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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HMGA1

Z-value: 0.66

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Transcription factors associated with HMGA1

Gene Symbol Gene ID Gene Info
HMGA1
ENSG00000137309.20 high mobility group AT-hook 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA1hg38_v1_chr6_+_34236865_34236887-0.285.0e-01Click!

Activity profile of HMGA1 motif

Sorted Z-values of HMGA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_224947030 0.93 ENST00000409592.7
DOCK10
dedicator of cytokinesis 10
chr5_+_93583212 0.81 ENST00000327111.8
NR2F1
nuclear receptor subfamily 2 group F member 1
chr12_-_91146195 0.79 ENST00000548218.1
DCN
decorin
chr9_-_41908681 0.59 ENST00000476961.5
CNTNAP3B
contactin associated protein family member 3B
chr12_-_91153149 0.57 ENST00000550758.1
DCN
decorin
chr2_+_188974364 0.56 ENST00000304636.9
ENST00000317840.9
COL3A1
collagen type III alpha 1 chain
chr9_-_92424427 0.53 ENST00000375550.5
OMD
osteomodulin
chr2_-_162242998 0.48 ENST00000627638.2
ENST00000447386.5
FAP
fibroblast activation protein alpha
chr8_-_121641424 0.47 ENST00000303924.5
HAS2
hyaluronan synthase 2
chr18_-_28036585 0.46 ENST00000399380.7
CDH2
cadherin 2
chr12_-_91180365 0.45 ENST00000547937.5
DCN
decorin
chr12_-_91179472 0.43 ENST00000550099.5
ENST00000546391.5
DCN
decorin
chr13_+_75804169 0.42 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr1_-_56579555 0.41 ENST00000371250.4
PLPP3
phospholipid phosphatase 3
chr4_-_137532452 0.36 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr4_-_155866277 0.35 ENST00000537611.3
ASIC5
acid sensing ion channel subunit family member 5
chr14_-_91946989 0.34 ENST00000556154.5
FBLN5
fibulin 5
chrX_-_143635081 0.33 ENST00000338017.8
SLITRK4
SLIT and NTRK like family member 4
chr4_+_87832917 0.32 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr22_-_28306645 0.32 ENST00000612946.4
TTC28
tetratricopeptide repeat domain 28
chr7_+_117014881 0.31 ENST00000422922.5
ENST00000432298.5
ST7
suppression of tumorigenicity 7
chr1_+_163068775 0.31 ENST00000421743.6
RGS4
regulator of G protein signaling 4
chr13_-_37598750 0.30 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
POSTN
periostin
chr7_-_138701352 0.28 ENST00000421622.5
ENST00000674285.1
SVOPL
SVOP like
chr8_-_81483226 0.28 ENST00000256104.5
FABP4
fatty acid binding protein 4
chr9_-_39288138 0.27 ENST00000297668.10
CNTNAP3
contactin associated protein family member 3
chr13_+_75804221 0.26 ENST00000489941.6
ENST00000525373.5
LMO7
LIM domain 7
chr12_+_59596010 0.26 ENST00000547379.6
ENST00000552432.5
SLC16A7
solute carrier family 16 member 7
chr17_-_31314040 0.26 ENST00000330927.5
EVI2B
ecotropic viral integration site 2B
chr1_+_77918128 0.26 ENST00000342754.5
NEXN
nexilin F-actin binding protein
chr6_-_46325641 0.26 ENST00000330430.10
ENST00000405162.2
RCAN2
regulator of calcineurin 2
chr13_-_67230313 0.25 ENST00000377865.7
PCDH9
protocadherin 9
chr17_-_31314066 0.25 ENST00000577894.1
EVI2B
ecotropic viral integration site 2B
chr8_-_23854796 0.24 ENST00000290271.7
STC1
stanniocalcin 1
chr6_-_117425855 0.24 ENST00000368508.7
ROS1
ROS proto-oncogene 1, receptor tyrosine kinase
chr9_+_87497222 0.24 ENST00000358077.9
DAPK1
death associated protein kinase 1
chr22_-_33572227 0.24 ENST00000674780.1
LARGE1
LARGE xylosyl- and glucuronyltransferase 1
chr13_+_31945826 0.24 ENST00000647500.1
FRY
FRY microtubule binding protein
chr16_-_18876305 0.23 ENST00000563235.5
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr5_+_141412979 0.23 ENST00000612503.1
ENST00000398610.3
PCDHGA10
protocadherin gamma subfamily A, 10
chr7_+_94394886 0.22 ENST00000297268.11
ENST00000620463.1
COL1A2
collagen type I alpha 2 chain
chr6_-_117425905 0.22 ENST00000368507.8
ROS1
ROS proto-oncogene 1, receptor tyrosine kinase
chr2_+_209580024 0.22 ENST00000392194.5
MAP2
microtubule associated protein 2
chr13_-_67230377 0.22 ENST00000544246.5
ENST00000377861.4
PCDH9
protocadherin 9
chr3_+_99638475 0.22 ENST00000452013.5
ENST00000261037.7
ENST00000652472.1
ENST00000273342.8
ENST00000621757.1
COL8A1
collagen type VIII alpha 1 chain
chr2_+_151357583 0.21 ENST00000243347.5
TNFAIP6
TNF alpha induced protein 6
chr4_-_76007501 0.21 ENST00000264888.6
CXCL9
C-X-C motif chemokine ligand 9
chr7_+_93921720 0.21 ENST00000248564.6
GNG11
G protein subunit gamma 11
chr21_-_26843063 0.21 ENST00000678221.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843012 0.21 ENST00000517777.6
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr12_-_71157872 0.21 ENST00000546561.2
TSPAN8
tetraspanin 8
chr13_+_112979306 0.21 ENST00000421756.5
MCF2L
MCF.2 cell line derived transforming sequence like
chr9_-_39239174 0.20 ENST00000358144.6
CNTNAP3
contactin associated protein family member 3
chrX_+_86714623 0.20 ENST00000484479.1
DACH2
dachshund family transcription factor 2
chr3_+_73061659 0.20 ENST00000533473.1
EBLN2
endogenous Bornavirus like nucleoprotein 2
chr14_+_50560137 0.20 ENST00000358385.12
ATL1
atlastin GTPase 1
chr14_+_32329256 0.20 ENST00000280979.9
AKAP6
A-kinase anchoring protein 6
chrX_+_10158448 0.20 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
CLCN4
chloride voltage-gated channel 4
chr4_+_122339221 0.19 ENST00000442707.1
KIAA1109
KIAA1109
chr10_-_77140757 0.19 ENST00000637862.2
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr5_+_137867852 0.19 ENST00000421631.6
ENST00000239926.9
MYOT
myotilin
chr5_-_88785493 0.18 ENST00000503554.4
MEF2C
myocyte enhancer factor 2C
chr12_+_59689337 0.18 ENST00000261187.8
SLC16A7
solute carrier family 16 member 7
chr11_-_55936400 0.18 ENST00000301532.3
OR5I1
olfactory receptor family 5 subfamily I member 1
chr5_+_141223332 0.18 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
PCDHB14
ENSG00000279983.1
protocadherin beta 14
novel protein
chr3_+_141384790 0.18 ENST00000507722.5
ZBTB38
zinc finger and BTB domain containing 38
chr12_+_78864768 0.18 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr14_-_59630582 0.17 ENST00000395090.5
RTN1
reticulon 1
chr2_-_98663464 0.17 ENST00000414521.6
MGAT4A
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr5_-_88731827 0.17 ENST00000627170.2
MEF2C
myocyte enhancer factor 2C
chr5_+_179023794 0.16 ENST00000519896.5
ENST00000522442.1
ENST00000444149.7
ZNF879
zinc finger protein 879
chr1_+_103750406 0.16 ENST00000370079.3
AMY1C
amylase alpha 1C
chr5_-_111758061 0.16 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
NREP
neuronal regeneration related protein
chr12_-_71157992 0.16 ENST00000247829.8
TSPAN8
tetraspanin 8
chr6_+_151325665 0.16 ENST00000354675.10
AKAP12
A-kinase anchoring protein 12
chr9_-_42129125 0.16 ENST00000617422.4
ENST00000612828.4
ENST00000341990.8
ENST00000377561.7
ENST00000276974.7
CNTNAP3B
contactin associated protein family member 3B
chr3_-_112641292 0.16 ENST00000439685.6
CCDC80
coiled-coil domain containing 80
chr16_-_3372666 0.16 ENST00000399974.5
MTRNR2L4
MT-RNR2 like 4
chr7_-_93890160 0.16 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr8_+_38728550 0.15 ENST00000520340.5
ENST00000518415.5
TACC1
transforming acidic coiled-coil containing protein 1
chr3_+_130931893 0.15 ENST00000504612.5
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr6_+_101181254 0.15 ENST00000682090.1
ENST00000421544.6
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr12_-_122395422 0.15 ENST00000540304.6
CLIP1
CAP-Gly domain containing linker protein 1
chr7_-_108240049 0.15 ENST00000379022.8
NRCAM
neuronal cell adhesion molecule
chr2_-_213151590 0.15 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKZF2
IKAROS family zinc finger 2
chr7_+_134745460 0.15 ENST00000436461.6
CALD1
caldesmon 1
chr11_+_5389377 0.14 ENST00000328611.5
OR51M1
olfactory receptor family 51 subfamily M member 1
chr1_+_178341445 0.14 ENST00000462775.5
RASAL2
RAS protein activator like 2
chr8_+_95024977 0.14 ENST00000396124.9
NDUFAF6
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr2_+_178451598 0.14 ENST00000644554.1
ENST00000647226.1
PJVK
pejvakin
chr6_-_29375291 0.14 ENST00000396806.3
OR12D3
olfactory receptor family 12 subfamily D member 3
chr14_+_94612383 0.14 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
SERPINA3
serpin family A member 3
chr17_-_65826445 0.14 ENST00000317442.12
CEP112
centrosomal protein 112
chr15_-_84654270 0.14 ENST00000434634.7
WDR73
WD repeat domain 73
chr4_+_54229261 0.14 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
PDGFRA
platelet derived growth factor receptor alpha
chr5_+_141421064 0.13 ENST00000518882.2
PCDHGA11
protocadherin gamma subfamily A, 11
chr3_-_195583931 0.13 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
APOD
apolipoprotein D
chr5_-_88877967 0.13 ENST00000508610.5
ENST00000636294.1
MEF2C
myocyte enhancer factor 2C
chr17_-_66220630 0.13 ENST00000585162.1
APOH
apolipoprotein H
chr7_-_137846860 0.13 ENST00000288490.9
ENST00000614521.2
ENST00000424189.6
ENST00000446122.5
DGKI
diacylglycerol kinase iota
chr7_+_92057602 0.13 ENST00000491695.2
AKAP9
A-kinase anchoring protein 9
chr12_+_32502114 0.13 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_179882275 0.13 ENST00000606911.7
ENST00000271583.7
TOR1AIP1
torsin 1A interacting protein 1
chr19_-_9538590 0.12 ENST00000593003.5
ZNF426
zinc finger protein 426
chr1_+_174875505 0.12 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr3_+_69763549 0.12 ENST00000472437.5
MITF
melanocyte inducing transcription factor
chrX_+_22272913 0.12 ENST00000323684.4
CBLL2
Cbl proto-oncogene like 2
chr13_+_32031706 0.12 ENST00000542859.6
FRY
FRY microtubule binding protein
chr16_+_53207981 0.12 ENST00000565803.2
CHD9
chromodomain helicase DNA binding protein 9
chr9_-_21482313 0.12 ENST00000448696.4
IFNE
interferon epsilon
chr10_-_104338431 0.11 ENST00000647721.1
ENST00000337478.3
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr4_+_141636563 0.11 ENST00000320650.9
ENST00000296545.11
IL15
interleukin 15
chr12_+_12891554 0.11 ENST00000014914.6
GPRC5A
G protein-coupled receptor class C group 5 member A
chr14_+_73097027 0.11 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr17_-_41382298 0.11 ENST00000394001.3
KRT34
keratin 34
chr8_+_73991345 0.11 ENST00000284818.7
ENST00000518893.1
LY96
lymphocyte antigen 96
chr16_-_18868218 0.11 ENST00000566328.2
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr1_+_159439722 0.11 ENST00000641630.1
ENST00000423932.6
OR10J1
olfactory receptor family 10 subfamily J member 1
chr3_-_149377637 0.11 ENST00000305366.8
TM4SF1
transmembrane 4 L six family member 1
chr2_+_209653171 0.11 ENST00000447185.5
MAP2
microtubule associated protein 2
chr5_+_141355003 0.11 ENST00000571252.3
ENST00000612927.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr4_-_176195563 0.11 ENST00000280191.7
SPATA4
spermatogenesis associated 4
chr1_-_146144804 0.11 ENST00000583866.9
ENST00000617010.2
NBPF10
NBPF member 10
chr11_-_7796942 0.11 ENST00000329434.3
OR5P2
olfactory receptor family 5 subfamily P member 2
chr9_+_94084458 0.11 ENST00000620992.5
ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr3_+_101827982 0.11 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr2_-_181680490 0.11 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
CERKL
NEUROD1
ceramide kinase like
neuronal differentiation 1
chr1_+_103617427 0.11 ENST00000423678.2
ENST00000414303.7
AMY2A
amylase alpha 2A
chrX_+_103776493 0.11 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
PLP1
proteolipid protein 1
chr12_+_55362975 0.11 ENST00000641576.1
OR6C75
olfactory receptor family 6 subfamily C member 75
chr1_-_86383078 0.11 ENST00000460698.6
ODF2L
outer dense fiber of sperm tails 2 like
chr1_+_12464912 0.11 ENST00000543766.2
VPS13D
vacuolar protein sorting 13 homolog D
chrX_-_40177213 0.11 ENST00000672922.2
ENST00000378455.8
ENST00000342274.8
BCOR
BCL6 corepressor
chr11_-_63144221 0.11 ENST00000417740.5
ENST00000612278.4
ENST00000326192.5
SLC22A24
solute carrier family 22 member 24
chr3_-_71493500 0.10 ENST00000648380.1
ENST00000650295.1
FOXP1
forkhead box P1
chr14_-_72894091 0.10 ENST00000556509.6
DPF3
double PHD fingers 3
chr6_-_116254063 0.10 ENST00000420283.3
TSPYL4
TSPY like 4
chr22_-_30246739 0.10 ENST00000403987.3
ENST00000249075.4
LIF
LIF interleukin 6 family cytokine
chr12_-_10998304 0.10 ENST00000538986.2
TAS2R20
taste 2 receptor member 20
chr5_+_141150012 0.10 ENST00000231136.4
ENST00000622991.1
PCDHB6
protocadherin beta 6
chr5_+_119629552 0.10 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
FAM170A
family with sequence similarity 170 member A
chr17_-_55722857 0.10 ENST00000424486.3
TMEM100
transmembrane protein 100
chr7_+_107583919 0.10 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr11_+_113908983 0.10 ENST00000537778.5
HTR3B
5-hydroxytryptamine receptor 3B
chr3_-_179251615 0.10 ENST00000314235.9
ENST00000392685.6
KCNMB3
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr3_+_141387801 0.10 ENST00000514251.5
ZBTB38
zinc finger and BTB domain containing 38
chr4_+_141636611 0.10 ENST00000514653.5
IL15
interleukin 15
chrX_-_13817346 0.10 ENST00000356942.9
GPM6B
glycoprotein M6B
chr4_-_82844418 0.10 ENST00000503937.5
SEC31A
SEC31 homolog A, COPII coat complex component
chr4_+_141636923 0.10 ENST00000529613.5
IL15
interleukin 15
chr4_-_82848843 0.10 ENST00000511338.1
SEC31A
SEC31 homolog A, COPII coat complex component
chr12_-_11134644 0.10 ENST00000539585.1
TAS2R30
taste 2 receptor member 30
chr1_+_179882040 0.10 ENST00000528443.6
TOR1AIP1
torsin 1A interacting protein 1
chr14_-_106062670 0.10 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr1_+_205042960 0.10 ENST00000638378.1
CNTN2
contactin 2
chr5_-_139198358 0.10 ENST00000394817.7
SIL1
SIL1 nucleotide exchange factor
chr14_-_106470788 0.10 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr6_-_26108125 0.10 ENST00000338379.6
H1-6
H1.6 linker histone, cluster member
chr12_+_21527017 0.10 ENST00000535033.5
SPX
spexin hormone
chr10_+_17951825 0.09 ENST00000539911.5
SLC39A12
solute carrier family 39 member 12
chr5_+_176448363 0.09 ENST00000261942.7
FAF2
Fas associated factor family member 2
chr10_+_17951885 0.09 ENST00000377374.8
SLC39A12
solute carrier family 39 member 12
chr2_+_148978361 0.09 ENST00000678720.1
ENST00000678856.1
ENST00000677080.1
KIF5C
kinesin family member 5C
chr10_+_17951906 0.09 ENST00000377371.3
ENST00000377369.7
SLC39A12
solute carrier family 39 member 12
chr5_-_88823763 0.09 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
MEF2C
myocyte enhancer factor 2C
chr12_+_55549602 0.09 ENST00000641569.1
ENST00000641851.1
OR6C4
olfactory receptor family 6 subfamily C member 4
chr18_+_34710307 0.09 ENST00000679796.1
DTNA
dystrobrevin alpha
chr12_-_110920568 0.09 ENST00000548438.1
ENST00000228841.15
MYL2
myosin light chain 2
chr7_+_150567382 0.09 ENST00000255945.4
ENST00000479232.1
GIMAP4
GTPase, IMAP family member 4
chr4_-_73988179 0.09 ENST00000296028.4
PPBP
pro-platelet basic protein
chr20_-_56525925 0.09 ENST00000243913.8
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr6_+_12717660 0.09 ENST00000674637.1
PHACTR1
phosphatase and actin regulator 1
chr16_-_71724700 0.09 ENST00000568954.5
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr7_-_80512041 0.09 ENST00000398291.4
GNAT3
G protein subunit alpha transducin 3
chrX_+_80420466 0.09 ENST00000308293.5
TENT5D
terminal nucleotidyltransferase 5D
chrX_-_100732100 0.09 ENST00000372981.1
ENST00000263033.9
SYTL4
synaptotagmin like 4
chr4_-_99352754 0.09 ENST00000639454.1
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr9_-_115091018 0.09 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
TNC
tenascin C
chr8_-_107498041 0.09 ENST00000297450.7
ANGPT1
angiopoietin 1
chr10_-_103153609 0.09 ENST00000675985.1
NT5C2
5'-nucleotidase, cytosolic II
chr17_-_31321603 0.09 ENST00000462804.3
EVI2A
ecotropic viral integration site 2A
chr20_-_13990609 0.09 ENST00000284951.10
ENST00000378072.5
SEL1L2
SEL1L2 adaptor subunit of ERAD E3 ligase
chr3_+_108822778 0.09 ENST00000295756.11
TRAT1
T cell receptor associated transmembrane adaptor 1
chr3_+_69866217 0.09 ENST00000314589.10
MITF
melanocyte inducing transcription factor
chrX_-_101617921 0.08 ENST00000361910.9
ENST00000538627.5
ENST00000539247.5
ARMCX6
armadillo repeat containing X-linked 6
chr11_+_54706832 0.08 ENST00000319760.8
OR4A5
olfactory receptor family 4 subfamily A member 5
chrX_-_77634229 0.08 ENST00000675732.1
ATRX
ATRX chromatin remodeler
chr7_+_117020191 0.08 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
ST7
suppression of tumorigenicity 7
chr11_+_93746433 0.08 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr7_-_138002017 0.08 ENST00000452463.5
ENST00000456390.5
ENST00000330387.11
CREB3L2
cAMP responsive element binding protein 3 like 2
chr17_-_69141878 0.08 ENST00000590645.1
ENST00000284425.7
ABCA6
ATP binding cassette subfamily A member 6
chr2_+_108588286 0.08 ENST00000332345.10
LIMS1
LIM zinc finger domain containing 1
chr3_+_108822759 0.08 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr19_+_926001 0.08 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr2_+_232633551 0.08 ENST00000264059.8
EFHD1
EF-hand domain family member D1
chr7_+_20647388 0.08 ENST00000258738.10
ABCB5
ATP binding cassette subfamily B member 5
chr8_-_132625378 0.08 ENST00000522789.5
LRRC6
leucine rich repeat containing 6
chr9_+_128340474 0.08 ENST00000300456.5
SLC27A4
solute carrier family 27 member 4
chr21_+_25639272 0.08 ENST00000400532.5
ENST00000312957.9
JAM2
junctional adhesion molecule 2
chr4_-_39032343 0.08 ENST00000381938.4
TMEM156
transmembrane protein 156

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.5 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.6 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.0 0.1 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0048058 compound eye corneal lens development(GO:0048058)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.0 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.0 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.3 GO:0070168 negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)
0.0 0.1 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.0 GO:0060018 astrocyte fate commitment(GO:0060018)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0071920 cleavage body(GO:0071920)
0.0 0.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.0 GO:0071756 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113) interleukin-18 receptor activity(GO:0042008)
0.0 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.0 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels