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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ESR1

Z-value: 1.36

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ENSG00000091831.24 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg38_v1_chr6_+_151809105_151809139-0.186.7e-01Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_23949847 0.94 ENST00000588004.1
laminin subunit alpha 3
chr17_-_41521719 0.87 ENST00000393976.6
keratin 15
chr12_-_42483604 0.68 ENST00000640132.1
prickle planar cell polarity protein 1
chr4_-_10021490 0.65 ENST00000264784.8
solute carrier family 2 member 9
chr13_+_112894328 0.63 ENST00000375608.7
MCF.2 cell line derived transforming sequence like
chr5_-_1886938 0.54 ENST00000613726.4
iroquois homeobox 4
chr1_+_186828941 0.53 ENST00000367466.4
phospholipase A2 group IVA
chr4_-_15938740 0.53 ENST00000382333.2
fibroblast growth factor binding protein 1
chr5_-_140346596 0.52 ENST00000230990.7
heparin binding EGF like growth factor
chr13_-_20230970 0.51 ENST00000644667.1
ENST00000646108.1
gap junction protein beta 6
chr16_+_75222609 0.51 ENST00000495583.1
chymotrypsinogen B1
chr14_-_94390650 0.49 ENST00000449399.7
ENST00000404814.8
serpin family A member 1
chr19_+_4279285 0.48 ENST00000599689.1
Src homology 2 domain containing transforming protein D
chr3_-_111595339 0.43 ENST00000317012.5
zinc finger BED-type containing 2
chr12_-_14567714 0.42 ENST00000240617.10
phospholipase B domain containing 1
chr3_+_148697784 0.42 ENST00000497524.5
ENST00000418473.7
ENST00000349243.8
ENST00000404754.2
angiotensin II receptor type 1
chr4_-_88158605 0.40 ENST00000237612.8
ATP binding cassette subfamily G member 2 (Junior blood group)
chr5_-_16508951 0.40 ENST00000682628.1
reticulophagy regulator 1
chr11_-_47248789 0.38 ENST00000529444.7
ENST00000672787.1
ENST00000672073.1
ENST00000672636.2
ENST00000527256.7
acid phosphatase 2, lysosomal
chr6_+_32154131 0.38 ENST00000375143.6
ENST00000324816.11
ENST00000424499.1
palmitoyl-protein thioesterase 2
chr14_-_94390667 0.37 ENST00000557492.5
ENST00000355814.8
ENST00000437397.5
ENST00000448921.5
ENST00000393088.8
serpin family A member 1
chr21_-_44928711 0.36 ENST00000517563.5
integrin subunit beta 2
chr14_-_94390614 0.36 ENST00000553327.5
ENST00000556955.5
ENST00000557118.5
ENST00000440909.5
serpin family A member 1
chr11_-_47248835 0.36 ENST00000673604.1
ENST00000256997.9
acid phosphatase 2, lysosomal
chr11_+_32829903 0.36 ENST00000257836.4
proline rich and Gla domain 4
chr5_-_16508990 0.36 ENST00000399793.6
reticulophagy regulator 1
chr6_+_32154010 0.35 ENST00000375137.6
palmitoyl-protein thioesterase 2
chr3_+_119146184 0.34 ENST00000460150.1
testis expressed 55
chr16_+_29679132 0.33 ENST00000395384.9
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr9_+_127716073 0.32 ENST00000373289.4
tetratricopeptide repeat domain 16
chr4_-_80073057 0.31 ENST00000681710.1
ANTXR cell adhesion molecule 2
chr17_+_57096572 0.30 ENST00000539273.5
A-kinase anchoring protein 1
chr12_-_94650506 0.30 ENST00000261226.9
transmembrane and coiled-coil domain family 3
chr8_-_143953845 0.30 ENST00000354958.6
plectin
chr1_+_161707222 0.30 ENST00000236938.12
Fc receptor like A
chr6_+_32153441 0.29 ENST00000414204.5
ENST00000361568.6
ENST00000395523.5
palmitoyl-protein thioesterase 2
chr11_-_60952559 0.29 ENST00000538739.2
solute carrier family 15 member 3
chr12_+_65169546 0.29 ENST00000308330.3
LEM domain containing 3
chr21_-_45542414 0.29 ENST00000311124.9
solute carrier family 19 member 1
chr14_+_103100328 0.29 ENST00000559116.1
exocyst complex component 3 like 4
chr11_+_94543894 0.27 ENST00000358752.4
fucosyltransferase 4
chr14_+_85533167 0.27 ENST00000682132.1
fibronectin leucine rich transmembrane protein 2
chr1_-_153460644 0.27 ENST00000368723.4
S100 calcium binding protein A7
chr11_-_60952067 0.27 ENST00000681275.1
solute carrier family 15 member 3
chr1_-_209652329 0.26 ENST00000367030.7
ENST00000356082.9
laminin subunit beta 3
chr20_-_51768327 0.26 ENST00000311637.9
ENST00000338821.6
ATPase phospholipid transporting 9A (putative)
chr1_+_161707244 0.26 ENST00000349527.8
ENST00000294796.8
ENST00000309691.10
ENST00000367953.7
ENST00000367950.2
Fc receptor like A
chr22_+_22880706 0.26 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr5_-_140633167 0.26 ENST00000302014.11
CD14 molecule
chrX_+_38561530 0.25 ENST00000378482.7
ENST00000286824.6
tetraspanin 7
chr11_+_60924452 0.25 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
transmembrane protein 132A
chr2_+_119223815 0.25 ENST00000393106.6
ENST00000393110.7
ENST00000409811.5
ENST00000393107.2
STEAP3 metalloreductase
chr4_-_80073465 0.25 ENST00000404191.5
ANTXR cell adhesion molecule 2
chr11_-_1036706 0.25 ENST00000421673.7
mucin 6, oligomeric mucus/gel-forming
chr1_-_28176665 0.25 ENST00000373857.8
platelet activating factor receptor
chr19_-_14979676 0.25 ENST00000598504.5
ENST00000597262.1
solute carrier family 1 member 6
chr8_+_104223320 0.24 ENST00000339750.3
regulating synaptic membrane exocytosis 2
chr1_-_227947924 0.24 ENST00000272164.6
Wnt family member 9A
chr1_+_153031195 0.24 ENST00000307098.5
small proline rich protein 1B
chr10_-_102120246 0.24 ENST00000425280.2
LIM domain binding 1
chr12_-_42483958 0.24 ENST00000548696.6
ENST00000552240.6
prickle planar cell polarity protein 1
chr8_-_109644766 0.24 ENST00000533065.5
ENST00000276646.14
syntabulin
chr8_-_143609547 0.24 ENST00000433751.5
ENST00000495276.6
ENST00000220966.10
pyrroline-5-carboxylate reductase 3
chr21_-_45542465 0.24 ENST00000380010.8
solute carrier family 19 member 1
chr2_-_74552616 0.24 ENST00000409249.5
lysyl oxidase like 3
chr17_+_7420315 0.23 ENST00000323675.4
spermatid maturation 1
chr4_-_80073170 0.23 ENST00000403729.7
ANTXR cell adhesion molecule 2
chr15_+_32718476 0.23 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr19_-_15934521 0.23 ENST00000402119.9
cytochrome P450 family 4 subfamily F member 11
chr19_-_15934853 0.23 ENST00000620614.4
ENST00000248041.12
cytochrome P450 family 4 subfamily F member 11
chr11_+_66843413 0.23 ENST00000524506.5
ENST00000309657.8
Ras converting CAAX endopeptidase 1
chr11_+_118077067 0.22 ENST00000522307.5
ENST00000523251.5
ENST00000437212.8
ENST00000522824.5
ENST00000522151.5
transmembrane serine protease 4
chr14_-_106762576 0.22 ENST00000624687.1
immunoglobulin heavy variable 1-69D
chr17_-_43125450 0.22 ENST00000494123.5
ENST00000468300.5
ENST00000471181.7
ENST00000652672.1
BRCA1 DNA repair associated
chr9_-_121370275 0.22 ENST00000538954.5
stomatin
chr16_+_66880503 0.22 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr4_-_100190458 0.22 ENST00000273990.6
DNA damage inducible transcript 4 like
chr2_-_74529670 0.22 ENST00000377526.4
AUP1 lipid droplet regulating VLDL assembly factor
chr11_+_20387681 0.22 ENST00000437750.2
ENST00000331079.11
protein arginine methyltransferase 3
chr19_-_17264732 0.22 ENST00000252597.8
USH1 protein network component harmonin binding protein 1
chr11_-_118264282 0.22 ENST00000278937.7
myelin protein zero like 2
chr11_-_8682619 0.22 ENST00000646038.2
tripartite motif containing 66
chr15_+_90249528 0.21 ENST00000438251.3
tubulin tyrosine ligase like 13, pseudogene
chr1_+_220786853 0.21 ENST00000366910.10
mitochondrial amidoxime reducing component 1
chr1_+_1282109 0.21 ENST00000325425.12
sodium channel epithelial 1 subunit delta
chr19_-_43082692 0.21 ENST00000406487.6
pregnancy specific beta-1-glycoprotein 2
chr10_+_79706328 0.21 ENST00000342531.2
NUT family member 2B
chr11_-_7673485 0.21 ENST00000299498.11
cytochrome b5 reductase 2
chr9_-_34637800 0.21 ENST00000680730.1
ENST00000477726.1
sigma non-opioid intracellular receptor 1
chr1_+_6450374 0.21 ENST00000475479.2
espin
chr11_+_118077009 0.21 ENST00000616579.4
ENST00000534111.5
transmembrane serine protease 4
chr1_+_209675404 0.21 ENST00000367029.5
G0/G1 switch 2
chr9_-_34637719 0.20 ENST00000378892.5
ENST00000680277.1
ENST00000277010.9
ENST00000679597.1
ENST00000680244.1
sigma non-opioid intracellular receptor 1
chr11_-_119346655 0.20 ENST00000360167.4
membrane frizzled-related protein
chr11_-_60952134 0.20 ENST00000679573.1
ENST00000681882.1
ENST00000681951.1
ENST00000227880.8
solute carrier family 15 member 3
chr19_-_6720641 0.20 ENST00000245907.11
complement C3
chr5_+_149730260 0.20 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARG coactivator 1 beta
chr19_+_17281863 0.20 ENST00000652132.1
ENST00000404085.7
ENST00000598347.2
ankyrin repeat and LEM domain containing 1
chr15_+_88639009 0.20 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr4_+_2418932 0.19 ENST00000635017.1
cilia and flagella associated protein 99
chr3_-_94062906 0.19 ENST00000314636.3
ENST00000394221.3
dihydrofolate reductase 2
chr11_+_64241053 0.19 ENST00000309366.9
ENST00000449942.6
ENST00000652762.2
FKBP prolyl isomerase 2
novel protein
chr13_+_112969179 0.19 ENST00000535094.7
MCF.2 cell line derived transforming sequence like
chr1_-_246566238 0.19 ENST00000366514.5
transcription factor B2, mitochondrial
chr2_-_97995916 0.19 ENST00000186436.10
transmembrane protein 131
chr8_+_141128581 0.19 ENST00000519811.6
DENN domain containing 3
chr1_+_32362537 0.19 ENST00000373534.4
testis specific serine kinase 3
chr21_-_44873671 0.19 ENST00000330938.8
ENST00000397887.7
PTTG1 interacting protein
chr7_-_122699108 0.19 ENST00000340112.3
ring finger protein 133
chr22_+_22409755 0.19 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr11_-_118264445 0.18 ENST00000438295.2
myelin protein zero like 2
chr19_-_51367977 0.18 ENST00000593841.1
claudin domain containing 2
chr19_+_49335396 0.18 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr22_+_37906275 0.18 ENST00000215957.10
ENST00000445494.6
ENST00000680578.1
ENST00000424008.2
MICAL like 1
chr8_+_141128612 0.18 ENST00000518347.5
ENST00000262585.6
ENST00000520986.5
ENST00000523058.5
ENST00000518668.5
DENN domain containing 3
chr9_-_136746006 0.18 ENST00000476567.1
lipocalin 6
chr9_+_136952896 0.18 ENST00000371632.7
lipocalin 12
chr9_+_136952256 0.18 ENST00000371633.8
lipocalin 12
chr2_-_70995336 0.18 ENST00000606025.5
novel protein
chr11_+_844406 0.18 ENST00000397404.5
tetraspanin 4
chr16_+_285680 0.18 ENST00000435833.1
protein disulfide isomerase family A member 2
chr10_-_102120318 0.18 ENST00000673968.1
LIM domain binding 1
chr3_+_50273119 0.18 ENST00000456560.6
ENST00000418576.3
semaphorin 3B
chr2_+_230225718 0.18 ENST00000420434.7
ENST00000392045.8
ENST00000417495.7
ENST00000343805.10
SP140 nuclear body protein
chr8_-_11466740 0.18 ENST00000284486.9
family with sequence similarity 167 member A
chr12_-_51026345 0.17 ENST00000547732.5
ENST00000644495.1
ENST00000262052.9
ENST00000546488.5
ENST00000550714.5
ENST00000548193.5
ENST00000547579.5
ENST00000546743.5
solute carrier family 11 member 2
chr10_-_107164692 0.17 ENST00000263054.11
sortilin related VPS10 domain containing receptor 1
chr3_-_48563774 0.17 ENST00000273610.4
urocortin 2
chr1_+_196774813 0.17 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr15_+_89575492 0.17 ENST00000560985.5
TOPBP1 interacting checkpoint and replication regulator
chr11_+_18132565 0.17 ENST00000621697.2
MAS related GPR family member X3
chr19_+_50649445 0.17 ENST00000425202.6
chromosome 19 open reading frame 81
chr13_-_113364085 0.17 ENST00000375431.9
growth hormone regulated TBC protein 1
chr19_+_49691103 0.17 ENST00000323446.9
ENST00000392518.8
ENST00000598293.6
ENST00000598396.5
ENST00000405931.6
ENST00000602019.5
carnitine palmitoyltransferase 1C
chr15_+_51681483 0.17 ENST00000542355.6
ENST00000220478.8
ENST00000558709.1
secretogranin III
chr15_-_68229658 0.17 ENST00000565471.6
ENST00000637494.1
ENST00000636314.1
ENST00000637667.1
ENST00000564752.1
ENST00000566347.5
ENST00000249806.11
ENST00000562767.2
CLN6 transmembrane ER protein
novel protein
chr8_+_104223344 0.17 ENST00000523362.5
regulating synaptic membrane exocytosis 2
chr6_+_44223770 0.17 ENST00000652453.1
ENST00000393841.6
ENST00000371724.6
ENST00000642777.1
ENST00000645692.1
solute carrier family 29 member 1 (Augustine blood group)
chr19_-_48673017 0.17 ENST00000270235.11
ENST00000596844.5
netrin 5
chr12_-_14696571 0.16 ENST00000261170.5
guanylate cyclase 2C
chr10_+_99659430 0.16 ENST00000370489.5
ectonucleoside triphosphate diphosphohydrolase 7
chr21_-_39445719 0.16 ENST00000438404.5
ENST00000358268.6
ENST00000411566.5
ENST00000451131.1
ENST00000418018.5
ENST00000415863.5
ENST00000426783.5
ENST00000485895.6
ENST00000288350.8
ENST00000448288.6
ENST00000456017.5
ENST00000434281.5
lebercilin LCA5 like
chr17_-_2711633 0.16 ENST00000435359.5
clustered mitochondria homolog
chr3_-_50303565 0.16 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
hyaluronidase 1
chr7_+_142492121 0.16 ENST00000390374.3
T cell receptor beta variable 7-6
chr21_+_33070133 0.16 ENST00000382348.2
oligodendrocyte transcription factor 1
chr15_+_50182215 0.16 ENST00000380902.8
solute carrier family 27 member 2
chr19_+_17281645 0.16 ENST00000394458.7
ENST00000594072.6
ankyrin repeat and LEM domain containing 1
chr15_-_41230697 0.16 ENST00000314992.9
ENST00000558396.1
ENST00000458580.7
exonuclease 3'-5' domain containing 1
chr6_-_44257279 0.16 ENST00000619636.4
solute carrier family 35 member B2
chr11_-_86672114 0.16 ENST00000393324.7
malic enzyme 3
chr22_+_22357739 0.16 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr10_+_70478761 0.16 ENST00000263563.7
phosphatase domain containing paladin 1
chr19_+_4279247 0.16 ENST00000543264.7
Src homology 2 domain containing transforming protein D
chr1_+_206897435 0.16 ENST00000391929.7
ENST00000294984.7
ENST00000611909.4
ENST00000367093.3
interleukin 24
chr19_+_44846175 0.16 ENST00000252485.8
ENST00000252483.10
nectin cell adhesion molecule 2
chr12_-_47725483 0.16 ENST00000422538.8
endonuclease, poly(U) specific
chr18_-_7117786 0.16 ENST00000389658.4
laminin subunit alpha 1
chr9_-_124500986 0.15 ENST00000373587.3
nuclear receptor subfamily 5 group A member 1
chr13_+_112968496 0.15 ENST00000397030.5
MCF.2 cell line derived transforming sequence like
chr17_-_19716573 0.15 ENST00000433844.4
solute carrier family 47 member 2
chr1_+_207752046 0.15 ENST00000367042.6
ENST00000322875.8
ENST00000322918.9
ENST00000354848.5
ENST00000357714.5
ENST00000358170.6
ENST00000367041.5
ENST00000367047.5
ENST00000360212.6
ENST00000480003.5
CD46 molecule
chr5_+_58583068 0.15 ENST00000282878.6
RAB3C, member RAS oncogene family
chr20_+_44910045 0.15 ENST00000255136.8
ENST00000217073.7
poly(A) binding protein cytoplasmic 1 like
chr16_+_69951180 0.15 ENST00000288040.10
ENST00000449317.6
C-type lectin domain family 18 member A
chr17_-_3433841 0.15 ENST00000248384.1
olfactory receptor family 1 subfamily E member 2
chr3_+_63911929 0.15 ENST00000487717.5
ataxin 7
chr11_+_72114840 0.15 ENST00000622388.4
folate receptor gamma
chr15_+_50182188 0.15 ENST00000267842.10
solute carrier family 27 member 2
chr17_+_56834081 0.15 ENST00000572810.1
ENST00000284061.8
diacylglycerol kinase epsilon
chr3_-_10708007 0.15 ENST00000646379.1
ATPase plasma membrane Ca2+ transporting 2
chr9_-_120926752 0.15 ENST00000373887.8
TNF receptor associated factor 1
chr1_+_34166883 0.15 ENST00000373374.7
chromosome 1 open reading frame 94
chr17_-_19716604 0.15 ENST00000325411.9
ENST00000350657.9
solute carrier family 47 member 2
chr6_-_41039202 0.15 ENST00000244565.8
unc-5 family C-terminal like
chr16_+_1772802 0.15 ENST00000568449.7
essential meiotic structure-specific endonuclease subunit 2
chr6_-_2971235 0.14 ENST00000644777.1
serpin family B member 6
chr17_-_28726186 0.14 ENST00000292090.8
TLC domain containing 1
chr15_+_81134257 0.14 ENST00000286732.5
cilia and flagella associated protein 161
chr2_+_11539833 0.14 ENST00000263834.9
growth regulating estrogen receptor binding 1
chr12_+_113221429 0.14 ENST00000551096.5
ENST00000551099.5
ENST00000552897.5
ENST00000550785.5
ENST00000549279.1
ENST00000335509.11
two pore segment channel 1
chrX_-_72875974 0.14 ENST00000595412.5
DMRT like family C1
chr17_+_32350132 0.14 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
zinc finger protein 207
chr16_-_74700845 0.14 ENST00000308807.12
ENST00000573267.1
mixed lineage kinase domain like pseudokinase
chr11_+_1410443 0.14 ENST00000528710.5
BR serine/threonine kinase 2
chr2_-_70994809 0.14 ENST00000272438.9
testis expressed 261
chr1_+_220528112 0.14 ENST00000366917.6
ENST00000402574.5
ENST00000611084.4
ENST00000366918.8
microtubule affinity regulating kinase 1
chr8_+_62248591 0.14 ENST00000519049.6
sodium/potassium transporting ATPase interacting 3
chr6_+_143843316 0.14 ENST00000367576.6
LTV1 ribosome biogenesis factor
chr17_+_42854078 0.14 ENST00000591562.1
ENST00000588033.1
amine oxidase copper containing 3
chr11_+_62419025 0.14 ENST00000278282.3
secretoglobin family 1A member 1
chr1_+_154429315 0.14 ENST00000476006.5
interleukin 6 receptor
chr19_-_51009586 0.14 ENST00000594211.2
kallikrein related peptidase 9
chr16_-_74700786 0.14 ENST00000306247.11
ENST00000575686.1
mixed lineage kinase domain like pseudokinase
chr1_+_19664859 0.13 ENST00000289753.2
5-hydroxytryptamine receptor 6
chr2_-_88992903 0.13 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr1_+_179882688 0.13 ENST00000435319.8
torsin 1A interacting protein 1
chr12_+_122774566 0.13 ENST00000253079.11
coiled-coil domain containing 62
chr22_+_22380766 0.13 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr1_-_223665685 0.13 ENST00000366872.10
calpain 8

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 0.5 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 0.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.4 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.4 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.5 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.5 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.7 GO:0061709 reticulophagy(GO:0061709)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 1.0 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.2 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 0.5 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.2 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.1 0.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.9 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.2 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.0 0.3 GO:0072526 quinolinate metabolic process(GO:0046874) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.2 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.1 GO:0032761 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.0 0.1 GO:0018963 phthalate metabolic process(GO:0018963)
0.0 0.2 GO:0007538 primary sex determination(GO:0007538)
0.0 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0071464 cellular response to hydrostatic pressure(GO:0071464)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.1 GO:0071317 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.2 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:1902617 response to fluoride(GO:1902617)
0.0 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.2 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.1 GO:1903611 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.3 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:1900450 negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782)
0.0 0.1 GO:0097676 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.0 0.2 GO:1903416 response to glycoside(GO:1903416)
0.0 0.2 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.0 GO:0070894 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.1 GO:1905224 clathrin coat disassembly(GO:0072318) clathrin-coated pit assembly(GO:1905224)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.4 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0031022 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.4 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0071920 cleavage body(GO:0071920)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 1.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.1 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.8 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.5 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.4 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.3 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.6 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004341 gluconolactonase activity(GO:0004341)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.0 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.0 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling