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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for ZNF740_ZNF219
Z-value: 2.28
Motif logo
Transcription factors associated with ZNF740_ZNF219
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ZNF740
|
ENSG00000139651.9 | zinc finger protein 740 |
|
ZNF219
|
ENSG00000165804.11 | zinc finger protein 219 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF219 | hg19_v2_chr14_-_21566731_21566836 | -0.87 | 6.1e-07 | Click! |
| ZNF740 | hg19_v2_chr12_+_53574464_53574539 | 0.24 | 3.0e-01 | Click! |
Activity profile of ZNF740_ZNF219 motif
Sorted Z-values of ZNF740_ZNF219 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF740_ZNF219
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 9.4 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 1.9 | 9.7 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 1.3 | 3.8 | GO:1904328 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 1.0 | 15.3 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.8 | 7.5 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.8 | 7.4 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.8 | 2.4 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
| 0.8 | 4.7 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.8 | 7.7 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.8 | 2.3 | GO:0002605 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 0.7 | 2.2 | GO:0001172 | transcription, RNA-templated(GO:0001172) |
| 0.7 | 2.0 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.6 | 3.2 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 0.6 | 4.5 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.6 | 2.3 | GO:0032771 | regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910) |
| 0.6 | 1.7 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.5 | 1.6 | GO:0003169 | coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.5 | 2.0 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.5 | 0.5 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 0.5 | 6.5 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.5 | 4.1 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.5 | 4.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.4 | 1.3 | GO:0061010 | external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010) |
| 0.4 | 1.7 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 0.4 | 1.6 | GO:0031455 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.4 | 2.4 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.4 | 3.9 | GO:1904379 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.4 | 1.8 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.4 | 1.8 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.3 | 1.7 | GO:1902534 | single-organism membrane invagination(GO:1902534) |
| 0.3 | 2.3 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.3 | 1.3 | GO:0007403 | glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) |
| 0.3 | 0.3 | GO:0042474 | middle ear morphogenesis(GO:0042474) |
| 0.3 | 1.8 | GO:0097676 | histone H3-K36 dimethylation(GO:0097676) |
| 0.3 | 1.5 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
| 0.3 | 1.2 | GO:1901994 | negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 0.3 | 3.9 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.3 | 0.9 | GO:0072361 | regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) |
| 0.3 | 0.6 | GO:0060214 | endocardium formation(GO:0060214) |
| 0.3 | 2.9 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.3 | 3.1 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.3 | 0.8 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.3 | 0.8 | GO:0060738 | epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) |
| 0.3 | 3.2 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.3 | 3.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.3 | 3.1 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.3 | 11.1 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.3 | 1.0 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 0.2 | 1.7 | GO:0003408 | optic cup formation involved in camera-type eye development(GO:0003408) |
| 0.2 | 1.0 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 0.2 | 3.4 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.2 | 1.2 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.2 | 1.6 | GO:1902162 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.2 | 1.1 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.2 | 2.8 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.2 | 0.6 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 0.2 | 0.2 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.2 | 2.0 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.2 | 0.6 | GO:0098972 | dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972) |
| 0.2 | 1.5 | GO:0032485 | Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485) |
| 0.2 | 0.6 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
| 0.2 | 1.1 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.2 | 2.8 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.2 | 1.7 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 0.2 | 0.7 | GO:1990927 | vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927) |
| 0.2 | 2.2 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.2 | 6.7 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.2 | 0.7 | GO:1900241 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.2 | 1.0 | GO:0071422 | succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) |
| 0.2 | 5.0 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.2 | 4.7 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.2 | 0.7 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.2 | 1.0 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 0.2 | 0.9 | GO:0072752 | cellular response to rapamycin(GO:0072752) |
| 0.2 | 1.1 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.2 | 3.0 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.1 | 0.6 | GO:0044334 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.1 | 0.3 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.1 | 0.6 | GO:0051413 | response to cortisone(GO:0051413) |
| 0.1 | 2.4 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.1 | 1.0 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 1.4 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 0.1 | 0.7 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.1 | 0.6 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.1 | 0.4 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
| 0.1 | 0.5 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
| 0.1 | 1.9 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.1 | 12.9 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.1 | 1.2 | GO:0019856 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
| 0.1 | 1.5 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.1 | 0.4 | GO:1990654 | sebum secreting cell proliferation(GO:1990654) |
| 0.1 | 0.7 | GO:1902617 | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) response to fluoride(GO:1902617) |
| 0.1 | 1.5 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.1 | 22.6 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.1 | 2.8 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 0.7 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.1 | 0.9 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.1 | 0.9 | GO:2000490 | negative regulation of hepatic stellate cell activation(GO:2000490) |
| 0.1 | 2.3 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.1 | 2.3 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 0.6 | GO:1902904 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.1 | 1.7 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.1 | 2.7 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 0.1 | 1.2 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375) |
| 0.1 | 1.3 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
| 0.1 | 0.3 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.1 | 0.8 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.1 | 1.6 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.1 | 0.8 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.1 | 0.9 | GO:0070885 | positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
| 0.1 | 3.1 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.1 | 0.3 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.1 | 0.8 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.1 | 3.0 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 0.5 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.1 | 0.9 | GO:0043697 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 0.1 | 0.9 | GO:2000491 | regulation of hepatic stellate cell activation(GO:2000489) positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.1 | 1.9 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 1.3 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.1 | 0.3 | GO:0021766 | hippocampus development(GO:0021766) |
| 0.1 | 0.8 | GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949) |
| 0.1 | 1.8 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.1 | 0.5 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.1 | 0.3 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.1 | 0.3 | GO:0051125 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) regulation of actin nucleation(GO:0051125) |
| 0.1 | 1.4 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 0.4 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.1 | 1.7 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 0.3 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.1 | 0.7 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.1 | 1.5 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.1 | 0.7 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 0.5 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.1 | 2.9 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.1 | 0.7 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.1 | 1.5 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.1 | 1.8 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.1 | 1.8 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
| 0.1 | 1.0 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.1 | 0.4 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.1 | 1.3 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.1 | 0.2 | GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619) |
| 0.1 | 0.4 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 0.1 | 1.0 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.3 | GO:0017055 | plasmacytoid dendritic cell activation(GO:0002270) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) regulation of restriction endodeoxyribonuclease activity(GO:0032072) |
| 0.1 | 1.9 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 0.9 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 4.2 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 1.9 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.1 | 0.2 | GO:1904562 | phosphatidylinositol 5-phosphate metabolic process(GO:1904562) |
| 0.1 | 0.7 | GO:2000664 | positive regulation of interleukin-5 secretion(GO:2000664) |
| 0.1 | 0.3 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 0.1 | 1.7 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.1 | 0.6 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.1 | 0.8 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.1 | 1.0 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 1.5 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.1 | 0.3 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.1 | 1.9 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.6 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 0.1 | 0.2 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 0.1 | 3.8 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.1 | 5.0 | GO:0001885 | endothelial cell development(GO:0001885) |
| 0.1 | 1.3 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.1 | 0.1 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
| 0.1 | 0.3 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.1 | 0.4 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.1 | 1.4 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 0.6 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 1.6 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 1.1 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
| 0.1 | 0.3 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.0 | 1.2 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.0 | 0.3 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.0 | 0.6 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 1.3 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.0 | 0.3 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.0 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.0 | 0.3 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 0.0 | 0.2 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.0 | 0.5 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.0 | 0.6 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.6 | GO:0030282 | bone mineralization(GO:0030282) |
| 0.0 | 1.0 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
| 0.0 | 0.6 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.0 | 2.7 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.0 | 0.1 | GO:0072579 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
| 0.0 | 0.1 | GO:0006424 | glutamyl-tRNA aminoacylation(GO:0006424) |
| 0.0 | 0.3 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.0 | 0.9 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 1.5 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.0 | 7.4 | GO:0006333 | chromatin assembly or disassembly(GO:0006333) |
| 0.0 | 1.4 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.0 | 0.2 | GO:2000814 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.0 | 0.7 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 2.5 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.8 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.0 | 1.8 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 0.6 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.0 | 0.5 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.0 | 0.1 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.0 | 0.3 | GO:0006983 | ER overload response(GO:0006983) |
| 0.0 | 0.8 | GO:0007614 | short-term memory(GO:0007614) |
| 0.0 | 0.5 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.0 | 0.6 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.0 | 0.2 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.0 | 0.3 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.0 | 0.4 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.0 | 0.5 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
| 0.0 | 0.0 | GO:0072367 | regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) |
| 0.0 | 0.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.0 | 2.7 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.4 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.0 | 0.1 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 0.0 | 2.4 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.3 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.0 | 0.4 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.0 | 0.2 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.0 | 0.8 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.1 | GO:0035822 | meiotic gene conversion(GO:0006311) gene conversion(GO:0035822) |
| 0.0 | 4.0 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 0.7 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.0 | 0.4 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.0 | 0.5 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.4 | GO:0045814 | negative regulation of gene expression, epigenetic(GO:0045814) |
| 0.0 | 0.1 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.0 | 0.2 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.0 | 0.0 | GO:0030908 | intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) |
| 0.0 | 0.2 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.0 | 0.3 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 0.3 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.0 | 1.1 | GO:1990090 | cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.0 | 0.2 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 0.6 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 0.0 | GO:2000669 | negative regulation of dendritic cell apoptotic process(GO:2000669) |
| 0.0 | 0.1 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.0 | 0.1 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.0 | 0.2 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.0 | 0.5 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.0 | 0.1 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.0 | 0.4 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.0 | 1.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 0.0 | GO:0051586 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
| 0.0 | 0.3 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.1 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.0 | 0.9 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 0.9 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 0.9 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.6 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 2.7 | GO:0071427 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.3 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.0 | 0.4 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.0 | 0.4 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 0.2 | GO:0050680 | negative regulation of epithelial cell proliferation(GO:0050680) |
| 0.0 | 0.1 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.0 | 0.2 | GO:0039702 | viral budding via host ESCRT complex(GO:0039702) |
| 0.0 | 1.0 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.1 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.0 | 0.2 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.8 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 0.6 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 5.1 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 0.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.1 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
| 0.0 | 0.4 | GO:1902186 | regulation of viral release from host cell(GO:1902186) |
| 0.0 | 0.2 | GO:0051292 | nuclear pore organization(GO:0006999) nuclear pore complex assembly(GO:0051292) endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.0 | 0.0 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 0.0 | 0.2 | GO:0071880 | adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880) |
| 0.0 | 0.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.3 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.1 | GO:0007512 | adult heart development(GO:0007512) |
| 0.0 | 0.4 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.3 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.3 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.0 | 0.1 | GO:0003170 | heart valve development(GO:0003170) coronary vasculature development(GO:0060976) |
| 0.0 | 0.1 | GO:0060283 | negative regulation of oocyte development(GO:0060283) regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 4.6 | GO:0031213 | RSF complex(GO:0031213) |
| 0.7 | 4.5 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.7 | 19.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.6 | 0.6 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.6 | 1.7 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
| 0.5 | 2.4 | GO:0035838 | growing cell tip(GO:0035838) |
| 0.4 | 5.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.3 | 3.9 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.3 | 5.0 | GO:0032039 | integrator complex(GO:0032039) |
| 0.3 | 11.3 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.3 | 3.8 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 1.9 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.2 | 3.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.2 | 5.7 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 1.6 | GO:0016589 | NURF complex(GO:0016589) |
| 0.2 | 4.7 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.2 | 0.8 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.2 | 0.9 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
| 0.2 | 0.6 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.2 | 0.9 | GO:0071942 | XPC complex(GO:0071942) |
| 0.2 | 1.7 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 4.8 | GO:0010369 | chromocenter(GO:0010369) |
| 0.2 | 2.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 2.0 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.1 | 1.6 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.1 | 0.7 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 0.1 | 3.6 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.5 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.1 | 1.6 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 2.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.0 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 2.5 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 1.0 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 2.8 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.1 | 1.6 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 0.3 | GO:0075341 | host cell PML body(GO:0075341) |
| 0.1 | 1.8 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 3.4 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 5.0 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 1.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 4.1 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 1.3 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 13.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 0.3 | GO:0031379 | RNA-directed RNA polymerase complex(GO:0031379) |
| 0.1 | 0.4 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.1 | 2.6 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.1 | 1.8 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 2.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 0.2 | GO:0032173 | septin ring(GO:0005940) septin collar(GO:0032173) |
| 0.1 | 1.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 1.0 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 0.3 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 2.2 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 0.5 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 0.9 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 0.6 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.1 | 3.0 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 7.4 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 0.7 | GO:0032009 | early phagosome(GO:0032009) |
| 0.1 | 0.2 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.1 | 0.9 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.1 | 1.0 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.1 | 1.9 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 0.5 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.1 | 9.1 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 0.5 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 3.2 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 1.3 | GO:0044309 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
| 0.0 | 2.2 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.0 | 0.6 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.1 | GO:0005818 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.0 | 1.4 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 1.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 1.7 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 5.1 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.7 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.1 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.7 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 1.7 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.7 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 1.1 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.8 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 1.0 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 0.4 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.4 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 1.0 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 1.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 1.7 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 0.2 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.0 | 1.2 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 1.7 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.6 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 0.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 1.5 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 3.2 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 13.6 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 0.3 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 1.4 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.9 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.5 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 2.9 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 1.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 2.0 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 3.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 1.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 1.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 3.5 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.2 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.1 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.0 | 0.1 | GO:0031417 | NatC complex(GO:0031417) |
| 0.0 | 2.7 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.3 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 1.0 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 12.9 | GO:0016604 | nuclear body(GO:0016604) |
| 0.0 | 0.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 2.4 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 1.7 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 7.2 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 0.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 2.7 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 1.1 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.8 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 1.3 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 1.6 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 1.0 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 9.7 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 0.9 | 4.5 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.7 | 2.2 | GO:0003968 | RNA-directed RNA polymerase activity(GO:0003968) |
| 0.7 | 16.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.7 | 6.7 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.6 | 10.2 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.6 | 2.4 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.6 | 2.3 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.6 | 1.7 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.5 | 1.6 | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity(GO:0004676) |
| 0.5 | 3.4 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.4 | 2.6 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.4 | 4.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.4 | 3.2 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.4 | 1.1 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.4 | 1.5 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.3 | 1.3 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.3 | 2.8 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.3 | 1.2 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 0.3 | 1.4 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
| 0.3 | 2.5 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.3 | 1.6 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.3 | 15.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 2.0 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.2 | 1.0 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
| 0.2 | 3.8 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.2 | 0.9 | GO:0047888 | fatty acid peroxidase activity(GO:0047888) |
| 0.2 | 0.7 | GO:0004019 | adenylosuccinate synthase activity(GO:0004019) |
| 0.2 | 0.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 1.7 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.2 | 1.1 | GO:0030345 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.2 | 1.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.2 | 4.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.2 | 2.7 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.2 | 0.6 | GO:1990698 | palmitoleoyltransferase activity(GO:1990698) |
| 0.2 | 0.6 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.2 | 3.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.2 | 7.5 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.2 | 0.5 | GO:0043849 | Ras palmitoyltransferase activity(GO:0043849) |
| 0.2 | 3.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.2 | 2.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.2 | 4.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.2 | 1.0 | GO:0017153 | succinate transmembrane transporter activity(GO:0015141) sodium:dicarboxylate symporter activity(GO:0017153) |
| 0.2 | 4.7 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.2 | 2.3 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.2 | 3.9 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.2 | 7.4 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 3.7 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 1.6 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.1 | 3.1 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.1 | 1.4 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.1 | 1.6 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.1 | 2.5 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.1 | 7.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 9.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 2.8 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 0.7 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 1.7 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 4.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 0.8 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.1 | 1.5 | GO:0046972 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 0.8 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.1 | 1.7 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 1.0 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 0.4 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.1 | 1.5 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 0.8 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.1 | 0.7 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 0.6 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 30.6 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.1 | 4.3 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 2.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 0.6 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 1.8 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.1 | 1.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 1.2 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.1 | 1.6 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 2.2 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 3.0 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.1 | 0.4 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.1 | 0.2 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 0.1 | 0.4 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.1 | 0.6 | GO:0010853 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.1 | 8.7 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 1.0 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 1.1 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 1.7 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 2.9 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.1 | 1.4 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 1.2 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 1.7 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 0.5 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.1 | 0.4 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 1.4 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 0.6 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 0.4 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.1 | 1.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 8.1 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 1.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 0.2 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.1 | 0.4 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 0.5 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 2.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.7 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 1.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.5 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.0 | 1.6 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.0 | 2.7 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.4 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.6 | GO:0046935 | insulin binding(GO:0043559) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.3 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.0 | 0.1 | GO:0061598 | molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
| 0.0 | 0.7 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.1 | GO:0004818 | glutamate-tRNA ligase activity(GO:0004818) |
| 0.0 | 1.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.4 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.0 | 4.6 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.1 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.0 | 0.5 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.1 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 0.0 | 0.6 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 1.0 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.7 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.0 | 0.3 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 1.9 | GO:0061650 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 1.5 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 1.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.3 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.0 | 0.5 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.7 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 2.2 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.7 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.3 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.0 | 0.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.0 | 2.9 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 1.0 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.3 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.0 | 0.6 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.2 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.0 | 0.4 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 0.3 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.0 | 1.3 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.4 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 3.6 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.7 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 1.8 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.0 | 0.2 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.7 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.7 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 2.0 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 2.0 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.4 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 0.5 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 1.2 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.6 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 2.0 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 2.4 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 1.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.2 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 0.1 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.1 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.3 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.1 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.0 | 0.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 13.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 13.0 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 19.0 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 1.8 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.1 | 3.2 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 5.9 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.1 | 2.4 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.1 | 18.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 10.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 6.9 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 5.4 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 5.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 2.3 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 1.8 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 3.8 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 2.9 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.1 | 3.3 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 0.6 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.1 | 2.8 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 0.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 4.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 1.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 2.6 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.5 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.5 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 1.0 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 3.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.6 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 2.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 2.3 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 4.6 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 2.8 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 3.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.7 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 4.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 2.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.4 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.1 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.4 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.7 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 1.6 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.3 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 0.7 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.2 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.8 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 0.5 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 0.2 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.2 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.1 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 16.5 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.5 | 7.5 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.1 | 6.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 3.5 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 4.1 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.1 | 2.1 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.1 | 2.4 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 4.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 3.0 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.1 | 2.9 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 2.0 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.1 | 2.0 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.1 | 1.6 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 1.4 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 2.4 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 2.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 1.4 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 2.7 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 2.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 2.5 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 6.7 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.1 | 3.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.9 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 0.9 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.1 | 1.0 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.1 | 4.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 1.5 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 1.5 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 3.7 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.8 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.0 | 1.0 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 2.4 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 2.4 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 0.6 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.0 | 2.0 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 1.7 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.0 | 0.3 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.0 | 1.0 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.8 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.6 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 5.8 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 2.9 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 4.9 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 3.6 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 2.5 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 1.2 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.0 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.0 | 1.3 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.0 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 7.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 1.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.2 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 0.8 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.8 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.4 | REACTOME RNA POL II PRE TRANSCRIPTION EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.0 | 1.1 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.5 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.1 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 1.2 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.2 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.3 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 1.9 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.3 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.2 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.0 | 0.4 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |