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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 1.28

Motif logo

Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol Gene ID Gene Info
ENSG00000251493.5 forkhead box D1
ENSG00000150907.10 forkhead box O1
ENSG00000204060.7 forkhead box O6
ENSG00000176165.12 forkhead box G1
ENSG00000114861.23 forkhead box P1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXP1hg38_v1_chr3_-_71130892_71130959-0.705.2e-02Click!
FOXO1hg38_v1_chr13_-_40666600_406666500.639.7e-02Click!
FOXD1hg38_v1_chr5_-_73448769_73448784-0.531.8e-01Click!
FOXG1hg38_v1_chr14_+_28766755_28766802-0.423.0e-01Click!

Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_110225955 2.16 ENST00000239007.11
MAX interactor 1, dimerization protein
chr8_+_31639755 1.34 ENST00000520407.5
neuregulin 1
chr11_-_72793636 1.30 ENST00000538536.5
ENST00000543304.5
ENST00000540587.1
StAR related lipid transfer domain containing 10
chr6_+_89081787 1.02 ENST00000354922.3
proline rich nuclear receptor coactivator 1
chr12_-_52949818 1.02 ENST00000546897.5
ENST00000552551.5
keratin 8
chr16_-_30096170 0.95 ENST00000566134.5
ENST00000565110.5
ENST00000398841.6
ENST00000398838.8
yippee like 3
chr2_+_162318884 0.95 ENST00000446271.5
ENST00000429691.6
grancalcin
chr6_+_125219804 0.90 ENST00000524679.1
TPD52 like 1
chr7_+_107168961 0.87 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HMG-box transcription factor 1
chr10_-_121596117 0.86 ENST00000351936.11
fibroblast growth factor receptor 2
chr7_+_30134956 0.83 ENST00000324453.13
ENST00000409688.1
maturin, neural progenitor differentiation regulator homolog
chr17_+_41237998 0.82 ENST00000254072.7
keratin associated protein 9-8
chr13_-_40666600 0.81 ENST00000379561.6
forkhead box O1
chr8_+_119067239 0.77 ENST00000332843.3
collectin subfamily member 10
chrX_-_31178220 0.76 ENST00000681026.1
dystrophin
chrX_-_31178149 0.75 ENST00000679437.1
dystrophin
chr17_+_60677822 0.75 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr10_+_23439060 0.74 ENST00000376495.5
OTU deubiquitinase 1
chr1_+_226940279 0.74 ENST00000366778.5
ENST00000366777.4
coenzyme Q8A
chr3_-_18424533 0.73 ENST00000417717.6
SATB homeobox 1
chr18_-_55589795 0.71 ENST00000568740.5
ENST00000629387.2
transcription factor 4
chr11_+_10455292 0.71 ENST00000396553.6
adenosine monophosphate deaminase 3
chr11_-_72794032 0.70 ENST00000334805.11
StAR related lipid transfer domain containing 10
chrX_+_136169664 0.70 ENST00000456445.5
four and a half LIM domains 1
chr18_+_68798065 0.68 ENST00000360242.9
coiled-coil domain containing 102B
chr18_-_55589836 0.67 ENST00000537578.5
ENST00000564403.6
transcription factor 4
chr19_-_47231191 0.65 ENST00000439096.3
BCL2 binding component 3
chr2_+_86720282 0.65 ENST00000283632.5
required for meiotic nuclear division 5 homolog A
chr6_-_30075767 0.64 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr18_-_55589770 0.64 ENST00000565018.6
ENST00000636400.2
transcription factor 4
chr7_-_112939773 0.63 ENST00000297145.9
base methyltransferase of 25S rRNA 2 homolog
chrX_+_136169624 0.62 ENST00000394153.6
four and a half LIM domains 1
chr5_+_79236092 0.62 ENST00000396137.5
junction mediating and regulatory protein, p53 cofactor
chr19_+_18386150 0.60 ENST00000252809.3
growth differentiation factor 15
chr15_-_30991415 0.60 ENST00000563714.5
myotubularin related protein 10
chr6_+_36676489 0.59 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr8_-_80080816 0.59 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr17_+_59331633 0.57 ENST00000312655.9
yippee like 2
chr8_+_98944403 0.56 ENST00000457907.3
ENST00000523368.5
ENST00000297565.8
ENST00000435298.6
odd-skipped related transciption factor 2
chr11_-_72793592 0.55 ENST00000536377.5
ENST00000359373.9
StAR related lipid transfer domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr6_-_32154326 0.55 ENST00000475826.1
ENST00000485392.5
ENST00000494332.5
ENST00000498575.1
ENST00000428778.5
novel transcript
novel protein
chrX_+_136169891 0.54 ENST00000449474.5
four and a half LIM domains 1
chr20_-_1329131 0.54 ENST00000360779.4
syndecan binding protein 2
chr11_-_34513785 0.53 ENST00000257832.7
ENST00000429939.6
E74 like ETS transcription factor 5
chr17_-_44324770 0.53 ENST00000592857.5
ENST00000586016.5
ENST00000590194.5
ENST00000588049.5
ENST00000586633.5
ENST00000377095.10
ENST00000537904.6
ENST00000585636.5
ENST00000585523.1
ENST00000225308.12
solute carrier family 25 member 39
chrX_+_136169833 0.53 ENST00000628032.2
four and a half LIM domains 1
chr5_-_36301883 0.52 ENST00000502994.5
ENST00000515759.5
ENST00000296604.8
RAN binding protein 3 like
chr14_+_24114627 0.51 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr3_-_114758940 0.50 ENST00000464560.5
zinc finger and BTB domain containing 20
chr14_+_24115299 0.50 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr19_+_12791470 0.49 ENST00000302754.6
JunB proto-oncogene, AP-1 transcription factor subunit
chr2_+_17541157 0.49 ENST00000406397.1
visinin like 1
chr17_-_41786688 0.48 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
junction plakoglobin
chr18_-_55403682 0.48 ENST00000564228.5
ENST00000630828.2
transcription factor 4
chr19_+_45340774 0.48 ENST00000589837.5
kinesin light chain 3
chr3_-_190449782 0.48 ENST00000354905.3
transmembrane protein 207
chr7_-_140640776 0.47 ENST00000275884.10
ENST00000475837.1
ENST00000496613.6
DENN domain containing 2A
chr2_-_71227055 0.47 ENST00000244221.9
poly(A) binding protein interacting protein 2B
chr1_+_24319342 0.46 ENST00000361548.9
grainyhead like transcription factor 3
chr20_+_59604527 0.46 ENST00000371015.6
phosphatase and actin regulator 3
chr2_-_68871382 0.46 ENST00000295379.2
bone morphogenetic protein 10
chr11_-_111910830 0.46 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr19_+_1205761 0.46 ENST00000326873.12
ENST00000586243.5
serine/threonine kinase 11
chr11_-_111910888 0.45 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr2_+_17540670 0.45 ENST00000451533.5
ENST00000295156.9
visinin like 1
chr3_+_50155024 0.45 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr18_-_55635948 0.45 ENST00000565124.4
ENST00000398339.5
transcription factor 4
chr4_-_140154176 0.44 ENST00000509479.6
mastermind like transcriptional coactivator 3
chr6_+_83853576 0.44 ENST00000369687.2
ripply transcriptional repressor 2
chr5_+_122129533 0.44 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr11_-_111910790 0.43 ENST00000533280.6
crystallin alpha B
chr19_+_45340736 0.43 ENST00000391946.7
kinesin light chain 3
chr19_+_45340760 0.43 ENST00000585434.5
kinesin light chain 3
chr22_-_31292445 0.43 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr1_+_152514474 0.42 ENST00000368790.4
cysteine rich C-terminal 1
chr1_+_24319511 0.41 ENST00000356046.6
grainyhead like transcription factor 3
chr10_-_44978789 0.41 ENST00000448778.1
ENST00000298295.4
DEPP1 autophagy regulator
chr2_-_73779968 0.41 ENST00000452812.1
ENST00000443070.5
ENST00000272444.7
dual specificity phosphatase 11
chr8_+_49911801 0.41 ENST00000643809.1
syntrophin gamma 1
chr6_+_138773747 0.40 ENST00000617445.5
coiled-coil domain containing 28A
chr10_+_80413817 0.40 ENST00000372187.9
peroxiredoxin like 2A
chr1_+_87331668 0.39 ENST00000370542.1
LIM domain only 4
chr11_-_34513750 0.38 ENST00000532417.1
E74 like ETS transcription factor 5
chr7_+_129368123 0.38 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr8_-_133297092 0.38 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr18_+_23949847 0.38 ENST00000588004.1
laminin subunit alpha 3
chr6_-_136526177 0.38 ENST00000617204.4
microtubule associated protein 7
chr9_-_86282511 0.37 ENST00000375991.9
ENST00000326094.4
iron-sulfur cluster assembly 1
chr13_-_85799400 0.37 ENST00000647374.2
SLIT and NTRK like family member 6
chr17_-_28335421 0.36 ENST00000578122.5
ENST00000579419.5
ENST00000585313.5
ENST00000578985.5
ENST00000577498.1
ENST00000585089.5
ENST00000357896.7
ENST00000395418.8
ENST00000588477.5
intraflagellar transport 20
chr9_-_86282061 0.36 ENST00000311534.6
iron-sulfur cluster assembly 1
chrX_+_71095838 0.36 ENST00000374259.8
forkhead box O4
chr1_-_1421248 0.36 ENST00000442470.1
ENST00000537107.6
ankyrin repeat domain 65
chr17_+_28335571 0.35 ENST00000544907.6
TNF alpha induced protein 1
chr6_-_136526472 0.35 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr7_-_151248668 0.35 ENST00000262188.13
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_-_120128831 0.35 ENST00000529044.5
tripartite motif containing 29
chr10_+_97319250 0.35 ENST00000371021.5
FRAT regulator of WNT signaling pathway 1
chr8_-_126558461 0.34 ENST00000304916.4
LRAT domain containing 2
chr1_-_1421302 0.34 ENST00000520296.5
ankyrin repeat domain 65
chr1_-_201127184 0.34 ENST00000449188.3
achaete-scute family bHLH transcription factor 5
chr17_+_28335718 0.34 ENST00000226225.7
TNF alpha induced protein 1
chr3_-_114759115 0.34 ENST00000471418.5
zinc finger and BTB domain containing 20
chr22_-_37109409 0.34 ENST00000406725.6
transmembrane serine protease 6
chr18_+_58862904 0.33 ENST00000591083.5
zinc finger protein 532
chr17_+_59220446 0.33 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
glycerophosphodiester phosphodiesterase domain containing 1
chr9_-_91361889 0.33 ENST00000303617.5
ENST00000375731.9
AU RNA binding methylglutaconyl-CoA hydratase
chr14_-_21025490 0.33 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr5_-_142686079 0.32 ENST00000337706.7
fibroblast growth factor 1
chr2_-_159616442 0.32 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
bromodomain adjacent to zinc finger domain 2B
chr20_+_45407207 0.32 ENST00000372712.6
dysbindin domain containing 2
chr4_-_151227881 0.32 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr4_-_73620391 0.31 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr9_-_3525968 0.30 ENST00000382004.7
ENST00000617270.5
ENST00000449190.5
regulatory factor X3
chr10_+_102644990 0.30 ENST00000645961.1
tripartite motif containing 8
chr12_-_31326111 0.30 ENST00000539409.5
SIN3-HDAC complex associated factor
chr6_-_136525961 0.30 ENST00000438100.6
microtubule associated protein 7
chr4_+_85475131 0.30 ENST00000395184.6
Rho GTPase activating protein 24
chr9_-_95516959 0.29 ENST00000437951.6
ENST00000430669.6
ENST00000468211.6
patched 1
chr14_+_24398986 0.29 ENST00000382554.4
NYN domain and retroviral integrase containing
chr1_-_202958258 0.29 ENST00000367254.7
ENST00000426229.1
ENST00000340990.10
adiponectin receptor 1
chr10_-_97334698 0.29 ENST00000371019.4
FRAT regulator of WNT signaling pathway 2
chr1_+_33256479 0.29 ENST00000539719.6
ENST00000483388.5
zinc finger protein 362
chr2_-_25982471 0.28 ENST00000264712.8
kinesin family member 3C
chr1_-_45491150 0.28 ENST00000372086.4
testis associated actin remodelling kinase 2
chr2_+_27442421 0.28 ENST00000407293.5
keratinocyte associated protein 3
chr7_-_27095972 0.28 ENST00000355633.5
ENST00000643460.2
homeobox A1
chr6_+_135181361 0.28 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr18_+_9475494 0.28 ENST00000383432.8
ralA binding protein 1
chr2_+_33436304 0.28 ENST00000402538.7
RAS guanyl releasing protein 3
chr2_+_27442365 0.28 ENST00000543753.5
ENST00000288873.7
keratinocyte associated protein 3
chr8_-_94436926 0.28 ENST00000481490.3
fibrinogen silencer binding protein
chr1_-_207032749 0.28 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chr19_-_38253238 0.27 ENST00000587515.5
protein phosphatase 1 regulatory inhibitor subunit 14A
chr9_+_116153783 0.27 ENST00000328252.4
pappalysin 1
chr17_-_41009124 0.27 ENST00000391588.3
keratin associated protein 3-1
chr4_-_122621011 0.27 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr18_-_55510753 0.27 ENST00000543082.5
transcription factor 4
chr18_+_62715526 0.27 ENST00000262719.10
PH domain and leucine rich repeat protein phosphatase 1
chrX_-_54043927 0.27 ENST00000415025.5
ENST00000338946.10
PHD finger protein 8
chr4_+_85475167 0.26 ENST00000503995.5
Rho GTPase activating protein 24
chr8_-_28386073 0.26 ENST00000523095.5
ENST00000522795.1
zinc finger protein 395
chr21_+_29299368 0.26 ENST00000399921.5
BTB domain and CNC homolog 1
chr3_+_159852933 0.26 ENST00000482804.1
schwannomin interacting protein 1
chr17_-_19387170 0.26 ENST00000395592.6
ENST00000299610.5
microfibril associated protein 4
chr5_-_116536458 0.25 ENST00000510263.5
semaphorin 6A
chr12_-_31326142 0.25 ENST00000337682.9
SIN3-HDAC complex associated factor
chr14_+_22598224 0.25 ENST00000428304.6
ENST00000542041.1
ENST00000216327.10
abhydrolase domain containing 4, N-acyl phospholipase B
chr2_+_176157293 0.25 ENST00000683222.1
homeobox D3
chr1_-_206921867 0.25 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr4_-_185775271 0.25 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr20_+_21126037 0.25 ENST00000611685.4
ENST00000616848.4
kizuna centrosomal protein
chr14_+_104801082 0.25 ENST00000342537.8
zinc finger and BTB domain containing 42
chr11_+_31650024 0.25 ENST00000638317.1
elongator acetyltransferase complex subunit 4
chr14_-_91060578 0.25 ENST00000418736.6
ENST00000614987.5
ribosomal protein S6 kinase A5
chrX_-_24647091 0.25 ENST00000356768.8
phosphate cytidylyltransferase 1, choline, beta
chr12_-_86256267 0.25 ENST00000620241.4
MGAT4 family member C
chr22_-_37109703 0.24 ENST00000406856.7
ENST00000676104.1
transmembrane serine protease 6
chr20_+_45406560 0.24 ENST00000372717.5
ENST00000360981.8
dysbindin domain containing 2
chr16_-_57798008 0.24 ENST00000421376.6
kinesin family member C3
chr17_+_69414690 0.24 ENST00000590474.7
mitogen-activated protein kinase kinase 6
chr2_+_111120906 0.24 ENST00000337565.9
ENST00000357757.6
ENST00000308659.12
ENST00000393256.8
ENST00000610735.4
ENST00000615946.4
ENST00000619294.4
ENST00000620862.4
ENST00000621302.4
ENST00000622509.4
ENST00000622612.4
BCL2 like 11
chr3_-_142149515 0.24 ENST00000475734.5
ENST00000467072.5
ENST00000489671.6
transcription factor Dp-2
chr12_+_120302316 0.24 ENST00000536460.1
ENST00000202967.4
sirtuin 4
chr6_-_33200614 0.24 ENST00000374685.8
ENST00000374680.4
retinoid X receptor beta
chr2_-_175168159 0.24 ENST00000392544.5
ENST00000409499.5
ENST00000409833.5
ENST00000264110.7
ENST00000409635.5
ENST00000345739.9
ENST00000426833.7
activating transcription factor 2
chr1_-_206921987 0.24 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chrX_-_54044447 0.24 ENST00000338154.11
PHD finger protein 8
chr9_-_81688354 0.24 ENST00000418319.5
TLE family member 1, transcriptional corepressor
chr21_-_34526850 0.23 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chr11_-_16356538 0.23 ENST00000683767.1
SRY-box transcription factor 6
chr2_-_208025494 0.23 ENST00000457206.1
ENST00000427836.8
pleckstrin homology domain containing M3
chr15_+_81296913 0.23 ENST00000394652.6
interleukin 16
chr17_+_59565598 0.23 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chr6_-_42048648 0.23 ENST00000502771.1
ENST00000508143.5
ENST00000514588.1
ENST00000510503.5
cyclin D3
chr12_+_100473916 0.23 ENST00000549996.5
nuclear receptor subfamily 1 group H member 4
chr12_-_27972725 0.23 ENST00000545234.6
parathyroid hormone like hormone
chr20_+_21125999 0.23 ENST00000620891.4
kizuna centrosomal protein
chr20_+_21125981 0.23 ENST00000619574.4
kizuna centrosomal protein
chr6_+_135181323 0.22 ENST00000367814.8
MYB proto-oncogene, transcription factor
chr8_+_127736220 0.22 ENST00000524013.2
ENST00000621592.8
MYC proto-oncogene, bHLH transcription factor
chr17_-_79952007 0.22 ENST00000574241.6
TBC1 domain family member 16
chr9_-_37465402 0.22 ENST00000307750.5
zinc finger and BTB domain containing 5
chr4_-_86358487 0.22 ENST00000641066.1
ENST00000512689.6
ENST00000641803.1
ENST00000640970.1
ENST00000641983.1
mitogen-activated protein kinase 10
chr18_+_9474994 0.22 ENST00000019317.8
ralA binding protein 1
chr1_+_92080305 0.22 ENST00000342818.4
ENST00000636805.2
BTB domain containing 8
chr20_+_21126074 0.22 ENST00000619189.5
kizuna centrosomal protein
chr1_-_145996567 0.22 ENST00000582401.6
thioredoxin interacting protein
chr5_-_16508990 0.21 ENST00000399793.6
reticulophagy regulator 1
chr2_-_27071628 0.21 ENST00000447619.5
ENST00000429985.1
ENST00000456793.2
oligosaccharyltransferase complex subunit 4, non-catalytic
chr3_+_113897470 0.21 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr8_+_127736046 0.21 ENST00000641036.1
ENST00000377970.6
MYC proto-oncogene, bHLH transcription factor
chr22_+_50170720 0.21 ENST00000159647.9
ENST00000395842.3
pannexin 2
chr10_+_72273914 0.21 ENST00000681898.1
ENST00000307365.4
DNA damage inducible transcript 4
chr4_-_139302460 0.20 ENST00000394223.2
ENST00000676245.1
NADH:ubiquinone oxidoreductase subunit C1
chr5_-_151080978 0.20 ENST00000520931.5
ENST00000521591.6
ENST00000520695.5
ENST00000610535.5
ENST00000518977.5
ENST00000389378.6
ENST00000610874.4
TNFAIP3 interacting protein 1
chr15_+_84237586 0.20 ENST00000512109.1
golgin A6 family like 4
chr6_+_72212802 0.20 ENST00000401910.7
regulating synaptic membrane exocytosis 1
chr10_+_24466487 0.19 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr12_-_92145838 0.19 ENST00000256015.5
BTG anti-proliferation factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.8 GO:1902617 response to fluoride(GO:1902617)
0.2 2.6 GO:0032782 bile acid secretion(GO:0032782)
0.2 0.5 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 0.5 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 0.6 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.9 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 0.4 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.5 GO:2001250 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.9 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:0006196 AMP catabolic process(GO:0006196)
0.1 1.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.4 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.3 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.7 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:2000078 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 1.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.7 GO:0061709 reticulophagy(GO:0061709)
0.1 0.2 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 1.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.2 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.6 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.3 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.2 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.6 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069) intestinal epithelial cell maturation(GO:0060574)
0.1 0.4 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 2.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.1 GO:2000974 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.5 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.1 GO:0019376 galactolipid catabolic process(GO:0019376)
0.0 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0072717 transcription factor catabolic process(GO:0036369) cellular response to actinomycin D(GO:0072717)
0.0 0.5 GO:1903242 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242) positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.7 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.4 GO:0090232 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0048867 stem cell fate determination(GO:0048867)
0.0 0.7 GO:0060004 reflex(GO:0060004)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:2000468 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 1.0 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.0 GO:0045402 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.7 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0072183 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 2.3 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:0042704 uterine wall breakdown(GO:0042704) frontal suture morphogenesis(GO:0060364)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
0.0 0.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 3.6 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034657 GID complex(GO:0034657)
0.2 2.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.9 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.5 GO:0036398 TCR signalosome(GO:0036398)
0.1 1.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.8 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 1.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.4 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0005712 chiasma(GO:0005712)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 4.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 3.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.4 GO:0038201 TOR complex(GO:0038201)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.0 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 3.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.4 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.3 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.4 GO:0002046 opsin binding(GO:0002046)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 1.5 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.3 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.6 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.7 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.0 GO:0016497 substance K receptor activity(GO:0016497)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0043531 ADP binding(GO:0043531)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.0 PID MYC PATHWAY C-MYC pathway
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 4.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.3 PID P73PATHWAY p73 transcription factor network
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 1.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 1.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression