Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSG00000075426.12 | FOS like 2, AP-1 transcription factor subunit | |
ENSG00000173473.11 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
FOSL2 | hg38_v1_chr2_+_28395511_28395743 | -0.36 | 3.9e-01 | Click! |
SMARCC1 | hg38_v1_chr3_-_47781837_47781908 | -0.04 | 9.2e-01 | Click! |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr18_+_23873000 Show fit | 6.29 |
ENST00000269217.11
ENST00000587184.5 |
laminin subunit alpha 3 |
|
chr19_-_35513641 Show fit | 2.33 |
ENST00000339686.8
ENST00000447113.6 |
dermokine |
|
chr17_-_41612757 Show fit | 2.29 |
ENST00000301653.9
ENST00000593067.1 |
keratin 16 |
|
chr19_-_35501878 Show fit | 2.29 |
ENST00000593342.5
ENST00000601650.1 ENST00000408915.6 |
dermokine |
|
chr20_+_46008900 Show fit | 1.89 |
ENST00000372330.3
|
matrix metallopeptidase 9 |
|
chr18_+_63775369 Show fit | 1.77 |
ENST00000540675.5
|
serpin family B member 7 |
|
chr19_-_51020154 Show fit | 1.75 |
ENST00000391805.5
ENST00000599077.1 |
kallikrein related peptidase 10 |
|
chr18_+_63775395 Show fit | 1.74 |
ENST00000398019.7
|
serpin family B member 7 |
|
chr2_+_102001966 Show fit | 1.69 |
ENST00000457817.5
|
interleukin 1 receptor type 2 |
|
chr19_-_51020019 Show fit | 1.66 |
ENST00000309958.7
|
kallikrein related peptidase 10 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 8.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
1.2 | 4.6 | GO:1903575 | cornified envelope assembly(GO:1903575) |
0.1 | 4.5 | GO:0061436 | establishment of skin barrier(GO:0061436) |
0.9 | 4.3 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
0.3 | 2.6 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
0.0 | 2.5 | GO:0044380 | protein localization to cytoskeleton(GO:0044380) |
0.5 | 1.8 | GO:0002159 | desmosome assembly(GO:0002159) |
0.4 | 1.7 | GO:0050712 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
0.0 | 1.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.1 | 1.5 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 6.8 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.1 | 3.5 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 2.6 | GO:0001650 | fibrillar center(GO:0001650) |
0.1 | 2.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 1.8 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 1.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.2 | 1.4 | GO:0097451 | glial limiting end-foot(GO:0097451) |
0.1 | 1.3 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.1 | 1.3 | GO:0031932 | TORC2 complex(GO:0031932) |
0.1 | 1.1 | GO:0005827 | polar microtubule(GO:0005827) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 5.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 4.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 2.7 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 2.7 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.1 | 2.0 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 1.8 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.3 | 1.7 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
0.1 | 1.4 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 1.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 1.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 8.6 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 4.2 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
0.0 | 2.9 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 2.1 | PID IL1 PATHWAY | IL1-mediated signaling events |
0.0 | 1.6 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 1.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 1.3 | PID MTOR 4PATHWAY | mTOR signaling pathway |
0.0 | 0.7 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.0 | 0.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.0 | 0.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 9.9 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
0.1 | 3.1 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
0.1 | 2.9 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 2.9 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 1.3 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.1 | 1.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 1.0 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
0.0 | 0.9 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 0.7 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
0.0 | 0.7 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |