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Epithelial-Mesenchymal Transition, human (Scheel, 2011)
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Results for CXXC1
Z-value: 0.96
Motif logo
Transcription factors associated with CXXC1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
CXXC1
|
ENSG00000154832.16 | CXXC finger protein 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CXXC1 | hg38_v1_chr18_-_50287570_50287709 | 0.68 | 6.3e-02 | Click! |
Activity profile of CXXC1 motif
Sorted Z-values of CXXC1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of CXXC1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 0.1 | 0.4 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.1 | 0.4 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 0.1 | 0.5 | GO:0051410 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
| 0.1 | 1.2 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.1 | 1.2 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.1 | 0.5 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 0.1 | 0.5 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.1 | 0.1 | GO:0003193 | pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) |
| 0.1 | 0.7 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.1 | 0.9 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 1.4 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.1 | 2.8 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 0.5 | GO:0034959 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.1 | 0.3 | GO:0099553 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
| 0.1 | 1.1 | GO:0030091 | protein repair(GO:0030091) |
| 0.1 | 0.7 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 0.2 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.1 | 0.5 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.1 | 0.4 | GO:0071104 | response to interleukin-9(GO:0071104) |
| 0.1 | 0.3 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.1 | 0.5 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.1 | 0.4 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 0.1 | 0.2 | GO:0045897 | positive regulation of transcription during mitosis(GO:0045897) |
| 0.1 | 0.2 | GO:0006579 | amino-acid betaine catabolic process(GO:0006579) |
| 0.1 | 1.3 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.1 | 0.4 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.1 | 0.4 | GO:0050955 | thermoception(GO:0050955) |
| 0.1 | 0.2 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.1 | 0.4 | GO:0046086 | AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086) |
| 0.1 | 0.2 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
| 0.1 | 0.2 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 0.2 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.1 | 0.2 | GO:0070894 | transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895) |
| 0.1 | 0.2 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.1 | 0.2 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.1 | 0.4 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.1 | 0.2 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.1 | 0.5 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.1 | 0.2 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.1 | 0.3 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.0 | 0.8 | GO:0035791 | platelet-derived growth factor receptor-beta signaling pathway(GO:0035791) |
| 0.0 | 0.2 | GO:0086021 | SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) |
| 0.0 | 0.3 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.0 | 0.2 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.0 | 0.2 | GO:1990169 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.0 | 0.2 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.0 | 0.1 | GO:0021503 | neural fold bending(GO:0021503) |
| 0.0 | 0.4 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.4 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.0 | 0.4 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
| 0.0 | 0.2 | GO:0097210 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.0 | 0.3 | GO:1905123 | regulation of glucosylceramidase activity(GO:1905123) |
| 0.0 | 0.2 | GO:0034239 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) |
| 0.0 | 0.2 | GO:0009236 | cobalamin biosynthetic process(GO:0009236) |
| 0.0 | 0.1 | GO:0042779 | tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) |
| 0.0 | 0.3 | GO:1902957 | negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957) |
| 0.0 | 0.2 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 0.0 | 0.5 | GO:0006547 | histidine metabolic process(GO:0006547) |
| 0.0 | 0.2 | GO:1900737 | negative regulation of phospholipase C activity(GO:1900275) regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737) |
| 0.0 | 0.1 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.0 | 0.2 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.0 | 0.2 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.0 | 0.1 | GO:0019878 | lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) |
| 0.0 | 0.3 | GO:2000467 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.0 | 0.4 | GO:2000580 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.0 | 0.1 | GO:0075071 | autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071) |
| 0.0 | 0.3 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.0 | 0.4 | GO:0010918 | positive regulation of mitochondrial membrane potential(GO:0010918) |
| 0.0 | 0.1 | GO:0061055 | myotome development(GO:0061055) |
| 0.0 | 0.1 | GO:0061580 | colon epithelial cell migration(GO:0061580) |
| 0.0 | 0.2 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.0 | 0.1 | GO:0090274 | regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274) |
| 0.0 | 0.1 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.0 | 0.2 | GO:0019087 | transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860) |
| 0.0 | 0.1 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.0 | 0.2 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.0 | 0.2 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.0 | 0.2 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.0 | 0.4 | GO:0097070 | ductus arteriosus closure(GO:0097070) |
| 0.0 | 0.3 | GO:0046618 | drug export(GO:0046618) |
| 0.0 | 0.1 | GO:0090598 | male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598) |
| 0.0 | 0.7 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.3 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.0 | 0.2 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.0 | 0.2 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 0.2 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.0 | 0.1 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.0 | 0.4 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.0 | 0.4 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.0 | 0.2 | GO:0021678 | third ventricle development(GO:0021678) |
| 0.0 | 0.1 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 0.0 | 0.0 | GO:0021539 | subthalamus development(GO:0021539) |
| 0.0 | 0.5 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.0 | 0.3 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 0.1 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.0 | 0.3 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.0 | 0.8 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.8 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.0 | 0.4 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.0 | 0.1 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.0 | 0.2 | GO:1904386 | response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386) |
| 0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.1 | GO:1990569 | UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569) |
| 0.0 | 0.1 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.0 | 0.1 | GO:2000984 | regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984) |
| 0.0 | 0.5 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.0 | 0.6 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.1 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.0 | 0.1 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.0 | 0.1 | GO:0050720 | interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.0 | 0.1 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.0 | 0.3 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.1 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.0 | 0.1 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.0 | 0.1 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 0.0 | 0.0 | GO:0031990 | mRNA export from nucleus in response to heat stress(GO:0031990) |
| 0.0 | 0.3 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.1 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 0.0 | 0.1 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.0 | 0.1 | GO:0035624 | receptor transactivation(GO:0035624) |
| 0.0 | 0.1 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
| 0.0 | 0.3 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.0 | 0.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.0 | 0.1 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.0 | 0.2 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.0 | 0.1 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 0.0 | 0.1 | GO:0051230 | mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230) |
| 0.0 | 0.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.1 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 0.0 | 0.1 | GO:0042780 | tRNA 3'-end processing(GO:0042780) |
| 0.0 | 0.7 | GO:0071380 | cellular response to prostaglandin E stimulus(GO:0071380) |
| 0.0 | 0.1 | GO:0031999 | negative regulation of fatty acid beta-oxidation(GO:0031999) |
| 0.0 | 0.3 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.1 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 0.0 | 0.1 | GO:0033686 | positive regulation of luteinizing hormone secretion(GO:0033686) |
| 0.0 | 0.4 | GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949) |
| 0.0 | 0.2 | GO:0046061 | dATP catabolic process(GO:0046061) |
| 0.0 | 0.1 | GO:0051311 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 0.0 | 0.3 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.0 | 0.1 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 0.0 | 0.2 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 0.0 | 0.4 | GO:1900025 | negative regulation of substrate adhesion-dependent cell spreading(GO:1900025) |
| 0.0 | 0.4 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
| 0.0 | 0.2 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.0 | 0.1 | GO:0097319 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.0 | 0.4 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.0 | 0.2 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.0 | 0.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.0 | 0.3 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.0 | 0.1 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.0 | 0.1 | GO:0014057 | positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) |
| 0.0 | 0.1 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.0 | 0.3 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.0 | 0.1 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 0.0 | 0.1 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.0 | 0.1 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) |
| 0.0 | 0.1 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.0 | 0.2 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.0 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 0.0 | 0.1 | GO:0031296 | B cell costimulation(GO:0031296) |
| 0.0 | 0.1 | GO:0039019 | pronephric nephron development(GO:0039019) |
| 0.0 | 0.2 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.0 | 0.5 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.0 | 0.2 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.0 | 0.3 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.2 | GO:1903943 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.0 | 0.1 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 0.0 | 0.0 | GO:0100009 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 0.0 | 0.1 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
| 0.0 | 0.0 | GO:0071283 | regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283) |
| 0.0 | 0.2 | GO:0097240 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.0 | 0.1 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 0.0 | 0.1 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.0 | 0.2 | GO:1901660 | calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034) |
| 0.0 | 0.1 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
| 0.0 | 0.1 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.0 | 0.1 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.0 | 0.2 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 0.0 | 0.0 | GO:0051939 | gamma-aminobutyric acid import(GO:0051939) |
| 0.0 | 0.0 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 0.0 | 1.0 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.0 | GO:0007231 | osmosensory signaling pathway(GO:0007231) |
| 0.0 | 0.1 | GO:0033197 | response to vitamin E(GO:0033197) |
| 0.0 | 0.2 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.0 | 0.2 | GO:0060613 | fat pad development(GO:0060613) |
| 0.0 | 0.1 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.0 | 0.3 | GO:1904261 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.2 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.0 | 0.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.1 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.0 | 0.1 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.0 | 0.2 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.0 | 0.1 | GO:0046504 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.0 | 0.2 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 0.0 | 0.1 | GO:0032328 | alanine transport(GO:0032328) |
| 0.0 | 0.1 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.0 | 0.2 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.3 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.0 | 0.1 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 0.0 | 0.0 | GO:0036482 | neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) |
| 0.0 | 0.1 | GO:0036337 | Fas signaling pathway(GO:0036337) |
| 0.0 | 0.1 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.0 | 0.0 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.0 | 0.0 | GO:1902093 | positive regulation of sperm motility(GO:1902093) |
| 0.0 | 0.1 | GO:1904526 | regulation of microtubule binding(GO:1904526) |
| 0.0 | 0.0 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 0.0 | 0.1 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.0 | 0.1 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.0 | 0.2 | GO:0019934 | cGMP-mediated signaling(GO:0019934) |
| 0.0 | 0.4 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.0 | 0.1 | GO:0021984 | adenohypophysis development(GO:0021984) |
| 0.0 | 0.2 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.0 | 0.2 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.3 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.0 | 0.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.1 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.0 | 0.1 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.0 | 0.1 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.0 | 0.4 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.0 | 0.0 | GO:1904021 | negative regulation of G-protein coupled receptor internalization(GO:1904021) |
| 0.0 | 0.8 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 0.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.0 | 0.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.0 | 0.2 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.0 | 0.2 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.0 | 0.0 | GO:0002023 | reduction of food intake in response to dietary excess(GO:0002023) |
| 0.0 | 0.1 | GO:0033384 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.1 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.0 | 0.0 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.0 | 0.1 | GO:0090625 | mRNA cleavage involved in gene silencing by siRNA(GO:0090625) |
| 0.0 | 0.7 | GO:0030071 | regulation of mitotic metaphase/anaphase transition(GO:0030071) |
| 0.0 | 0.4 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.0 | 0.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.2 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.0 | 0.1 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.0 | 0.1 | GO:2000690 | negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691) |
| 0.0 | 0.0 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.0 | 0.0 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 0.0 | 0.0 | GO:1904717 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
| 0.0 | 0.0 | GO:0070378 | positive regulation of ERK5 cascade(GO:0070378) |
| 0.0 | 0.1 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 0.0 | 0.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0030312 | external encapsulating structure(GO:0030312) |
| 0.1 | 1.2 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 0.5 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.1 | 0.3 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.1 | 0.3 | GO:0034753 | nuclear aryl hydrocarbon receptor complex(GO:0034753) |
| 0.1 | 0.3 | GO:0097362 | MCM8-MCM9 complex(GO:0097362) |
| 0.1 | 0.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 0.2 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.1 | 0.2 | GO:0036025 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.1 | 0.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.0 | 0.4 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.3 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 0.3 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.0 | 0.2 | GO:0039714 | viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517) |
| 0.0 | 0.9 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.2 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.0 | 0.3 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.0 | 0.2 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.0 | 0.2 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.0 | 0.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 0.3 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.0 | 0.1 | GO:0005606 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.0 | 0.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.1 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.0 | 0.1 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 0.0 | 0.5 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.0 | 0.1 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.0 | 0.1 | GO:0071942 | XPC complex(GO:0071942) |
| 0.0 | 0.1 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.0 | 0.1 | GO:0000818 | nuclear MIS12/MIND complex(GO:0000818) |
| 0.0 | 0.1 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 0.0 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.0 | 0.4 | GO:0005883 | neurofilament(GO:0005883) |
| 0.0 | 0.1 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 0.0 | 0.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.1 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 0.1 | GO:0005715 | late recombination nodule(GO:0005715) |
| 0.0 | 0.1 | GO:0033597 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 0.0 | 0.1 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.0 | 0.2 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 0.0 | 0.1 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.0 | 0.2 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.0 | 0.7 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.1 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.0 | 0.2 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.1 | GO:0072589 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.0 | 0.1 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.0 | 0.1 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 2.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.1 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.0 | 0.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.0 | 0.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 0.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.2 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 0.2 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.0 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.0 | 0.1 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.0 | 0.0 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.0 | 0.0 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.0 | 0.1 | GO:0032021 | NELF complex(GO:0032021) |
| 0.0 | 0.4 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.1 | GO:0002139 | stereocilia coupling link(GO:0002139) |
| 0.0 | 0.1 | GO:0031523 | Myb complex(GO:0031523) |
| 0.0 | 0.3 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.1 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.0 | 0.3 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.0 | 0.1 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 0.1 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 0.1 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.1 | GO:0002081 | inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081) |
| 0.0 | 1.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 0.2 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.4 | GO:0043218 | compact myelin(GO:0043218) |
| 0.0 | 0.1 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.0 | GO:0044393 | microspike(GO:0044393) Schwann cell microvillus(GO:0097454) cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.0 | 0.2 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 1.3 | GO:0005901 | caveola(GO:0005901) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.8 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.2 | 1.2 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.2 | 0.8 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.2 | 0.9 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.2 | 0.5 | GO:0045145 | single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145) |
| 0.1 | 1.4 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.1 | 0.4 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.1 | 0.7 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 0.5 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.1 | 0.4 | GO:0097604 | temperature-gated cation channel activity(GO:0097604) |
| 0.1 | 1.1 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.1 | 1.0 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.1 | 0.6 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.1 | 0.3 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.1 | 0.4 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 0.1 | 0.3 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.1 | 0.4 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.1 | 0.2 | GO:0000252 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012) |
| 0.1 | 0.3 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
| 0.1 | 0.3 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.1 | 0.3 | GO:0047708 | biotinidase activity(GO:0047708) |
| 0.1 | 1.1 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.1 | 0.5 | GO:0047756 | chondroitin 4-sulfotransferase activity(GO:0047756) |
| 0.1 | 0.2 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.1 | 0.2 | GO:0003941 | L-serine ammonia-lyase activity(GO:0003941) |
| 0.1 | 0.4 | GO:0004797 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.1 | 0.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.1 | 0.2 | GO:0003865 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 0.1 | 0.2 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.0 | 0.2 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
| 0.0 | 0.2 | GO:0086020 | gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) |
| 0.0 | 0.3 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.0 | 0.3 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.0 | 0.1 | GO:0004577 | N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577) |
| 0.0 | 0.4 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.0 | 0.1 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.0 | 0.1 | GO:0042781 | 3'-tRNA processing endoribonuclease activity(GO:0042781) |
| 0.0 | 0.2 | GO:0016793 | dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567) |
| 0.0 | 0.4 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.0 | 1.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.2 | GO:0016532 | superoxide dismutase copper chaperone activity(GO:0016532) |
| 0.0 | 0.4 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.0 | 0.1 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.0 | 0.3 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.0 | 0.4 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.4 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 0.1 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.0 | 0.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 0.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.1 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.0 | 0.1 | GO:0008969 | phosphohistidine phosphatase activity(GO:0008969) |
| 0.0 | 0.1 | GO:0070336 | flap-structured DNA binding(GO:0070336) |
| 0.0 | 0.2 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.0 | 0.9 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.5 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.0 | 0.5 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.0 | 0.1 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.0 | 0.1 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) |
| 0.0 | 0.4 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.2 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.0 | 0.3 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.0 | 0.7 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.1 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.0 | 0.1 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.0 | 0.1 | GO:0005462 | UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) |
| 0.0 | 0.4 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.0 | 0.3 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.0 | 0.3 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.1 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.0 | 0.1 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 0.0 | 0.1 | GO:0005151 | interleukin-1, Type II receptor binding(GO:0005151) |
| 0.0 | 0.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 0.1 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.0 | 0.2 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.0 | 0.2 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 0.1 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 0.0 | 0.3 | GO:0051378 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.0 | 0.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.0 | 0.1 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 0.0 | 0.3 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 0.5 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.1 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.0 | 0.4 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.0 | 0.2 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.0 | 0.1 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.0 | 0.4 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.0 | 0.1 | GO:0050254 | rhodopsin kinase activity(GO:0050254) |
| 0.0 | 0.1 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 0.0 | 1.0 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.1 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.0 | 0.1 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.0 | 0.1 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.0 | 0.1 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.0 | 0.1 | GO:0000248 | C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704) |
| 0.0 | 0.9 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.1 | GO:0033842 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842) |
| 0.0 | 0.1 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.3 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.0 | 0.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 0.1 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 0.0 | 0.1 | GO:0005330 | dopamine:sodium symporter activity(GO:0005330) |
| 0.0 | 0.1 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.0 | 0.1 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.0 | 0.0 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
| 0.0 | 0.1 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 0.1 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 0.0 | 0.1 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.0 | 0.2 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.1 | GO:0003696 | satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237) |
| 0.0 | 0.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.0 | 0.2 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.0 | 0.0 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.0 | 0.4 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.0 | 0.1 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.0 | 0.2 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 1.2 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.0 | GO:0010857 | calcium-dependent protein kinase activity(GO:0010857) |
| 0.0 | 0.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.1 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.1 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.0 | 0.4 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.1 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.0 | 0.1 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 0.2 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.0 | 0.1 | GO:0051734 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.0 | 0.1 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.1 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.0 | 0.1 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.0 | 0.1 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.0 | 0.0 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 0.0 | 0.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 0.1 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.0 | 0.0 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.0 | 0.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.0 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.0 | 0.5 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.0 | 0.0 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.0 | 0.0 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.0 | 0.0 | GO:0071566 | UFM1 activating enzyme activity(GO:0071566) |
| 0.0 | 0.1 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 0.3 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 0.2 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.0 | 0.1 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.0 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.1 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 0.3 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.4 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.9 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.4 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.1 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 0.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.2 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.4 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 0.5 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.3 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 2.1 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 0.7 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 0.8 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.7 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.4 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.6 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.4 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.4 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.0 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.3 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 0.4 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.3 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.2 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.0 | 0.4 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.3 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.0 | 0.4 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 0.3 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.4 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 0.4 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.2 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.2 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 0.4 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.5 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.1 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 0.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.3 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |