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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ALX3

Z-value: 1.02

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Transcription factors associated with ALX3

Gene Symbol Gene ID Gene Info
ALX3
ENSG00000156150.9 ALX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX3hg38_v1_chr1_-_110070654_1100706770.743.6e-02Click!

Activity profile of ALX3 motif

Sorted Z-values of ALX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_104085847 2.10 ENST00000648076.2
COL17A1
collagen type XVII alpha 1 chain
chr18_+_31447732 1.69 ENST00000257189.5
DSG3
desmoglein 3
chr7_+_70596078 1.51 ENST00000644506.1
AUTS2
activator of transcription and developmental regulator AUTS2
chr3_-_151316795 1.44 ENST00000260843.5
GPR87
G protein-coupled receptor 87
chr1_+_27934980 1.40 ENST00000373894.8
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr1_+_27935110 1.30 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr17_-_7263959 1.20 ENST00000571932.2
CLDN7
claudin 7
chr1_+_160400543 1.18 ENST00000368061.3
VANGL2
VANGL planar cell polarity protein 2
chr2_+_68734773 1.09 ENST00000409202.8
ARHGAP25
Rho GTPase activating protein 25
chr5_+_67004618 0.90 ENST00000261569.11
ENST00000436277.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr10_+_24466487 0.86 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
KIAA1217
chr9_-_114348966 0.85 ENST00000374079.8
AKNA
AT-hook transcription factor
chr9_-_5304713 0.80 ENST00000381627.4
RLN2
relaxin 2
chr8_-_85341705 0.79 ENST00000517618.5
CA1
carbonic anhydrase 1
chr2_+_68734861 0.76 ENST00000467265.5
ARHGAP25
Rho GTPase activating protein 25
chr3_-_191282383 0.75 ENST00000427544.6
UTS2B
urotensin 2B
chr6_+_130421086 0.72 ENST00000545622.5
TMEM200A
transmembrane protein 200A
chr6_+_132538290 0.71 ENST00000434551.2
TAAR9
trace amine associated receptor 9
chr13_-_85799400 0.69 ENST00000647374.2
SLITRK6
SLIT and NTRK like family member 6
chr16_-_28623560 0.67 ENST00000350842.8
SULT1A1
sulfotransferase family 1A member 1
chr1_+_27935022 0.66 ENST00000411604.5
ENST00000373888.8
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr7_-_111392915 0.65 ENST00000450877.5
IMMP2L
inner mitochondrial membrane peptidase subunit 2
chrX_+_136536099 0.63 ENST00000440515.5
ENST00000456412.1
VGLL1
vestigial like family member 1
chr4_-_73620391 0.63 ENST00000395777.6
ENST00000307439.10
RASSF6
Ras association domain family member 6
chr1_+_81306096 0.58 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
ADGRL2
adhesion G protein-coupled receptor L2
chr14_-_67412112 0.57 ENST00000216446.9
PLEK2
pleckstrin 2
chr4_-_25863537 0.56 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L3
SEL1L family member 3
chr3_-_112829367 0.56 ENST00000448932.4
ENST00000617549.3
CD200R1L
CD200 receptor 1 like
chr8_+_106726115 0.52 ENST00000521592.5
OXR1
oxidation resistance 1
chr8_+_104223320 0.52 ENST00000339750.3
RIMS2
regulating synaptic membrane exocytosis 2
chr6_+_130018565 0.51 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr3_-_142029108 0.51 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr1_-_99766620 0.50 ENST00000646001.2
FRRS1
ferric chelate reductase 1
chr9_-_5339874 0.48 ENST00000223862.2
RLN1
relaxin 1
chr20_-_52105644 0.47 ENST00000371523.8
ZFP64
ZFP64 zinc finger protein
chr16_+_11965193 0.46 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr11_-_5301946 0.44 ENST00000380224.2
OR51B4
olfactory receptor family 51 subfamily B member 4
chr1_-_247760556 0.43 ENST00000641256.1
OR1C1
olfactory receptor family 1 subfamily C member 1
chr8_+_104223344 0.42 ENST00000523362.5
RIMS2
regulating synaptic membrane exocytosis 2
chrX_+_108045050 0.41 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr11_+_6876625 0.41 ENST00000379829.2
OR10A4
olfactory receptor family 10 subfamily A member 4
chr5_+_140806929 0.40 ENST00000378125.4
ENST00000618834.1
ENST00000530339.2
ENST00000512229.6
ENST00000672575.1
PCDHA4
protocadherin alpha 4
chr4_-_73620629 0.40 ENST00000342081.7
RASSF6
Ras association domain family member 6
chr8_-_85341659 0.40 ENST00000522389.5
CA1
carbonic anhydrase 1
chr8_+_49911801 0.40 ENST00000643809.1
SNTG1
syntrophin gamma 1
chr5_-_140346596 0.40 ENST00000230990.7
HBEGF
heparin binding EGF like growth factor
chr3_-_161105399 0.39 ENST00000652593.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr6_-_53510445 0.37 ENST00000509541.5
GCLC
glutamate-cysteine ligase catalytic subunit
chr3_-_161105224 0.37 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr8_-_90082871 0.36 ENST00000265431.7
CALB1
calbindin 1
chr20_+_33217325 0.36 ENST00000375452.3
ENST00000375454.8
BPIFA3
BPI fold containing family A member 3
chrX_+_108044967 0.36 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr9_+_470291 0.35 ENST00000382303.5
KANK1
KN motif and ankyrin repeat domains 1
chr17_+_37491464 0.35 ENST00000613659.1
DUSP14
dual specificity phosphatase 14
chr3_-_161105070 0.34 ENST00000651430.1
ENST00000650695.1
ENST00000651689.1
ENST00000651916.1
ENST00000488170.5
ENST00000652377.1
ENST00000652669.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr8_+_106726012 0.34 ENST00000449762.6
ENST00000297447.10
OXR1
oxidation resistance 1
chr18_-_55423757 0.34 ENST00000675707.1
TCF4
transcription factor 4
chr2_-_101308681 0.34 ENST00000295317.4
RNF149
ring finger protein 149
chr9_+_121567057 0.33 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr4_+_94974984 0.32 ENST00000672698.1
BMPR1B
bone morphogenetic protein receptor type 1B
chr18_-_55635948 0.31 ENST00000565124.4
ENST00000398339.5
TCF4
transcription factor 4
chr5_+_140821598 0.30 ENST00000614258.1
ENST00000529859.2
ENST00000529619.5
PCDHA5
protocadherin alpha 5
chr1_+_207053229 0.30 ENST00000367080.8
ENST00000367079.3
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr6_+_121437378 0.30 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr2_+_90038848 0.30 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr20_-_31390580 0.29 ENST00000339144.3
ENST00000376321.4
DEFB119
defensin beta 119
chr12_-_86256267 0.29 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr11_+_55827219 0.29 ENST00000378397.1
OR5L2
olfactory receptor family 5 subfamily L member 2
chr1_+_152811971 0.29 ENST00000360090.4
LCE1B
late cornified envelope 1B
chr12_+_26195313 0.28 ENST00000422622.3
SSPN
sarcospan
chr5_-_35938572 0.27 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
CAPSL
calcyphosine like
chr11_+_55811367 0.27 ENST00000625203.2
OR5L1
olfactory receptor family 5 subfamily L member 1
chr4_-_159035226 0.27 ENST00000434826.3
C4orf45
chromosome 4 open reading frame 45
chr14_+_22202561 0.27 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr17_+_39628496 0.27 ENST00000394265.5
ENST00000394267.2
PPP1R1B
protein phosphatase 1 regulatory inhibitor subunit 1B
chr3_+_42979281 0.27 ENST00000488863.5
ENST00000430121.3
GASK1A
golgi associated kinase 1A
chr14_+_22508602 0.27 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr11_-_129024157 0.26 ENST00000392657.7
ARHGAP32
Rho GTPase activating protein 32
chr2_+_90172802 0.26 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr5_+_151259793 0.26 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr20_-_51802433 0.25 ENST00000395997.3
SALL4
spalt like transcription factor 4
chr5_+_55853314 0.25 ENST00000354961.8
ENST00000297015.7
IL31RA
interleukin 31 receptor A
chr6_+_26402237 0.24 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
BTN3A1
butyrophilin subfamily 3 member A1
chr12_+_6904962 0.24 ENST00000415834.5
ENST00000436789.5
LRRC23
leucine rich repeat containing 23
chr20_-_51802509 0.24 ENST00000371539.7
ENST00000217086.9
SALL4
spalt like transcription factor 4
chrX_+_115593570 0.23 ENST00000539310.5
PLS3
plastin 3
chr2_+_90234809 0.23 ENST00000443397.5
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr19_-_35812838 0.23 ENST00000653904.2
PRODH2
proline dehydrogenase 2
chr8_-_7430348 0.22 ENST00000318124.3
DEFB103B
defensin beta 103B
chr13_+_48037692 0.21 ENST00000258662.3
NUDT15
nudix hydrolase 15
chr12_-_21910853 0.21 ENST00000544039.5
ABCC9
ATP binding cassette subfamily C member 9
chr3_+_119579676 0.21 ENST00000357003.7
ADPRH
ADP-ribosylarginine hydrolase
chr11_-_16356538 0.20 ENST00000683767.1
SOX6
SRY-box transcription factor 6
chr2_+_102418642 0.20 ENST00000264260.6
IL18RAP
interleukin 18 receptor accessory protein
chr2_+_102337148 0.19 ENST00000311734.6
ENST00000409584.5
IL1RL1
interleukin 1 receptor like 1
chr16_-_28597042 0.19 ENST00000533150.5
ENST00000335715.9
SULT1A2
sulfotransferase family 1A member 2
chr3_+_122055355 0.19 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chr10_+_125896549 0.18 ENST00000368693.6
FANK1
fibronectin type III and ankyrin repeat domains 1
chr9_+_72577939 0.18 ENST00000645773.1
TMC1
transmembrane channel like 1
chr18_+_58341038 0.18 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr15_+_22015233 0.18 ENST00000639059.1
ENST00000640156.1
ENSG00000285472.1
ENSG00000284500.3
novel protein
novel transcript
chr17_-_66229380 0.18 ENST00000205948.11
APOH
apolipoprotein H
chr17_+_18183803 0.17 ENST00000399138.5
ALKBH5
alkB homolog 5, RNA demethylase
chr6_+_26183750 0.17 ENST00000614097.3
H2BC6
H2B clustered histone 6
chr12_+_26195543 0.17 ENST00000242729.7
SSPN
sarcospan
chr17_-_5035418 0.16 ENST00000254853.10
ENST00000424747.1
SLC52A1
solute carrier family 52 member 1
chr7_-_88226965 0.16 ENST00000490437.5
ENST00000431660.5
SRI
sorcin
chr5_+_141177790 0.16 ENST00000239444.4
ENST00000623995.1
PCDHB8
ENSG00000279472.1
protocadherin beta 8
novel transcript
chr6_+_127577168 0.16 ENST00000329722.8
C6orf58
chromosome 6 open reading frame 58
chr7_-_87713287 0.15 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ABCB1
ATP binding cassette subfamily B member 1
chr7_-_88226987 0.15 ENST00000394641.7
SRI
sorcin
chr12_+_12357418 0.15 ENST00000298571.6
BORCS5
BLOC-1 related complex subunit 5
chr1_-_92486916 0.14 ENST00000294702.6
GFI1
growth factor independent 1 transcriptional repressor
chr7_-_44541262 0.14 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr6_+_26402289 0.14 ENST00000414912.2
BTN3A1
butyrophilin subfamily 3 member A1
chr9_-_112332962 0.14 ENST00000458258.5
ENST00000210227.4
PTBP3
polypyrimidine tract binding protein 3
chr19_-_3557563 0.14 ENST00000389395.7
ENST00000355415.7
MFSD12
major facilitator superfamily domain containing 12
chr4_-_119322128 0.14 ENST00000274024.4
FABP2
fatty acid binding protein 2
chr6_+_26087281 0.13 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
HFE
homeostatic iron regulator
chr15_+_21579912 0.13 ENST00000628444.1
LINC02203
long intergenic non-protein coding RNA 2203
chr19_-_14848922 0.13 ENST00000641129.1
OR7A10
olfactory receptor family 7 subfamily A member 10
chr11_-_72112068 0.13 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
ANAPC15
anaphase promoting complex subunit 15
chr2_+_112542413 0.13 ENST00000417433.6
ENST00000263331.10
POLR1B
RNA polymerase I subunit B
chr7_+_107583919 0.13 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr1_+_207325629 0.13 ENST00000618707.2
CD55
CD55 molecule (Cromer blood group)
chr2_+_87338511 0.13 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr7_+_118224654 0.13 ENST00000265224.9
ENST00000486422.1
ENST00000417525.5
ANKRD7
ankyrin repeat domain 7
chr12_+_26195647 0.13 ENST00000535504.1
SSPN
sarcospan
chr12_-_9869345 0.13 ENST00000228438.3
CLEC2B
C-type lectin domain family 2 member B
chr6_+_37929959 0.12 ENST00000373389.5
ZFAND3
zinc finger AN1-type containing 3
chr2_-_88979016 0.12 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr10_+_113126670 0.12 ENST00000369389.6
TCF7L2
transcription factor 7 like 2
chr22_-_39893755 0.12 ENST00000325157.7
ENTHD1
ENTH domain containing 1
chr1_-_66801276 0.11 ENST00000304526.3
INSL5
insulin like 5
chr6_+_26087417 0.11 ENST00000357618.10
ENST00000309234.10
HFE
homeostatic iron regulator
chr1_-_230869564 0.11 ENST00000470540.5
C1orf198
chromosome 1 open reading frame 198
chr19_+_55769118 0.11 ENST00000341750.5
RFPL4AL1
ret finger protein like 4A like 1
chr11_-_107858777 0.11 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr6_+_154039333 0.11 ENST00000428397.6
OPRM1
opioid receptor mu 1
chr1_-_207052980 0.11 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr17_-_40665121 0.11 ENST00000394052.5
KRT222
keratin 222
chr17_+_18183052 0.11 ENST00000541285.1
ALKBH5
alkB homolog 5, RNA demethylase
chr12_-_118359639 0.11 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAOK3
TAO kinase 3
chr1_-_23799533 0.11 ENST00000429356.5
GALE
UDP-galactose-4-epimerase
chr8_-_673547 0.10 ENST00000522893.1
ERICH1
glutamate rich 1
chr4_-_46124046 0.10 ENST00000295452.5
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
chr16_+_31259922 0.10 ENST00000648685.1
ENST00000544665.9
ITGAM
integrin subunit alpha M
chr14_+_32329341 0.10 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr4_+_87799546 0.10 ENST00000226284.7
IBSP
integrin binding sialoprotein
chr15_+_58410543 0.10 ENST00000356113.10
ENST00000414170.7
LIPC
lipase C, hepatic type
chr11_+_35180279 0.10 ENST00000531873.5
CD44
CD44 molecule (Indian blood group)
chr11_-_72112669 0.09 ENST00000545944.5
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr1_-_201171545 0.09 ENST00000367333.6
TMEM9
transmembrane protein 9
chr10_-_49188380 0.09 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
TMEM273
transmembrane protein 273
chr12_-_8066331 0.09 ENST00000546241.1
ENST00000307637.5
C3AR1
complement C3a receptor 1
chr12_+_6904733 0.09 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
LRRC23
leucine rich repeat containing 23
chr3_-_101320558 0.09 ENST00000193391.8
IMPG2
interphotoreceptor matrix proteoglycan 2
chr19_-_40413364 0.09 ENST00000291825.11
ENST00000324001.8
PRX
periaxin
chr3_-_20012250 0.09 ENST00000389050.5
PP2D1
protein phosphatase 2C like domain containing 1
chr6_-_110179995 0.09 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASF1
WASP family member 1
chr3_-_64019334 0.09 ENST00000480205.5
PSMD6
proteasome 26S subunit, non-ATPase 6
chr3_+_51817596 0.09 ENST00000456080.5
ENSG00000285749.2
novel protein
chr11_+_57712574 0.09 ENST00000278422.9
ENST00000378312.8
TMX2
thioredoxin related transmembrane protein 2
chr12_+_28257195 0.09 ENST00000381259.5
CCDC91
coiled-coil domain containing 91
chr2_-_169031317 0.09 ENST00000650372.1
ABCB11
ATP binding cassette subfamily B member 11
chr9_-_28670285 0.09 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr16_-_81220370 0.09 ENST00000337114.8
PKD1L2
polycystin 1 like 2 (gene/pseudogene)
chr8_+_49911604 0.08 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
SNTG1
syntrophin gamma 1
chr19_+_42076129 0.08 ENST00000359044.5
ZNF574
zinc finger protein 574
chr11_-_72112750 0.08 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
ANAPC15
anaphase promoting complex subunit 15
chr2_-_219399981 0.08 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
DNPEP
aspartyl aminopeptidase
chr7_-_44541318 0.08 ENST00000381160.8
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr5_-_95081482 0.08 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr8_+_49911396 0.08 ENST00000642720.2
SNTG1
syntrophin gamma 1
chr1_-_23799561 0.08 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr2_+_186506713 0.08 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr12_-_23584600 0.08 ENST00000396007.6
SOX5
SRY-box transcription factor 5
chr12_-_122500520 0.08 ENST00000540586.1
ENST00000543897.5
ZCCHC8
zinc finger CCHC-type containing 8
chr11_-_124315099 0.08 ENST00000641897.1
OR8D1
olfactory receptor family 8 subfamily D member 1
chr17_-_59151794 0.07 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr16_+_15395745 0.07 ENST00000287594.7
ENST00000396385.4
ENST00000568766.1
MPV17L
ENSG00000261130.5
MPV17 mitochondrial inner membrane protein like
novel protein
chrX_-_152709260 0.07 ENST00000535353.3
ENST00000638741.1
ENST00000640702.1
CSAG2
CSAG family member 2
chr2_+_233917371 0.07 ENST00000324695.9
ENST00000433712.6
TRPM8
transient receptor potential cation channel subfamily M member 8
chr1_-_150765785 0.07 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
CTSS
cathepsin S
chr3_+_195720867 0.07 ENST00000436408.6
MUC20
mucin 20, cell surface associated
chr12_+_16347102 0.07 ENST00000536371.5
ENST00000010404.6
MGST1
microsomal glutathione S-transferase 1
chr11_+_112025968 0.07 ENST00000680411.1
DLAT
dihydrolipoamide S-acetyltransferase
chr14_+_39267377 0.07 ENST00000556148.5
ENST00000348007.7
MIA2
MIA SH3 domain ER export factor 2
chrX_-_72239022 0.07 ENST00000373657.2
ENST00000334463.4
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr11_+_102047422 0.06 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
CFAP300
cilia and flagella associated protein 300
chr1_+_151762899 0.06 ENST00000635322.1
ENST00000321531.10
OAZ3
ornithine decarboxylase antizyme 3
chr2_-_89085787 0.06 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr6_+_110180418 0.06 ENST00000368930.5
ENST00000307731.2
CDC40
cell division cycle 40
chr2_+_165239388 0.06 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
SCN2A
sodium voltage-gated channel alpha subunit 2
chr12_+_8513499 0.06 ENST00000299665.3
CLEC4D
C-type lectin domain family 4 member D
chr19_-_9107475 0.06 ENST00000641081.1
OR7G2
olfactory receptor family 7 subfamily G member 2
chr11_-_102843597 0.06 ENST00000299855.10
MMP3
matrix metallopeptidase 3
chr17_+_58169401 0.06 ENST00000641866.1
OR4D2
olfactory receptor family 4 subfamily D member 2
chr17_+_29941605 0.05 ENST00000394835.7
EFCAB5
EF-hand calcium binding domain 5
chr3_-_57226344 0.05 ENST00000495160.2
HESX1
HESX homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.2 3.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.7 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.5 GO:0098582 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.9 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.4 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.2 GO:1904440 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 2.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.2 GO:0032761 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.1 1.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 1.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0015847 putrescine transport(GO:0015847)
0.0 1.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0051918 negative regulation of smooth muscle cell apoptotic process(GO:0034392) negative regulation of fibrinolysis(GO:0051918)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 1.7 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.3 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0060187 cell pole(GO:0060187)
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 2.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 1.7 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 0.9 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.6 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 1.2 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.3 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 1.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism