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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOXQ1

Z-value: 1.07

Motif logo

Transcription factors associated with FOXQ1

Gene Symbol Gene ID Gene Info
ENSG00000164379.7 forkhead box Q1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXQ1hg38_v1_chr6_+_1312090_1312105-0.849.1e-03Click!

Activity profile of FOXQ1 motif

Sorted Z-values of FOXQ1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91180365 2.92 ENST00000547937.5
decorin
chr2_+_151357583 2.01 ENST00000243347.5
TNF alpha induced protein 6
chr3_+_157436842 1.93 ENST00000295927.4
pentraxin 3
chr2_-_187554351 1.55 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr1_-_72100930 1.52 ENST00000306821.3
neuronal growth regulator 1
chr5_-_20575850 1.46 ENST00000507958.5
cadherin 18
chr5_+_141150012 1.39 ENST00000231136.4
ENST00000622991.1
protocadherin beta 6
chr4_-_69760596 1.25 ENST00000510821.1
sulfotransferase family 1B member 1
chr1_-_56579555 1.15 ENST00000371250.4
phospholipid phosphatase 3
chr2_-_189179754 1.12 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr4_-_69760610 1.11 ENST00000310613.8
sulfotransferase family 1B member 1
chr20_+_13008919 0.98 ENST00000399002.7
ENST00000434210.5
serine palmitoyltransferase long chain base subunit 3
chr10_-_77637444 0.95 ENST00000639205.1
ENST00000639498.1
ENST00000372408.7
ENST00000372403.9
ENST00000640626.1
ENST00000404857.6
ENST00000638252.1
ENST00000640029.1
ENST00000640934.1
ENST00000639823.1
ENST00000372437.6
ENST00000639344.1
potassium calcium-activated channel subfamily M alpha 1
chr3_+_69936583 0.94 ENST00000314557.10
ENST00000394351.9
melanocyte inducing transcription factor
chr1_-_145910031 0.88 ENST00000369304.8
integrin subunit alpha 10
chr14_+_75632610 0.87 ENST00000555027.1
FLVCR heme transporter 2
chr8_+_78516329 0.87 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr9_-_20382461 0.83 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr1_-_145910066 0.82 ENST00000539363.2
integrin subunit alpha 10
chr6_-_87095059 0.78 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr12_+_1629197 0.77 ENST00000397196.7
Wnt family member 5B
chr5_-_111756245 0.77 ENST00000447165.6
neuronal regeneration related protein
chr7_+_93921720 0.74 ENST00000248564.6
G protein subunit gamma 11
chr8_+_69492793 0.73 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr12_-_15221394 0.68 ENST00000537647.5
ENST00000256953.6
ENST00000546331.5
RAS like estrogen regulated growth inhibitor
chrX_+_9912434 0.65 ENST00000418909.6
shroom family member 2
chr12_-_10453330 0.64 ENST00000347831.9
ENST00000359151.8
killer cell lectin like receptor C1
chr20_+_36214373 0.63 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chr5_+_141192330 0.63 ENST00000239446.6
protocadherin beta 10
chr18_-_27990256 0.60 ENST00000675173.1
cadherin 2
chr5_-_41510623 0.60 ENST00000328457.5
phosphatidylinositol specific phospholipase C X domain containing 3
chr1_+_162632454 0.57 ENST00000367921.8
ENST00000367922.7
discoidin domain receptor tyrosine kinase 2
chr3_+_155083889 0.57 ENST00000680282.1
membrane metalloendopeptidase
chr9_-_121050264 0.56 ENST00000223642.3
complement C5
chr1_-_27672178 0.55 ENST00000339145.8
ENST00000361157.11
ENST00000362020.4
ENST00000679644.1
interferon alpha inducible protein 6
chr4_-_99352754 0.55 ENST00000639454.1
alcohol dehydrogenase 1B (class I), beta polypeptide
chr1_-_23868279 0.54 ENST00000374479.4
alpha-L-fucosidase 1
chr15_+_41256907 0.54 ENST00000560965.1
calcineurin like EF-hand protein 1
chr2_-_187554473 0.54 ENST00000453013.5
ENST00000417013.5
tissue factor pathway inhibitor
chr19_+_49527988 0.52 ENST00000270645.8
reticulocalbin 3
chr10_-_48604952 0.51 ENST00000417912.6
Rho GTPase activating protein 22
chr18_+_7754959 0.51 ENST00000400053.8
protein tyrosine phosphatase receptor type M
chr2_-_144517663 0.51 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr5_+_141364153 0.51 ENST00000518069.2
protocadherin gamma subfamily A, 5
chr4_-_118352967 0.49 ENST00000296498.3
serine protease 12
chr19_+_926001 0.48 ENST00000263620.8
AT-rich interaction domain 3A
chr1_-_53940100 0.48 ENST00000371376.1
heat shock protein family B (small) member 11
chr5_-_41510554 0.48 ENST00000377801.8
phosphatidylinositol specific phospholipase C X domain containing 3
chr3_+_155083523 0.48 ENST00000680057.1
membrane metalloendopeptidase
chr17_-_445939 0.48 ENST00000329099.4
refilin B
chr7_+_134843884 0.47 ENST00000445569.6
caldesmon 1
chr12_-_71157872 0.46 ENST00000546561.2
tetraspanin 8
chr4_-_158173042 0.46 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr14_+_88005128 0.46 ENST00000267549.5
G protein-coupled receptor 65
chr10_-_48605032 0.46 ENST00000249601.9
Rho GTPase activating protein 22
chrX_+_10158448 0.46 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr4_-_158173004 0.45 ENST00000585682.6
golgi associated kinase 1B
chr3_+_152300135 0.44 ENST00000465907.6
ENST00000492948.5
ENST00000485509.5
ENST00000464596.5
muscleblind like splicing regulator 1
chr5_-_88785493 0.42 ENST00000503554.4
myocyte enhancer factor 2C
chr14_-_73027077 0.41 ENST00000553891.5
ENST00000556143.6
zinc finger FYVE-type containing 1
chr1_+_61077219 0.41 ENST00000407417.7
nuclear factor I A
chr15_-_63157464 0.40 ENST00000330964.10
ENST00000635699.1
ENST00000439025.1
ribosomal protein S27 like
chr2_-_202871253 0.39 ENST00000435143.5
islet cell autoantigen 1 like
chr4_-_185775271 0.39 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr9_-_120477354 0.39 ENST00000416449.5
CDK5 regulatory subunit associated protein 2
chrX_-_100410264 0.39 ENST00000373034.8
protocadherin 19
chr12_+_18262730 0.37 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr5_+_141364231 0.37 ENST00000611914.1
protocadherin gamma subfamily A, 5
chr11_+_5689780 0.37 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chr14_+_50533026 0.37 ENST00000441560.6
atlastin GTPase 1
chr19_+_49930219 0.36 ENST00000596658.1
activating transcription factor 5
chr4_-_139280179 0.36 ENST00000398955.2
mitochondria localized glutamic acid rich protein
chr7_-_139716980 0.36 ENST00000342645.7
homeodomain interacting protein kinase 2
chr2_+_200440649 0.36 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr14_-_73027117 0.35 ENST00000318876.9
zinc finger FYVE-type containing 1
chr19_-_58353482 0.34 ENST00000263100.8
alpha-1-B glycoprotein
chr1_+_103655760 0.34 ENST00000370083.9
amylase alpha 1A
chr12_-_122395422 0.33 ENST00000540304.6
CAP-Gly domain containing linker protein 1
chr6_+_135851681 0.33 ENST00000308191.11
phosphodiesterase 7B
chr1_+_171090892 0.33 ENST00000367755.9
ENST00000479749.1
flavin containing dimethylaniline monoxygenase 3
chr11_+_20022550 0.32 ENST00000533917.5
neuron navigator 2
chr7_+_143288215 0.32 ENST00000619992.4
ENST00000310447.10
caspase 2
chr5_+_141338753 0.31 ENST00000528330.2
ENST00000394576.3
protocadherin gamma subfamily A, 2
chr2_+_108621260 0.30 ENST00000409441.5
LIM zinc finger domain containing 1
chr2_-_105438503 0.30 ENST00000393352.7
ENST00000607522.1
four and a half LIM domains 2
chr7_-_138627444 0.30 ENST00000463557.1
SVOP like
chr5_-_88823763 0.30 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr15_-_55365231 0.30 ENST00000568543.1
cell cycle progression 1
chr6_+_132570322 0.29 ENST00000275198.1
trace amine associated receptor 6
chr14_+_50560137 0.29 ENST00000358385.12
atlastin GTPase 1
chr4_+_38867677 0.29 ENST00000510213.5
ENST00000515037.5
family with sequence similarity 114 member A1
chr16_-_31065011 0.29 ENST00000539836.3
ENST00000535577.5
ENST00000442862.2
zinc finger protein 668
chr3_-_114624193 0.28 ENST00000481632.5
zinc finger and BTB domain containing 20
chr1_+_174875505 0.28 ENST00000486220.5
RAB GTPase activating protein 1 like
chr19_-_10335773 0.28 ENST00000592439.1
intercellular adhesion molecule 3
chr1_+_103617427 0.28 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr11_-_124800630 0.28 ENST00000239614.8
ENST00000674284.1
Myb/SANT DNA binding domain containing 2
chr5_+_141245384 0.27 ENST00000623671.1
ENST00000231173.6
protocadherin beta 15
chr11_+_73308237 0.27 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr3_-_114759115 0.26 ENST00000471418.5
zinc finger and BTB domain containing 20
chr1_+_103749898 0.26 ENST00000622339.5
amylase alpha 1C
chr18_+_68798065 0.26 ENST00000360242.9
coiled-coil domain containing 102B
chr14_-_73950393 0.25 ENST00000651776.1
FAM161 centrosomal protein B
chr10_+_79703227 0.25 ENST00000429828.5
ENST00000372321.5
NUT family member 2B
chr10_+_15043937 0.25 ENST00000378228.8
ENST00000378217.3
oleoyl-ACP hydrolase
chr5_+_72848161 0.25 ENST00000506351.6
transportin 1
chr11_+_65945445 0.23 ENST00000532620.5
testis specific 10 interacting protein
chr20_+_58389197 0.23 ENST00000475243.6
ENST00000395802.7
VAMP associated protein B and C
chr20_-_45667177 0.23 ENST00000618797.4
WAP four-disulfide core domain 11
chr14_-_89412025 0.23 ENST00000553840.5
ENST00000556916.5
forkhead box N3
chr14_-_106811131 0.23 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr5_+_72848115 0.23 ENST00000679378.1
transportin 1
chr1_+_60865259 0.22 ENST00000371191.5
nuclear factor I A
chr15_+_91100194 0.22 ENST00000394232.6
synaptic vesicle glycoprotein 2B
chr3_-_179259208 0.22 ENST00000485523.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr12_-_71157992 0.22 ENST00000247829.8
tetraspanin 8
chr10_-_91909476 0.22 ENST00000311575.6
fibroblast growth factor binding protein 3
chr16_+_22490337 0.21 ENST00000415833.6
nuclear pore complex interacting protein family member B5
chrX_-_72305892 0.21 ENST00000450875.5
ENST00000417400.1
ENST00000431381.5
ENST00000445983.5
ENST00000651998.1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr5_+_141208697 0.21 ENST00000624949.1
ENST00000622978.1
ENST00000239450.4
protocadherin beta 12
chr20_+_49812697 0.21 ENST00000417961.5
solute carrier family 9 member A8
chr7_+_28412511 0.20 ENST00000357727.7
cAMP responsive element binding protein 5
chr1_+_74235377 0.20 ENST00000326637.8
TNNI3 interacting kinase
chr20_+_31514410 0.20 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr11_-_55936400 0.20 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr2_-_202870862 0.20 ENST00000454326.5
ENST00000432273.5
ENST00000450143.5
ENST00000411681.5
islet cell autoantigen 1 like
chr11_+_72080313 0.20 ENST00000307198.11
ENST00000538413.6
ENST00000642648.1
ENST00000289488.7
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr17_-_48613468 0.20 ENST00000498634.2
homeobox B8
chr3_+_69936629 0.20 ENST00000394348.2
ENST00000531774.1
melanocyte inducing transcription factor
chr1_+_236523417 0.19 ENST00000341872.10
ENST00000416919.6
ENST00000450372.6
galectin 8
chr6_-_130956371 0.19 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
erythrocyte membrane protein band 4.1 like 2
chr16_+_4734519 0.19 ENST00000299320.10
chromosome 16 open reading frame 71
chr15_-_56465130 0.19 ENST00000260453.4
meiosis specific nuclear structural 1
chr5_-_131796921 0.19 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr14_-_91732059 0.18 ENST00000553329.5
ENST00000256343.8
cation channel sperm associated auxiliary subunit beta
chr11_-_47426419 0.18 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr19_-_7294406 0.18 ENST00000302850.10
insulin receptor
chrX_+_109535775 0.18 ENST00000218004.5
nuclear transport factor 2 like export factor 2
chr1_+_84164962 0.18 ENST00000614872.4
ENST00000394839.6
protein kinase cAMP-activated catalytic subunit beta
chr1_+_27773189 0.18 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr15_+_31366138 0.18 ENST00000558844.1
Kruppel like factor 13
chr17_-_41065879 0.18 ENST00000394015.3
keratin associated protein 2-4
chrX_+_88747225 0.18 ENST00000276127.9
ENST00000373111.5
CPX chromosome region candidate 1
chr7_+_48171451 0.18 ENST00000435803.6
ATP binding cassette subfamily A member 13
chr16_+_14708944 0.18 ENST00000526520.5
ENST00000531598.6
nuclear pore complex interacting protein family member A3
chr5_+_136132772 0.18 ENST00000545279.6
ENST00000507118.5
ENST00000511116.5
ENST00000545620.5
ENST00000509297.6
SMAD family member 5
chr5_-_160419059 0.18 ENST00000297151.9
ENST00000519349.5
ENST00000520664.1
SLU7 homolog, splicing factor
chr12_-_49189053 0.17 ENST00000550767.6
ENST00000546918.1
ENST00000679733.1
ENST00000552924.2
ENST00000301071.12
tubulin alpha 1a
chr6_-_29005313 0.17 ENST00000377179.4
zinc finger protein 311
chr21_+_32298849 0.17 ENST00000303645.10
melanocortin 2 receptor accessory protein
chr11_+_30323077 0.17 ENST00000282032.4
ADP ribosylation factor like GTPase 14 effector protein
chr2_+_85354720 0.17 ENST00000409331.6
ENST00000409344.7
ENST00000393852.8
ENST00000409013.8
ENST00000315658.11
ENST00000462891.7
ELMO domain containing 3
chr3_+_107377433 0.17 ENST00000261058.3
coiled-coil domain containing 54
chr13_-_38990824 0.17 ENST00000379631.9
stomatin like 3
chr1_+_220748297 0.17 ENST00000366913.8
mitochondrial amidoxime reducing component 2
chr10_+_35195843 0.17 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr1_+_196977550 0.16 ENST00000256785.5
complement factor H related 5
chr12_-_91111460 0.16 ENST00000266718.5
lumican
chr10_-_103153609 0.16 ENST00000675985.1
5'-nucleotidase, cytosolic II
chr13_-_38990856 0.16 ENST00000423210.1
stomatin like 3
chrX_-_119943732 0.16 ENST00000371410.5
NFKB activating protein
chr10_-_30999469 0.16 ENST00000538351.6
zinc finger protein 438
chr5_+_119476530 0.16 ENST00000645099.1
ENST00000513628.5
hydroxysteroid 17-beta dehydrogenase 4
chr10_+_80131660 0.16 ENST00000372270.6
placenta associated 9
chr12_-_26833143 0.16 ENST00000381340.8
inositol 1,4,5-trisphosphate receptor type 2
chr12_+_109116581 0.16 ENST00000338432.11
acetyl-CoA carboxylase beta
chr1_+_84164370 0.15 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
protein kinase cAMP-activated catalytic subunit beta
chr1_-_94925759 0.15 ENST00000415017.1
ENST00000545882.5
calponin 3
chr20_-_3204633 0.15 ENST00000354488.8
ENST00000380201.2
DDRGK domain containing 1
chr19_+_57633161 0.15 ENST00000541801.5
ENST00000347302.7
ENST00000240731.5
ENST00000254182.11
ENST00000391703.3
zinc finger protein 211
chr3_+_156674579 0.15 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr16_+_4734457 0.15 ENST00000590191.1
chromosome 16 open reading frame 71
chr1_+_113929600 0.15 ENST00000369558.5
ENST00000369561.8
homeodomain interacting protein kinase 1
chr10_+_70404129 0.15 ENST00000373218.5
eukaryotic translation initiation factor 4E binding protein 2
chr1_-_70354673 0.15 ENST00000370944.9
ENST00000262346.6
ankyrin repeat domain 13C
chr3_+_63967738 0.15 ENST00000484332.1
ataxin 7
chr9_+_69820827 0.15 ENST00000527647.5
ENST00000480564.1
chromosome 9 open reading frame 135
chr22_-_50245016 0.15 ENST00000248846.10
tubulin gamma complex associated protein 6
chr4_-_21948733 0.15 ENST00000447367.6
ENST00000382152.7
potassium voltage-gated channel interacting protein 4
chr8_+_7836433 0.14 ENST00000314265.3
defensin beta 104A
chr10_+_21524670 0.14 ENST00000631589.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr12_+_121132869 0.14 ENST00000328963.10
purinergic receptor P2X 7
chr11_-_615570 0.14 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr11_+_65027402 0.14 ENST00000377244.8
ENST00000534637.5
ENST00000524831.5
sorting nexin 15
chr19_+_36687579 0.14 ENST00000682579.1
ENST00000536254.6
zinc finger protein 567
chr3_+_184812138 0.14 ENST00000287546.8
VPS8 subunit of CORVET complex
chr2_+_73892967 0.14 ENST00000409731.7
ENST00000409918.5
ENST00000442912.5
ENST00000345517.8
ENST00000409624.1
actin gamma 2, smooth muscle
chr3_+_184812159 0.14 ENST00000625842.3
ENST00000436792.6
ENST00000446204.6
ENST00000422105.5
VPS8 subunit of CORVET complex
chr14_-_60724300 0.14 ENST00000556952.3
ENST00000216513.5
SIX homeobox 4
chr2_-_174764407 0.14 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr14_-_106627685 0.14 ENST00000390629.3
immunoglobulin heavy variable 4-59
chrX_-_109482075 0.14 ENST00000218006.3
guanylate cyclase 2F, retinal
chr10_+_35195124 0.14 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
cAMP responsive element modulator
chr13_+_75804270 0.14 ENST00000447038.5
LIM domain 7
chr4_+_164754116 0.13 ENST00000507311.1
small integral membrane protein 31
chr17_-_66220630 0.13 ENST00000585162.1
apolipoprotein H
chr18_-_12656716 0.13 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr19_+_44212525 0.13 ENST00000391961.6
ENST00000621083.4
ENST00000313040.12
ENST00000586228.5
ENST00000588219.5
ENST00000589707.5
ENST00000588394.5
ENST00000589005.5
zinc finger protein 227
chr11_-_26572130 0.13 ENST00000527569.1
mucin 15, cell surface associated
chr3_+_159273235 0.13 ENST00000638749.1
IQCJ-SCHIP1 readthrough

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXQ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.4 1.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 1.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 3.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 2.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 1.0 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.5 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.7 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.1 GO:0008354 germ cell migration(GO:0008354)
0.1 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.9 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.0 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.4 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 1.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.5 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 0.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.2 GO:0061055 myotome development(GO:0061055)
0.1 0.2 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.5 GO:0006067 ethanol metabolic process(GO:0006067)
0.0 0.2 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 1.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.6 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.5 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.8 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.7 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 1.1 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117) positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.5 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.0 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.5 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 1.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.9 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.0 GO:0072076 nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.7 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 2.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.8 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.1 0.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 3.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242) mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 1.2 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 1.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 1.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 0.8 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.9 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1 0.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.2 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 2.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0043559 insulin-like growth factor II binding(GO:0031995) insulin binding(GO:0043559)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions