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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for CDX2

Z-value: 0.86

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Transcription factors associated with CDX2

Gene Symbol Gene ID Gene Info
ENSG00000165556.10 caudal type homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX2hg38_v1_chr13_-_27969295_279693500.667.4e-02Click!

Activity profile of CDX2 motif

Sorted Z-values of CDX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_106693838 1.47 ENST00000324342.7
ring finger protein 128
chr5_+_36608146 1.33 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr1_+_13585453 1.18 ENST00000487038.5
ENST00000475043.5
podoplanin
chr12_-_52434363 1.10 ENST00000252245.6
keratin 75
chr7_-_41703062 1.09 ENST00000242208.5
inhibin subunit beta A
chr5_+_36606355 0.91 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr3_-_172523460 0.81 ENST00000420541.6
TNF superfamily member 10
chr3_-_172523423 0.80 ENST00000241261.7
TNF superfamily member 10
chr7_-_143408848 0.79 ENST00000275815.4
EPH receptor A1
chr5_+_140882116 0.76 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chr2_-_216013582 0.73 ENST00000620139.4
melanoregulin
chr1_+_160400543 0.70 ENST00000368061.3
VANGL planar cell polarity protein 2
chr17_-_41489907 0.64 ENST00000328119.11
keratin 36
chr7_-_16833411 0.62 ENST00000412973.1
anterior gradient 2, protein disulphide isomerase family member
chr7_+_129144691 0.54 ENST00000486685.3
tetraspanin 33
chr18_+_58196736 0.54 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr4_+_95051671 0.54 ENST00000440890.7
bone morphogenetic protein receptor type 1B
chr19_+_14031746 0.52 ENST00000263379.4
interleukin 27 receptor subunit alpha
chr4_-_71784046 0.52 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr10_-_127892930 0.49 ENST00000368671.4
clarin 3
chr10_+_24466487 0.49 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr1_+_24319342 0.46 ENST00000361548.9
grainyhead like transcription factor 3
chr5_-_149063021 0.45 ENST00000515425.6
SH3 domain and tetratricopeptide repeats 2
chr17_-_8119047 0.43 ENST00000318227.4
arachidonate lipoxygenase 3
chr6_+_47698574 0.43 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr8_-_80171496 0.43 ENST00000379096.9
ENST00000518937.6
tumor protein D52
chr6_+_47698538 0.42 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr9_-_83063135 0.36 ENST00000376447.4
RAS and EF-hand domain containing
chr3_+_125969152 0.34 ENST00000251776.8
ENST00000504401.1
rhophilin associated tail protein 1B
chr11_+_63838902 0.33 ENST00000377810.8
microtubule affinity regulating kinase 2
chr8_-_80080816 0.33 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr12_-_18090185 0.33 ENST00000229002.6
ENST00000538724.6
RERG like
chr18_-_55321986 0.32 ENST00000570287.6
transcription factor 4
chrX_+_66164340 0.31 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr8_-_20183127 0.31 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr4_+_94974984 0.30 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr12_+_45292674 0.30 ENST00000679426.1
ENST00000441606.2
anoctamin 6
chr18_-_55510753 0.30 ENST00000543082.5
transcription factor 4
chr8_-_20183090 0.30 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr5_+_122129533 0.29 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr15_-_41544243 0.29 ENST00000567866.5
ENST00000304330.9
ENST00000561603.5
ENST00000566863.1
RNA polymerase II associated protein 1
chrX_+_66164210 0.28 ENST00000343002.7
ENST00000336279.9
hephaestin
chr10_+_84173793 0.27 ENST00000372126.4
chromosome 10 open reading frame 99
chr4_-_76023489 0.27 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr1_-_23559490 0.27 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr8_+_106726012 0.26 ENST00000449762.6
ENST00000297447.10
oxidation resistance 1
chr17_-_82840010 0.26 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr20_+_44355692 0.25 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chrX_-_13319952 0.25 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chr3_-_197184131 0.25 ENST00000452595.5
discs large MAGUK scaffold protein 1
chr22_+_32059165 0.24 ENST00000543737.2
solute carrier family 5 member 1
chr4_-_84499281 0.24 ENST00000295886.5
NK6 homeobox 1
chr5_-_43515128 0.23 ENST00000306862.7
chromosome 5 open reading frame 34
chr11_+_112176364 0.22 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr12_+_1691011 0.21 ENST00000357103.5
adiponectin receptor 2
chr18_-_55321640 0.21 ENST00000637169.2
transcription factor 4
chr8_+_123072667 0.19 ENST00000519418.5
ENST00000287380.6
ENST00000327098.9
ENST00000522420.5
ENST00000521676.5
TBC1 domain family member 31
chr7_+_80133830 0.19 ENST00000648098.1
ENST00000648476.1
ENST00000648412.1
ENST00000648953.1
ENST00000648306.1
ENST00000648832.1
ENST00000648877.1
ENST00000442586.2
ENST00000649487.1
ENST00000649267.1
G protein subunit alpha i1
chr21_-_30829755 0.19 ENST00000621162.1
keratin associated protein 7-1
chr11_+_60280577 0.19 ENST00000679988.1
membrane spanning 4-domains A4A
chr6_-_143450662 0.19 ENST00000237283.9
adenosine deaminase tRNA specific 2
chr6_+_124983356 0.19 ENST00000519799.5
ENST00000368414.6
ENST00000359704.2
ring finger protein 217
chr7_-_25228485 0.18 ENST00000222674.2
neuropeptide VF precursor
chr9_-_130939205 0.18 ENST00000372338.9
fibrinogen C domain containing 1
chr1_-_53889766 0.18 ENST00000371399.5
ENST00000072644.7
Yip1 domain family member 1
chr1_+_92168915 0.18 ENST00000637221.2
BTB domain containing 8
chr10_-_125881282 0.18 ENST00000284690.4
DEAH-box helicase 32 (putative)
chr3_-_185821092 0.18 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr14_+_56117702 0.18 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr17_-_29761390 0.17 ENST00000324677.12
slingshot protein phosphatase 2
chr8_+_106726115 0.17 ENST00000521592.5
oxidation resistance 1
chr3_-_108953870 0.17 ENST00000261047.8
guanylate cyclase activator 1C
chr6_+_29301701 0.17 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr12_-_21774688 0.17 ENST00000240662.3
potassium inwardly rectifying channel subfamily J member 8
chr12_-_10810168 0.17 ENST00000240691.4
taste 2 receptor member 9
chr7_-_111392915 0.16 ENST00000450877.5
inner mitochondrial membrane peptidase subunit 2
chr3_-_123992046 0.16 ENST00000467907.5
ENST00000459660.5
ENST00000495093.1
ENST00000460743.5
ENST00000405845.7
ENST00000484329.1
ENST00000479867.1
ENST00000496145.5
rhophilin associated tail protein 1
chr4_+_186227501 0.16 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr2_-_51032151 0.15 ENST00000628515.2
neurexin 1
chr11_-_5154757 0.15 ENST00000380367.3
olfactory receptor family 52 subfamily A member 1
chr11_+_60280531 0.15 ENST00000532114.6
membrane spanning 4-domains A4A
chr2_+_27217361 0.15 ENST00000264705.9
ENST00000403525.5
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr17_-_40665121 0.15 ENST00000394052.5
keratin 222
chr6_-_29375291 0.15 ENST00000396806.3
olfactory receptor family 12 subfamily D member 3
chr3_+_57890011 0.14 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr9_-_101442403 0.14 ENST00000648758.1
aldolase, fructose-bisphosphate B
chr3_-_108953762 0.14 ENST00000393963.7
ENST00000471108.1
guanylate cyclase activator 1C
chr3_+_141262614 0.14 ENST00000504264.5
2-phosphoxylose phosphatase 1
chr4_+_71062642 0.14 ENST00000649996.1
solute carrier family 4 member 4
chr10_+_75111476 0.13 ENST00000671730.1
sterile alpha motif domain containing 8
chr21_-_26090035 0.13 ENST00000448850.5
amyloid beta precursor protein
chr16_-_21652598 0.13 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr12_-_21775045 0.13 ENST00000667884.1
potassium inwardly rectifying channel subfamily J member 8
chr5_+_62578810 0.13 ENST00000334994.6
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr15_+_22458903 0.12 ENST00000620691.4
golgin A6 family like 22
chr1_+_220094086 0.12 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr16_-_1884231 0.12 ENST00000563416.3
ENST00000633813.1
ENST00000470044.5
long intergenic non-protein coding RNA 254
meiosis specific with OB-fold
chr3_+_125969172 0.12 ENST00000514116.6
ENST00000513830.5
rhophilin associated tail protein 1B
chr19_+_48393657 0.12 ENST00000263269.4
glutamate ionotropic receptor NMDA type subunit 2D
chr1_-_28058087 0.12 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chr16_+_4474690 0.12 ENST00000575051.5
ENST00000406590.6
heme oxygenase 2
chr15_-_20541800 0.12 ENST00000619213.1
golgin A6 family like 6
chr16_+_68085861 0.11 ENST00000570212.5
ENST00000562926.5
nuclear factor of activated T cells 3
chr9_-_92293674 0.11 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
isoleucyl-tRNA synthetase 1
chr16_-_20327801 0.11 ENST00000381360.9
glycoprotein 2
chr6_-_27807916 0.11 ENST00000377401.3
H2B clustered histone 13
chr7_-_130440848 0.11 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
centrosomal protein 41
chr10_+_75111595 0.11 ENST00000671800.1
ENST00000542569.6
ENST00000372687.4
sterile alpha motif domain containing 8
chrX_-_15600953 0.11 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
angiotensin I converting enzyme 2
chr4_-_39977836 0.11 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr7_+_130344810 0.11 ENST00000497503.5
ENST00000463587.5
ENST00000461828.5
ENST00000474905.6
ENST00000494311.1
ENST00000466363.6
carboxypeptidase A5
chr17_-_29761415 0.11 ENST00000649863.1
slingshot protein phosphatase 2
chr17_-_40799939 0.10 ENST00000306658.8
keratin 28
chr4_+_70397931 0.10 ENST00000399575.7
opiorphin prepropeptide
chr1_-_86383078 0.10 ENST00000460698.6
outer dense fiber of sperm tails 2 like
chr11_+_55635113 0.10 ENST00000641760.1
olfactory receptor family 4 subfamily P member 4
chr4_-_122456725 0.09 ENST00000226730.5
interleukin 2
chr4_+_154563003 0.09 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr10_+_73744346 0.09 ENST00000345254.9
ENST00000339365.2
SEC24 homolog C, COPII coat complex component
chr16_-_20327426 0.09 ENST00000575582.5
ENST00000341642.9
ENST00000381362.8
ENST00000572347.5
ENST00000572478.5
ENST00000302555.10
glycoprotein 2
chr1_+_248038172 0.09 ENST00000366479.4
olfactory receptor family 2 subfamily L member 2
chr2_+_32165841 0.09 ENST00000357055.7
ENST00000435660.5
ENST00000440718.5
ENST00000379343.6
ENST00000282587.9
ENST00000406369.2
solute carrier family 30 member 6
chr1_+_34176900 0.09 ENST00000488417.2
chromosome 1 open reading frame 94
chr12_+_54284258 0.09 ENST00000677666.1
heterogeneous nuclear ribonucleoprotein A1
chr5_+_87268922 0.09 ENST00000456692.6
ENST00000512763.5
ENST00000506290.1
RAS p21 protein activator 1
chr19_+_4402615 0.09 ENST00000301280.10
chromatin assembly factor 1 subunit A
chr15_+_67521104 0.08 ENST00000342683.6
chromosome 15 open reading frame 61
chr6_+_133953210 0.08 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr14_+_21825453 0.08 ENST00000390432.2
T cell receptor alpha variable 10
chr6_+_143450797 0.08 ENST00000367591.5
ENST00000367592.5
peroxisomal biogenesis factor 3
chr2_-_51032091 0.08 ENST00000637511.1
ENST00000405472.7
ENST00000405581.3
ENST00000401669.7
neurexin 1
chr6_+_27808163 0.08 ENST00000358739.4
H2A clustered histone 13
chr12_+_25052634 0.07 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chr8_-_13514887 0.07 ENST00000511869.1
DLC1 Rho GTPase activating protein
chr2_-_208146150 0.07 ENST00000260988.5
crystallin gamma B
chr8_-_142777802 0.07 ENST00000621401.4
Ly6/neurotoxin 1
chr3_-_53891836 0.07 ENST00000495461.6
ENST00000541726.5
selenoprotein K
chrX_+_65488735 0.07 ENST00000338957.4
zinc finger CCCH-type containing 12B
chr18_+_63542365 0.07 ENST00000269491.6
ENST00000382768.2
serpin family B member 12
chr20_+_2295994 0.06 ENST00000381458.6
transglutaminase 3
chr6_+_118548289 0.06 ENST00000357525.6
phospholamban
chr11_-_31804067 0.06 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
paired box 6
chr15_-_55249029 0.06 ENST00000566877.5
RAB27A, member RAS oncogene family
chr11_+_58622659 0.06 ENST00000361987.6
ciliary neurotrophic factor
chr3_-_51779187 0.06 ENST00000398780.5
ENST00000668964.1
ENST00000667863.2
ENST00000647442.1
IQ motif containing F6
chr1_-_110519175 0.05 ENST00000369771.4
potassium voltage-gated channel subfamily A member 10
chr17_+_27609836 0.05 ENST00000582410.5
kinase suppressor of ras 1
chr6_-_22302797 0.05 ENST00000651757.1
prolactin
chr1_-_186461089 0.05 ENST00000391997.3
phosducin
chr1_+_178725147 0.05 ENST00000367634.6
Ral GEF with PH domain and SH3 binding motif 2
chr3_-_65622073 0.05 ENST00000621418.4
ENST00000611645.4
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr10_+_13610047 0.05 ENST00000601460.5
novel protein
chr4_-_68670648 0.05 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr17_+_59940908 0.05 ENST00000591035.1
novel protein
chr6_+_27815010 0.04 ENST00000621112.2
H2B clustered histone 14
chr4_+_185395979 0.04 ENST00000507753.1
ankyrin repeat domain 37
chr2_+_218782138 0.04 ENST00000258415.9
cytochrome P450 family 27 subfamily A member 1
chr6_+_12957301 0.04 ENST00000676234.1
phosphatase and actin regulator 1
chr4_-_168318770 0.04 ENST00000680771.1
ENST00000514995.2
DExD/H-box helicase 60
chr8_+_75539862 0.04 ENST00000396423.4
hepatocyte nuclear factor 4 gamma
chr18_+_3252208 0.04 ENST00000578562.6
myosin light chain 12A
chr20_-_7940444 0.04 ENST00000378789.4
hydroxyacid oxidase 1
chr3_+_112990956 0.04 ENST00000383678.8
ENST00000383677.7
ENST00000619116.4
GTP binding protein 8 (putative)
chr22_+_50170720 0.04 ENST00000159647.9
ENST00000395842.3
pannexin 2
chr8_+_75539893 0.03 ENST00000674002.1
hepatocyte nuclear factor 4 gamma
chr17_-_48728705 0.03 ENST00000290295.8
homeobox B13
chr11_-_60906564 0.03 ENST00000541371.5
ENST00000227524.9
pre-mRNA processing factor 19
chr16_+_66579448 0.03 ENST00000379486.6
ENST00000268595.3
CKLF like MARVEL transmembrane domain containing 2
chr22_-_37844308 0.03 ENST00000411961.6
ENST00000434930.1
ENST00000215941.9
ankyrin repeat domain 54
chr11_+_60378494 0.03 ENST00000534016.5
membrane spanning 4-domains A7
chr4_-_163613505 0.03 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr12_+_130162456 0.03 ENST00000539839.1
ENST00000229030.5
frizzled class receptor 10
chr6_+_12957347 0.03 ENST00000482982.2
phosphatase and actin regulator 1
chr4_+_70383123 0.03 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr6_-_27814757 0.03 ENST00000333151.5
H2A clustered histone 14
chr2_-_169031317 0.02 ENST00000650372.1
ATP binding cassette subfamily B member 11
chr14_-_56805648 0.02 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
orthodenticle homeobox 2
chr11_-_13496018 0.02 ENST00000529816.1
parathyroid hormone
chr20_+_4721901 0.02 ENST00000305817.3
prion like protein doppel
chr4_-_168318743 0.02 ENST00000393743.8
DExD/H-box helicase 60
chr1_-_7940825 0.02 ENST00000377507.8
TNF receptor superfamily member 9
chr13_-_45201027 0.02 ENST00000379108.2
potassium channel tetramerization domain containing 4
chr6_+_111087495 0.02 ENST00000612036.4
ENST00000368851.10
solute carrier family 16 member 10
chr1_+_220690354 0.02 ENST00000294889.6
chromosome 1 open reading frame 115
chr16_+_31459950 0.02 ENST00000564900.1
armadillo repeat containing 5
chr1_+_151766655 0.02 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr6_+_25754699 0.02 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr2_+_186506713 0.02 ENST00000445547.1
zinc finger CCCH-type containing 15
chr2_-_201769759 0.01 ENST00000680163.1
ENST00000680188.1
ENST00000679550.1
alsin Rho guanine nucleotide exchange factor ALS2
chr11_+_22666604 0.01 ENST00000454584.6
growth arrest specific 2
chr1_-_151763334 0.01 ENST00000481777.5
ENST00000368829.3
ENST00000368830.8
mitochondrial ribosomal protein L9
chr2_-_113052867 0.01 ENST00000259213.9
ENST00000327407.2
interleukin 36 beta
chr16_+_72056153 0.01 ENST00000576168.6
ENST00000567185.7
ENST00000567612.2
haptoglobin
chr12_-_55296569 0.01 ENST00000358433.3
olfactory receptor family 6 subfamily C member 6
chr2_-_240820945 0.01 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
kinesin family member 1A
chr9_-_28670285 0.00 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
leucine rich repeat and Ig domain containing 2
chr2_+_37950432 0.00 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
regulator of microtubule dynamics 2
chr11_-_13495984 0.00 ENST00000282091.6
parathyroid hormone
chr9_+_131190119 0.00 ENST00000483497.6
nucleoporin 214

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.4 1.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 0.7 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.2 2.2 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 1.5 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.6 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 0.8 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.3 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.2 GO:0016116 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 1.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.5 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0010819 regulation of T cell chemotaxis(GO:0010819) positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0014005 astrocyte activation involved in immune response(GO:0002265) microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1901876 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.8 GO:0032402 melanosome transport(GO:0032402)
0.0 0.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:1903286 hard palate development(GO:0060022) regulation of potassium ion import(GO:1903286) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0046666 retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.2 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.2 2.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.3 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.0 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells