRNP(GO:0005687)
0.1 1.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.7 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.8 GO:0001652 granular component(GO:0001652)
0.1 0.9 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.1 6.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.5 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.9 GO:0005827 polar microtubule(GO:0005827)
0.1 1.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.9 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 2.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 2.0 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.9 GO:0032009 early phagosome(GO:0032009)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.6 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 2.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 2.6 GO:0000145 exocyst(GO:0000145)
0.1 0.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 1.5 GO:0005915 zonula adherens(GO:0005915)
0.1 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.5 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 0.2 GO:0036457 keratohyalin granule(GO:0036457)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 1.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:0030914 STAGA complex(GO:0030914)
0.0 0.8 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 7.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 3.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0042827 platelet dense granule membrane(GO:0031088) platelet dense granule(GO:0042827)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 3.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 12.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 2.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.3 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 8.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.8 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 11.0 GO:0019770 IgG receptor activity(GO:0019770)
1.5 4.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
1.4 5.5 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.9 1.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.8 2.4 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.7 2.0 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.6 1.9 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.5 1.5 GO:0031177 phosphopantetheine binding(GO:0031177)
0.5 6.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.5 1.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 1.8 GO:0047708 biotinidase activity(GO:0047708)
0.5 2.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.4 2.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.4 1.8 GO:0004967 glucagon receptor activity(GO:0004967)
0.4 2.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.4 1.2 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.4 2.9 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.4 1.6 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.4 2.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.4 2.8 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.4 1.2 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.4 2.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 4.6 GO:0031014 troponin T binding(GO:0031014)
0.3 3.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 1.6 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.3 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 0.9 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.3 0.9 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 4.5 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.3 1.9 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 1.0 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 1.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 0.7 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.2 0.7 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.2 0.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.7 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.2 2.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 1.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 0.7 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.2 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 1.4 GO:0030291 cAMP-dependent protein kinase inhibitor activity(GO:0004862) protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 0.7 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 0.9 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.2 0.7 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2 0.6 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 1.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 1.5 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 2.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 2.5 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.6 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 1.0 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 1.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 4.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 0.8 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.7 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.2 2.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 1.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2 3.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 1.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.8 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 2.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.5 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.2 1.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.5 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 1.1 GO:0070513 death domain binding(GO:0070513)
0.2 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.6 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.7 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.6 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.4 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 1.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.5 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 2.4 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.5 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 1.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.5 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.1 1.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.5 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 3.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.9 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 0.3 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 2.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 6.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.6 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.6 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.5 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.3 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.1 0.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.4 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 1.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 2.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 2.0 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.6 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.7 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.6 GO:0070404 NADH binding(GO:0070404)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 1.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.6 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 1.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.9 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.2 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.1 1.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 1.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.8 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.6 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.2 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.8 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 1.2 GO:0008494 translation activator activity(GO:0008494)
0.1 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.3 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 1.4 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 2.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.6 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.4 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 2.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0016594 glycine binding(GO:0016594)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 7.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0019239 deaminase activity(GO:0019239)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 2.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 2.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 1.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.4 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.9 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 10.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 1.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.6 PID IFNG PATHWAY IFN-gamma pathway
0.1 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 5.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 4.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 5.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 5.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.9 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 2.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 3.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.3 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 7.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 4.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 5.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 4.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 1.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 0.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.2 3.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 7.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 2.0 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 3.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 8.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 3.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 7.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 6.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 0.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 1.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 2.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 2.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 4.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.0 REACTOME G1 S TRANSITION Genes involved in G1/S Transition
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 4.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism