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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for DUXA

Z-value: 1.09

Motif logo

Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
ENSG00000258873.3 double homeobox A

Activity profile of DUXA motif

Sorted Z-values of DUXA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91153149 4.39 ENST00000550758.1
decorin
chr9_-_92424427 1.70 ENST00000375550.5
osteomodulin
chr5_-_111976925 1.48 ENST00000395634.7
neuronal regeneration related protein
chr13_+_101489940 1.39 ENST00000376162.7
integrin subunit beta like 1
chr10_+_68106109 1.23 ENST00000540630.5
ENST00000354393.6
myopalladin
chr5_-_151157722 1.19 ENST00000517486.5
ENST00000377751.9
ENST00000521512.5
ENST00000517757.5
ENST00000354546.10
annexin A6
chr1_+_78490966 1.17 ENST00000370757.8
ENST00000370756.3
prostaglandin F receptor
chr1_+_78303865 0.93 ENST00000370758.5
prostaglandin F receptor
chr1_+_12857086 0.92 ENST00000240189.2
PRAME family member 2
chr2_-_224947030 0.90 ENST00000409592.7
dedicator of cytokinesis 10
chr1_+_13068677 0.81 ENST00000614839.4
PRAME family member 25
chr1_-_91886144 0.80 ENST00000212355.9
transforming growth factor beta receptor 3
chr5_-_151141631 0.75 ENST00000523714.5
ENST00000521749.5
annexin A6
chr5_-_76623391 0.72 ENST00000296641.5
ENST00000504899.1
coagulation factor II thrombin receptor like 2
chr1_-_91906280 0.71 ENST00000370399.6
transforming growth factor beta receptor 3
chr10_-_48652493 0.67 ENST00000435790.6
Rho GTPase activating protein 22
chr3_+_45886501 0.66 ENST00000395963.2
C-C motif chemokine receptor 9
chr2_-_201698692 0.66 ENST00000315506.11
ENST00000359962.9
ENST00000620095.4
membrane palmitoylated protein 4
chr2_-_201698628 0.65 ENST00000602867.1
ENST00000409474.8
membrane palmitoylated protein 4
chr16_+_21704963 0.64 ENST00000388957.3
otoancorin
chr1_+_12791397 0.63 ENST00000332296.7
PRAME family member 1
chr14_+_22147988 0.59 ENST00000390457.2
T cell receptor alpha variable 27
chr1_+_13070853 0.55 ENST00000619661.2
PRAME family member 25
chr8_+_69466617 0.53 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
sulfatase 1
chr3_+_69763726 0.53 ENST00000448226.9
melanocyte inducing transcription factor
chr10_-_13972355 0.52 ENST00000264546.10
FERM domain containing 4A
chr1_+_77918128 0.52 ENST00000342754.5
nexilin F-actin binding protein
chr19_-_3061403 0.47 ENST00000586839.1
TLE family member 5, transcriptional modulator
chr3_-_15797930 0.45 ENST00000683139.1
ankyrin repeat domain 28
chr11_-_96343170 0.45 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr4_-_141212877 0.44 ENST00000420921.6
ring finger protein 150
chr3_+_141402322 0.44 ENST00000510338.5
ENST00000504673.5
zinc finger and BTB domain containing 38
chr2_+_108607140 0.43 ENST00000410093.5
LIM zinc finger domain containing 1
chr5_+_98773651 0.43 ENST00000513185.3
repulsive guidance molecule BMP co-receptor b
chr16_-_29995601 0.42 ENST00000279392.8
ENST00000564026.1
HIRA interacting protein 3
chr3_-_165196689 0.40 ENST00000241274.3
SLIT and NTRK like family member 3
chr12_-_89656051 0.39 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr2_-_40453438 0.38 ENST00000455476.5
solute carrier family 8 member A1
chr2_-_223602284 0.38 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr7_+_7968787 0.36 ENST00000223145.10
glucocorticoid induced 1
chr13_+_32031706 0.36 ENST00000542859.6
FRY microtubule binding protein
chr12_-_76423256 0.36 ENST00000546946.5
oxysterol binding protein like 8
chr12_-_89656093 0.35 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr5_+_141355003 0.35 ENST00000571252.3
ENST00000612927.1
protocadherin gamma subfamily A, 4
chr5_+_173144442 0.34 ENST00000231668.13
ENST00000351486.10
ENST00000352523.10
ENST00000393770.4
BCL2 interacting protein 1
chr5_-_88731827 0.34 ENST00000627170.2
myocyte enhancer factor 2C
chr7_+_121062765 0.33 ENST00000423795.5
cadherin like and PC-esterase domain containing 1
chr12_+_54854505 0.33 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr1_+_13171848 0.32 ENST00000415919.3
PRAME family member 9
chr12_+_26011713 0.32 ENST00000542004.5
Ras association domain family member 8
chr12_+_18262730 0.31 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr1_-_165445220 0.30 ENST00000619224.1
retinoid X receptor gamma
chr1_-_12886201 0.30 ENST00000235349.6
PRAME family member 4
chrX_+_54808359 0.29 ENST00000375058.5
ENST00000375060.5
MAGE family member D2
chr1_-_12898270 0.28 ENST00000235347.4
PRAME family member 10
chr1_-_165445088 0.28 ENST00000359842.10
retinoid X receptor gamma
chrX_+_54808334 0.28 ENST00000218439.8
MAGE family member D2
chr3_-_71360753 0.27 ENST00000648783.1
forkhead box P1
chrX_+_54809060 0.27 ENST00000396224.1
MAGE family member D2
chrX_+_86714623 0.27 ENST00000484479.1
dachshund family transcription factor 2
chr1_-_12945416 0.27 ENST00000415464.6
PRAME family member 6
chr5_+_141192330 0.27 ENST00000239446.6
protocadherin beta 10
chr1_-_12831410 0.27 ENST00000619922.1
PRAME family member 11
chr17_+_68515399 0.26 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr3_+_108602776 0.26 ENST00000497905.5
ENST00000463306.1
DAZ interacting zinc finger protein 3
chr1_-_13116854 0.26 ENST00000621994.3
heterogeneous nuclear ribonucleoprotein C like 2
chr6_+_52420107 0.26 ENST00000636489.1
ENST00000637089.1
ENST00000637353.1
ENST00000637263.1
EF-hand domain containing 1
chr6_+_28124596 0.25 ENST00000340487.5
zinc finger and SCAN domain containing 16
chr2_-_218010202 0.25 ENST00000646520.1
tensin 1
chr7_-_138002017 0.25 ENST00000452463.5
ENST00000456390.5
ENST00000330387.11
cAMP responsive element binding protein 3 like 2
chr1_+_13254212 0.25 ENST00000622421.2
PRAME family member 5
chr19_+_52297157 0.24 ENST00000595962.6
ENST00000598016.5
ENST00000334564.11
ENST00000490272.1
zinc finger protein 480
chr2_+_201129318 0.24 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr5_+_141392616 0.24 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr16_+_77722502 0.24 ENST00000564085.5
ENST00000268533.9
ENST00000568787.5
ENST00000437314.3
ENST00000563839.1
nudix hydrolase 7
chr2_+_227813834 0.24 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr5_+_154858537 0.23 ENST00000517568.5
ENST00000524105.5
CCR4-NOT transcription complex subunit 8
chr19_-_6393205 0.23 ENST00000595047.5
general transcription factor IIF subunit 1
chr5_+_119629552 0.23 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chr1_+_13315581 0.23 ENST00000376152.2
PRAME family member 15
chr16_+_77722473 0.23 ENST00000613075.4
nudix hydrolase 7
chr1_+_13303539 0.22 ENST00000437300.2
PRAME family member 33
chr17_-_7241787 0.22 ENST00000577035.5
GABA type A receptor-associated protein
chr3_-_15798184 0.22 ENST00000624145.3
ankyrin repeat domain 28
chr15_+_44427793 0.22 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTD small phosphatase like 2
chr4_-_75724362 0.22 ENST00000677583.1
G3BP stress granule assembly factor 2
chr1_+_170532131 0.22 ENST00000367762.2
ENST00000367763.8
golgin, RAB6 interacting
chr14_+_34993240 0.22 ENST00000677647.1
signal recognition particle 54
chr12_+_25973748 0.21 ENST00000542865.5
Ras association domain family member 8
chr6_-_15548360 0.21 ENST00000509674.1
dystrobrevin binding protein 1
chr4_-_75724386 0.21 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP stress granule assembly factor 2
chr1_-_27672178 0.20 ENST00000339145.8
ENST00000361157.11
ENST00000362020.4
ENST00000679644.1
interferon alpha inducible protein 6
chr7_+_134646845 0.20 ENST00000344924.8
bisphosphoglycerate mutase
chr7_-_138663152 0.20 ENST00000288513.9
SVOP like
chr12_-_109996216 0.20 ENST00000551209.5
ENST00000550186.5
GIT ArfGAP 2
chr2_-_197198034 0.20 ENST00000328737.6
ankyrin repeat domain 44
chr1_-_12947580 0.20 ENST00000376189.5
PRAME family member 6
chr5_+_154858218 0.20 ENST00000523698.5
ENST00000517876.5
ENST00000520472.5
CCR4-NOT transcription complex subunit 8
chr5_+_141343818 0.19 ENST00000619750.1
ENST00000253812.8
protocadherin gamma subfamily A, 3
chr5_+_154858482 0.19 ENST00000519211.5
ENST00000522458.5
ENST00000519903.5
ENST00000521450.5
ENST00000403027.6
CCR4-NOT transcription complex subunit 8
chr15_+_41286011 0.19 ENST00000661438.1
novel protein
chr5_+_154858594 0.19 ENST00000519430.5
ENST00000520671.5
ENST00000521583.5
ENST00000285896.11
ENST00000518028.5
ENST00000519404.5
ENST00000519394.5
ENST00000518775.5
CCR4-NOT transcription complex subunit 8
chr3_-_196270540 0.18 ENST00000419333.5
phosphate cytidylyltransferase 1, choline, alpha
chr2_-_55334529 0.18 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chr12_-_49187369 0.18 ENST00000547939.6
tubulin alpha 1a
chr7_+_134646798 0.18 ENST00000418040.5
ENST00000393132.2
bisphosphoglycerate mutase
chr7_-_138001794 0.18 ENST00000616381.4
ENST00000620715.4
cAMP responsive element binding protein 3 like 2
chr20_-_45670239 0.18 ENST00000324384.4
ENST00000356562.6
WAP four-disulfide core domain 11
chr2_+_161136901 0.17 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr16_+_29995661 0.17 ENST00000304516.11
INO80 complex subunit E
chr6_+_167291329 0.17 ENST00000366829.2
unc-93 homolog A
chr6_+_167291309 0.17 ENST00000230256.8
unc-93 homolog A
chr7_-_137343752 0.16 ENST00000393083.2
pleiotrophin
chr1_+_53014926 0.16 ENST00000430330.6
ENST00000408941.7
ENST00000478274.6
ENST00000484100.5
ENST00000435345.6
ENST00000488965.1
sterol carrier protein 2
chr8_-_115492221 0.16 ENST00000518018.1
transcriptional repressor GATA binding 1
chr10_+_80537902 0.16 ENST00000339284.6
ENST00000646907.2
SH2 domain containing 4B
chr9_+_136982993 0.16 ENST00000408973.3
lipocalin like 1
chr6_-_169253835 0.16 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr4_+_70195719 0.16 ENST00000683306.1
odontogenic, ameloblast associated
chr6_+_31158518 0.15 ENST00000376255.4
ENST00000376257.8
transcription factor 19
chr12_+_8509460 0.15 ENST00000382064.6
C-type lectin domain family 4 member D
chr17_-_41397600 0.15 ENST00000251645.3
keratin 31
chr2_+_201129483 0.15 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr17_-_37542361 0.15 ENST00000614196.1
synergin gamma
chr1_+_95151377 0.15 ENST00000604203.1
TLCD4-RWDD3 readthrough
chr19_-_12722547 0.15 ENST00000592287.5
transportin 2
chr12_-_54259531 0.14 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr7_-_137343688 0.14 ENST00000348225.7
pleiotrophin
chr21_+_46635595 0.14 ENST00000451211.6
ENST00000458387.6
ENST00000397638.6
ENST00000291705.11
ENST00000397637.5
ENST00000334494.8
ENST00000397628.5
ENST00000355680.8
ENST00000440086.5
protein arginine methyltransferase 2
chr17_+_68525795 0.14 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr2_+_54115437 0.14 ENST00000303536.8
ENST00000394666.7
acylphosphatase 2
chr20_-_35411963 0.14 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
ubiquinol-cytochrome c reductase complex assembly factor 1
chr12_-_10454485 0.14 ENST00000408006.7
ENST00000544822.2
ENST00000536188.5
killer cell lectin like receptor C1
chr14_-_80231052 0.14 ENST00000557010.5
iodothyronine deiodinase 2
chr17_-_81891562 0.14 ENST00000505490.3
Aly/REF export factor
chr4_+_147732070 0.14 ENST00000336498.8
Rho GTPase activating protein 10
chr15_+_70936487 0.14 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chr4_+_107989880 0.14 ENST00000309522.8
ENST00000403312.6
ENST00000638559.1
ENST00000682373.1
hydroxyacyl-CoA dehydrogenase
chr6_+_72366730 0.13 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr19_-_17377334 0.13 ENST00000252590.9
ENST00000599426.1
plasmalemma vesicle associated protein
chr2_+_54115396 0.13 ENST00000406041.5
acylphosphatase 2
chr3_+_160225409 0.13 ENST00000326474.5
chromosome 3 open reading frame 80
chr9_+_136848724 0.13 ENST00000371661.5
phosphohistidine phosphatase 1
chr16_+_29996201 0.13 ENST00000620599.4
ENST00000563197.6
ENST00000567254.5
ENST00000567705.5
INO80 complex subunit E
chr1_-_173824856 0.13 ENST00000682279.1
centromere protein L
chr17_-_7242156 0.13 ENST00000571129.5
ENST00000571253.1
ENST00000573928.1
ENST00000302386.10
GABA type A receptor-associated protein
chr6_-_169250825 0.13 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr5_+_69565122 0.13 ENST00000507595.1
GTF2H2 family member C
chr3_+_186635967 0.12 ENST00000431018.5
ENST00000450521.5
fetuin B
chr7_+_124476371 0.12 ENST00000473520.1
SSU72 pseudogene 8
chr16_+_69187125 0.12 ENST00000336278.8
syntrophin beta 2
chr8_+_23288081 0.12 ENST00000265806.12
ENST00000519952.6
ENST00000518840.6
R3H domain and coiled-coil containing 1
chr3_-_177196451 0.12 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1X receptor 1
chr5_+_55024250 0.12 ENST00000231009.3
granzyme K
chrX_+_101623121 0.12 ENST00000491568.6
ENST00000479298.5
ENST00000471229.7
armadillo repeat containing X-linked 3
chr12_-_119877270 0.12 ENST00000261833.11
ENST00000612548.4
citron rho-interacting serine/threonine kinase
chr5_+_150497772 0.12 ENST00000523767.5
N-deacetylase and N-sulfotransferase 1
chr17_+_44957907 0.12 ENST00000678938.1
N-myristoyltransferase 1
chr9_+_136849401 0.12 ENST00000247665.12
phosphohistidine phosphatase 1
chr9_-_6015607 0.11 ENST00000485372.1
ENST00000259569.6
ENST00000623170.1
RAN binding protein 6
chr16_-_89719369 0.11 ENST00000561976.5
VPS9 domain containing 1
chr3_-_196515315 0.11 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr12_+_71938837 0.11 ENST00000333850.4
tryptophan hydroxylase 2
chr1_+_13060769 0.11 ENST00000617807.3
heterogeneous nuclear ribonucleoprotein C like 3
chr12_-_119877300 0.11 ENST00000392521.7
citron rho-interacting serine/threonine kinase
chr13_+_19633642 0.11 ENST00000361479.10
M-phase phosphoprotein 8
chrX_+_77910656 0.11 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr6_+_116369837 0.11 ENST00000645988.1
dermatan sulfate epimerase
chr7_+_135148041 0.11 ENST00000275767.3
transmembrane protein 140
chr11_+_67483019 0.11 ENST00000279146.8
ENST00000528641.7
ENST00000682324.1
ENST00000684006.1
ENST00000683237.1
ENST00000684657.1
aryl hydrocarbon receptor interacting protein
chr4_-_8428424 0.11 ENST00000514423.1
ENST00000503233.5
acyl-CoA oxidase 3, pristanoyl
chr2_+_201129826 0.11 ENST00000457277.5
CASP8 and FADD like apoptosis regulator
chr15_-_65115185 0.11 ENST00000559089.6
ubiquitin associated protein 1 like
chr11_+_43311963 0.11 ENST00000534695.5
ENST00000455725.6
ENST00000531273.6
ENST00000420461.6
ENST00000378852.7
ENST00000534600.5
apoptosis inhibitor 5
chr16_-_57186014 0.10 ENST00000566584.5
ENST00000566481.5
ENST00000566077.5
ENST00000564108.5
ENST00000309137.13
ENST00000565458.5
ENST00000566681.1
ENST00000567439.5
proteasome activator subunit 3 interacting protein 1
chr6_+_36029082 0.10 ENST00000472333.1
mitogen-activated protein kinase 14
chr8_-_61689768 0.10 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
aspartate beta-hydroxylase
chr1_-_157841800 0.10 ENST00000368174.5
CD5 molecule like
chr12_-_57237090 0.10 ENST00000556732.1
NDUFA4 mitochondrial complex associated like 2
chr18_+_3449413 0.10 ENST00000549253.5
TGFB induced factor homeobox 1
chr8_+_24294107 0.10 ENST00000437154.6
ADAM metallopeptidase domain 28
chr4_+_653171 0.10 ENST00000488061.5
ENST00000429163.6
phosphodiesterase 6B
chr9_+_72577369 0.10 ENST00000651183.1
transmembrane channel like 1
chr4_-_68349981 0.10 ENST00000510746.1
ENST00000355665.7
ENST00000344157.9
YTH domain containing 1
chr19_+_21142024 0.09 ENST00000600692.5
ENST00000599296.5
ENST00000594425.5
ENST00000311048.11
zinc finger protein 431
chr11_-_114400417 0.09 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr2_+_169066994 0.09 ENST00000357546.6
ENST00000432060.6
dehydrogenase/reductase 9
chr6_-_89217339 0.09 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr12_+_12725897 0.09 ENST00000326765.10
apolipoprotein L domain containing 1
chr5_-_149944744 0.09 ENST00000255266.10
ENST00000617647.4
ENST00000613228.1
phosphodiesterase 6A
chr12_-_102480604 0.09 ENST00000392905.7
insulin like growth factor 1
chr5_-_16916400 0.09 ENST00000513882.5
myosin X
chr17_-_4263847 0.08 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chr2_-_174764407 0.08 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr4_+_185204237 0.08 ENST00000618785.4
ENST00000504273.5
sorting nexin 25
chr6_+_63521738 0.08 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr20_-_10420737 0.08 ENST00000649912.1
novel protein
chr11_+_24496988 0.08 ENST00000336930.11
leucine zipper protein 2
chr1_+_13061158 0.08 ENST00000681473.1
heterogeneous nuclear ribonucleoprotein C like 3
chr1_-_13165631 0.08 ENST00000323770.8
heterogeneous nuclear ribonucleoprotein C like 4

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0034699 transforming growth factor beta receptor complex assembly(GO:0007181) response to luteinizing hormone(GO:0034699)
0.3 4.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.7 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 2.1 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.2 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.5 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 1.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:1904397 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.7 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 1.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.2 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0071284 copper ion export(GO:0060003) cellular response to cobalt ion(GO:0071279) cellular response to lead ion(GO:0071284)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0046219 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 0.4 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.9 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.0 GO:0014873 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.0 GO:0097545 axonemal outer doublet(GO:0097545)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 2.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.1 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 4.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 4.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis