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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for DLX4_HOXD8

Z-value: 0.95

Motif logo

Transcription factors associated with DLX4_HOXD8

Gene Symbol Gene ID Gene Info
ENSG00000108813.11 distal-less homeobox 4
ENSG00000175879.9 homeobox D8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD8hg38_v1_chr2_+_176129680_176129764-0.791.9e-02Click!
DLX4hg38_v1_chr17_+_49969178_49969214-0.724.2e-02Click!

Activity profile of DLX4_HOXD8 motif

Sorted Z-values of DLX4_HOXD8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91179355 3.05 ENST00000550563.5
ENST00000546370.5
decorin
chr12_-_91179472 2.44 ENST00000550099.5
ENST00000546391.5
decorin
chr13_+_101489940 2.05 ENST00000376162.7
integrin subunit beta like 1
chr1_-_72100930 1.65 ENST00000306821.3
neuronal growth regulator 1
chr12_-_91153149 1.48 ENST00000550758.1
decorin
chr5_-_20575850 1.38 ENST00000507958.5
cadherin 18
chr2_-_224947030 1.23 ENST00000409592.7
dedicator of cytokinesis 10
chr8_-_13276491 1.20 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr10_-_77638369 0.97 ENST00000372443.6
potassium calcium-activated channel subfamily M alpha 1
chr9_+_87497222 0.93 ENST00000358077.9
death associated protein kinase 1
chr12_-_91178520 0.89 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
decorin
chr10_-_77637721 0.84 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr12_+_18242955 0.83 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr10_-_77637789 0.83 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr1_-_145910031 0.83 ENST00000369304.8
integrin subunit alpha 10
chr9_+_87497852 0.82 ENST00000408954.8
death associated protein kinase 1
chr1_+_163069353 0.82 ENST00000531057.5
ENST00000527809.5
ENST00000367908.8
ENST00000367909.11
regulator of G protein signaling 4
chr1_-_145910066 0.81 ENST00000539363.2
integrin subunit alpha 10
chr10_-_77637902 0.80 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr11_-_63608542 0.79 ENST00000540943.1
phospholipase A and acyltransferase 3
chr9_+_96928310 0.75 ENST00000354649.7
NUT family member 2G
chr14_-_106005574 0.73 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr3_+_157436842 0.73 ENST00000295927.4
pentraxin 3
chr3_-_100993507 0.73 ENST00000284322.10
ABI family member 3 binding protein
chr6_-_87095059 0.71 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr4_-_155866277 0.64 ENST00000537611.3
acid sensing ion channel subunit family member 5
chr5_+_157269317 0.63 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr19_+_49513353 0.60 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr8_+_96584920 0.60 ENST00000521590.5
syndecan 2
chr22_+_38957522 0.57 ENST00000618553.1
ENST00000249116.7
apolipoprotein B mRNA editing enzyme catalytic subunit 3A
chr8_+_38728186 0.53 ENST00000519416.5
ENST00000520615.5
transforming acidic coiled-coil containing protein 1
chr2_+_108607140 0.52 ENST00000410093.5
LIM zinc finger domain containing 1
chr8_+_76681208 0.52 ENST00000651372.2
zinc finger homeobox 4
chr5_+_93583212 0.50 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr12_+_59664677 0.49 ENST00000548610.5
solute carrier family 16 member 7
chrX_+_10158448 0.49 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr22_-_28306645 0.49 ENST00000612946.4
tetratricopeptide repeat domain 28
chr9_-_21482313 0.48 ENST00000448696.4
interferon epsilon
chr1_-_91906280 0.47 ENST00000370399.6
transforming growth factor beta receptor 3
chr8_-_38468627 0.46 ENST00000683815.1
ENST00000684654.1
ENST00000447712.7
ENST00000397091.9
fibroblast growth factor receptor 1
chr2_+_200585987 0.45 ENST00000374700.7
aldehyde oxidase 1
chr6_-_117425855 0.44 ENST00000368508.7
ROS proto-oncogene 1, receptor tyrosine kinase
chr17_-_78874038 0.44 ENST00000586057.5
TIMP metallopeptidase inhibitor 2
chr4_+_70050431 0.44 ENST00000511674.5
ENST00000246896.8
histatin 1
chr12_+_51424965 0.43 ENST00000514353.7
solute carrier family 4 member 8
chr10_-_77140757 0.43 ENST00000637862.2
potassium calcium-activated channel subfamily M alpha 1
chr5_-_147906530 0.42 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr11_-_124800630 0.42 ENST00000239614.8
ENST00000674284.1
Myb/SANT DNA binding domain containing 2
chr5_+_172641241 0.41 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr6_+_108656346 0.40 ENST00000540898.1
forkhead box O3
chr12_-_46825949 0.40 ENST00000547477.5
ENST00000447411.5
ENST00000266579.9
solute carrier family 38 member 4
chr15_-_55365231 0.39 ENST00000568543.1
cell cycle progression 1
chr2_-_157444044 0.39 ENST00000264192.8
cytohesin 1 interacting protein
chr6_+_151325665 0.38 ENST00000354675.10
A-kinase anchoring protein 12
chr2_+_151357583 0.38 ENST00000243347.5
TNF alpha induced protein 6
chr6_-_52994248 0.37 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chrX_+_86714623 0.37 ENST00000484479.1
dachshund family transcription factor 2
chr12_-_91179517 0.37 ENST00000551354.1
decorin
chr2_+_108621260 0.37 ENST00000409441.5
LIM zinc finger domain containing 1
chr14_-_52069228 0.36 ENST00000617139.4
nidogen 2
chr14_-_52069039 0.36 ENST00000216286.10
nidogen 2
chr20_+_45416551 0.35 ENST00000639292.1
phosphatidylinositol glycan anchor biosynthesis class T
chr5_-_97183203 0.35 ENST00000508447.1
ENST00000283109.8
RIO kinase 2
chr9_+_87497675 0.35 ENST00000472284.5
ENST00000469640.6
death associated protein kinase 1
chr12_-_10826358 0.35 ENST00000240619.2
taste 2 receptor member 10
chr21_-_30372265 0.34 ENST00000399889.4
keratin associated protein 13-2
chr7_+_138460238 0.34 ENST00000343526.9
tripartite motif containing 24
chr1_+_158461574 0.34 ENST00000641432.1
ENST00000641460.1
ENST00000641535.1
ENST00000641971.1
olfactory receptor family 10 subfamily K member 1
chr9_+_117704168 0.34 ENST00000472304.2
ENST00000394487.5
toll like receptor 4
chr7_-_93148345 0.33 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr6_-_57221402 0.33 ENST00000317483.4
RAB23, member RAS oncogene family
chr13_+_43023577 0.32 ENST00000379221.4
DnaJ heat shock protein family (Hsp40) member C15
chr11_-_27700447 0.32 ENST00000356660.9
brain derived neurotrophic factor
chr1_+_159780930 0.32 ENST00000368109.5
ENST00000368108.7
ENST00000368107.2
dual specificity phosphatase 23
chr3_+_155083889 0.32 ENST00000680282.1
membrane metalloendopeptidase
chr14_+_75632610 0.32 ENST00000555027.1
FLVCR heme transporter 2
chr20_+_36214373 0.31 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chr2_+_108377947 0.31 ENST00000272452.7
sulfotransferase family 1C member 4
chr20_+_13008919 0.31 ENST00000399002.7
ENST00000434210.5
serine palmitoyltransferase long chain base subunit 3
chr2_-_201698040 0.31 ENST00000396886.7
ENST00000409143.5
membrane palmitoylated protein 4
chr5_-_88823763 0.31 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr5_+_42756811 0.30 ENST00000388827.4
ENST00000361970.10
coiled-coil domain containing 152
chr11_-_33717409 0.30 ENST00000651485.1
CD59 molecule (CD59 blood group)
chr2_-_178478499 0.30 ENST00000434643.6
FKBP prolyl isomerase 7
chr1_+_115029823 0.30 ENST00000256592.3
thyroid stimulating hormone subunit beta
chr2_+_157257687 0.29 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr6_-_15586006 0.29 ENST00000462989.6
dystrobrevin binding protein 1
chr5_+_141150012 0.29 ENST00000231136.4
ENST00000622991.1
protocadherin beta 6
chr10_-_13300051 0.29 ENST00000479604.1
ENST00000263038.9
phytanoyl-CoA 2-hydroxylase
chr1_-_183653307 0.29 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr10_+_122560679 0.29 ENST00000657942.1
deleted in malignant brain tumors 1
chr10_+_122560751 0.28 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr21_-_26843063 0.28 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr8_+_103372388 0.28 ENST00000520337.1
collagen triple helix repeat containing 1
chrX_-_77634229 0.28 ENST00000675732.1
ATRX chromatin remodeler
chr2_+_10368645 0.28 ENST00000613496.4
hippocalcin like 1
chr14_-_106470788 0.27 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr21_-_30497160 0.27 ENST00000334058.3
keratin associated protein 19-4
chr9_+_117704382 0.27 ENST00000646089.1
ENST00000355622.8
novel protein
toll like receptor 4
chr1_-_197146620 0.27 ENST00000367409.9
ENST00000680265.1
assembly factor for spindle microtubules
chr9_-_92482350 0.27 ENST00000375543.2
asporin
chr14_-_89619118 0.26 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
forkhead box N3
chr17_-_445939 0.26 ENST00000329099.4
refilin B
chr11_+_56027654 0.26 ENST00000641320.1
olfactory receptor family 5 subfamily AS member 1
chr12_-_8227587 0.26 ENST00000442295.2
ENST00000307435.10
ENST00000538603.6
family with sequence similarity 90 member A1
chrX_-_102516714 0.26 ENST00000289373.5
thymosin beta 15A
chr2_-_201698692 0.26 ENST00000315506.11
ENST00000359962.9
ENST00000620095.4
membrane palmitoylated protein 4
chr2_+_200305976 0.25 ENST00000358677.9
spermatogenesis associated serine rich 2 like
chr1_+_240014319 0.25 ENST00000447095.5
formin 2
chr1_-_168729187 0.25 ENST00000367817.4
dermatopontin
chr12_+_53441724 0.25 ENST00000551003.5
ENST00000429243.7
ENST00000549068.5
ENST00000549740.5
ENST00000546581.5
ENST00000549581.5
ENST00000547368.5
ENST00000379786.8
ENST00000551945.5
ENST00000547717.1
proline rich 13
novel transcript
chr11_-_27700472 0.25 ENST00000418212.5
ENST00000533246.5
brain derived neurotrophic factor
chr2_-_189179754 0.25 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr19_-_21852006 0.25 ENST00000594012.5
ENST00000595461.5
ENST00000357491.10
ENST00000596899.1
zinc finger protein 43
chr1_-_113871665 0.24 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr4_+_122826679 0.24 ENST00000264498.8
fibroblast growth factor 2
chr14_-_91732059 0.24 ENST00000553329.5
ENST00000256343.8
cation channel sperm associated auxiliary subunit beta
chr4_-_39032343 0.24 ENST00000381938.4
transmembrane protein 156
chr2_-_213151590 0.24 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr19_-_45424364 0.24 ENST00000589165.5
ERCC excision repair 1, endonuclease non-catalytic subunit
chr4_-_117085541 0.24 ENST00000310754.5
translocation associated membrane protein 1 like 1
chr15_+_41621134 0.24 ENST00000566718.6
MAX dimerization protein MGA
chr12_-_76486061 0.23 ENST00000548341.5
oxysterol binding protein like 8
chr19_-_21851968 0.23 ENST00000598381.5
zinc finger protein 43
chr6_+_72216442 0.23 ENST00000425662.6
ENST00000453976.6
regulating synaptic membrane exocytosis 1
chr13_-_109786567 0.23 ENST00000375856.5
insulin receptor substrate 2
chr17_-_69268812 0.23 ENST00000586811.1
ATP binding cassette subfamily A member 5
chr2_-_181680490 0.23 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
ceramide kinase like
neuronal differentiation 1
chrX_-_155264471 0.23 ENST00000369454.4
RAB39B, member RAS oncogene family
chr19_+_1266653 0.22 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chr3_-_132684685 0.22 ENST00000512094.5
ENST00000632629.1
nephrocystin 3
NPHP3-ACAD11 readthrough (NMD candidate)
chr3_+_141384790 0.22 ENST00000507722.5
zinc finger and BTB domain containing 38
chr3_+_69866217 0.22 ENST00000314589.10
melanocyte inducing transcription factor
chr4_-_73988179 0.22 ENST00000296028.4
pro-platelet basic protein
chr8_-_13514744 0.22 ENST00000316609.9
DLC1 Rho GTPase activating protein
chr3_-_52679713 0.22 ENST00000296302.11
ENST00000356770.8
ENST00000337303.8
ENST00000409057.5
ENST00000410007.5
ENST00000409114.7
ENST00000409767.5
ENST00000423351.5
polybromo 1
chr1_+_103617427 0.21 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr15_-_56465130 0.21 ENST00000260453.4
meiosis specific nuclear structural 1
chr1_+_108560031 0.21 ENST00000405454.1
ENST00000370035.8
family with sequence similarity 102 member B
chr16_+_32995048 0.21 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr3_+_45886501 0.21 ENST00000395963.2
C-C motif chemokine receptor 9
chr11_+_5689780 0.21 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chr13_+_75804221 0.21 ENST00000489941.6
ENST00000525373.5
LIM domain 7
chr11_-_122116215 0.21 ENST00000560104.2
BH3-like motif containing, cell death inducer
chr5_+_108747879 0.20 ENST00000281092.9
FER tyrosine kinase
chr12_+_75481204 0.20 ENST00000550491.1
GLI pathogenesis related 1
chr9_+_4490388 0.20 ENST00000262352.8
solute carrier family 1 member 1
chr12_-_10453330 0.20 ENST00000347831.9
ENST00000359151.8
killer cell lectin like receptor C1
chr12_+_18262730 0.20 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr9_-_110999458 0.20 ENST00000374430.6
lysophosphatidic acid receptor 1
chr3_+_155083523 0.20 ENST00000680057.1
membrane metalloendopeptidase
chr15_+_41621492 0.20 ENST00000570161.6
MAX dimerization protein MGA
chr1_-_145403303 0.20 ENST00000622803.4
ENST00000594479.7
NBPF member 20
chr19_+_21397156 0.20 ENST00000339914.6
ENST00000599461.1
zinc finger protein 493
chr3_+_69936583 0.20 ENST00000314557.10
ENST00000394351.9
melanocyte inducing transcription factor
chr1_-_48472166 0.20 ENST00000371847.8
ENST00000396199.7
spermatogenesis associated 6
chr13_-_60013178 0.20 ENST00000498416.2
ENST00000465066.5
diaphanous related formin 3
chr5_-_126595237 0.20 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr16_-_15381047 0.20 ENST00000534094.1
nuclear pore complex interacting protein family member A5
chr4_-_65670478 0.20 ENST00000613740.5
ENST00000622150.4
ENST00000511294.1
EPH receptor A5
chr2_+_131527833 0.20 ENST00000295171.10
ENST00000467992.6
ENST00000409856.8
coiled-coil domain containing 74A
chr2_-_127220293 0.20 ENST00000664447.2
ENST00000409327.2
cytochrome P450 family 27 subfamily C member 1
chr12_-_119803383 0.20 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr19_-_58353482 0.20 ENST00000263100.8
alpha-1-B glycoprotein
chr17_-_55732074 0.20 ENST00000575734.5
transmembrane protein 100
chr5_+_141382702 0.19 ENST00000617050.1
ENST00000518325.2
protocadherin gamma subfamily A, 7
chr1_-_60073750 0.19 ENST00000371201.3
chromosome 1 open reading frame 87
chr6_+_135851681 0.19 ENST00000308191.11
phosphodiesterase 7B
chr1_+_103571077 0.19 ENST00000610648.1
amylase alpha 2B
chr11_+_20022550 0.19 ENST00000533917.5
neuron navigator 2
chr12_-_96400365 0.19 ENST00000261211.8
ENST00000543119.6
cyclin dependent kinase 17
chr14_-_80959484 0.19 ENST00000555529.5
ENST00000556042.5
ENST00000556981.5
centrosomal protein 128
chr12_+_54854505 0.19 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr3_+_155080307 0.19 ENST00000360490.7
membrane metalloendopeptidase
chr1_-_186375671 0.19 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr9_+_18474206 0.19 ENST00000276935.6
ADAMTS like 1
chr1_+_248509536 0.19 ENST00000641501.1
olfactory receptor family 2 subfamily G member 6
chr1_-_79006773 0.19 ENST00000671209.1
adhesion G protein-coupled receptor L4
chr2_+_200306648 0.19 ENST00000409140.8
spermatogenesis associated serine rich 2 like
chr8_+_17027230 0.19 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr20_+_58907981 0.19 ENST00000656419.1
GNAS complex locus
chr19_+_14583076 0.19 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chr1_-_205121964 0.19 ENST00000264515.11
RB binding protein 5, histone lysine methyltransferase complex subunit
chr16_+_53099100 0.19 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr11_-_55936400 0.19 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr12_-_10849464 0.19 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
proline rich 4
chr5_+_55160161 0.18 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr5_-_160400025 0.18 ENST00000523213.1
ENST00000408953.4
zinc finger BED-type containing 8
chr8_-_107497909 0.18 ENST00000517746.6
angiopoietin 1
chr6_-_31680377 0.18 ENST00000383237.4
lymphocyte antigen 6 family member G5C
chr12_-_62935117 0.18 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr14_+_74019341 0.18 ENST00000394009.5
ENST00000464394.5
basal body orientation factor 1
chr2_+_161136901 0.18 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr7_+_20647388 0.18 ENST00000258738.10
ATP binding cassette subfamily B member 5
chr6_+_72366730 0.18 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr10_-_122845850 0.18 ENST00000392790.6
CUB and zona pellucida like domains 1
chrX_-_93673558 0.18 ENST00000475430.2
ENST00000373079.4
nucleosome assembly protein 1 like 3
chr1_+_248508073 0.18 ENST00000641804.1
olfactory receptor family 2 subfamily G member 6
chr1_+_210328244 0.18 ENST00000541565.5
ENST00000413764.6
hedgehog acyltransferase
chr2_+_108378176 0.18 ENST00000409309.3
sulfotransferase family 1C member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX4_HOXD8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 3.9 GO:0034465 response to carbon monoxide(GO:0034465)
0.2 0.7 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.2 0.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.6 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 0.6 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 0.6 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.2 0.5 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.5 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.4 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.6 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.3 GO:1904907 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.1 0.3 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 0.3 GO:0050904 diapedesis(GO:0050904)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 1.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.4 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 0.6 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 2.0 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.2 GO:0031445 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.1 0.2 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.4 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.3 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.1 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0072573 tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.2 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.2 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.0 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 1.1 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.0 GO:1901355 response to rapamycin(GO:1901355)
0.0 1.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0044407 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0090131 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.0 0.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.0 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.5 GO:0030728 ovulation(GO:0030728)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 1.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.0 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.0 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.0 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.0 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.0 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.0 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.0 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.5 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.0 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368) protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.0 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.0 GO:0010958 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.6 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 5.3 GO:0005901 caveola(GO:0005901)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 1.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0030478 actin cap(GO:0030478)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 0.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 1.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 0.6 GO:0035375 zymogen binding(GO:0035375)
0.2 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.6 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 7.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.5 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0032560 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.0 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.0 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.4 PID SHP2 PATHWAY SHP2 signaling
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.0 ST ADRENERGIC Adrenergic Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events