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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for E2F4

Z-value: 1.45

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Transcription factors associated with E2F4

Gene Symbol Gene ID Gene Info
ENSG00000205250.9 E2F transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F4hg38_v1_chr16_+_67192116_671922250.801.6e-02Click!

Activity profile of E2F4 motif

Sorted Z-values of E2F4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_23821275 1.12 ENST00000380110.8
ELAV like RNA binding protein 2
chr16_+_68645290 0.77 ENST00000264012.9
cadherin 3
chr19_+_39196956 0.75 ENST00000339852.5
NCCRP1, F-box associated domain containing
chr9_-_23821809 0.71 ENST00000544538.5
ELAV like RNA binding protein 2
chr16_+_788614 0.65 ENST00000262315.14
ENST00000455171.6
ENST00000317063.10
chromosome transmission fidelity factor 18
chr2_+_172427662 0.57 ENST00000264107.12
ENST00000458358.5
integrin subunit alpha 6
chr5_-_60844185 0.55 ENST00000505959.5
ELOVL fatty acid elongase 7
chr11_+_62856004 0.54 ENST00000680729.1
solute carrier family 3 member 2
chr13_+_32315468 0.52 ENST00000530893.6
ENST00000380152.8
BRCA2 DNA repair associated
chr12_-_84912783 0.52 ENST00000680892.1
ENST00000266682.10
ENST00000680714.1
ENST00000552192.5
solute carrier family 6 member 15
chr17_+_40287861 0.52 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
cell division cycle 6
chr2_+_172427573 0.51 ENST00000684293.1
ENST00000409080.6
ENST00000442250.6
integrin subunit alpha 6
chr19_-_6424802 0.50 ENST00000600480.2
KH-type splicing regulatory protein
chr10_-_68471882 0.49 ENST00000551118.6
DNA replication helicase/nuclease 2
chr5_-_150302884 0.49 ENST00000328668.8
arylsulfatase family member I
chr1_+_59814939 0.49 ENST00000371208.5
hook microtubule tethering protein 1
chr11_+_62856072 0.48 ENST00000377890.6
ENST00000681467.1
ENST00000538084.2
ENST00000681569.1
ENST00000377891.6
ENST00000680725.1
ENST00000377889.6
solute carrier family 3 member 2
chr8_-_123396412 0.47 ENST00000287394.10
ATPase family AAA domain containing 2
chr10_-_68471911 0.46 ENST00000358410.8
ENST00000399180.3
DNA replication helicase/nuclease 2
chr1_+_43933277 0.46 ENST00000414809.7
artemin
chr1_-_25859352 0.46 ENST00000374298.4
ENST00000538789.5
aurora kinase A and ninein interacting protein
chr16_+_2460086 0.45 ENST00000569496.5
ENST00000567489.5
ENST00000361837.9
ENST00000563531.5
ENST00000483320.5
tubulin epsilon and delta complex 2
chr1_+_43933794 0.44 ENST00000372359.10
ENST00000498139.6
ENST00000491846.5
artemin
chr22_+_44752552 0.43 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
Rho GTPase activating protein 8
chr2_+_218710931 0.43 ENST00000442769.5
ENST00000424644.1
tubulin tyrosine ligase like 4
chr11_+_62856149 0.42 ENST00000535296.5
solute carrier family 3 member 2
chr4_+_84583037 0.41 ENST00000295887.6
CDP-diacylglycerol synthase 1
chr8_+_123072667 0.41 ENST00000519418.5
ENST00000287380.6
ENST00000327098.9
ENST00000522420.5
ENST00000521676.5
TBC1 domain family member 31
chr2_-_70553638 0.41 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr8_-_144444406 0.41 ENST00000409379.8
tonsoku like, DNA repair protein
chr19_-_6424772 0.40 ENST00000619396.4
ENST00000398148.7
KH-type splicing regulatory protein
chr15_+_90184912 0.40 ENST00000561085.1
ENST00000332496.10
semaphorin 4B
chr3_+_10026409 0.39 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr15_+_90717321 0.39 ENST00000355112.8
ENST00000681142.1
ENST00000648453.1
ENST00000560509.5
BLM RecQ like helicase
chr4_+_177309866 0.39 ENST00000264596.4
nei like DNA glycosylase 3
chr2_-_234497035 0.39 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr13_-_75482114 0.38 ENST00000377625.6
ENST00000431480.6
TBC1 domain family member 4
