Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
GLI3 | hg38_v1_chr7_-_42152396_42152440, hg38_v1_chr7_-_42237187_42237216 | -0.49 | 2.1e-01 | Click! |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr18_+_23949847 Show fit | 4.10 |
ENST00000588004.1
|
laminin subunit alpha 3 |
|
chr19_-_50953063 Show fit | 2.16 |
ENST00000391809.6
|
kallikrein related peptidase 5 |
|
chr19_-_50953093 Show fit | 2.15 |
ENST00000593428.5
|
kallikrein related peptidase 5 |
|
chr1_-_161021096 Show fit | 2.14 |
ENST00000537746.1
ENST00000368026.11 |
F11 receptor |
|
chr6_+_125219804 Show fit | 2.13 |
ENST00000524679.1
|
TPD52 like 1 |
|
chr12_-_52493250 Show fit | 2.07 |
ENST00000330722.7
|
keratin 6A |
|
chr19_-_50952942 Show fit | 2.01 |
ENST00000594846.1
ENST00000336334.8 |
kallikrein related peptidase 5 |
|
chr6_-_106975309 Show fit | 1.96 |
ENST00000615659.1
|
CD24 molecule |
|
chr1_+_183186238 Show fit | 1.92 |
ENST00000493293.5
ENST00000264144.5 |
laminin subunit gamma 2 |
|
chr12_-_52473798 Show fit | 1.78 |
ENST00000252250.7
|
keratin 6C |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 6.3 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
0.2 | 6.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
1.3 | 5.3 | GO:0032600 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
0.0 | 3.2 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
0.0 | 3.1 | GO:0070268 | cornification(GO:0070268) |
0.0 | 3.1 | GO:0046330 | positive regulation of JNK cascade(GO:0046330) |
0.6 | 2.3 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
0.5 | 2.1 | GO:0001897 | cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710) |
0.0 | 2.1 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.1 | 2.0 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 6.3 | GO:0097209 | epidermal lamellar body(GO:0097209) |
0.1 | 6.2 | GO:0045095 | keratin filament(GO:0045095) |
0.2 | 5.3 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.6 | 4.1 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.0 | 3.6 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 3.0 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.0 | 2.7 | GO:0001650 | fibrillar center(GO:0001650) |
0.1 | 2.6 | GO:0005922 | connexon complex(GO:0005922) |
0.2 | 2.1 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 2.0 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 7.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 5.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.0 | 3.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 3.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.8 | 2.5 | GO:0005055 | laminin receptor activity(GO:0005055) |
0.0 | 2.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 2.4 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 2.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.1 | 2.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.2 | 1.9 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 6.6 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 3.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.0 | 2.3 | PID NECTIN PATHWAY | Nectin adhesion pathway |
0.0 | 2.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 2.0 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
0.0 | 1.8 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
0.0 | 1.4 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 1.0 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 1.0 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
0.0 | 0.8 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 6.5 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
0.0 | 6.4 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
0.1 | 2.9 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 2.6 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 2.6 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
0.0 | 2.5 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.1 | 1.4 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 1.4 | REACTOME AMYLOIDS | Genes involved in Amyloids |
0.0 | 1.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 1.1 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |