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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HMX1

Z-value: 0.74

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Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
ENSG00000215612.8 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX1hg38_v1_chr4_-_8871817_88718570.059.0e-01Click!

Activity profile of HMX1 motif

Sorted Z-values of HMX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_183636065 0.83 ENST00000304685.8
ral guanine nucleotide dissociation stimulator like 1
chr15_+_32718476 0.82 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr15_+_32717994 0.79 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr5_-_81751085 0.74 ENST00000515395.5
single stranded DNA binding protein 2
chr5_-_81751022 0.71 ENST00000509013.2
ENST00000505980.5
ENST00000509053.5
single stranded DNA binding protein 2
chr12_+_53046969 0.69 ENST00000379902.7
tensin 2
chr2_-_174597795 0.63 ENST00000679041.1
WAS/WASL interacting protein family member 1
chr5_-_81751103 0.62 ENST00000514493.5
ENST00000320672.8
ENST00000615665.4
single stranded DNA binding protein 2
chr5_+_157266079 0.62 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
cytoplasmic FMR1 interacting protein 2
chr3_+_69739425 0.57 ENST00000352241.9
ENST00000642352.1
melanocyte inducing transcription factor
chr16_-_73048104 0.55 ENST00000268489.10
zinc finger homeobox 3
chr19_-_1401487 0.53 ENST00000640762.1
ENST00000252288.8
ENST00000447102.8
guanidinoacetate N-methyltransferase
chr12_-_55688891 0.53 ENST00000557555.2
integrin subunit alpha 7
chrX_-_107775951 0.51 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22 domain family member 3
chr12_-_15221394 0.48 ENST00000537647.5
ENST00000256953.6
ENST00000546331.5
RAS like estrogen regulated growth inhibitor
chr5_-_9546066 0.47 ENST00000382496.10
ENST00000652226.1
semaphorin 5A
chr1_-_46132616 0.44 ENST00000423209.5
ENST00000262741.10
phosphoinositide-3-kinase regulatory subunit 3
chr8_+_119416427 0.44 ENST00000259526.4
cellular communication network factor 3
chr1_-_46132650 0.41 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr1_-_25906457 0.40 ENST00000426559.6
stathmin 1
chr16_+_12901757 0.40 ENST00000423335.2
shisa family member 9
chr16_+_15434577 0.39 ENST00000300006.9
bMERB domain containing 1
chr16_+_15434475 0.38 ENST00000566490.5
bMERB domain containing 1
chr11_-_65872728 0.38 ENST00000528176.5
ENST00000307998.11
EGF containing fibulin extracellular matrix protein 2
chr1_-_32702736 0.37 ENST00000373484.4
ENST00000409190.8
syncoilin, intermediate filament protein
chr12_+_32399517 0.36 ENST00000534526.7
FYVE, RhoGEF and PH domain containing 4
chr3_+_152268920 0.35 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
muscleblind like splicing regulator 1
chr10_+_134465 0.34 ENST00000439456.5
ENST00000397962.8
ENST00000309776.8
ENST00000397959.7
zinc finger MYND-type containing 11
chr7_-_132576463 0.34 ENST00000423507.6
plexin A4
chr2_-_179264757 0.32 ENST00000428443.8
SEC14 and spectrin domain containing 1
chr2_+_74549026 0.32 ENST00000409429.5
docking protein 1
chr2_-_174598206 0.32 ENST00000392546.6
ENST00000436221.1
WAS/WASL interacting protein family member 1
chr17_-_7043906 0.32 ENST00000308009.5
ENST00000447225.1
solute carrier family 16 member 11
chr17_-_7044091 0.31 ENST00000574600.3
ENST00000662352.3
ENST00000673828.2
solute carrier family 16 member 11
chr1_-_201507116 0.31 ENST00000340006.7
ENST00000526256.5
ENST00000526723.5
ENST00000524951.5
cysteine and glycine rich protein 1
chrX_+_22032301 0.31 ENST00000379374.5
phosphate regulating endopeptidase homolog X-linked
chr12_-_15882261 0.30 ENST00000646918.1
ENST00000647087.1
ENST00000535752.5
epidermal growth factor receptor pathway substrate 8
chr9_+_122510802 0.30 ENST00000335302.5
olfactory receptor family 1 subfamily J member 2
chr17_+_82032182 0.28 ENST00000584341.1
Rac family small GTPase 3
chr20_+_58888779 0.28 ENST00000488546.6
ENST00000667293.2
ENST00000481039.6
ENST00000467321.6
GNAS complex locus
chr17_+_82031643 0.28 ENST00000306897.9
Rac family small GTPase 3
chr10_+_97498881 0.28 ENST00000370664.4
ubiquitin domain containing 1
chr6_-_56851888 0.28 ENST00000312431.10
ENST00000520645.5
dystonin
chr14_-_100568070 0.27 ENST00000557378.6
ENST00000443071.6
ENST00000637646.1
brain enriched guanylate kinase associated
chr11_-_417304 0.27 ENST00000397632.7
single Ig and TIR domain containing
chr11_-_106022209 0.27 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr8_+_38996848 0.27 ENST00000466936.5
ADAM metallopeptidase domain 9
chr9_+_88388356 0.27 ENST00000375859.4
spindlin 1
chr14_+_105314711 0.26 ENST00000447393.6
ENST00000547217.5
phosphofurin acidic cluster sorting protein 2
chr22_+_37051731 0.26 ENST00000610767.4
ENST00000402077.7
ENST00000403888.7
potassium channel tetramerization domain containing 17
chr17_+_82032061 0.26 ENST00000580965.5
Rac family small GTPase 3
chr13_+_41457543 0.26 ENST00000379359.4
regulator of cell cycle
chr1_-_167090370 0.25 ENST00000367868.4
glycoprotein A33
chr11_-_106077401 0.25 ENST00000526793.5
kelch repeat and BTB domain containing 3
chr22_+_37051787 0.25 ENST00000456470.1
potassium channel tetramerization domain containing 17
chr2_-_166375969 0.24 ENST00000454569.6
ENST00000409672.5
sodium voltage-gated channel alpha subunit 9
chr2_+_30231524 0.23 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr12_+_57089094 0.23 ENST00000342556.6
ENST00000300131.8
NGFI-A binding protein 2
chr2_-_27323006 0.23 ENST00000402310.5
ENST00000405983.5
ENST00000403262.6
mitochondrial inner membrane protein MPV17
chr2_-_166375901 0.23 ENST00000303354.11
ENST00000645907.1
ENST00000642356.2
ENST00000452182.2
sodium voltage-gated channel alpha subunit 9
chr6_+_16238554 0.23 ENST00000259727.5
guanosine monophosphate reductase
chr2_+_24491239 0.23 ENST00000348332.8
nuclear receptor coactivator 1
chr17_-_74972714 0.23 ENST00000530857.1
HID1 domain containing
chr4_-_141133436 0.23 ENST00000306799.7
ENST00000515673.7
ring finger protein 150
chr17_-_15341577 0.22 ENST00000543896.1
ENST00000395930.6
ENST00000539245.5
ENST00000539316.1
tektin 3
chr2_+_106065678 0.22 ENST00000238044.8
ENST00000437659.1
ECRG4 augurin precursor
chr20_+_32359237 0.22 ENST00000643168.1
ASXL transcriptional regulator 1
chr22_-_31345770 0.22 ENST00000215919.3
POZ/BTB and AT hook containing zinc finger 1
chr17_+_68512878 0.22 ENST00000585981.5
ENST00000589480.5
ENST00000585815.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr1_-_53940100 0.21 ENST00000371376.1
heat shock protein family B (small) member 11
chr7_-_132576493 0.21 ENST00000321063.8
plexin A4
chr2_+_24491860 0.21 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr17_-_75271205 0.21 ENST00000649805.1
MIF4G domain containing
chr14_-_24081986 0.20 ENST00000560550.1
neural retina leucine zipper
chr13_-_96994730 0.20 ENST00000541518.6
oxoglutarate receptor 1
chr16_+_12901591 0.20 ENST00000558583.3
shisa family member 9
chr13_-_96994350 0.20 ENST00000298440.5
ENST00000543457.6
ENST00000541038.2
oxoglutarate receptor 1
chr17_+_68512379 0.20 ENST00000392711.5
ENST00000585427.5
ENST00000589228.6
ENST00000536854.6
ENST00000588702.5
ENST00000589309.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr1_+_150549734 0.20 ENST00000674043.1
ENST00000674058.1
ADAMTS like 4
chr11_+_131911396 0.20 ENST00000425719.6
ENST00000374784.5
neurotrimin
chr11_-_106077313 0.20 ENST00000531837.2
ENST00000534815.1
kelch repeat and BTB domain containing 3
chr20_-_21514046 0.20 ENST00000377142.5
NK2 homeobox 2
chr1_-_25906411 0.20 ENST00000455785.7
stathmin 1
chr11_+_118607598 0.19 ENST00000600882.6
ENST00000356063.9
pleckstrin homology like domain family B member 1
chr2_-_219571529 0.19 ENST00000404537.6
obscurin like cytoskeletal adaptor 1
chr19_+_54105923 0.19 ENST00000420296.1
NADH:ubiquinone oxidoreductase subunit A3
chr2_-_174597728 0.19 ENST00000409891.5
ENST00000410117.5
WAS/WASL interacting protein family member 1
chr5_-_59039454 0.19 ENST00000358923.10
phosphodiesterase 4D
chr20_+_58889143 0.19 ENST00000470512.6
ENST00000464788.6
ENST00000469431.6
ENST00000478585.6
ENST00000604005.6
GNAS complex locus
chr6_+_36676455 0.18 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr5_+_139648338 0.18 ENST00000302517.8
CXXC finger protein 5
chr20_+_58889100 0.18 ENST00000477931.5
ENST00000485673.6
GNAS complex locus
chr12_+_53295506 0.18 ENST00000549759.2
ENST00000628881.2
ENST00000351500.7
ENST00000550846.5
ENST00000334478.9
ENST00000547130.6
ENST00000552742.6
prefoldin subunit 5
chr20_-_36746053 0.18 ENST00000373803.6
ENST00000359675.6
ENST00000349004.6
NDRG family member 3
chr20_+_32358979 0.18 ENST00000646985.1
ENST00000497249.6
ASXL transcriptional regulator 1
chr9_-_120877026 0.17 ENST00000436309.5
PHD finger protein 19
chr11_-_417385 0.17 ENST00000332725.7
single Ig and TIR domain containing
chr2_-_27322564 0.17 ENST00000233545.6
mitochondrial inner membrane protein MPV17
chr1_+_150549384 0.17 ENST00000369041.9
ENST00000271643.9
ADAMTS like 4
chr17_-_75271223 0.17 ENST00000579297.5
ENST00000580571.5
ENST00000325102.13
MIF4G domain containing
chr8_-_26867267 0.17 ENST00000380573.4
adrenoceptor alpha 1A
chr11_+_117232625 0.17 ENST00000534428.5
ENST00000300650.9
ring finger protein 214
chr2_-_27323072 0.17 ENST00000428910.5
ENST00000402722.5
ENST00000380044.6
ENST00000399052.8
ENST00000405076.5
mitochondrial inner membrane protein MPV17
chr3_-_108222362 0.17 ENST00000492106.1
intraflagellar transport 57
chr17_-_75270999 0.17 ENST00000579194.6
ENST00000580717.5
ENST00000577542.5
ENST00000579612.5
ENST00000245551.9
ENST00000578305.5
MIF4G domain containing
chr11_-_65047861 0.17 ENST00000533842.5
ENST00000532802.5
ENST00000530139.2
ENST00000526516.5
N-acetylated alpha-linked acidic dipeptidase like 1
chr14_+_104724221 0.16 ENST00000330877.7
adenylosuccinate synthase 1
chr6_+_163414637 0.16 ENST00000453779.6
ENST00000275262.11
ENST00000392127.6
QKI, KH domain containing RNA binding
chr17_-_44220831 0.16 ENST00000527034.5
upstream binding transcription factor
chr22_-_31346143 0.16 ENST00000405309.7
ENST00000351933.8
POZ/BTB and AT hook containing zinc finger 1
chr2_-_232487820 0.16 ENST00000304546.6
endothelin converting enzyme like 1
chr7_+_44200960 0.16 ENST00000496112.5
ENST00000678359.1
ENST00000223369.3
ENST00000677090.1
YKT6 v-SNARE homolog
chr1_-_25905989 0.16 ENST00000399728.5
stathmin 1
chr9_+_135075422 0.16 ENST00000371799.8
ENST00000277415.15
olfactomedin 1
chr1_-_50960230 0.15 ENST00000396153.7
Fas associated factor 1
chr7_-_98252117 0.15 ENST00000420697.1
ENST00000415086.5
ENST00000447648.7
tectonin beta-propeller repeat containing 1
chr17_+_19378476 0.15 ENST00000395604.8
ENST00000482850.1
mitogen-activated protein kinase 7
chrX_-_72714181 0.15 ENST00000339490.7
ENST00000541944.5
ENST00000373539.3
phosphorylase kinase regulatory subunit alpha 1
chr10_+_135067 0.15 ENST00000381591.5
zinc finger MYND-type containing 11
chr20_+_58889168 0.15 ENST00000480975.5
ENST00000480232.6
ENST00000484504.5
GNAS complex locus
chr11_+_117232725 0.15 ENST00000531287.5
ENST00000531452.5
ring finger protein 214
chr2_+_130181662 0.15 ENST00000425361.5
ENST00000457492.5
mitotic spindle organizing protein 2B
chr17_-_80476597 0.14 ENST00000306773.5
neuronal pentraxin 1
chr9_-_127569011 0.14 ENST00000373312.4
niban apoptosis regulator 2
chr8_+_38996899 0.14 ENST00000677582.1
ENST00000676643.1
ENST00000676936.1
ENST00000677004.1
ENST00000487273.7
ENST00000481513.5
ADAM metallopeptidase domain 9
chr19_-_45782388 0.14 ENST00000458663.6
DM1 protein kinase
chr6_+_125956696 0.14 ENST00000229633.7
histidine triad nucleotide binding protein 3
chr1_-_183635659 0.14 ENST00000367534.5
ENST00000294742.6
actin related protein 2/3 complex subunit 5
chr2_+_61065863 0.14 ENST00000402291.6
KIAA1841
chr11_+_69641146 0.14 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr22_+_50343294 0.14 ENST00000359139.7
ENST00000395741.7
ENST00000612753.5
ENST00000395744.7
protein phosphatase 6 regulatory subunit 2
chr17_-_44220963 0.14 ENST00000343638.9
upstream binding transcription factor
chr20_-_63969890 0.14 ENST00000369888.6
zinc finger protein 512B
chr22_-_19431692 0.14 ENST00000340170.8
ENST00000263208.5
histone cell cycle regulator
chr14_+_22543179 0.14 ENST00000390534.1
T cell receptor alpha joining 3
chr8_+_38996766 0.14 ENST00000676765.1
ADAM metallopeptidase domain 9
chr14_-_24634160 0.14 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr11_-_33722710 0.13 ENST00000415002.7
ENST00000437761.6
ENST00000445143.6
CD59 molecule (CD59 blood group)
chr5_-_115816650 0.13 ENST00000250535.5
cysteine dioxygenase type 1
chr3_-_108222383 0.13 ENST00000264538.4
intraflagellar transport 57
chr9_+_19049385 0.13 ENST00000380527.3
Ras related GTP binding A
chr17_-_75270710 0.13 ENST00000581777.2
MIF4G domain containing
chr14_-_24634266 0.13 ENST00000382540.5
granzyme B
chr19_-_12957198 0.13 ENST00000316939.3
GADD45G interacting protein 1
chrX_+_111681650 0.13 ENST00000436609.5
ENST00000482742.5
ENST00000623189.1
ALG13 UDP-N-acetylglucosaminyltransferase subunit
chr1_-_31763866 0.13 ENST00000398547.5
adhesion G protein-coupled receptor B2
chr14_-_99480784 0.13 ENST00000329331.7
ENST00000436070.6
SET domain containing 3, actin histidine methyltransferase
chr17_-_8630749 0.13 ENST00000379980.8
ENST00000269243.8
myosin heavy chain 10
chr22_+_46762617 0.13 ENST00000380995.5
ENST00000337137.9
ENST00000407381.7
TBC1 domain family member 22A
chr8_-_66613208 0.13 ENST00000522677.8
MYB proto-oncogene like 1
chr1_-_31764333 0.12 ENST00000398542.5
ENST00000373658.8
adhesion G protein-coupled receptor B2
chrX_+_47585212 0.12 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr17_-_74972742 0.12 ENST00000425042.7
ENST00000581676.1
HID1 domain containing
chr17_-_8630713 0.12 ENST00000411957.1
ENST00000360416.8
myosin heavy chain 10
chr1_-_183635776 0.12 ENST00000359856.11
actin related protein 2/3 complex subunit 5
chr12_-_30695852 0.12 ENST00000256079.9
importin 8
chr1_+_235327344 0.12 ENST00000488594.5
geranylgeranyl diphosphate synthase 1
chr19_-_36054224 0.12 ENST00000292894.2
THAP domain containing 8
chr20_+_13995369 0.12 ENST00000217246.8
ENST00000684519.1
ENST00000642719.1
mono-ADP ribosylhydrolase 2
chr7_+_50304693 0.12 ENST00000331340.8
ENST00000413698.5
ENST00000612658.4
ENST00000359197.9
ENST00000349824.8
ENST00000343574.9
ENST00000357364.8
ENST00000440768.6
ENST00000346667.8
ENST00000615491.4
IKAROS family zinc finger 1
chr12_+_56007484 0.12 ENST00000262032.9
IKAROS family zinc finger 4
chr1_+_155308930 0.11 ENST00000465559.5
ENST00000612683.1
farnesyl diphosphate synthase
chr1_+_155308748 0.11 ENST00000611010.4
ENST00000447866.5
ENST00000368356.9
ENST00000467076.5
ENST00000491013.5
ENST00000356657.10
farnesyl diphosphate synthase
chr19_+_37594830 0.11 ENST00000589117.5
zinc finger protein 540
chrX_+_136497079 0.11 ENST00000535601.5
ENST00000448450.5
ENST00000425695.5
HIV-1 Tat specific factor 1
chr12_-_6700788 0.11 ENST00000320591.9
ENST00000534837.6
PILR alpha associated neural protein
chr1_+_42682954 0.11 ENST00000436427.1
Y-box binding protein 1
chr8_-_29263063 0.11 ENST00000524189.6
kinesin family member 13B
chr22_+_46762677 0.11 ENST00000355704.7
TBC1 domain family member 22A
chr20_-_3159844 0.11 ENST00000217173.7
ENST00000449731.1
ENST00000380266.4
U-box domain containing 5
FAST kinase domains 5
chrX_+_136497586 0.10 ENST00000218364.5
HIV-1 Tat specific factor 1
chr1_-_114716729 0.10 ENST00000369535.5
NRAS proto-oncogene, GTPase
chr2_-_27489716 0.10 ENST00000260570.8
ENST00000675690.1
intraflagellar transport 172
chr11_-_33722403 0.10 ENST00000534312.5
novel protein
chr12_-_42237727 0.10 ENST00000548917.1
YY1 associated factor 2
chr8_-_104467042 0.10 ENST00000521573.2
ENST00000351513.7
dihydropyrimidinase
chr8_+_143734133 0.10 ENST00000527139.7
ENST00000533004.5
IQ motif and ankyrin repeat containing 1
chr13_-_75537805 0.10 ENST00000626103.1
ENST00000682242.1
ENST00000355801.4
COMM domain containing 6
chr1_-_153977260 0.10 ENST00000428469.1
jumping translocation breakpoint
chr3_-_138834752 0.10 ENST00000477593.5
ENST00000483968.5
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
chr1_-_31764035 0.10 ENST00000373655.6
adhesion G protein-coupled receptor B2
chr1_-_197775435 0.10 ENST00000620048.6
DENN domain containing 1B
chr12_-_133227117 0.09 ENST00000673940.1
anomalous homeobox
chr2_-_24360445 0.09 ENST00000443927.5
ENST00000406921.7
ENST00000412011.5
ENST00000355123.9
intersectin 2
chr3_-_142448004 0.09 ENST00000463916.5
5'-3' exoribonuclease 1
chr11_+_118607579 0.09 ENST00000530708.4
pleckstrin homology like domain family B member 1
chr14_+_58200106 0.09 ENST00000254286.9
actin related protein 10
chrX_-_154516183 0.09 ENST00000442929.1
ENST00000426266.5
ENST00000447601.7
ENST00000359889.9
ENST00000369641.7
ENST00000322269.10
ENST00000419205.5
FAM3 metabolism regulating signaling molecule A
chr2_-_219571241 0.09 ENST00000373876.5
ENST00000603926.5
ENST00000373873.8
ENST00000289656.3
obscurin like cytoskeletal adaptor 1
chr19_-_45782479 0.09 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DM1 protein kinase
chr1_+_53014926 0.09 ENST00000430330.6
ENST00000408941.7
ENST00000478274.6
ENST00000484100.5
ENST00000435345.6
ENST00000488965.1
sterol carrier protein 2
chr17_-_7393404 0.09 ENST00000575434.4
phospholipid scramblase 3
chr1_-_30723580 0.09 ENST00000373765.5
matrilin 1
chr6_-_33711717 0.09 ENST00000374214.3
ubiquinol-cytochrome c reductase complex assembly factor 2
chr2_-_69387188 0.09 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr1_-_201946469 0.09 ENST00000367288.5
leiomodin 1
chr1_+_193121950 0.09 ENST00000367435.5
cell division cycle 73
chr20_+_48921775 0.09 ENST00000681021.1
ENST00000679436.1
ADP ribosylation factor guanine nucleotide exchange factor 2
chr6_-_33711684 0.09 ENST00000374231.8
ENST00000607484.6
ubiquinol-cytochrome c reductase complex assembly factor 2
chr15_-_101489697 0.09 ENST00000611967.4
ENST00000615296.4
ENST00000611716.5
ENST00000618548.4
ENST00000619160.4
ENST00000622483.4
ENST00000559417.2
proprotein convertase subtilisin/kexin type 6

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 0.6 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.4 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.5 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 0.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.3 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.8 GO:1905098 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.2 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.8 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.8 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.5 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.2 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.2 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.2 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0006212 uracil catabolic process(GO:0006212)
0.0 0.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.8 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.1 GO:1902214 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0003221 atrioventricular node development(GO:0003162) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) positive regulation of transcription via serum response element binding(GO:0010735) His-Purkinje system cell differentiation(GO:0060932)
0.0 0.3 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.7 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.6 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.2 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.5 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0032902 zygotic determination of anterior/posterior axis, embryo(GO:0007354) nerve growth factor production(GO:0032902)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.0 GO:0071810 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.0 0.1 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.3 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.0 GO:2000295 lysosomal membrane organization(GO:0097212) regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.3 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.5 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.1 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 1.6 GO:0016015 morphogen activity(GO:0016015)
0.1 0.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.2 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.8 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.5 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 2.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.6 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression