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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for ZNF784
Z-value: 1.77
Motif logo
Transcription factors associated with ZNF784
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ZNF784
|
ENSG00000179922.5 | zinc finger protein 784 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF784 | hg19_v2_chr19_-_56135928_56135967 | -0.81 | 1.6e-05 | Click! |
Activity profile of ZNF784 motif
Sorted Z-values of ZNF784 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF784
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 9.5 | GO:1902173 | negative regulation of keratinocyte apoptotic process(GO:1902173) |
| 2.5 | 12.4 | GO:0051585 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 1.1 | 11.8 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.9 | 2.6 | GO:2000283 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.8 | 0.8 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 0.7 | 6.5 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.6 | 3.2 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.6 | 20.4 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.5 | 2.1 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.4 | 1.7 | GO:0031077 | post-embryonic camera-type eye development(GO:0031077) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.4 | 1.5 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.3 | 2.2 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.3 | 1.6 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.3 | 7.1 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.3 | 1.4 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.3 | 1.4 | GO:0009183 | purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) |
| 0.2 | 2.0 | GO:1902612 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 0.2 | 1.2 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.2 | 0.9 | GO:0002384 | hepatic immune response(GO:0002384) response to prolactin(GO:1990637) |
| 0.2 | 3.6 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.2 | 3.2 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.2 | 1.7 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.2 | 1.2 | GO:0060268 | negative regulation of respiratory burst(GO:0060268) |
| 0.2 | 1.2 | GO:0048817 | negative regulation of hair follicle maturation(GO:0048817) |
| 0.2 | 2.9 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.2 | 0.6 | GO:0071262 | regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264) |
| 0.2 | 1.5 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.2 | 0.7 | GO:1900155 | regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) |
| 0.2 | 2.3 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.2 | 0.8 | GO:1903844 | regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090101) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
| 0.1 | 1.2 | GO:0060125 | negative regulation of growth hormone secretion(GO:0060125) |
| 0.1 | 1.0 | GO:2000819 | regulation of nucleotide-excision repair(GO:2000819) |
| 0.1 | 0.9 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.1 | 1.5 | GO:0032096 | negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099) |
| 0.1 | 1.2 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.1 | 1.0 | GO:0060702 | negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) |
| 0.1 | 0.8 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 1.4 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 0.1 | 1.5 | GO:0021860 | pyramidal neuron development(GO:0021860) |
| 0.1 | 0.3 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
| 0.1 | 8.3 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
| 0.1 | 0.5 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.1 | 0.6 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.1 | 1.3 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 0.5 | GO:0071874 | cellular response to norepinephrine stimulus(GO:0071874) |
| 0.1 | 0.5 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.1 | 1.9 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.1 | 0.7 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 1.9 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.1 | 0.4 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.1 | 1.2 | GO:0061303 | cornea development in camera-type eye(GO:0061303) |
| 0.1 | 0.2 | GO:0046901 | tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901) |
| 0.1 | 1.6 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 0.2 | GO:0030821 | negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122) regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377) |
| 0.1 | 2.4 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 0.3 | GO:0015966 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
| 0.1 | 2.9 | GO:0048012 | hepatocyte growth factor receptor signaling pathway(GO:0048012) |
| 0.1 | 0.5 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.1 | 1.9 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.1 | 0.4 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 0.2 | GO:0000706 | meiotic DNA double-strand break processing(GO:0000706) |
| 0.1 | 0.6 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
| 0.1 | 0.3 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.1 | 0.1 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.1 | 1.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 0.7 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 1.1 | GO:1903204 | negative regulation of oxidative stress-induced neuron death(GO:1903204) |
| 0.0 | 2.0 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.4 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 1.2 | GO:2000059 | negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059) |
| 0.0 | 0.6 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.0 | 1.0 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.0 | 0.2 | GO:0060995 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.0 | 0.2 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.0 | 0.3 | GO:0019438 | aromatic compound biosynthetic process(GO:0019438) |
| 0.0 | 0.6 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 0.0 | 2.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.9 | GO:0032785 | negative regulation of DNA-templated transcription, elongation(GO:0032785) |
| 0.0 | 1.8 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 1.5 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 2.4 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.0 | 0.6 | GO:0042737 | drug catabolic process(GO:0042737) |
| 0.0 | 1.3 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.0 | 0.5 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
| 0.0 | 2.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.2 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.0 | 0.8 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 1.0 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.0 | 1.1 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 1.2 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.0 | 1.3 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 0.1 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
| 0.0 | 1.0 | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.0 | 1.8 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 11.3 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.0 | 1.5 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.4 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.1 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.0 | 0.3 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
| 0.0 | 0.3 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.0 | 0.8 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.0 | 0.4 | GO:0035745 | T-helper 2 cell cytokine production(GO:0035745) |
| 0.0 | 0.4 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.0 | 0.3 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.0 | 0.5 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.5 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 1.0 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.1 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 0.0 | 0.1 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.0 | 0.2 | GO:0003360 | brainstem development(GO:0003360) |
| 0.0 | 5.0 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.0 | 0.3 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.0 | 0.1 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.4 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.2 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.0 | 0.2 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 0.6 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
| 0.0 | 0.2 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.0 | 0.1 | GO:0099525 | presynaptic dense core granule exocytosis(GO:0099525) |
| 0.0 | 0.1 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.0 | 1.1 | GO:0006283 | transcription-coupled nucleotide-excision repair(GO:0006283) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 14.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.3 | 3.8 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.2 | 7.1 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 1.6 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.2 | 0.9 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.2 | 2.4 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.2 | 2.9 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.2 | 0.9 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.2 | 1.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.2 | 0.8 | GO:0031417 | NatC complex(GO:0031417) |
| 0.2 | 1.4 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.2 | 8.8 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 0.9 | GO:0032044 | DSIF complex(GO:0032044) |
| 0.1 | 0.4 | GO:0070877 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
| 0.1 | 1.2 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.1 | 12.6 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 9.4 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 1.5 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 0.9 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.1 | 1.3 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 2.6 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 1.3 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 1.5 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.1 | 2.9 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 1.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 0.2 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
| 0.1 | 0.6 | GO:0030891 | VCB complex(GO:0030891) |
| 0.1 | 2.6 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 1.0 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 1.5 | GO:0043203 | axon hillock(GO:0043203) |
| 0.1 | 1.6 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 1.2 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 0.5 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
| 0.1 | 2.4 | GO:0031105 | septin complex(GO:0031105) |
| 0.1 | 3.2 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 3.3 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 1.5 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.9 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 1.7 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.3 | GO:0098552 | side of membrane(GO:0098552) |
| 0.0 | 1.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.7 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.4 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.5 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.0 | 2.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.2 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.0 | 5.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.4 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 2.0 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.4 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.4 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 1.5 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.9 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.3 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 2.2 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 2.6 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 1.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 12.2 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 0.3 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.6 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 0.6 | GO:0036126 | sperm flagellum(GO:0036126) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 12.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 1.3 | 6.5 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.9 | 2.6 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.5 | 6.7 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.4 | 11.2 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.4 | 2.2 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.2 | 1.9 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.2 | 1.0 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.1 | 1.2 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.1 | 3.0 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 1.0 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 8.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 0.8 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 0.9 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.1 | 0.6 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.1 | 9.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.1 | 0.9 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 1.6 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 0.1 | 1.5 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.1 | 0.4 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.1 | 8.3 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.1 | 0.4 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 1.5 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.1 | 0.2 | GO:0008841 | tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841) |
| 0.1 | 0.4 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 0.4 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.1 | 0.6 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 3.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 1.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 2.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.3 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.1 | 0.3 | GO:0050253 | retinyl-palmitate esterase activity(GO:0050253) |
| 0.1 | 4.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 1.2 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.1 | 0.2 | GO:0048257 | 3'-flap endonuclease activity(GO:0048257) |
| 0.1 | 1.6 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 0.8 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.1 | 0.6 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.1 | 1.0 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 3.2 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 3.2 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 1.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 7.2 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.9 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 2.5 | GO:0001098 | basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099) |
| 0.0 | 4.0 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.1 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.0 | 11.3 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.0 | 2.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.5 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.0 | 0.1 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 0.0 | 0.9 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 1.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 0.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.0 | 2.1 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.2 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.0 | 0.1 | GO:0045309 | phosphotyrosine binding(GO:0001784) protein phosphorylated amino acid binding(GO:0045309) |
| 0.0 | 0.3 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.0 | 2.3 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.0 | 3.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 1.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.4 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 2.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.3 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.0 | 1.1 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.1 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.0 | 0.4 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 2.2 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.3 | GO:0015926 | glucosidase activity(GO:0015926) |
| 0.0 | 0.7 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.1 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.0 | 0.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.1 | GO:0016453 | C-acetyltransferase activity(GO:0016453) |
| 0.0 | 0.5 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.5 | GO:0001968 | fibronectin binding(GO:0001968) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 10.1 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 12.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.2 | 12.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 3.2 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 10.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 2.0 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 3.5 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 0.9 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.0 | 15.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 3.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.2 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 12.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 3.2 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 1.2 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 2.6 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 1.5 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.6 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.2 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 2.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 2.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.6 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.5 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 12.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 12.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 3.8 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 2.6 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 1.7 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 1.4 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 3.2 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 2.5 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 1.5 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 1.5 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.1 | 9.0 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 1.6 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 1.6 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.6 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 2.7 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.9 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.9 | REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
| 0.0 | 1.6 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.6 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.2 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 1.7 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.7 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.3 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.2 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.0 | 1.8 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.4 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |