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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GZF1

Z-value: 0.29

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
GZF1
ENSG00000125812.16 GDNF inducible zinc finger protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GZF1hg38_v1_chr20_+_23362144_233623200.147.5e-01Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_33080445 0.23 ENST00000428835.5
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr3_-_86991135 0.16 ENST00000398399.7
VGLL3
vestigial like family member 3
chr1_+_78649818 0.15 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr1_+_148889403 0.14 ENST00000464103.5
ENST00000534536.5
ENST00000369356.8
ENST00000369354.7
ENST00000369347.8
ENST00000369349.7
ENST00000369351.7
PDE4DIP
phosphodiesterase 4D interacting protein
chr7_-_27143672 0.14 ENST00000222726.4
HOXA5
homeobox A5
chr14_-_52069039 0.14 ENST00000216286.10
NID2
nidogen 2
chr14_-_52069228 0.13 ENST00000617139.4
NID2
nidogen 2
chr6_-_33080710 0.12 ENST00000419277.5
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chrX_+_54809060 0.11 ENST00000396224.1
MAGED2
MAGE family member D2
chr1_+_26280117 0.10 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamate rich protein like 3
chr19_-_43880142 0.10 ENST00000324394.7
ZNF404
zinc finger protein 404
chr1_+_26280059 0.09 ENST00000270792.10
SH3BGRL3
SH3 domain binding glutamate rich protein like 3
chrX_+_81202066 0.09 ENST00000373212.6
SH3BGRL
SH3 domain binding glutamate rich protein like
chr19_-_36054224 0.08 ENST00000292894.2
THAP8
THAP domain containing 8
chrX_+_103628692 0.08 ENST00000372626.7
TCEAL1
transcription elongation factor A like 1
chr11_-_17476801 0.06 ENST00000644772.1
ENST00000642271.1
ENST00000684571.1
ENST00000646902.1
ENST00000647015.1
ENST00000302539.9
ENST00000389817.8
ENST00000643260.1
ENST00000683136.1
ABCC8
ATP binding cassette subfamily C member 8
chr19_+_12995467 0.06 ENST00000592199.6
NFIX
nuclear factor I X
chr6_+_30557274 0.06 ENST00000376557.3
PRR3
proline rich 3
chr6_+_30557287 0.05 ENST00000376560.8
PRR3
proline rich 3
chr4_+_26343156 0.05 ENST00000680928.1
ENST00000681260.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr16_+_86578543 0.05 ENST00000320241.5
FOXL1
forkhead box L1
chr16_-_1611985 0.05 ENST00000426508.7
IFT140
intraflagellar transport 140
chr7_-_26864573 0.04 ENST00000345317.7
SKAP2
src kinase associated phosphoprotein 2
chr19_+_926001 0.04 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr12_+_106774630 0.04 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8B
RIC8 guanine nucleotide exchange factor B
chr11_+_65572349 0.04 ENST00000316409.2
ENST00000449319.2
ENST00000530349.2
FAM89B
family with sequence similarity 89 member B
chr12_+_104064520 0.04 ENST00000229330.9
HCFC2
host cell factor C2
chrX_+_153972729 0.03 ENST00000369982.5
TMEM187
transmembrane protein 187
chr19_-_51630401 0.03 ENST00000683636.1
SIGLEC5
sialic acid binding Ig like lectin 5
chr6_-_36547400 0.03 ENST00000229812.8
STK38
serine/threonine kinase 38
chr17_-_38748184 0.03 ENST00000618941.4
ENST00000620225.5
ENST00000618506.1
ENST00000616129.4
PCGF2
polycomb group ring finger 2
chr1_-_41918666 0.02 ENST00000372584.5
HIVEP3
HIVEP zinc finger 3
chr14_-_59484006 0.02 ENST00000481608.1
L3HYPDH
trans-L-3-hydroxyproline dehydratase
chr14_-_59484317 0.02 ENST00000247194.9
L3HYPDH
trans-L-3-hydroxyproline dehydratase
chr1_-_41918858 0.02 ENST00000372583.6
HIVEP3
HIVEP zinc finger 3
chr3_+_10992175 0.02 ENST00000646702.1
SLC6A1
solute carrier family 6 member 1
chr19_+_38390055 0.02 ENST00000587947.5
ENST00000338502.8
SPRED3
sprouty related EVH1 domain containing 3
chr1_-_32336224 0.02 ENST00000329421.8
MARCKSL1
MARCKS like 1
chr19_-_51646800 0.02 ENST00000599649.5
ENST00000429354.3
ENST00000360844.6
SIGLEC5
SIGLEC14
sialic acid binding Ig like lectin 5
sialic acid binding Ig like lectin 14
chr19_-_58573555 0.02 ENST00000599369.5
MZF1
myeloid zinc finger 1
chr11_+_102047422 0.01 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
CFAP300
cilia and flagella associated protein 300
chr19_-_58573280 0.01 ENST00000594234.5
ENST00000596039.1
ENST00000215057.7
MZF1
myeloid zinc finger 1
chr20_-_32743406 0.01 ENST00000474815.2
ENST00000446419.6
ENST00000278980.11
ENST00000642484.1
ENST00000646357.1
COMMD7
ENSG00000285382.1
COMM domain containing 7
novel protein
chr9_+_134326435 0.01 ENST00000481739.2
RXRA
retinoid X receptor alpha
chr1_-_226186673 0.01 ENST00000366812.6
ACBD3
acyl-CoA binding domain containing 3
chr9_-_14307928 0.01 ENST00000637640.1
ENST00000493697.1
ENST00000636057.1
NFIB
nuclear factor I B
chr7_+_5045821 0.01 ENST00000353796.7
ENST00000396912.2
ENST00000396904.2
RBAK
RBAK-RBAKDN
RB associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr22_-_42959852 0.01 ENST00000402229.5
ENST00000407585.5
ENST00000453079.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr16_+_67842277 0.01 ENST00000303596.3
THAP11
THAP domain containing 11
chr1_-_2530256 0.01 ENST00000378453.4
HES5
hes family bHLH transcription factor 5
chr9_+_128371343 0.01 ENST00000372850.5
ENST00000372847.1
ENST00000372853.9
ENST00000483206.2
URM1
ubiquitin related modifier 1
chr2_-_149587602 0.01 ENST00000428879.5
ENST00000303319.10
ENST00000422782.2
MMADHC
metabolism of cobalamin associated D
chr1_-_120051714 0.00 ENST00000579475.7
NOTCH2
notch receptor 2
chr7_-_6706843 0.00 ENST00000394917.3
ENST00000342651.9
ENST00000405858.6
ZNF12
zinc finger protein 12
chr19_-_10315987 0.00 ENST00000393708.3
ENST00000494368.5
FDX2
ferredoxin 2
chr1_+_40709475 0.00 ENST00000372651.5
NFYC
nuclear transcription factor Y subunit gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:1905073 positive regulation of relaxation of muscle(GO:1901079) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.0 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse