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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for EMX2

Z-value: 0.61

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Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
EMX2
ENSG00000170370.12 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX2hg38_v1_chr10_+_117542416_117542445,
hg38_v1_chr10_+_117543567_117543658,
hg38_v1_chr10_+_117542721_117542754		0.265.4e-01Click!

Activity profile of EMX2 motif

Sorted Z-values of EMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91180365 0.87 ENST00000547937.5
DCN
decorin
chr6_+_72216442 0.86 ENST00000425662.6
ENST00000453976.6
RIMS1
regulating synaptic membrane exocytosis 1
chr11_-_63608542 0.80 ENST00000540943.1
PLAAT3
phospholipase A and acyltransferase 3
chr10_-_91633057 0.57 ENST00000238994.6
PPP1R3C
protein phosphatase 1 regulatory subunit 3C
chr5_-_76623391 0.56 ENST00000296641.5
ENST00000504899.1
F2RL2
coagulation factor II thrombin receptor like 2
chr9_-_76906041 0.52 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
PRUNE2
prune homolog 2 with BCH domain
chr5_-_111976925 0.49 ENST00000395634.7
NREP
neuronal regeneration related protein
chr4_+_70050431 0.45 ENST00000511674.5
ENST00000246896.8
HTN1
histatin 1
chr10_-_77638369 0.44 ENST00000372443.6
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr16_+_86566821 0.44 ENST00000649859.1
FOXC2
forkhead box C2
chr2_-_206218024 0.39 ENST00000407325.6
ENST00000612892.4
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr8_-_13276491 0.39 ENST00000512044.6
DLC1
DLC1 Rho GTPase activating protein
chr10_-_77637902 0.39 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr4_-_137532452 0.37 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr10_-_20897288 0.34 ENST00000377122.9
NEBL
nebulette
chr10_-_77637721 0.33 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr10_-_77637789 0.33 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr19_+_49513353 0.32 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr6_+_72212802 0.32 ENST00000401910.7
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_189179754 0.31 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr2_-_98663464 0.31 ENST00000414521.6
MGAT4A
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr6_+_72212887 0.28 ENST00000523963.5
RIMS1
regulating synaptic membrane exocytosis 1
chr17_+_1771688 0.28 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin family F member 1
chr1_+_77918128 0.28 ENST00000342754.5
NEXN
nexilin F-actin binding protein
chr6_+_101181254 0.27 ENST00000682090.1
ENST00000421544.6
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr12_+_59689337 0.25 ENST00000261187.8
SLC16A7
solute carrier family 16 member 7
chr6_+_135851681 0.25 ENST00000308191.11
PDE7B
phosphodiesterase 7B
chr5_+_141412979 0.24 ENST00000612503.1
ENST00000398610.3
PCDHGA10
protocadherin gamma subfamily A, 10
chr6_-_29375291 0.23 ENST00000396806.3
OR12D3
olfactory receptor family 12 subfamily D member 3
chr7_+_90709530 0.22 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr4_-_88697810 0.22 ENST00000323061.7
NAP1L5
nucleosome assembly protein 1 like 5
chr1_+_78649818 0.22 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr8_+_69492793 0.21 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
SULF1
sulfatase 1
chr1_+_78004930 0.21 ENST00000370763.6
DNAJB4
DnaJ heat shock protein family (Hsp40) member B4
chr3_+_111674654 0.21 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
PLCXD2
phosphatidylinositol specific phospholipase C X domain containing 2
chr9_-_16728165 0.21 ENST00000603713.5
ENST00000603313.5
BNC2
basonuclin 2
chr16_+_85027735 0.19 ENST00000258180.7
ENST00000538274.5
KIAA0513
KIAA0513
chr10_+_15032193 0.19 ENST00000428897.5
ENST00000413672.5
OLAH
oleoyl-ACP hydrolase
chr4_+_55346213 0.18 ENST00000679836.1
ENST00000264228.9
ENST00000679707.1
SRD5A3
ENSG00000288695.1
steroid 5 alpha-reductase 3
novel protein, SRD5A3-RP11-177J6.1 readthrough
chr12_+_18242955 0.18 ENST00000676171.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr7_+_90709231 0.17 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr10_+_89332484 0.17 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
IFIT3
interferon induced protein with tetratricopeptide repeats 3
chr1_+_192809031 0.16 ENST00000235382.7
RGS2
regulator of G protein signaling 2
chr21_-_30497160 0.15 ENST00000334058.3
KRTAP19-4
keratin associated protein 19-4
chr7_+_138460238 0.15 ENST00000343526.9
TRIM24
tripartite motif containing 24
chr17_-_69141878 0.15 ENST00000590645.1
ENST00000284425.7
ABCA6
ATP binding cassette subfamily A member 6
chr11_+_66509079 0.15 ENST00000419755.3
ENSG00000256349.1
novel protein
chr1_+_177170916 0.15 ENST00000361539.5
BRINP2
BMP/retinoic acid inducible neural specific 2
chr1_-_60073750 0.14 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr2_+_201132958 0.14 ENST00000479953.6
ENST00000340870.6
CFLAR
CASP8 and FADD like apoptosis regulator
chr1_+_152878312 0.14 ENST00000368765.4
SMCP
sperm mitochondria associated cysteine rich protein
chr2_+_201132928 0.14 ENST00000462763.5
CFLAR
CASP8 and FADD like apoptosis regulator
chrX_+_18425597 0.14 ENST00000623535.2
ENST00000674046.1
CDKL5
cyclin dependent kinase like 5
chr14_+_34993240 0.14 ENST00000677647.1
SRP54
signal recognition particle 54
chr11_-_124800630 0.13 ENST00000239614.8
ENST00000674284.1
MSANTD2
Myb/SANT DNA binding domain containing 2
chr1_+_174875505 0.13 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr3_+_131026844 0.13 ENST00000510769.5
ENST00000383366.9
ENST00000510688.5
ENST00000511262.5
NEK11
NIMA related kinase 11
chr9_-_96778053 0.13 ENST00000375231.5
ENST00000223428.9
ZNF510
zinc finger protein 510
chr5_+_55160161 0.13 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
GPX8
glutathione peroxidase 8 (putative)
chr7_-_44848021 0.12 ENST00000349299.7
ENST00000521529.5
ENST00000350771.7
ENST00000222690.10
ENST00000381124.9
ENST00000437072.5
ENST00000446531.1
ENST00000308153.9
H2AZ2
H2A.Z variant histone 2
chr5_-_132227472 0.12 ENST00000428369.6
P4HA2
prolyl 4-hydroxylase subunit alpha 2
chr8_-_132675567 0.12 ENST00000519595.5
LRRC6
leucine rich repeat containing 6
chr14_-_80231052 0.12 ENST00000557010.5
DIO2
iodothyronine deiodinase 2
chrX_+_55717733 0.12 ENST00000414239.5
ENST00000374941.9
RRAGB
Ras related GTP binding B
chr3_+_72888031 0.11 ENST00000389617.9
GXYLT2
glucoside xylosyltransferase 2
chr2_+_201132769 0.11 ENST00000494258.5
CFLAR
CASP8 and FADD like apoptosis regulator
chr9_+_72577369 0.11 ENST00000651183.1
TMC1
transmembrane channel like 1
chr4_+_87832917 0.11 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr2_+_109794296 0.11 ENST00000430736.5
ENST00000016946.8
ENST00000441344.1
RGPD5
RANBP2 like and GRIP domain containing 5
chr5_+_148394712 0.11 ENST00000513826.1
FBXO38
F-box protein 38
chrX_+_55717796 0.11 ENST00000262850.7
RRAGB
Ras related GTP binding B
chr5_+_75611182 0.11 ENST00000672850.1
ENST00000672844.1
ANKDD1B
ankyrin repeat and death domain containing 1B
chr11_-_125111708 0.11 ENST00000531909.5
ENST00000529530.1
TMEM218
transmembrane protein 218
chr1_+_244835616 0.11 ENST00000366528.3
ENST00000411948.7
COX20
cytochrome c oxidase assembly factor COX20
chr5_-_88823763 0.11 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
MEF2C
myocyte enhancer factor 2C
chr5_-_180861248 0.10 ENST00000502412.2
ENST00000512132.5
ENST00000506439.5
ZFP62
ZFP62 zinc finger protein
chr14_-_105242605 0.10 ENST00000549655.5
BRF1
BRF1 RNA polymerase III transcription initiation factor subunit
chr16_+_69565958 0.10 ENST00000349945.7
ENST00000354436.6
NFAT5
nuclear factor of activated T cells 5
chr3_+_40477107 0.10 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
ZNF619
zinc finger protein 619
chr4_+_155903688 0.10 ENST00000536354.3
TDO2
tryptophan 2,3-dioxygenase
chr17_-_36264514 0.10 ENST00000618620.4
ENST00000621034.1
TBC1D3I
TBC1 domain family member 3I
chr5_+_134967901 0.10 ENST00000282611.8
CATSPER3
cation channel sperm associated 3
chr16_-_30091226 0.10 ENST00000279386.6
ENST00000627355.2
TBX6
T-box transcription factor 6
chr3_-_49429304 0.10 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
ENSG00000283189.2
NICN1
novel protein
nicolin 1
chr10_-_122845850 0.10 ENST00000392790.6
CUZD1
CUB and zona pellucida like domains 1
chrX_+_136648138 0.10 ENST00000370629.7
CD40LG
CD40 ligand
chr9_+_128566741 0.10 ENST00000630866.1
SPTAN1
spectrin alpha, non-erythrocytic 1
chr9_+_72577788 0.09 ENST00000645208.2
TMC1
transmembrane channel like 1
chr1_+_86547070 0.09 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr3_-_49429252 0.09 ENST00000615713.4
NICN1
nicolin 1
chrX_+_136648214 0.09 ENST00000370628.2
CD40LG
CD40 ligand
chr3_-_127736329 0.09 ENST00000398101.7
MGLL
monoglyceride lipase
chr1_-_19923617 0.09 ENST00000375116.3
PLA2G2E
phospholipase A2 group IIE
chr4_-_88284616 0.09 ENST00000508256.5
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr18_+_34710307 0.09 ENST00000679796.1
DTNA
dystrobrevin alpha
chr4_-_88284590 0.09 ENST00000510548.6
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr3_-_155293665 0.08 ENST00000489090.2
STRIT1
small transmembrane regulator of ion transport 1
chr6_-_26234978 0.08 ENST00000244534.7
H1-3
H1.3 linker histone, cluster member
chr2_+_201132872 0.08 ENST00000470178.6
CFLAR
CASP8 and FADD like apoptosis regulator
chr5_+_42548043 0.08 ENST00000618088.4
ENST00000612382.4
GHR
growth hormone receptor
chr19_-_51417791 0.08 ENST00000353836.9
SIGLEC10
sialic acid binding Ig like lectin 10
chr4_-_39032922 0.08 ENST00000344606.6
TMEM156
transmembrane protein 156
chr20_-_35411963 0.08 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
UQCC1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr17_+_38127951 0.08 ENST00000621587.2
TBC1D3E
TBC1 domain family member 3E
chr17_+_38003976 0.08 ENST00000616101.4
TBC1D3D
TBC1 domain family member 3D
chr17_-_37989048 0.08 ENST00000617678.2
ENST00000612727.5
TBC1D3L
TBC1 domain family member 3L
chr12_-_11134644 0.08 ENST00000539585.1
TAS2R30
taste 2 receptor member 30
chr6_+_28124596 0.08 ENST00000340487.5
ZSCAN16
zinc finger and SCAN domain containing 16
chr17_-_15341577 0.08 ENST00000543896.1
ENST00000395930.6
ENST00000539245.5
ENST00000539316.1
TEKT3
tektin 3
chr21_-_7825797 0.08 ENST00000617668.2
KCNE1B
potassium voltage-gated channel subfamily E regulatory subunit 1B
chr5_-_177780633 0.08 ENST00000513554.5
ENST00000440605.7
FAM153A
family with sequence similarity 153 member A
chr17_-_445939 0.08 ENST00000329099.4
RFLNB
refilin B
chr14_+_61697622 0.08 ENST00000539097.2
HIF1A
hypoxia inducible factor 1 subunit alpha
chr1_+_224183197 0.08 ENST00000323699.9
DEGS1
delta 4-desaturase, sphingolipid 1
chrX_+_77910656 0.07 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATP7A
PGK1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr15_+_64387828 0.07 ENST00000261884.8
TRIP4
thyroid hormone receptor interactor 4
chr19_-_34773184 0.07 ENST00000588760.1
ENST00000329285.13
ENST00000587354.6
ZNF599
zinc finger protein 599
chr17_-_76141240 0.07 ENST00000322957.7
FOXJ1
forkhead box J1
chr15_-_19988117 0.07 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr10_+_100462969 0.07 ENST00000343737.6
WNT8B
Wnt family member 8B
chr2_-_110577101 0.07 ENST00000330331.9
ENST00000446930.1
ENST00000329516.8
RGPD6
RANBP2 like and GRIP domain containing 6
chr5_+_160009113 0.07 ENST00000522793.5
ENST00000682719.1
ENST00000684137.1
ENST00000683219.1
ENST00000684018.1
ENST00000231238.10
ENST00000682131.1
TTC1
tetratricopeptide repeat domain 1
chr20_+_15196834 0.07 ENST00000402914.5
MACROD2
mono-ADP ribosylhydrolase 2
chr8_-_25424260 0.07 ENST00000421054.7
GNRH1
gonadotropin releasing hormone 1
chr22_+_21665994 0.07 ENST00000680393.1
ENST00000679534.1
ENST00000679827.1
ENST00000681956.1
ENST00000681338.1
ENST00000680061.1
ENST00000679540.1
ENST00000679795.1
ENST00000335025.12
ENST00000398831.8
ENST00000679477.1
ENST00000626352.2
ENST00000458567.5
ENST00000680094.1
ENST00000680109.1
ENST00000406385.1
ENST00000680860.1
PPIL2
peptidylprolyl isomerase like 2
chr3_-_186570308 0.07 ENST00000446782.5
TBCCD1
TBCC domain containing 1
chr11_-_125111579 0.07 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
TMEM218
transmembrane protein 218
chr8_-_132675533 0.07 ENST00000620350.5
ENST00000518642.5
ENST00000250173.5
LRRC6
leucine rich repeat containing 6
chrX_+_47585212 0.07 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr11_+_117327829 0.07 ENST00000533153.5
ENST00000278935.8
ENST00000525416.5
CEP164
centrosomal protein 164
chr2_-_112433519 0.07 ENST00000496537.1
ENST00000330575.9
ENST00000302558.8
RGPD8
RANBP2 like and GRIP domain containing 8
chr2_-_206159410 0.06 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr1_+_84144260 0.06 ENST00000370685.7
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr7_+_144070313 0.06 ENST00000641441.1
OR2A25
olfactory receptor family 2 subfamily A member 25
chr5_+_143812161 0.06 ENST00000289448.4
HMHB1
histocompatibility minor HB-1
chr19_-_58353482 0.06 ENST00000263100.8
A1BG
alpha-1-B glycoprotein
chr10_-_95069489 0.06 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
CYP2C8
cytochrome P450 family 2 subfamily C member 8
chr5_+_119476530 0.06 ENST00000645099.1
ENST00000513628.5
HSD17B4
hydroxysteroid 17-beta dehydrogenase 4
chr11_-_18236795 0.06 ENST00000278222.7
SAA4
serum amyloid A4, constitutive
chr16_-_28363508 0.06 ENST00000532254.1
NPIPB6
nuclear pore complex interacting protein family member B6
chr2_+_161136901 0.06 ENST00000259075.6
ENST00000432002.5
TANK
TRAF family member associated NFKB activator
chr7_-_150302980 0.06 ENST00000252071.8
ACTR3C
actin related protein 3C
chr4_-_100517991 0.06 ENST00000511970.5
ENST00000502569.1
ENST00000305864.7
ENST00000296420.9
EMCN
endomucin
chr4_+_26343156 0.06 ENST00000680928.1
ENST00000681260.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_+_36084079 0.06 ENST00000207457.8
TEKT2
tektin 2
chr11_-_26572102 0.06 ENST00000455601.6
MUC15
mucin 15, cell surface associated
chr17_-_3298360 0.06 ENST00000323404.2
OR3A1
olfactory receptor family 3 subfamily A member 1
chr1_+_84181630 0.06 ENST00000610457.1
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr10_-_114144599 0.05 ENST00000428953.1
CCDC186
coiled-coil domain containing 186
chr3_-_142000353 0.05 ENST00000499676.5
TFDP2
transcription factor Dp-2
chr22_+_23856703 0.05 ENST00000345044.10
SLC2A11
solute carrier family 2 member 11
chr12_+_55549602 0.05 ENST00000641569.1
ENST00000641851.1
OR6C4
olfactory receptor family 6 subfamily C member 4
chr1_-_53940100 0.05 ENST00000371376.1
HSPB11
heat shock protein family B (small) member 11
chr2_-_201643448 0.05 ENST00000409883.7
TMEM237
transmembrane protein 237
chr11_-_26572254 0.05 ENST00000529533.6
MUC15
mucin 15, cell surface associated
chr12_+_26011713 0.05 ENST00000542004.5
RASSF8
Ras association domain family member 8
chr2_+_11542662 0.05 ENST00000389825.7
ENST00000381483.6
GREB1
growth regulating estrogen receptor binding 1
chr13_+_108269629 0.05 ENST00000430559.5
ENST00000375887.9
TNFSF13B
TNF superfamily member 13b
chr9_-_21202205 0.05 ENST00000239347.3
IFNA7
interferon alpha 7
chr6_+_27957241 0.05 ENST00000244623.1
OR2B6
olfactory receptor family 2 subfamily B member 6
chr3_-_131026726 0.05 ENST00000514044.5
ENST00000264992.8
ASTE1
asteroid homolog 1
chr4_-_88284747 0.05 ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr11_+_59511368 0.05 ENST00000641278.1
OR4D9
olfactory receptor family 4 subfamily D member 9
chr16_+_28637654 0.05 ENST00000529716.5
NPIPB8
nuclear pore complex interacting protein family member B8
chr9_-_21217311 0.05 ENST00000380216.1
IFNA16
interferon alpha 16
chr1_-_248277976 0.05 ENST00000641220.1
OR2T33
olfactory receptor family 2 subfamily T member 33
chr2_-_152175715 0.05 ENST00000263904.5
STAM2
signal transducing adaptor molecule 2
chr3_-_47513677 0.05 ENST00000296149.9
ELP6
elongator acetyltransferase complex subunit 6
chr11_-_26572130 0.05 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr1_+_197413827 0.05 ENST00000367397.1
ENST00000681519.1
CRB1
crumbs cell polarity complex component 1
chr22_-_40533808 0.04 ENST00000422851.1
ENST00000651694.1
ENST00000652095.2
MRTFA
myocardin related transcription factor A
chr4_+_94207596 0.04 ENST00000359052.8
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chrX_+_56729231 0.04 ENST00000637096.1
ENST00000374922.9
ENST00000423617.2
NBDY
negative regulator of P-body association
chr6_+_101398788 0.04 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr11_+_2384603 0.04 ENST00000527343.5
ENST00000464784.6
CD81
CD81 molecule
chr9_+_122371014 0.04 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr11_-_94973541 0.04 ENST00000279839.8
CWC15
CWC15 spliceosome associated protein homolog
chr4_-_112516176 0.04 ENST00000313341.4
NEUROG2
neurogenin 2
chr12_+_8157034 0.04 ENST00000396570.7
ZNF705A
zinc finger protein 705A
chr14_-_106470788 0.04 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr1_-_159714581 0.04 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
CRP
C-reactive protein
chr6_-_75363003 0.04 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr22_+_31754862 0.04 ENST00000382111.6
ENST00000645407.1
ENST00000646701.1
DEPDC5
ENSG00000285404.1
DEP domain containing 5, GATOR1 subcomplex subunit
novel protein, DEPDC5-YWHAH readthrough
chr17_-_41184895 0.04 ENST00000620667.1
ENST00000398472.2
KRTAP4-1
keratin associated protein 4-1
chr5_+_129748091 0.04 ENST00000564719.2
MINAR2
membrane integral NOTCH2 associated receptor 2
chr3_-_58537283 0.04 ENST00000459701.6
ACOX2
acyl-CoA oxidase 2
chr12_-_76083926 0.04 ENST00000551992.5
NAP1L1
nucleosome assembly protein 1 like 1
chr10_-_73655984 0.04 ENST00000394810.3
SYNPO2L
synaptopodin 2 like
chr19_+_14583076 0.04 ENST00000547437.5
ENST00000417570.6
CLEC17A
C-type lectin domain containing 17A
chr12_-_118359105 0.04 ENST00000541186.5
ENST00000539872.5
TAOK3
TAO kinase 3
chr15_-_78621272 0.04 ENST00000348639.7
CHRNA3
cholinergic receptor nicotinic alpha 3 subunit
chr17_+_29941605 0.04 ENST00000394835.7
EFCAB5
EF-hand calcium binding domain 5
chrX_+_91434829 0.04 ENST00000312600.4
PABPC5
poly(A) binding protein cytoplasmic 5
chr3_+_159839847 0.04 ENST00000445224.6
SCHIP1
schwannomin interacting protein 1
chr3_-_58537181 0.04 ENST00000302819.10
ACOX2
acyl-CoA oxidase 2
chr17_-_4263847 0.04 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr2_+_206159884 0.04 ENST00000392222.7
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr16_+_56961942 0.04 ENST00000200676.8
ENST00000566128.1
CETP
cholesteryl ester transfer protein
chr19_-_51417700 0.04 ENST00000529627.1
ENST00000439889.6
SIGLEC10
sialic acid binding Ig like lectin 10
chr9_-_14314132 0.04 ENST00000380953.6
NFIB
nuclear factor I B

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 1.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.5 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0070244 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101) negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 1.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 1.9 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.2 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)