chr13_-_75482151 0.37 ENST00000377636.8
TBC1 domain family member 4
chr16_+_71626175 0.37 ENST00000268485.8
ENST00000565261.1
ENST00000299952.4
MARVEL domain containing 3
chr1_-_35769928 0.37 ENST00000373220.7
ENST00000520551.1
claspin
chr10_-_97401277 0.37 ENST00000315563.10
ENST00000370992.9
ENST00000414986.5
ribosomal RNA processing 12 homolog
chr1_+_28518136 0.35 ENST00000373832.5
ENST00000373831.7
regulator of chromosome condensation 1
chr15_-_50355100 0.35 ENST00000543881.5
GA binding protein transcription factor subunit beta 1
chr1_-_197146688 0.35 ENST00000294732.11
assembly factor for spindle microtubules
chr17_-_43125300 0.34 ENST00000497488.1
ENST00000354071.7
ENST00000489037.1
ENST00000470026.5
ENST00000644555.1
ENST00000586385.5
ENST00000591534.5
ENST00000591849.5
BRCA1 DNA repair associated
chr19_+_7888499 0.33 ENST00000618098.4
ENST00000306708.11
ENST00000600345.1
ENST00000598224.5
leucine rich repeat containing 8 VRAC subunit E
chr1_-_35769958 0.32 ENST00000251195.9
ENST00000318121.8
claspin
chr1_-_197146620 0.32 ENST00000367409.9
ENST00000680265.1
assembly factor for spindle microtubules
chr22_+_19479826 0.32 ENST00000437685.6
ENST00000263201.7
ENST00000404724.7
cell division cycle 45
chr12_-_57078784 0.32 ENST00000300128.9
nuclear envelope integral membrane protein 1
chr14_-_53953415 0.32 ENST00000559501.1
ENST00000558984.1
bone morphogenetic protein 4
chr2_+_218710821 0.32 ENST00000392102.6
ENST00000457313.5
ENST00000415717.5
tubulin tyrosine ligase like 4
chr8_+_103500696 0.31 ENST00000666250.1
ENST00000668113.1
ENST00000504942.6
ENST00000632716.1
regulating synaptic membrane exocytosis 2
chr2_+_10122315 0.30 ENST00000360566.6
ribonucleotide reductase regulatory subunit M2
chr17_+_36534980 0.30 ENST00000614443.2
ENST00000619326.1
phosphatidylinositol glycan anchor biosynthesis class W
chr12_-_57078739 0.30 ENST00000379391.7
nuclear envelope integral membrane protein 1
chr17_-_43125353 0.30 ENST00000476777.5
ENST00000491747.6
ENST00000478531.5
ENST00000357654.9
ENST00000477152.5
ENST00000618469.1
ENST00000352993.7
ENST00000493795.5
ENST00000493919.5
BRCA1 DNA repair associated
chr2_+_156436423 0.30 ENST00000540309.5
glycerol-3-phosphate dehydrogenase 2
chr17_-_36534927 0.30 ENST00000610930.4
myosin XIX
chr9_+_504675 0.30 ENST00000382297.7
ENST00000674102.1
ENST00000619269.4
KN motif and ankyrin repeat domains 1
chr9_-_122228845 0.30 ENST00000394319.8
ENST00000340587.7
LIM homeobox 6
chr7_-_100101333 0.30 ENST00000303887.10
minichromosome maintenance complex component 7
chr11_+_45922640 0.29 ENST00000401752.6
ENST00000325468.9
LARGE xylosyl- and glucuronyltransferase 2
chr13_+_32315071 0.29 ENST00000544455.6
BRCA2 DNA repair associated
chr4_-_112636858 0.29 ENST00000503172.5
ENST00000505019.6
ENST00000309071.9
zinc finger GRF-type containing 1
chr15_+_90201301 0.29 ENST00000411539.6
semaphorin 4B
chr1_+_173824694 0.29 ENST00000647645.1
aspartyl-tRNA synthetase 2, mitochondrial
chr3_-_51499950 0.29 ENST00000423656.5
ENST00000504652.5
ENST00000684031.1
DDB1 and CUL4 associated factor 1
chr1_+_173824626 0.28 ENST00000648960.1
ENST00000648807.1
ENST00000649067.1
ENST00000649689.2
aspartyl-tRNA synthetase 2, mitochondrial
chrX_-_14873027 0.28 ENST00000452869.1
ENST00000398334.5
ENST00000650831.1
ENST00000324138.7
FA complementation group B
chr4_+_153344671 0.28 ENST00000240488.8
meiotic nuclear divisions 1
chr16_+_71626149 0.28 ENST00000567566.1
MARVEL domain containing 3
chr18_+_31498168 0.28 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr1_+_28518266 0.28 ENST00000411533.5
regulator of chromosome condensation 1
chr17_-_43125450 0.28 ENST00000494123.5
ENST00000468300.5
ENST00000471181.7
ENST00000652672.1
BRCA1 DNA repair associated
chr2_+_230712817 0.28 ENST00000258418.10
calcium binding protein 39
chr21_-_43076362 0.28 ENST00000359624.7
ENST00000352178.9
cystathionine beta-synthase
chr12_-_12562344 0.28 ENST00000228862.3
dual specificity phosphatase 16
chr8_+_47960883 0.28 ENST00000648407.1
ENST00000649838.1
ENST00000649919.1
ENST00000262105.6
ENST00000649973.1
minichromosome maintenance complex component 4
chr5_-_43313403 0.28 ENST00000325110.11
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr4_+_153344633 0.27 ENST00000622785.4
meiotic nuclear divisions 1
chr2_+_188292814 0.27 ENST00000409580.5
ENST00000409637.7
GULP PTB domain containing engulfment adaptor 1
chr5_+_892844 0.27 ENST00000166345.8
thyroid hormone receptor interactor 13
chr6_-_20212403 0.27 ENST00000324607.8
membrane bound O-acyltransferase domain containing 1
chr17_-_13017952 0.27 ENST00000578071.1
ENST00000426905.7
ENST00000395962.6
ENST00000338034.9
ENST00000583371.5
elaC ribonuclease Z 2
chr6_+_31739948 0.26 ENST00000375755.8
ENST00000425703.5
ENST00000375750.9
ENST00000375703.7
ENST00000375740.7
mutS homolog 5
chr15_-_50355173 0.26 ENST00000558970.2
ENST00000380877.8
ENST00000396464.7
ENST00000560825.5
GA binding protein transcription factor subunit beta 1
chr5_-_176610104 0.25 ENST00000303991.5
G protein regulated inducer of neurite outgrowth 1
chr19_+_18173804 0.25 ENST00000407280.4
IFI30 lysosomal thiol reductase
chr1_+_11273188 0.25 ENST00000376810.6
UbiA prenyltransferase domain containing 1
chr7_-_100100716 0.25 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr21_-_6468040 0.25 ENST00000618024.4
ENST00000617706.4
cystathionine beta-synthase like
chr19_-_19628197 0.25 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr1_+_229626170 0.25 ENST00000258243.7
URB2 ribosome biogenesis homolog
chr13_+_33818122 0.25 ENST00000380071.8
replication factor C subunit 3
chr2_+_188292771 0.24 ENST00000359135.7
GULP PTB domain containing engulfment adaptor 1
chr12_-_77065526 0.24 ENST00000547316.1
ENST00000416496.6
ENST00000550669.5
ENST00000322886.12
E2F transcription factor 7
chr2_+_27217361 0.24 ENST00000264705.9
ENST00000403525.5
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr5_-_43313473 0.24 ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr5_+_157460173 0.24 ENST00000435489.7
ENST00000311946.8
NIPA like domain containing 4
chr15_-_50355150 0.23 ENST00000220429.12
ENST00000429662.6
GA binding protein transcription factor subunit beta 1
chr18_+_36187483 0.23 ENST00000261326.6
molybdenum cofactor sulfurase
chr6_+_135181268 0.23 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr19_+_5623073 0.23 ENST00000588852.2
ENST00000292123.9
ENST00000592224.5
ENST00000454510.5
scaffold attachment factor B
chr15_+_89243945 0.23 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FA complementation group I
chr10_+_102152169 0.23 ENST00000405356.5
nucleolar and coiled-body phosphoprotein 1
chr15_+_40695423 0.23 ENST00000526763.6
ENST00000532743.6
RAD51 recombinase
chr5_+_150357629 0.23 ENST00000650162.1
ENST00000377797.7
ENST00000445265.6
ENST00000323668.11
ENST00000643257.2
ENST00000646961.1
ENST00000513538.2
ENST00000439160.6
ENST00000394269.7
ENST00000427724.7
ENST00000504761.6
ENST00000513346.5
ENST00000515516.1
treacle ribosome biogenesis factor 1
chr1_+_15409858 0.23 ENST00000375980.9
EF-hand domain family member D2
chr10_-_119080794 0.22 ENST00000369144.8
ENST00000541549.2
eukaryotic translation initiation factor 3 subunit A
chr12_+_4909895 0.22 ENST00000638821.1
ENST00000382545.5
novel transcript, sense overlapping KCNA1
potassium voltage-gated channel subfamily A member 1
chr15_+_40695129 0.22 ENST00000423169.6
ENST00000557850.5
ENST00000382643.7
ENST00000267868.8
ENST00000645673.2
RAD51 recombinase
chrX_-_130903187 0.22 ENST00000432489.5
ENST00000394363.6
ENST00000338144.8
ecto-NOX disulfide-thiol exchanger 2
chr6_+_135181323 0.22 ENST00000367814.8
MYB proto-oncogene, transcription factor
chr11_+_82901698 0.22 ENST00000524921.5
ENST00000528759.5
ENST00000525361.5
ENST00000532764.5
ENST00000532589.5
ENST00000533655.6
ENST00000525388.5
DNA damage induced apoptosis suppressor
chr13_+_33818063 0.22 ENST00000434425.5
replication factor C subunit 3
chr8_+_127736220 0.22 ENST00000524013.2
ENST00000621592.8
MYC proto-oncogene, bHLH transcription factor
chrX_-_130903224 0.22 ENST00000370935.5
ecto-NOX disulfide-thiol exchanger 2
chr11_+_68460712 0.21 ENST00000528635.5
ENST00000533127.5
ENST00000529907.5
ENST00000529344.5
ENST00000534534.5
ENST00000524845.5
ENST00000393800.7
ENST00000265637.8
ENST00000524904.5
ENST00000393801.7
ENST00000265636.9
ENST00000529710.5
protein phosphatase 6 regulatory subunit 3
chr8_+_127736046 0.21 ENST00000641036.1
ENST00000377970.6
MYC proto-oncogene, bHLH transcription factor
chr18_+_50375037 0.21 ENST00000398452.6
ENST00000417656.6
ENST00000488454.5
ENST00000285116.8
ENST00000494518.1
spindle and kinetochore associated complex subunit 1
chr18_-_21703688 0.21 ENST00000584464.1
ENST00000578270.5
abhydrolase domain containing 3, phospholipase
chr6_-_52284677 0.21 ENST00000596288.7
ENST00000616552.4
ENST00000229854.12
ENST00000419835.8
minichromosome maintenance complex component 3
chr17_+_7440738 0.20 ENST00000575398.5
ENST00000575082.5
fibroblast growth factor 11
chr2_+_10123171 0.20 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr9_+_128947687 0.20 ENST00000372577.2
nucleoporin 188
chr8_-_144517785 0.20 ENST00000617875.6
ENST00000621189.4
RecQ like helicase 4
chr19_+_797443 0.20 ENST00000356948.11
ENST00000394601.8
ENST00000589575.5
ENST00000587191.3
polypyrimidine tract binding protein 1
chr4_-_119628007 0.20 ENST00000420633.1
ENST00000394439.5
phosphodiesterase 5A
chr21_-_33542841 0.20 ENST00000381831.7
ENST00000381839.7
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr8_+_35235467 0.20 ENST00000404895.7
unc-5 netrin receptor D
chr20_+_1894733 0.20 ENST00000356025.7
signal regulatory protein alpha
chr21_-_32279012 0.19 ENST00000290130.4
MIS18 kinetochore protein A
chr4_+_127880876 0.19 ENST00000270861.10
ENST00000515069.5
ENST00000513090.5
ENST00000507249.5
polo like kinase 4
chr2_+_156436345 0.19 ENST00000438166.7
glycerol-3-phosphate dehydrogenase 2
chrX_+_21374476 0.19 ENST00000644585.1
connector enhancer of kinase suppressor of Ras 2
chr7_+_104328603 0.19 ENST00000401970.3
ENST00000424859.7
LHFPL tetraspan subfamily member 3
chr2_+_158456939 0.19 ENST00000389759.8
ENST00000628904.2
ENST00000389757.7
plakophilin 4
chr6_+_96924720 0.19 ENST00000369261.9
kelch like family member 32
chrX_-_40735476 0.19 ENST00000324817.6
mediator complex subunit 14
chr1_+_151282262 0.19 ENST00000336715.11
ENST00000324048.9
zinc finger protein 687
chr9_+_21802628 0.19 ENST00000644715.2
ENST00000460874.6
ENST00000580900.5
methylthioadenosine phosphorylase
chr9_-_137302264 0.19 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chr14_+_56118404 0.18 ENST00000267460.9
pellino E3 ubiquitin protein ligase family member 2
chr9_+_131096476 0.18 ENST00000372309.7
ENST00000247291.8
ENST00000372302.5
ENST00000372300.5
ENST00000372298.1
allograft inflammatory factor 1 like
chr15_+_51829644 0.18 ENST00000308580.12
tropomodulin 3
chr1_+_26921715 0.18 ENST00000321265.10
nuclear distribution C, dynein complex regulator
chr19_-_47471886 0.18 ENST00000236877.11
ENST00000597014.1
solute carrier family 8 member A2
chr8_+_123768431 0.17 ENST00000334705.12
ENST00000521166.5
family with sequence similarity 91 member A1
chr11_-_78574759 0.17 ENST00000281038.10
ENST00000529571.1
asparaginyl-tRNA synthetase 2, mitochondrial
chr19_+_4279285 0.17 ENST00000599689.1
Src homology 2 domain containing transforming protein D
chr9_-_35079923 0.17 ENST00000378643.8
ENST00000448890.1
FA complementation group G
chr19_-_5622768 0.17 ENST00000252542.9
scaffold attachment factor B2
chr3_-_33718207 0.17 ENST00000359576.9
ENST00000682230.1
ENST00000399362.8
cytoplasmic linker associated protein 2
chr10_-_43396831 0.17 ENST00000443950.6
heterogeneous nuclear ribonucleoprotein F
chr3_-_33718049 0.17 ENST00000468888.6
cytoplasmic linker associated protein 2
chr4_-_119627631 0.17 ENST00000264805.9
phosphodiesterase 5A
chr4_+_39459039 0.17 ENST00000509519.5
ENST00000640888.2
ENST00000424936.6
ENST00000381846.2
ENST00000513731.6
lipoic acid synthetase
chr22_+_41092585 0.17 ENST00000263253.9
E1A binding protein p300
chr1_+_64745089 0.17 ENST00000294428.7
ENST00000371072.8
ribonucleoprotein, PTB binding 2
chr9_-_27573653 0.16 ENST00000379995.1
ENST00000647196.1
ENST00000619707.5
ENST00000379997.7
C9orf72-SMCR8 complex subunit
chr4_+_39459069 0.16 ENST00000261434.8
ENST00000340169.7
ENST00000638451.1
ENST00000640349.1
lipoic acid synthetase
chr16_-_4351257 0.16 ENST00000577031.5
presequence translocase associated motor 16
chr1_-_226309198 0.16 ENST00000481685.1
lin-9 DREAM MuvB core complex component
chr11_-_119095456 0.16 ENST00000530167.1
H2A.X variant histone
chr11_-_65084024 0.16 ENST00000275517.8
ENST00000404147.3
cell division cycle associated 5
chr6_-_70957029 0.16 ENST00000230053.11
beta-1,3-glucuronyltransferase 2
chr1_-_26046111 0.16 ENST00000374278.7
ENST00000374276.4
solute carrier family 30 member 2
chr18_+_62715526 0.16 ENST00000262719.10
PH domain and leucine rich repeat protein phosphatase 1
chr5_-_892765 0.16 ENST00000467963.6
bromodomain containing 9
chr19_-_10333512 0.16 ENST00000617231.5
ENST00000611074.4
ENST00000615032.4
ribonucleoprotein, PTB binding 1
chr19_-_47471847 0.16 ENST00000594353.1
ENST00000542837.2
solute carrier family 8 member A2
chr6_+_96924614 0.16 ENST00000536676.5
ENST00000539200.5
ENST00000544166.5
kelch like family member 32
chr12_+_93572664 0.16 ENST00000551556.2
suppressor of cytokine signaling 2
chr3_+_100401530 0.16 ENST00000383693.8
leukemia NUP98 fusion partner 1
chr16_+_649351 0.16 ENST00000293879.9
WD repeat domain 90
chr17_-_7294592 0.16 ENST00000007699.10
Y-box binding protein 2
chr3_+_100401592 0.16 ENST00000489752.1
leukemia NUP98 fusion partner 1
chr2_+_68157877 0.16 ENST00000263657.7
partner of NOB1 homolog
chr7_+_21543020 0.16 ENST00000409508.8
ENST00000620169.4
ENST00000328843.10
dynein axonemal heavy chain 11
chr5_+_14664653 0.15 ENST00000284274.5
OTU deubiquitinase with linear linkage specificity
chr19_-_46746421 0.15 ENST00000263280.11
striatin 4
chr16_+_649319 0.15 ENST00000549091.5
WD repeat domain 90
chr6_+_31897775 0.15 ENST00000469372.5
ENST00000497706.5
complement C2
chr15_-_74695987 0.15 ENST00000563009.5
ENST00000568176.5
ENST00000566243.5
ENST00000566219.1
ENST00000426797.7
ENST00000315127.9
ENST00000566119.5
enhancer of mRNA decapping 3
chr4_+_127782270 0.15 ENST00000508549.5
ENST00000296464.9
heat shock protein family A (Hsp70) member 4 like
chr1_-_155978144 0.15 ENST00000313695.11
ENST00000497907.5
Rho/Rac guanine nucleotide exchange factor 2
chr1_+_10032832 0.15 ENST00000253251.12
ENST00000672724.1
ENST00000343090.11
ubiquitination factor E4B
chr15_+_41559189 0.15 ENST00000263798.8
TYRO3 protein tyrosine kinase
chr6_-_11044275 0.15 ENST00000354666.4
ELOVL fatty acid elongase 2
chr12_+_49323236 0.15 ENST00000549275.5
ENST00000551245.5
ENST00000380327.9
ENST00000548311.5
ENST00000257909.8
ENST00000550346.5
ENST00000550709.5
ENST00000549534.1
ENST00000547807.5
ENST00000551567.1
trophinin associated protein
chr16_-_23557331 0.15 ENST00000563232.1
ENST00000449606.7
glutamyl-tRNA synthetase 2, mitochondrial
chr16_-_2214776 0.15 ENST00000333503.8
phosphoglycolate phosphatase
chr7_-_130205348 0.15 ENST00000462753.5
ENST00000471077.2
ENST00000473456.5
ENST00000397622.7
transmembrane protein 209
chr1_-_85048437 0.14 ENST00000341115.8
ENST00000370587.5
ENST00000370589.7
mucolipin TRP cation channel 3
chrX_+_150983299 0.14 ENST00000325307.12
high mobility group box 3
chrX_-_15675012 0.14 ENST00000650271.1
collectrin, amino acid transport regulator
chr18_-_80247348 0.14 ENST00000470488.2
ENST00000353265.8
par-6 family cell polarity regulator gamma
chr11_-_119101814 0.14 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr22_-_38398480 0.14 ENST00000400206.7
TPTEP2-CSNK1E readthrough

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.3 0.8 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908)
0.3 1.3 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.2 0.7 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 1.4 GO:0060356 leucine import(GO:0060356)
0.2 1.0 GO:1902990 DNA replication, removal of RNA primer(GO:0043137) mitochondrial DNA repair(GO:0043504) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 0.6 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.9 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.2 0.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 1.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.5 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.4 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 0.4 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.3 GO:2000005 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.5 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.1 0.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.3 GO:0070650 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0034414 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 1.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0015820 leucine transport(GO:0015820)
0.1 1.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.8 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.4 GO:0072757 cellular response to camptothecin(GO:0072757)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.1 0.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.9 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.3 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 0.7 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.3 GO:0003164 His-Purkinje system development(GO:0003164) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.3 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 1.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.3 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:1905069 nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0060068 vagina development(GO:0060068) neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.0 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.3 0.8 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.2 0.9 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 1.6 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.7 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.6 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.0 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.2 0.5 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.3 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.5 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.3 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 0.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.7 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.5 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.4 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.2 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.0 0.2 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 1.0 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription