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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOXO4

Z-value: 0.80

Motif logo

Transcription factors associated with FOXO4

Gene Symbol Gene ID Gene Info
ENSG00000184481.17 forkhead box O4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO4hg38_v1_chrX_+_71095838_71095860-0.383.6e-01Click!

Activity profile of FOXO4 motif

Sorted Z-values of FOXO4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_56579555 1.75 ENST00000371250.4
phospholipid phosphatase 3
chr9_-_92424427 1.52 ENST00000375550.5
osteomodulin
chr11_+_114060204 1.48 ENST00000683318.1
zinc finger and BTB domain containing 16
chr10_+_69088096 1.16 ENST00000242465.4
serglycin
chr14_-_59630582 1.13 ENST00000395090.5
reticulon 1
chr6_-_152168291 1.10 ENST00000354674.5
spectrin repeat containing nuclear envelope protein 1
chr6_-_152168349 1.09 ENST00000539504.5
spectrin repeat containing nuclear envelope protein 1
chr4_+_123399488 0.84 ENST00000394339.2
sprouty RTK signaling antagonist 1
chr4_-_158159657 0.71 ENST00000590648.5
golgi associated kinase 1B
chr1_-_145910031 0.68 ENST00000369304.8
integrin subunit alpha 10
chr19_+_18001117 0.66 ENST00000379656.7
arrestin domain containing 2
chr1_-_145910066 0.66 ENST00000539363.2
integrin subunit alpha 10
chr8_-_13276491 0.65 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr21_+_36135071 0.64 ENST00000290354.6
carbonyl reductase 3
chr3_+_148730100 0.62 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr6_-_117425905 0.61 ENST00000368507.8
ROS proto-oncogene 1, receptor tyrosine kinase
chr7_+_120988683 0.61 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr6_-_117425855 0.60 ENST00000368508.7
ROS proto-oncogene 1, receptor tyrosine kinase
chr17_-_69141878 0.57 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr2_+_148021404 0.57 ENST00000638043.2
methyl-CpG binding domain protein 5
chr11_-_27722021 0.57 ENST00000314915.6
brain derived neurotrophic factor
chr5_-_138338325 0.56 ENST00000510119.1
ENST00000513970.5
cell division cycle 25C
chr1_-_182391323 0.53 ENST00000642379.1
glutamate-ammonia ligase
chr7_+_20615653 0.51 ENST00000404938.7
ATP binding cassette subfamily B member 5
chr1_-_182391363 0.50 ENST00000417584.6
glutamate-ammonia ligase
chr4_-_185775271 0.49 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr15_-_52678560 0.48 ENST00000562351.2
ENST00000261844.11
ENST00000399202.8
ENST00000562135.5
family with sequence similarity 214 member A
chr3_+_155080307 0.48 ENST00000360490.7
membrane metalloendopeptidase
chr2_+_232662733 0.46 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr1_-_182391783 0.45 ENST00000331872.11
ENST00000339526.8
glutamate-ammonia ligase
chr11_+_77821125 0.44 ENST00000526415.5
ENST00000393427.6
ENST00000527134.5
ENST00000304716.12
ENST00000630098.2
adipogenesis associated Mth938 domain containing
chr7_+_134866831 0.44 ENST00000435928.1
caldesmon 1
chr6_+_108560906 0.44 ENST00000406360.2
forkhead box O3
chr8_+_69492793 0.42 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr5_-_124746630 0.42 ENST00000513986.2
zinc finger protein 608
chr3_+_155083523 0.42 ENST00000680057.1
membrane metalloendopeptidase
chr10_-_24952573 0.41 ENST00000376378.5
ENST00000376376.3
ENST00000320152.11
phosphoribosyl transferase domain containing 1
chr2_+_108588286 0.41 ENST00000332345.10
LIM zinc finger domain containing 1
chr11_+_77821187 0.40 ENST00000525409.5
adipogenesis associated Mth938 domain containing
chr5_-_65624288 0.40 ENST00000381018.7
ENST00000274327.11
ENST00000231524.14
tripartite motif containing 23
chr7_-_13988863 0.39 ENST00000405358.8
ETS variant transcription factor 1
chr13_+_23570370 0.39 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr2_+_12716893 0.38 ENST00000381465.2
ENST00000155926.9
tribbles pseudokinase 2
chr1_+_150149819 0.37 ENST00000369124.5
pleckstrin homology domain containing O1
chr2_-_191847068 0.37 ENST00000304141.5
caveolae associated protein 2
chr18_+_6834473 0.37 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
Rho GTPase activating protein 28
chr17_-_31858927 0.32 ENST00000579741.1
coordinator of PRMT5 and differentiation stimulator
chr13_-_74133892 0.32 ENST00000377669.7
Kruppel like factor 12
chr2_+_174395721 0.32 ENST00000272732.11
ENST00000458563.5
ENST00000409673.7
ENST00000435964.1
ENST00000424069.5
ENST00000427038.5
secernin 3
chr10_-_48274567 0.32 ENST00000636244.1
ENST00000374201.8
FERM and PDZ domain containing 2
chr6_-_87095059 0.31 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr11_+_77821105 0.30 ENST00000532481.5
adipogenesis associated Mth938 domain containing
chr2_-_2326378 0.30 ENST00000647618.1
myelin transcription factor 1 like
chr7_+_151341764 0.30 ENST00000413040.7
ENST00000470229.6
ENST00000568733.6
negative regulator of ubiquitin like proteins 1
chr6_-_167157980 0.30 ENST00000366834.2
G protein-coupled receptor 31
chr10_-_24721866 0.30 ENST00000416305.1
ENST00000320481.10
Rho GTPase activating protein 21
chr15_-_52679347 0.29 ENST00000566768.5
ENST00000561543.5
ENST00000619572.5
family with sequence similarity 214 member A
chr1_+_96722628 0.29 ENST00000675401.1
polypyrimidine tract binding protein 2
chr15_-_55365231 0.29 ENST00000568543.1
cell cycle progression 1
chr4_-_151227881 0.28 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr19_+_49877660 0.28 ENST00000535102.6
TBC1 domain family member 17
chr6_+_36676489 0.28 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr19_+_49877694 0.27 ENST00000221543.10
TBC1 domain family member 17
chr20_+_18145083 0.27 ENST00000489634.2
lysine acetyltransferase 14
chr10_+_91220603 0.27 ENST00000336126.6
polycomb group ring finger 5
chr17_-_31858952 0.27 ENST00000378634.6
coordinator of PRMT5 and differentiation stimulator
chr19_-_58150772 0.26 ENST00000597186.5
ENST00000598312.6
zinc finger protein 329
chr5_-_131796921 0.25 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr5_-_134174765 0.25 ENST00000520417.1
S-phase kinase associated protein 1
chr2_-_165203870 0.25 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr2_+_65056382 0.25 ENST00000377990.7
ENST00000537589.1
ENST00000260569.4
centrosomal protein 68
chr3_-_186109067 0.25 ENST00000306376.10
ETS variant transcription factor 5
chr5_-_131797030 0.25 ENST00000615660.4
folliculin interacting protein 1
chr1_-_241640347 0.25 ENST00000366554.3
ENST00000366553.3
opsin 3
CHM like Rab escort protein
chr13_+_97434154 0.25 ENST00000245304.5
RAP2A, member of RAS oncogene family
chr5_-_126595237 0.25 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr16_-_15643024 0.24 ENST00000540441.6
meiosis regulator and mRNA stability factor 1
chr2_-_55334529 0.24 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chr12_+_99647749 0.24 ENST00000324341.2
family with sequence similarity 71 member C
chr1_-_43389768 0.23 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chr11_-_89490715 0.23 ENST00000528341.5
NADPH oxidase 4
chr12_+_79045625 0.22 ENST00000552744.5
synaptotagmin 1
chr2_-_2326210 0.22 ENST00000647755.1
myelin transcription factor 1 like
chr2_+_108588453 0.22 ENST00000393310.5
LIM zinc finger domain containing 1
chr9_-_83817632 0.22 ENST00000376365.7
ENST00000376371.7
G kinase anchoring protein 1
chr5_-_126595185 0.22 ENST00000510111.6
ENST00000635851.1
ENST00000637964.1
ENST00000413020.6
ENST00000637782.1
ENST00000409134.8
ENST00000637272.1
ENST00000636879.1
ENST00000636743.1
ENST00000636886.1
ENST00000509270.2
aldehyde dehydrogenase 7 family member A1
chr1_-_53940100 0.21 ENST00000371376.1
heat shock protein family B (small) member 11
chr3_+_156674579 0.21 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr14_+_22598224 0.20 ENST00000428304.6
ENST00000542041.1
ENST00000216327.10
abhydrolase domain containing 4, N-acyl phospholipase B
chr2_-_165204042 0.20 ENST00000283254.12
ENST00000453007.1
sodium voltage-gated channel alpha subunit 3
chr12_+_12725897 0.20 ENST00000326765.10
apolipoprotein L domain containing 1
chr5_+_136132772 0.20 ENST00000545279.6
ENST00000507118.5
ENST00000511116.5
ENST00000545620.5
ENST00000509297.6
SMAD family member 5
chr9_-_107489754 0.19 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr3_-_142149515 0.19 ENST00000475734.5
ENST00000467072.5
ENST00000489671.6
transcription factor Dp-2
chr17_+_19648792 0.19 ENST00000630662.2
aldehyde dehydrogenase 3 family member A2
chr5_+_137867852 0.19 ENST00000421631.6
ENST00000239926.9
myotilin
chr7_-_6059139 0.19 ENST00000446699.1
ENST00000199389.11
eukaryotic translation initiation factor 2 alpha kinase 1
chr1_-_19799872 0.19 ENST00000294543.11
transmembrane and coiled-coil domains 4
chr6_+_101398788 0.19 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
glutamate ionotropic receptor kainate type subunit 2
chr21_-_26967057 0.19 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr7_-_138627444 0.19 ENST00000463557.1
SVOP like
chr2_+_201116143 0.18 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr10_+_113709261 0.18 ENST00000672138.1
ENST00000452490.3
caspase 7
chr12_-_7444139 0.17 ENST00000416109.2
ENST00000313599.8
CD163 molecule like 1
chr7_-_38354517 0.17 ENST00000390345.2
T cell receptor gamma variable 4
chr1_+_236523417 0.17 ENST00000341872.10
ENST00000416919.6
ENST00000450372.6
galectin 8
chr20_+_17699942 0.17 ENST00000427254.1
ENST00000377805.7
BANF family member 2
chr20_+_45406560 0.17 ENST00000372717.5
ENST00000360981.8
dysbindin domain containing 2
chr4_-_139302460 0.17 ENST00000394223.2
ENST00000676245.1
NADH:ubiquinone oxidoreductase subunit C1
chr12_+_103587266 0.17 ENST00000388887.7
stabilin 2
chr1_-_120100688 0.17 ENST00000652264.1
notch receptor 2
chr1_-_47190013 0.17 ENST00000294338.7
PDZK1 interacting protein 1
chr1_+_174875505 0.16 ENST00000486220.5
RAB GTPase activating protein 1 like
chr22_-_37109703 0.16 ENST00000406856.7
ENST00000676104.1
transmembrane serine protease 6
chr6_+_36676455 0.16 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr12_-_102197827 0.16 ENST00000329406.5
pro-melanin concentrating hormone
chr14_-_60724300 0.16 ENST00000556952.3
ENST00000216513.5
SIX homeobox 4
chr1_-_227318125 0.16 ENST00000366764.7
CDC42 binding protein kinase alpha
chr10_+_84424919 0.16 ENST00000543283.2
ENST00000494586.5
coiled-coil serine rich protein 2
chr5_-_42811884 0.16 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr3_+_101574157 0.16 ENST00000265260.8
ENST00000469941.5
ENST00000627393.1
PEST proteolytic signal containing nuclear protein
chr18_+_75210755 0.16 ENST00000322038.5
teashirt zinc finger homeobox 1
chr4_-_151325488 0.15 ENST00000604030.7
SH3 domain containing 19
chr19_-_12610799 0.15 ENST00000311437.11
zinc finger protein 490
chr18_+_75210789 0.15 ENST00000580243.3
teashirt zinc finger homeobox 1
chr1_+_151766655 0.15 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr4_-_185775890 0.15 ENST00000437304.6
sorbin and SH3 domain containing 2
chr15_-_40307825 0.15 ENST00000456256.6
ENST00000557821.5
phospholipase C beta 2
chr5_+_138338256 0.14 ENST00000513056.5
ENST00000239906.10
ENST00000511276.1
family with sequence similarity 53 member C
chr5_-_179620933 0.14 ENST00000521173.5
heterogeneous nuclear ribonucleoprotein H1
chr1_+_10430070 0.14 ENST00000400900.6
CENPS-CORT readthrough
chr5_-_134371004 0.14 ENST00000521755.1
ENST00000523054.5
ENST00000518409.1
cyclin dependent kinase like 3
novel transcript
chr9_-_15472732 0.14 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chrX_+_106802660 0.14 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1 domain family member 8B
chr1_-_101846957 0.14 ENST00000338858.9
olfactomedin 3
chr4_-_139302516 0.14 ENST00000394228.5
ENST00000539387.5
NADH:ubiquinone oxidoreductase subunit C1
chr3_+_159852933 0.13 ENST00000482804.1
schwannomin interacting protein 1
chr17_+_6755834 0.13 ENST00000346752.8
XIAP associated factor 1
chr5_-_131796965 0.13 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr8_-_42768602 0.13 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr20_+_34516394 0.13 ENST00000357156.7
ENST00000300469.13
ENST00000374846.3
dynein light chain roadblock-type 1
chr2_+_235494024 0.13 ENST00000304032.13
ENST00000409457.5
ENST00000336665.9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr9_+_127611760 0.13 ENST00000625363.2
ENST00000626539.3
syntaxin binding protein 1
chr2_-_24084292 0.13 ENST00000413037.1
ENST00000407482.5
tumor protein p53 inducible protein 3
chr19_-_49877279 0.13 ENST00000391832.7
ENST00000344175.10
AKT1 substrate 1
chr19_+_49877425 0.13 ENST00000622860.4
TBC1 domain family member 17
chr14_+_101809795 0.13 ENST00000350249.7
ENST00000557621.5
ENST00000556946.1
protein phosphatase 2 regulatory subunit B'gamma
chr5_-_108367860 0.13 ENST00000496714.2
F-box and leucine rich repeat protein 17
chr11_-_89491131 0.13 ENST00000343727.9
ENST00000531342.5
ENST00000375979.7
NADPH oxidase 4
chr8_-_42768781 0.13 ENST00000276410.7
cholinergic receptor nicotinic alpha 6 subunit
chr6_-_42048648 0.12 ENST00000502771.1
ENST00000508143.5
ENST00000514588.1
ENST00000510503.5
cyclin D3
chr1_-_159714581 0.12 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr9_-_13175824 0.12 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr4_-_21948733 0.12 ENST00000447367.6
ENST00000382152.7
potassium voltage-gated channel interacting protein 4
chr11_-_83034195 0.12 ENST00000531021.5
RAB30, member RAS oncogene family
chr17_+_2337622 0.12 ENST00000574563.5
small G protein signaling modulator 2
chr12_-_100092890 0.12 ENST00000550544.5
ENST00000551980.1
ENST00000548045.5
ENST00000545232.6
ENST00000551973.5
UHRF1 binding protein 1 like
chr7_-_33100886 0.11 ENST00000448915.1
RP9 pre-mRNA splicing factor
chr11_-_46617170 0.11 ENST00000326737.3
harbinger transposase derived 1
chr3_-_45884685 0.11 ENST00000684620.1
leucine zipper transcription factor like 1
chr17_+_35147807 0.11 ENST00000394570.7
ENST00000268876.9
unc-45 myosin chaperone B
chr19_+_52220983 0.11 ENST00000391791.4
protein phosphatase 2 scaffold subunit Aalpha
chr20_-_63951122 0.11 ENST00000369908.9
uridine-cytidine kinase 1 like 1
chr10_+_102644990 0.11 ENST00000645961.1
tripartite motif containing 8
chr14_-_103521342 0.11 ENST00000553610.5
creatine kinase B
chr2_-_36966503 0.11 ENST00000263918.9
striatin
chr17_+_2337480 0.11 ENST00000268989.8
ENST00000426855.6
small G protein signaling modulator 2
chr19_+_12610912 0.11 ENST00000446165.2
ENST00000343325.9
zinc finger protein 791
chr16_+_28846674 0.10 ENST00000322610.12
SH2B adaptor protein 1
chr2_-_24123251 0.10 ENST00000313213.5
ENST00000436622.1
profilin family member 4
chr12_+_6772512 0.10 ENST00000441671.6
ENST00000203629.3
lymphocyte activating 3
chr19_-_36528232 0.10 ENST00000592282.1
ENST00000523638.6
zinc finger protein 260
chr19_-_36032799 0.10 ENST00000592017.5
ENST00000360535.9
CAP-Gly domain containing linker protein 3
chr1_+_23691742 0.10 ENST00000374550.8
ENST00000643754.2
ribosomal protein L11
chr19_-_40226682 0.10 ENST00000430325.7
ENST00000599263.6
cyclin P
chr8_-_144529048 0.10 ENST00000527462.1
ENST00000313465.5
ENST00000524821.6
chromosome 8 open reading frame 82
chr8_-_143986425 0.10 ENST00000313059.9
ENST00000524918.5
ENST00000313028.12
ENST00000525773.5
poly(ADP-ribose) polymerase family member 10
chr7_-_112939773 0.10 ENST00000297145.9
base methyltransferase of 25S rRNA 2 homolog
chr3_-_28348805 0.10 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr5_+_98769273 0.10 ENST00000308234.11
repulsive guidance molecule BMP co-receptor b
chr17_-_59151794 0.10 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr20_+_56248732 0.10 ENST00000243911.2
melanocortin 3 receptor
chr16_+_1680337 0.10 ENST00000566691.5
ENST00000382710.8
Jupiter microtubule associated homolog 2
chr6_+_168017873 0.10 ENST00000351261.4
ENST00000354419.6
kinesin family member 25
chr9_+_5510492 0.09 ENST00000397747.5
programmed cell death 1 ligand 2
chr2_-_174395640 0.09 ENST00000342016.8
corepressor interacting with RBPJ, CIR1
chr8_+_49072335 0.09 ENST00000399653.8
ENST00000522267.6
ENST00000303202.8
pancreatic progenitor cell differentiation and proliferation factor like
chr3_-_151203201 0.09 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr13_-_38990824 0.09 ENST00000379631.9
stomatin like 3
chr12_+_53985138 0.09 ENST00000303460.5
homeobox C10
chr14_-_92106607 0.09 ENST00000340660.10
ENST00000393287.9
ENST00000429774.6
ENST00000545170.5
ENST00000620536.4
ENST00000621269.4
ataxin 3
chr18_-_33136075 0.09 ENST00000581852.5
coiled-coil domain containing 178
chr8_-_71547626 0.09 ENST00000647540.1
ENST00000644229.1
EYA transcriptional coactivator and phosphatase 1
chr8_-_100336184 0.09 ENST00000519527.5
ENST00000522369.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr19_+_13795434 0.09 ENST00000254323.6
zinc finger SWIM-type containing 4
chr14_-_55411817 0.08 ENST00000247178.6
autophagy related 14
chr2_-_127858107 0.08 ENST00000409955.1
ENST00000272645.9
RNA polymerase II subunit D
chr8_-_61689768 0.08 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
aspartate beta-hydroxylase
chr13_-_36370111 0.08 ENST00000650221.1
spartin
chr17_-_42745025 0.08 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.4 1.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.7 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 2.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 0.8 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 1.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.2 0.6 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.2 0.5 GO:0048058 compound eye corneal lens development(GO:0048058)
0.2 0.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 1.7 GO:0008354 germ cell migration(GO:0008354)
0.1 0.6 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.6 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.5 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 1.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.4 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.6 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0015847 putrescine transport(GO:0015847)
0.0 0.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.2 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 0.2 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0061055 myotome development(GO:0061055) skeletal muscle fiber differentiation(GO:0098528)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0051232 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:1905026 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.8 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.5 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 2.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.5 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 1.0 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 1.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 0.6 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 1.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 2.1 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
0.0 0.1 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.0 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.0 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL