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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOMEZ

Z-value: 0.73

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Transcription factors associated with HOMEZ

Gene Symbol Gene ID Gene Info
ENSG00000215271.9 homeobox and leucine zipper encoding

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOMEZhg38_v1_chr14_-_23286082_232861410.492.2e-01Click!

Activity profile of HOMEZ motif

Sorted Z-values of HOMEZ motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_93583212 2.07 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chrX_-_155022716 1.41 ENST00000360256.9
coagulation factor VIII
chr12_-_91146195 1.27 ENST00000548218.1
decorin
chr1_+_163069353 1.15 ENST00000531057.5
ENST00000527809.5
ENST00000367908.8
ENST00000367909.11
regulator of G protein signaling 4
chr1_+_163068775 1.14 ENST00000421743.6
regulator of G protein signaling 4
chr8_-_13276491 0.98 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr12_-_91180365 0.94 ENST00000547937.5
decorin
chr4_-_99352754 0.86 ENST00000639454.1
alcohol dehydrogenase 1B (class I), beta polypeptide
chrX_+_87517784 0.86 ENST00000373119.9
ENST00000373114.4
kelch like family member 4
chr1_+_78620722 0.73 ENST00000679848.1
interferon induced protein 44 like
chr9_+_88991440 0.73 ENST00000358157.3
sphingosine-1-phosphate receptor 3
chr22_-_28679865 0.68 ENST00000397906.6
tetratricopeptide repeat domain 28
chr11_+_62337424 0.68 ENST00000415229.6
ENST00000301776.9
ENST00000628829.2
ENST00000534571.5
ENST00000526096.2
asparaginase and isoaspartyl peptidase 1
chr2_+_200585987 0.54 ENST00000374700.7
aldehyde oxidase 1
chr14_+_75632610 0.51 ENST00000555027.1
FLVCR heme transporter 2
chrX_+_12975083 0.49 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr4_-_69760596 0.47 ENST00000510821.1
sulfotransferase family 1B member 1
chr2_+_108621260 0.45 ENST00000409441.5
LIM zinc finger domain containing 1
chr8_+_76681208 0.45 ENST00000651372.2
zinc finger homeobox 4
chr2_-_174597795 0.44 ENST00000679041.1
WAS/WASL interacting protein family member 1
chr5_+_179023794 0.43 ENST00000519896.5
ENST00000522442.1
ENST00000444149.7
zinc finger protein 879
chr19_-_53159004 0.43 ENST00000599096.1
ENST00000597183.5
ENST00000601804.5
ENST00000334197.12
ENST00000601469.2
ENST00000452676.6
zinc finger protein 347
chr19_+_15949008 0.43 ENST00000322107.1
olfactory receptor family 10 subfamily H member 4
chrX_+_12975216 0.42 ENST00000380635.5
thymosin beta 4 X-linked
chr1_-_145910031 0.42 ENST00000369304.8
integrin subunit alpha 10
chrX_-_107777038 0.42 ENST00000480691.2
ENST00000506081.5
ENST00000514426.1
TSC22 domain family member 3
chr22_+_35383106 0.40 ENST00000678411.1
heme oxygenase 1
chr12_+_59664677 0.40 ENST00000548610.5
solute carrier family 16 member 7
chr19_+_40613416 0.38 ENST00000599724.5
ENST00000597071.5
latent transforming growth factor beta binding protein 4
chr4_-_69760610 0.38 ENST00000310613.8
sulfotransferase family 1B member 1
chr14_-_94129577 0.37 ENST00000238609.4
interferon alpha inducible protein 27 like 2
chr1_+_108560031 0.37 ENST00000405454.1
ENST00000370035.8
family with sequence similarity 102 member B
chr1_-_145910066 0.37 ENST00000539363.2
integrin subunit alpha 10
chr4_+_70028452 0.37 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
histatin 3
chr19_+_22832284 0.36 ENST00000600766.3
zinc finger protein 723
chr17_+_48997377 0.36 ENST00000290341.8
insulin like growth factor 2 mRNA binding protein 1
chr6_-_11382247 0.35 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr12_+_32502114 0.35 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FYVE, RhoGEF and PH domain containing 4
chr4_-_99321362 0.34 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr19_+_44259903 0.34 ENST00000588489.5
ENST00000391958.6
zinc finger protein 233
chr15_-_55365231 0.34 ENST00000568543.1
cell cycle progression 1
chr5_-_65624288 0.33 ENST00000381018.7
ENST00000274327.11
ENST00000231524.14
tripartite motif containing 23
chrX_-_93673558 0.33 ENST00000475430.2
ENST00000373079.4
nucleosome assembly protein 1 like 3
chr7_+_28685968 0.33 ENST00000396298.6
cAMP responsive element binding protein 5
chr19_+_15944299 0.32 ENST00000641275.1
olfactory receptor family 10 subfamily H member 4
chr22_+_31754862 0.32 ENST00000382111.6
ENST00000645407.1
ENST00000646701.1
DEP domain containing 5, GATOR1 subcomplex subunit
novel protein, DEPDC5-YWHAH readthrough
chr3_+_69763549 0.32 ENST00000472437.5
melanocyte inducing transcription factor
chr2_-_43676406 0.31 ENST00000475092.4
C1GALT1 specific chaperone 1 like
chr12_+_25958891 0.31 ENST00000381352.7
ENST00000535907.5
ENST00000405154.6
ENST00000615708.4
Ras association domain family member 8
chrX_-_64976435 0.31 ENST00000374839.8
zinc finger C4H2-type containing
chr1_-_182391783 0.31 ENST00000331872.11
ENST00000339526.8
glutamate-ammonia ligase
chrX_+_54807599 0.29 ENST00000375053.6
ENST00000627068.2
ENST00000375068.6
ENST00000347546.8
MAGE family member D2
chr2_-_206218024 0.29 ENST00000407325.6
ENST00000612892.4
ENST00000411719.1
G protein-coupled receptor 1
chr12_+_25973748 0.29 ENST00000542865.5
Ras association domain family member 8
chr19_-_45424364 0.29 ENST00000589165.5
ERCC excision repair 1, endonuclease non-catalytic subunit
chr19_-_53103351 0.28 ENST00000599056.5
ENST00000599247.5
ENST00000355147.9
ENST00000683776.1
ENST00000418871.5
ENST00000429604.5
zinc finger protein 160
chr12_-_112013123 0.28 ENST00000550831.7
ENST00000549537.6
ENST00000355445.7
ENST00000552374.7
transmembrane protein 116
chrX_-_64976500 0.28 ENST00000447788.6
zinc finger C4H2-type containing
chr8_-_13514744 0.28 ENST00000316609.9
DLC1 Rho GTPase activating protein
chr5_-_160400025 0.27 ENST00000523213.1
ENST00000408953.4
zinc finger BED-type containing 8
chr16_-_88663065 0.27 ENST00000301012.8
ENST00000569177.5
mevalonate diphosphate decarboxylase
chrX_-_135296024 0.26 ENST00000370764.1
zinc finger protein 75D
chr18_-_56638427 0.26 ENST00000586262.5
ENST00000217515.11
thioredoxin like 1
chr7_-_7640009 0.26 ENST00000401447.1
replication protein A3
chr5_+_141421064 0.25 ENST00000518882.2
protocadherin gamma subfamily A, 11
chr9_-_92404559 0.25 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr17_+_39699960 0.25 ENST00000445658.6
erb-b2 receptor tyrosine kinase 2
chr10_-_62268837 0.25 ENST00000373789.8
rhotekin 2
chr19_+_44259875 0.25 ENST00000592581.5
ENST00000590668.5
ENST00000683810.1
zinc finger protein 233
chr1_+_212950572 0.24 ENST00000366968.8
ENST00000490792.1
ENST00000366964.7
vasohibin 2
chr5_-_169980474 0.24 ENST00000377365.4
inhibitory synaptic factor family member 2B
chr12_+_12611839 0.24 ENST00000228865.3
cAMP responsive element binding protein like 2
chr3_-_169869833 0.23 ENST00000523069.1
ENST00000264676.9
ENST00000316428.10
leucine rich repeat containing 31
chr3_-_49429252 0.23 ENST00000615713.4
nicolin 1
chr3_-_146544850 0.23 ENST00000472349.1
phospholipid scramblase 1
chr6_-_167157980 0.23 ENST00000366834.2
G protein-coupled receptor 31
chr1_+_96722628 0.22 ENST00000675401.1
polypyrimidine tract binding protein 2
chr19_-_12401247 0.22 ENST00000595766.1
ENST00000430385.3
ENST00000435033.1
zinc finger protein 799
novel transcript
chr1_-_150629470 0.22 ENST00000638926.1
ENST00000503241.1
ENST00000369016.8
ENST00000339643.9
ENST00000271690.12
ENST00000356527.9
ENST00000362052.7
ENST00000503345.1
ENST00000369014.10
endosulfine alpha
chr17_+_68525795 0.21 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr19_+_44113385 0.21 ENST00000262894.11
ENST00000588926.5
ENST00000592780.5
zinc finger protein 225
chr10_-_30999469 0.21 ENST00000538351.6
zinc finger protein 438
chr1_+_35931190 0.21 ENST00000246314.10
argonaute RISC catalytic component 3
chr3_-_49429304 0.20 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
novel protein
nicolin 1
chr2_-_165204042 0.20 ENST00000283254.12
ENST00000453007.1
sodium voltage-gated channel alpha subunit 3
chr20_+_11892493 0.20 ENST00000422390.5
ENST00000618918.4
BTB domain containing 3
chr18_-_12656716 0.20 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr17_+_39700000 0.20 ENST00000584450.5
erb-b2 receptor tyrosine kinase 2
chr8_+_27311471 0.19 ENST00000397501.5
protein tyrosine kinase 2 beta
chr3_-_108222362 0.19 ENST00000492106.1
intraflagellar transport 57
chr12_+_12725897 0.19 ENST00000326765.10
apolipoprotein L domain containing 1
chr19_-_38840178 0.19 ENST00000594769.5
ENST00000602021.1
novel protein
chr21_-_32727889 0.19 ENST00000630077.3
ENST00000674204.1
synaptojanin 1
chr2_+_209653171 0.19 ENST00000447185.5
microtubule associated protein 2
chr6_+_36029082 0.19 ENST00000472333.1
mitogen-activated protein kinase 14
chrX_+_103376887 0.19 ENST00000372634.1
brain expressed X-linked 3
chrX_-_120575783 0.19 ENST00000680673.1
cullin 4B
chr1_+_103749898 0.19 ENST00000622339.5
amylase alpha 1C
chr5_-_39425187 0.19 ENST00000545653.5
DAB adaptor protein 2
chr19_-_54115626 0.18 ENST00000391759.6
TCF3 fusion partner
chr1_+_196819731 0.18 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr3_-_122416035 0.18 ENST00000330689.6
WD repeat domain 5B
chr1_+_103571077 0.18 ENST00000610648.1
amylase alpha 2B
chr15_-_99249523 0.18 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
tetratricopeptide repeat domain 23
chrX_+_121047601 0.18 ENST00000328078.3
glutamate dehydrogenase 2
chr15_+_63122561 0.18 ENST00000557972.1
lactamase beta
chr12_+_50925007 0.18 ENST00000332160.5
methyltransferase like 7A
chr6_+_80106623 0.17 ENST00000369760.8
ENST00000356489.9
branched chain keto acid dehydrogenase E1 subunit beta
chr11_-_124800630 0.17 ENST00000239614.8
ENST00000674284.1
Myb/SANT DNA binding domain containing 2
chrX_+_51743395 0.17 ENST00000340438.6
G1 to S phase transition 2
chr19_-_52139904 0.16 ENST00000597013.5
ENST00000596290.5
ENST00000600228.6
zinc finger protein 616
chr19_-_18884219 0.16 ENST00000596048.1
ceramide synthase 1
chr19_+_35641728 0.16 ENST00000619399.4
ENST00000379026.6
ENST00000379023.8
ENST00000402764.6
ENST00000479824.5
ETS variant transcription factor 2
chr1_-_53220589 0.16 ENST00000294360.5
CXXC motif containing zinc binding protein
chr3_-_108222383 0.16 ENST00000264538.4
intraflagellar transport 57
chr2_-_171160833 0.16 ENST00000360843.7
ENST00000431350.7
tousled like kinase 1
chr17_+_35587239 0.16 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr3_+_11154477 0.15 ENST00000431010.3
histamine receptor H1
chr19_+_44072142 0.15 ENST00000421176.4
zinc finger protein 284
chr3_-_138594129 0.15 ENST00000485115.1
ENST00000484888.5
ENST00000468900.5
ENST00000481834.5
ENST00000264982.8
centrosomal protein 70
chr6_+_28281555 0.15 ENST00000259883.3
ENST00000682144.1
piggyBac transposable element derived 1
chrX_+_119574554 0.15 ENST00000371558.7
ENST00000630695.2
ENST00000631185.2
ubiquitin conjugating enzyme E2 A
chr6_+_20534441 0.15 ENST00000274695.8
ENST00000613575.4
CDK5 regulatory subunit associated protein 1 like 1
chr9_-_127873462 0.15 ENST00000223836.10
adenylate kinase 1
chrX_-_13938618 0.15 ENST00000454189.6
glycoprotein M6B
chr3_+_186640411 0.14 ENST00000382136.3
fetuin B
chr12_-_71157992 0.14 ENST00000247829.8
tetraspanin 8
chr1_+_174875505 0.14 ENST00000486220.5
RAB GTPase activating protein 1 like
chr15_-_55408245 0.14 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
cell cycle progression 1
chr8_+_38728186 0.14 ENST00000519416.5
ENST00000520615.5
transforming acidic coiled-coil containing protein 1
chr2_+_241350087 0.14 ENST00000451310.1
septin 2
chr12_+_71839707 0.14 ENST00000482439.6
ENST00000550746.5
ENST00000491063.5
ENST00000319106.12
ENST00000485960.7
TBC1 domain family member 15
chr20_-_36773720 0.14 ENST00000373740.7
ENST00000426836.5
ENST00000448110.6
ENST00000373750.9
ENST00000438549.5
ENST00000447406.1
ENST00000373734.8
DSN1 component of MIS12 kinetochore complex
chr12_-_71157872 0.14 ENST00000546561.2
tetraspanin 8
chr19_+_58305319 0.14 ENST00000413518.5
ENST00000427361.5
ENST00000610038.5
ENST00000608070.5
ENST00000609864.5
endogenous retrovirus group K3 member 1
chr10_-_24723185 0.14 ENST00000376410.7
ENST00000446003.5
Rho GTPase activating protein 21
chr11_-_59866478 0.14 ENST00000257264.4
transcobalamin 1
chr2_+_61145068 0.14 ENST00000426997.5
ENST00000464909.2
ENST00000489686.5
chromosome 2 open reading frame 74
chr3_+_119597874 0.14 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
phospholipase A1 member A
chr19_+_44002931 0.14 ENST00000429154.7
ENST00000585632.5
zinc finger protein 230
chr14_-_91732059 0.13 ENST00000553329.5
ENST00000256343.8
cation channel sperm associated auxiliary subunit beta
chr19_-_12734653 0.13 ENST00000592273.5
ENST00000588213.1
ENST00000242784.5
telomerase RNA component interacting RNase
chr8_+_27771942 0.13 ENST00000523566.5
establishment of sister chromatid cohesion N-acetyltransferase 2
chr3_+_46577778 0.13 ENST00000296145.6
teratocarcinoma-derived growth factor 1
chr4_-_169757873 0.13 ENST00000393381.3
histone PARylation factor 1
chr2_-_189762755 0.13 ENST00000520350.1
ENST00000521630.1
ENST00000264151.10
ENST00000517895.5
O-sialoglycoprotein endopeptidase like 1
chr10_-_80289647 0.13 ENST00000372213.8
methionine adenosyltransferase 1A
chr12_+_8843236 0.13 ENST00000541459.5
alpha-2-macroglobulin like 1
chr1_-_70354673 0.13 ENST00000370944.9
ENST00000262346.6
ankyrin repeat domain 13C
chr10_-_32378720 0.13 ENST00000375110.6
enhancer of polycomb homolog 1
chr3_-_121660892 0.13 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr5_-_141320755 0.13 ENST00000624761.1
ENST00000313368.8
TATA-box binding protein associated factor 7
chr17_+_42659264 0.12 ENST00000251412.8
tubulin gamma 2
chr4_-_98143416 0.12 ENST00000295268.4
sperm tail PG-rich repeat containing 2
chr2_-_232550537 0.12 ENST00000408957.7
tigger transposable element derived 1
chr19_-_46471484 0.12 ENST00000313683.15
ENST00000602246.1
PNMA family member 8A
chr11_-_47642519 0.12 ENST00000302503.8
ENST00000530428.1
mitochondrial carrier 2
chr17_+_32142454 0.12 ENST00000333942.10
ENST00000358365.7
ENST00000545287.7
ras homolog family member T1
chr19_-_46471407 0.12 ENST00000438932.2
PNMA family member 8A
chr11_+_59142811 0.12 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr1_-_110407633 0.12 ENST00000483260.5
ENST00000474861.6
ENST00000602318.6
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr20_+_1118590 0.12 ENST00000246015.8
ENST00000335877.11
proteasome inhibitor subunit 1
chr3_+_99817849 0.12 ENST00000421999.8
cms1 ribosomal small subunit homolog
chr20_-_5113067 0.12 ENST00000342308.10
ENST00000612323.4
ENST00000202834.11
transmembrane protein 230
chr1_+_23691742 0.12 ENST00000374550.8
ENST00000643754.2
ribosomal protein L11
chr1_+_212791828 0.12 ENST00000532324.5
ENST00000530441.5
ENST00000526641.5
ENST00000531963.5
ENST00000366973.8
ENST00000366974.9
ENST00000526997.5
ENST00000488246.6
TatD DNase domain containing 3
chr14_-_39170319 0.12 ENST00000554018.1
ENST00000330149.10
ENST00000347691.9
trafficking protein particle complex 6B
chr7_+_129126518 0.12 ENST00000467614.2
novel protein similar to mitogen-activated protein kinase kinase 2 MAP2K2
chr5_-_69369257 0.12 ENST00000509462.5
TATA-box binding protein associated factor 9
chr8_-_144426982 0.12 ENST00000526054.5
ENST00000529182.5
VPS28 subunit of ESCRT-I
chrX_+_55717733 0.12 ENST00000414239.5
ENST00000374941.9
Ras related GTP binding B
chr16_-_69339493 0.11 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
component of oligomeric golgi complex 8
chr6_+_57046532 0.11 ENST00000545356.5
KIAA1586
chr18_-_49460630 0.11 ENST00000675505.1
ENST00000442713.6
ENST00000269445.10
dymeclin
chr1_-_198540674 0.11 ENST00000489986.1
ENST00000367382.6
ATPase H+ transporting V1 subunit G3
chr1_-_77759797 0.11 ENST00000524778.1
ENST00000370794.7
ENST00000370793.5
ENST00000370792.7
ubiquitin specific peptidase 33
chr1_-_243851066 0.11 ENST00000263826.12
AKT serine/threonine kinase 3
chr12_+_133037476 0.11 ENST00000540031.5
ENST00000539354.6
ENST00000536123.5
zinc finger protein 84
chr7_+_99325857 0.11 ENST00000638617.1
ENST00000262942.10
novel protein, ARPC1A and ARPC1B readthrough
actin related protein 2/3 complex subunit 1A
chrX_+_119574530 0.11 ENST00000346330.6
ENST00000625938.2
ubiquitin conjugating enzyme E2 A
chr22_-_50532489 0.11 ENST00000329363.9
ENST00000437588.2
outer dense fiber of sperm tails 3B
chr14_-_104953899 0.11 ENST00000557457.1
AHNAK nucleoprotein 2
chr13_-_30464234 0.11 ENST00000399489.5
ENST00000339872.8
high mobility group box 1
chr17_-_7916280 0.11 ENST00000324348.9
ring finger protein 227
chr12_-_120446372 0.11 ENST00000546954.2
TP53 regulated inhibitor of apoptosis 1
chr2_+_178480446 0.11 ENST00000234453.10
pleckstrin homology domain containing A3
chr14_-_45134454 0.11 ENST00000396062.4
FKBP prolyl isomerase 3
chr16_-_27268579 0.10 ENST00000564342.5
ENST00000567710.5
ENST00000563273.5
ENST00000361439.9
NSE1 homolog, SMC5-SMC6 complex component
chr5_+_72848115 0.10 ENST00000679378.1
transportin 1
chr11_+_59142728 0.10 ENST00000528737.5
FAM111 trypsin like peptidase A
chr12_-_64759395 0.10 ENST00000258145.8
ENST00000543646.5
ENST00000542058.5
glucosamine (N-acetyl)-6-sulfatase
chr4_-_139301204 0.10 ENST00000505036.5
ENST00000539002.5
ENST00000544855.5
NADH:ubiquinone oxidoreductase subunit C1
chr1_-_193106048 0.10 ENST00000367440.3
glutaredoxin 2
chr19_+_48019726 0.10 ENST00000593413.1
epididymal sperm binding protein 1
chr9_-_13279407 0.10 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr3_-_48595267 0.10 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr4_+_168921555 0.10 ENST00000503290.1
palladin, cytoskeletal associated protein
chr11_-_119030848 0.10 ENST00000330775.9
ENST00000357590.9
ENST00000538950.5
ENST00000545985.5
solute carrier family 37 member 4
chr5_+_148394712 0.10 ENST00000513826.1
F-box protein 38
chr11_-_7963646 0.10 ENST00000328600.3
NLR family pyrin domain containing 10

Network of associatons between targets according to the STRING database.

First level regulatory network of HOMEZ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 2.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.9 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.3 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.7 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 1.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.1 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.2 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.5 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 1.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 1.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.0 0.1 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0006538 glutamate biosynthetic process(GO:0006537) glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.0 0.5 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.0 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0035359 negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.0 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.0 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0097229 sperm end piece(GO:0097229)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 2.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:1990393 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.0 0.3 GO:0097386 glial cell projection(GO:0097386)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 0.7 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.3 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0016497 substance K receptor activity(GO:0016497)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 2.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.0 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions