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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for CEBPA

Z-value: 1.45

Motif logo

Transcription factors associated with CEBPA

Gene Symbol Gene ID Gene Info
ENSG00000245848.3 CCAAT enhancer binding protein alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPAhg38_v1_chr19_-_33302524_333025420.452.6e-01Click!

Activity profile of CEBPA motif

Sorted Z-values of CEBPA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102798148 4.07 ENST00000315274.7
matrix metallopeptidase 1
chr20_-_45254556 3.97 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr18_+_63887698 2.48 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr19_-_35501878 2.17 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr19_-_35513641 2.07 ENST00000339686.8
ENST00000447113.6
dermokine
chr2_-_112836702 1.98 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr1_+_152514474 1.97 ENST00000368790.4
cysteine rich C-terminal 1
chr11_-_18248662 1.93 ENST00000256733.9
serum amyloid A2
chr11_+_18266254 1.83 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr12_-_122703346 1.72 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr4_-_10021490 1.70 ENST00000264784.8
solute carrier family 2 member 9
chr11_-_18248632 1.53 ENST00000524555.3
ENST00000528349.5
ENST00000526900.1
ENST00000529528.5
ENST00000414546.6
SAA2-SAA4 readthrough
serum amyloid A2
chr13_-_20230970 1.51 ENST00000644667.1
ENST00000646108.1
gap junction protein beta 6
chr12_+_29223659 1.51 ENST00000182377.8
fatty acyl-CoA reductase 2
chr9_+_128149447 1.37 ENST00000277480.7
ENST00000372998.1
lipocalin 2
chr12_-_95116967 1.37 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr19_-_6720641 1.36 ENST00000245907.11
complement C3
chr12_+_29223730 1.29 ENST00000547116.5
fatty acyl-CoA reductase 2
chr2_-_46462 1.26 ENST00000327669.5
family with sequence similarity 110 member C
chr10_-_114684612 1.25 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr10_-_114684457 1.21 ENST00000392955.7
actin binding LIM protein 1
chr6_-_41163182 1.20 ENST00000338469.3
triggering receptor expressed on myeloid cells 2
chr6_-_41163103 1.03 ENST00000373122.8
ENST00000373113.8
triggering receptor expressed on myeloid cells 2
chr16_-_68236069 1.02 ENST00000473183.7
ENST00000565858.5
epithelial splicing regulatory protein 2
chr12_-_122716790 1.01 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr1_-_186680411 0.97 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr2_-_31414694 0.95 ENST00000379416.4
xanthine dehydrogenase
chr1_+_196774813 0.94 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr1_-_54801290 0.93 ENST00000371276.9
tetratricopeptide repeat domain 22
chr17_-_78128630 0.90 ENST00000306591.11
transmembrane channel like 6
chr1_+_101237009 0.90 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr10_-_44978789 0.87 ENST00000448778.1
ENST00000298295.4
DEPP1 autophagy regulator
chr12_-_85836372 0.86 ENST00000361228.5
Ras association domain family member 9
chr1_+_101238090 0.85 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr7_+_26152188 0.84 ENST00000056233.4
nuclear factor, erythroid 2 like 3
chr6_+_106086316 0.84 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr2_+_101991953 0.83 ENST00000332549.8
interleukin 1 receptor type 2
chr19_-_54173151 0.83 ENST00000619895.5
transmembrane channel like 4
chr6_+_30880780 0.82 ENST00000460944.6
ENST00000324771.12
discoidin domain receptor tyrosine kinase 1
chr11_-_112164080 0.81 ENST00000528832.1
ENST00000280357.12
interleukin 18
chr11_-_112164056 0.80 ENST00000524595.5
interleukin 18
chr7_+_18496162 0.77 ENST00000406072.5
histone deacetylase 9
chr10_+_95755737 0.76 ENST00000543964.6
ectonucleoside triphosphate diphosphohydrolase 1
chr8_+_18391276 0.75 ENST00000286479.4
ENST00000520116.1
N-acetyltransferase 2
chr19_-_54173190 0.73 ENST00000617472.4
transmembrane channel like 4
chr13_+_77535669 0.71 ENST00000535157.5
sciellin
chr5_-_140633167 0.70 ENST00000302014.11
CD14 molecule
chr13_+_77535681 0.69 ENST00000349847.4
sciellin
chr13_+_77535742 0.69 ENST00000377246.7
sciellin
chr11_+_118077067 0.69 ENST00000522307.5
ENST00000523251.5
ENST00000437212.8
ENST00000522824.5
ENST00000522151.5
transmembrane serine protease 4
chr11_+_118077009 0.68 ENST00000616579.4
ENST00000534111.5
transmembrane serine protease 4
chr21_+_42199686 0.65 ENST00000398457.6
ATP binding cassette subfamily G member 1
chr1_-_113887375 0.64 ENST00000471267.1
ENST00000393320.3
BCL2 like 15
chr12_+_100794769 0.64 ENST00000392977.8
ENST00000546991.1
ENST00000392979.7
anoctamin 4
chr14_+_96256194 0.64 ENST00000216629.11
ENST00000553356.1
bradykinin receptor B1
chr3_-_27456743 0.63 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
solute carrier family 4 member 7
chr6_+_47698574 0.62 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr6_+_47698538 0.61 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr1_+_111227699 0.60 ENST00000369748.9
chitinase 3 like 2
chr1_+_111227610 0.60 ENST00000369744.6
chitinase 3 like 2
chr1_-_153057504 0.59 ENST00000392653.3
small proline rich protein 2A
chr14_+_22314435 0.58 ENST00000390467.3
T cell receptor alpha variable 40
chr2_-_18589536 0.58 ENST00000416783.1
ENST00000359846.6
ENST00000304081.8
ENST00000532967.5
ENST00000444297.2
5'-nucleotidase, cytosolic IB
NT5C1B-RDH14 readthrough
chr19_+_49581304 0.58 ENST00000246794.10
proline rich and Gla domain 2
chr19_+_41797147 0.57 ENST00000596544.1
CEA cell adhesion molecule 3
chr21_-_44928711 0.57 ENST00000517563.5
integrin subunit beta 2
chr1_+_196888014 0.57 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr19_-_54364983 0.55 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chr9_-_39288138 0.55 ENST00000297668.10
contactin associated protein family member 3
chr16_+_82056423 0.55 ENST00000568090.5
hydroxysteroid 17-beta dehydrogenase 2
chr18_-_50195138 0.53 ENST00000285039.12
myosin VB
chrX_+_105948429 0.52 ENST00000540278.1
Nik related kinase
chr18_-_63661884 0.50 ENST00000332821.8
ENST00000283752.10
serpin family B member 3
chr17_-_4736380 0.50 ENST00000576153.5
C-X-C motif chemokine ligand 16
chr14_+_21042352 0.50 ENST00000298690.5
ribonuclease A family member 7
chr12_+_41437680 0.49 ENST00000649474.1
ENST00000539469.6
ENST00000298919.7
PDZ domain containing ring finger 4
chr8_+_97887903 0.48 ENST00000520016.5
matrilin 2
chr4_+_88378733 0.48 ENST00000273960.7
ENST00000380265.9
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr12_-_94650506 0.48 ENST00000261226.9
transmembrane and coiled-coil domain family 3
chr9_-_114806031 0.48 ENST00000374045.5
TNF superfamily member 15
chr12_+_19205294 0.47 ENST00000424268.5
pleckstrin homology domain containing A5
chr2_+_230759918 0.47 ENST00000614925.1
calcium binding protein 39
chr15_+_88639009 0.46 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr4_+_88378842 0.45 ENST00000264346.12
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr8_+_27491125 0.45 ENST00000517536.5
ENST00000521400.6
ENST00000521780.5
ENST00000380476.7
ENST00000518379.5
ENST00000521684.1
epoxide hydrolase 2
chr11_+_7576408 0.45 ENST00000533792.5
PPFIA binding protein 2
chr4_-_138242325 0.44 ENST00000280612.9
solute carrier family 7 member 11
chr18_-_63644250 0.43 ENST00000341074.10
ENST00000436264.1
serpin family B member 4
chr8_+_117520832 0.42 ENST00000522839.1
mediator complex subunit 30
chr6_+_130018565 0.41 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr8_-_18083184 0.40 ENST00000636269.1
N-acylsphingosine amidohydrolase 1
chr3_+_124584625 0.39 ENST00000291478.9
ENST00000682363.1
ENST00000454902.1
kalirin RhoGEF kinase
chr10_+_95755652 0.39 ENST00000371207.8
ectonucleoside triphosphate diphosphohydrolase 1
chr3_+_49803212 0.39 ENST00000333323.6
inka box actin regulator 1
chr15_+_88638947 0.38 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr12_-_46268989 0.38 ENST00000549049.5
ENST00000439706.5
ENST00000398637.10
solute carrier family 38 member 1
chr3_+_119173564 0.38 ENST00000264234.8
ENST00000479520.5
ENST00000494855.5
uroplakin 1B
chr5_+_147878703 0.37 ENST00000296694.5
secretoglobin family 3A member 2
chr19_+_45001430 0.37 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr14_-_81427390 0.37 ENST00000555447.5
stonin 2
chr22_-_32464440 0.37 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr1_-_206921867 0.36 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr3_-_112499358 0.36 ENST00000383680.4
B and T lymphocyte associated
chr19_-_54364908 0.36 ENST00000391742.7
leukocyte associated immunoglobulin like receptor 1
chr5_-_140633690 0.36 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr7_+_107583919 0.36 ENST00000491150.5
B cell receptor associated protein 29
chr14_+_24070837 0.36 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr18_-_55403682 0.36 ENST00000564228.5
ENST00000630828.2
transcription factor 4
chr8_+_117520696 0.35 ENST00000297347.7
mediator complex subunit 30
chr19_+_44891206 0.34 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
translocase of outer mitochondrial membrane 40
chr17_-_78128778 0.34 ENST00000589553.5
transmembrane channel like 6
chr14_-_22815856 0.34 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr18_+_10454584 0.34 ENST00000355285.10
APC down-regulated 1
chr14_-_22815801 0.34 ENST00000397532.9
solute carrier family 7 member 7
chr10_+_93757831 0.34 ENST00000629035.2
leucine rich glioma inactivated 1
chr1_-_36482904 0.34 ENST00000373106.6
colony stimulating factor 3 receptor
chr6_-_53545091 0.33 ENST00000650454.1
glutamate-cysteine ligase catalytic subunit
chr10_+_93757857 0.33 ENST00000478763.2
ENST00000371418.9
ENST00000630184.2
ENST00000630047.2
ENST00000637689.1
leucine rich glioma inactivated 1
chr12_+_20810698 0.33 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr7_-_83162899 0.32 ENST00000423517.6
piccolo presynaptic cytomatrix protein
chr3_+_48223325 0.32 ENST00000296435.2
cathelicidin antimicrobial peptide
chr3_-_123620496 0.32 ENST00000578202.1
myosin light chain kinase
chr3_+_119186716 0.32 ENST00000460625.1
uroplakin 1B
chr3_-_112975018 0.32 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr11_-_101583985 0.31 ENST00000344327.8
transient receptor potential cation channel subfamily C member 6
chr12_+_77830886 0.31 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr7_+_18496269 0.31 ENST00000432645.6
histone deacetylase 9
chr6_-_30075767 0.31 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr1_+_107139996 0.31 ENST00000370073.6
ENST00000370074.8
netrin G1
chr3_+_48223479 0.31 ENST00000652295.2
cathelicidin antimicrobial peptide
chr17_+_58238426 0.31 ENST00000421678.6
ENST00000262290.9
ENST00000543544.5
lactoperoxidase
chr10_-_112183698 0.31 ENST00000369425.5
ENST00000348367.9
glycerol-3-phosphate acyltransferase, mitochondrial
chr3_-_123620571 0.30 ENST00000583087.5
myosin light chain kinase
chr9_-_42129125 0.30 ENST00000617422.4
ENST00000612828.4
ENST00000341990.8
ENST00000377561.7
ENST00000276974.7
contactin associated protein family member 3B
chr14_+_22271921 0.29 ENST00000390464.2
T cell receptor alpha variable 38-1
chr3_-_47475811 0.29 ENST00000265565.10
ENST00000428413.5
SREBF chaperone
chr19_-_55738374 0.29 ENST00000590200.1
ENST00000332836.7
NLR family pyrin domain containing 9
chr2_-_74507664 0.29 ENST00000233630.11
polycomb group ring finger 1
chrX_+_16123544 0.29 ENST00000380289.3
gastrin releasing peptide receptor
chr1_-_153312919 0.28 ENST00000683862.1
peptidoglycan recognition protein 3
chr2_+_71453538 0.28 ENST00000258104.8
dysferlin
chr4_-_89835617 0.28 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr11_-_59212869 0.28 ENST00000361050.4
macrophage expressed 1
chrX_-_139832235 0.28 ENST00000327569.7
ENST00000361648.6
ATPase phospholipid transporting 11C
chr1_+_247416149 0.28 ENST00000366497.6
ENST00000391828.8
NLR family pyrin domain containing 3
chr3_+_141228721 0.28 ENST00000505013.5
2-phosphoxylose phosphatase 1
chr12_-_54364467 0.28 ENST00000267015.4
ENST00000551809.1
G protein-coupled receptor 84
chr3_-_120682215 0.28 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr16_-_58295019 0.28 ENST00000567164.6
ENST00000219301.8
ENST00000569727.1
serine protease 54
chr1_-_153348825 0.28 ENST00000368739.3
ENST00000359650.10
peptidoglycan recognition protein 4
chr1_+_206897435 0.27 ENST00000391929.7
ENST00000294984.7
ENST00000611909.4
ENST00000367093.3
interleukin 24
chr12_+_20368495 0.27 ENST00000359062.4
phosphodiesterase 3A
chr7_+_123601836 0.27 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr3_-_112974912 0.27 ENST00000440122.6
ENST00000490004.1
CD200 receptor 1
chr11_-_57427474 0.26 ENST00000533235.5
ENST00000526621.5
ENST00000352187.5
solute carrier family 43 member 3
chr1_-_67054100 0.26 ENST00000235345.6
solute carrier family 35 member D1
chr1_-_206921987 0.26 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr12_+_12813316 0.26 ENST00000352940.8
ENST00000358007.7
ENST00000544400.1
DEAD-box helicase 47
chr19_+_44643902 0.26 ENST00000403059.8
ENST00000425690.8
PVR cell adhesion molecule
chr6_-_134950081 0.26 ENST00000367847.2
ENST00000265605.7
ENST00000367845.6
aldehyde dehydrogenase 8 family member A1
chr9_+_27524285 0.26 ENST00000276943.3
interferon kappa
chr17_+_59209867 0.26 ENST00000578922.1
ENST00000300917.10
SMG8 nonsense mediated mRNA decay factor
chr4_+_41935114 0.25 ENST00000508448.5
ENST00000513702.5
ENST00000325094.9
transmembrane protein 33
chr3_-_197573323 0.25 ENST00000358186.6
ENST00000431056.5
3-hydroxybutyrate dehydrogenase 1
chr1_-_25859352 0.25 ENST00000374298.4
ENST00000538789.5
aurora kinase A and ninein interacting protein
chr1_+_7784411 0.25 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chr10_-_60141004 0.25 ENST00000355288.6
ankyrin 3
chr12_+_55362975 0.25 ENST00000641576.1
olfactory receptor family 6 subfamily C member 75
chr4_-_152352800 0.25 ENST00000393956.9
F-box and WD repeat domain containing 7
chr6_-_32589833 0.24 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr4_+_73740541 0.24 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr14_-_22815421 0.24 ENST00000674313.1
ENST00000555959.1
solute carrier family 7 member 7
chr1_-_46604214 0.24 ENST00000371946.9
ENST00000428112.7
ENST00000529170.6
ENST00000371945.10
MAPK interacting serine/threonine kinase 1
chr11_-_128867364 0.23 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chr19_-_54364863 0.23 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr6_+_143864458 0.23 ENST00000237275.9
zinc finger C2HC-type containing 1B
chr5_+_141051374 0.23 ENST00000306549.6
protocadherin beta 1
chr19_-_43204223 0.23 ENST00000599746.5
pregnancy specific beta-1-glycoprotein 4
chr11_-_123741614 0.23 ENST00000526252.5
ENST00000530393.6
ENST00000533463.5
ENST00000336139.8
ENST00000529691.1
ENST00000528306.5
zinc finger protein 202
chr3_-_143848442 0.23 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr5_-_146105575 0.23 ENST00000311450.9
PLAC8 like 1
chr3_+_48241046 0.23 ENST00000427617.6
ENST00000412564.5
ENST00000354698.8
ENST00000440261.6
zinc finger protein 589
chr11_-_128867268 0.23 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr12_-_122730828 0.23 ENST00000432564.3
hydroxycarboxylic acid receptor 1
chr11_+_60056587 0.22 ENST00000395032.6
ENST00000358152.6
membrane spanning 4-domains A3
chr11_+_60056653 0.22 ENST00000278865.8
membrane spanning 4-domains A3
chr3_-_50359480 0.22 ENST00000266025.4
transmembrane protein 115
chr19_-_35528221 0.22 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr7_+_140672890 0.22 ENST00000072869.9
aarF domain containing kinase 2
chr13_+_95433593 0.22 ENST00000376873.7
claudin 10
chr17_-_41168219 0.22 ENST00000391356.4
keratin associated protein 4-3
chr1_-_226739271 0.22 ENST00000429204.6
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr19_+_6887560 0.22 ENST00000250572.12
ENST00000381407.9
ENST00000450315.7
ENST00000312053.9
ENST00000381404.8
adhesion G protein-coupled receptor E1
chr16_-_2009797 0.22 ENST00000563630.6
ENST00000562103.2
zinc finger protein 598, E3 ubiquitin ligase
chr3_-_108058361 0.21 ENST00000398258.7
CD47 molecule
chr1_+_166989089 0.21 ENST00000367870.6
maelstrom spermatogenic transposon silencer
chr3_-_191282383 0.21 ENST00000427544.6
urotensin 2B
chr1_-_152325232 0.21 ENST00000368799.2
filaggrin
chr6_+_29942523 0.21 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr6_+_26087417 0.21 ENST00000357618.10
ENST00000309234.10
homeostatic iron regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.7 2.2 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.7 2.0 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.6 1.8 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.5 1.6 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.5 2.8 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5 1.4 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.3 1.7 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 1.0 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of fibroblast growth factor production(GO:0090271) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 0.9 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 0.8 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.3 1.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 0.7 GO:0009720 detection of hormone stimulus(GO:0009720)
0.2 1.1 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.8 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 0.6 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.2 0.5 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2 0.5 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.5 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.1 0.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.4 GO:0002625 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.5 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 4.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.6 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 0.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 3.9 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 1.4 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.5 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 2.5 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:2000724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 1.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.4 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.5 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 1.9 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 3.7 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0046959 habituation(GO:0046959)
0.0 1.0 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) CUT catabolic process(GO:0071034) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) CUT metabolic process(GO:0071043)
0.0 1.6 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.6 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 1.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:1903936 cellular response to salt(GO:1902075) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 5.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.2 GO:0030849 autosome(GO:0030849)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 0.6 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.0 0.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 2.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 3.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 1.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0098576 lumenal side of membrane(GO:0098576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 3.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.3 0.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 0.7 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 1.0 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.2 0.8 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 0.7 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 0.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 1.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.8 GO:0046625 sphingolipid binding(GO:0046625)
0.1 5.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 6.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 3.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0004040 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284) steroid hormone binding(GO:1990239)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 2.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 4.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 4.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis