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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXA1

Z-value: 0.81

Motif logo

Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
ENSG00000105991.10 homeobox A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA1hg38_v1_chr7_-_27095972_270960390.849.8e-03Click!

Activity profile of HOXA1 motif

Sorted Z-values of HOXA1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10587219 3.91 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
adaptor related protein complex 1 subunit mu 2
chr16_+_71626149 1.60 ENST00000567566.1
MARVEL domain containing 3
chr8_+_94641074 1.57 ENST00000423620.6
epithelial splicing regulatory protein 1
chr1_+_2073986 1.21 ENST00000461106.6
protein kinase C zeta
chr16_+_71626175 1.17 ENST00000268485.8
ENST00000565261.1
ENST00000299952.4
MARVEL domain containing 3
chr5_+_167754918 1.15 ENST00000519204.5
teneurin transmembrane protein 2
chr12_-_95116967 1.03 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr20_+_59628609 0.90 ENST00000541461.5
phosphatase and actin regulator 3
chr1_+_183186238 0.87 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr1_-_201399525 0.85 ENST00000367313.4
ladinin 1
chr11_+_18266254 0.81 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr6_+_130366281 0.74 ENST00000617887.4
transmembrane protein 200A
chr7_-_22193824 0.60 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr16_+_83968244 0.55 ENST00000305202.9
N-terminal EF-hand calcium binding protein 2
chr6_+_89562308 0.53 ENST00000522441.5
ankyrin repeat domain 6
chr19_+_53867874 0.53 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
myeloid associated differentiation marker
chr12_-_84912705 0.49 ENST00000679933.1
ENST00000680260.1
ENST00000551010.2
ENST00000679453.1
ENST00000681281.1
solute carrier family 6 member 15
chr7_-_22193728 0.46 ENST00000620335.4
Rap guanine nucleotide exchange factor 5
chr8_-_90082871 0.45 ENST00000265431.7
calbindin 1
chr5_+_140834230 0.44 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr10_-_103855406 0.44 ENST00000355946.6
ENST00000369774.8
SH3 and PX domains 2A
chr12_-_52517929 0.42 ENST00000548409.5
keratin 5
chr2_-_75560893 0.42 ENST00000410113.5
ENST00000393913.8
eva-1 homolog A, regulator of programmed cell death
chr2_-_70835808 0.41 ENST00000410009.5
CD207 molecule
chr15_-_52295792 0.41 ENST00000261839.12
myosin VC
chr12_-_84912783 0.40 ENST00000680892.1
ENST00000266682.10
ENST00000680714.1
ENST00000552192.5
solute carrier family 6 member 15
chr3_-_112845950 0.39 ENST00000398214.5
CD200 receptor 1 like
chr20_-_23637933 0.38 ENST00000398411.5
cystatin C
chr6_-_13487593 0.38 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr9_-_5304713 0.38 ENST00000381627.4
relaxin 2
chr11_-_72642450 0.38 ENST00000444035.6
ENST00000544570.5
phosphodiesterase 2A
chr11_-_72642407 0.37 ENST00000376450.7
phosphodiesterase 2A
chr1_+_205504592 0.37 ENST00000506784.5
ENST00000360066.6
cyclin dependent kinase 18
chrX_+_135309480 0.36 ENST00000635820.1
embryonic testis differentiation homolog C
chr11_-_5441514 0.36 ENST00000380211.1
olfactory receptor family 51 subfamily I member 1
chr19_-_38256513 0.36 ENST00000347262.8
ENST00000591585.1
protein phosphatase 1 regulatory inhibitor subunit 14A
chr7_+_20330893 0.35 ENST00000222573.5
integrin subunit beta 8
chr15_-_63381835 0.33 ENST00000344366.7
ENST00000178638.8
ENST00000422263.2
carbonic anhydrase 12
chr1_+_44674688 0.33 ENST00000418644.5
ENST00000458657.6
ENST00000535358.6
ENST00000441519.5
ENST00000445071.5
armadillo like helical domain containing 1
chr1_-_24143112 0.33 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr1_+_18630839 0.32 ENST00000420770.7
paired box 7
chr16_+_2988256 0.32 ENST00000573315.2
long intergenic non-protein coding RNA 514
chr11_+_2461432 0.32 ENST00000335475.6
potassium voltage-gated channel subfamily Q member 1
chr6_-_107115493 0.30 ENST00000369042.6
BEN domain containing 3
chr1_+_202203721 0.28 ENST00000255432.11
leucine rich repeat containing G protein-coupled receptor 6
chr6_-_47042260 0.28 ENST00000371243.2
adhesion G protein-coupled receptor F1
chr3_-_129893551 0.24 ENST00000505616.5
ENST00000426664.6
ENST00000648771.1
ENST00000393238.8
transmembrane and coiled-coil domain family 1
chr8_+_97775775 0.24 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr9_+_121567057 0.24 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2 interacting protein
chr2_+_1484663 0.23 ENST00000446278.5
ENST00000469607.3
thyroid peroxidase
chr8_+_97775829 0.23 ENST00000517924.5
lysosomal protein transmembrane 4 beta
chr18_-_76495191 0.23 ENST00000443185.7
zinc finger protein 516
chrX_+_135520616 0.22 ENST00000370752.4
ENST00000639893.2
integrator complex subunit 6 like
chr3_-_179243284 0.22 ENST00000486944.2
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr1_-_206921867 0.21 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr1_+_156154371 0.20 ENST00000368282.1
semaphorin 4A
chr8_+_2045058 0.20 ENST00000523438.1
myomesin 2
chr8_+_142449430 0.20 ENST00000643448.1
ENST00000517894.5
adhesion G protein-coupled receptor B1
chr11_-_69819410 0.20 ENST00000334134.4
fibroblast growth factor 3
chr21_+_31873010 0.19 ENST00000270112.7
hormonally up-regulated Neu-associated kinase
chr8_+_85187650 0.19 ENST00000517476.5
ENST00000521429.5
E2F transcription factor 5
chr6_+_15248855 0.19 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr3_+_133038366 0.19 ENST00000321871.11
ENST00000393130.7
ENST00000514894.5
ENST00000512662.5
transmembrane protein 108
chr5_+_36151989 0.19 ENST00000274254.9
S-phase kinase associated protein 2
chr1_-_206921987 0.18 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr17_-_15598618 0.18 ENST00000583965.5
CMT1A duplicated region transcript 1
chr1_-_112956063 0.18 ENST00000538576.5
ENST00000369626.8
ENST00000458229.6
solute carrier family 16 member 1
chr2_-_60550900 0.17 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BAF chromatin remodeling complex subunit BCL11A
chr14_+_24130659 0.17 ENST00000267426.6
fat storage inducing transmembrane protein 1
chr15_+_47717344 0.17 ENST00000558816.5
ENST00000536845.7
semaphorin 6D
chr15_+_66453418 0.17 ENST00000566326.1
mitogen-activated protein kinase kinase 1
chr16_+_75222609 0.17 ENST00000495583.1
chymotrypsinogen B1
chr8_-_118111806 0.16 ENST00000378204.7
exostosin glycosyltransferase 1
chr4_-_71784046 0.16 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr3_-_161372821 0.16 ENST00000617024.1
ENST00000359175.8
serine palmitoyltransferase small subunit B
chr4_+_70334963 0.15 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr16_+_28974764 0.15 ENST00000565975.5
ENST00000311008.16
ENST00000323081.12
ENST00000334536.12
sphingolipid transporter 1 (putative)
chr15_-_22185402 0.15 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr16_+_30023198 0.15 ENST00000681219.1
ENST00000300575.6
chromosome 16 open reading frame 92
chr7_+_98106852 0.14 ENST00000297293.6
lemur tyrosine kinase 2
chrX_+_83508284 0.14 ENST00000644024.2
POU class 3 homeobox 4
chr19_-_51531790 0.14 ENST00000359982.8
ENST00000436458.5
ENST00000391797.3
ENST00000343300.8
sialic acid binding Ig like lectin 6
chr12_+_124993633 0.14 ENST00000341446.9
ENST00000671775.2
BRI3 binding protein
chr7_+_139829242 0.14 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
thromboxane A synthase 1
chr17_-_46818680 0.14 ENST00000225512.6
Wnt family member 3
chr2_+_85429448 0.14 ENST00000651736.1
SH2 domain containing 6
chr12_+_75334655 0.14 ENST00000378695.9
GLIPR1 like 1
chr12_+_75334675 0.14 ENST00000312442.2
GLIPR1 like 1
chr9_+_122519141 0.14 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr4_-_86101922 0.14 ENST00000472236.5
ENST00000641881.1
mitogen-activated protein kinase 10
chr19_-_15898057 0.14 ENST00000011989.11
ENST00000221700.11
cytochrome P450 family 4 subfamily F member 2
chr12_-_10810168 0.14 ENST00000240691.4
taste 2 receptor member 9
chr13_-_19503277 0.14 ENST00000382978.5
ENST00000400230.6
ENST00000255310.10
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr17_-_3595831 0.14 ENST00000399759.7
transient receptor potential cation channel subfamily V member 1
chrX_+_129779930 0.13 ENST00000356892.4
SAM and SH3 domain containing 3
chr19_-_11339573 0.13 ENST00000222120.8
RAB3D, member RAS oncogene family
chr5_+_36152077 0.13 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
S-phase kinase associated protein 2
chr19_+_15049469 0.13 ENST00000427043.4
caspase 14
chr15_-_74208969 0.13 ENST00000423167.6
ENST00000432245.6
signaling receptor and transporter of retinol STRA6
chr10_+_97589715 0.12 ENST00000370640.5
chromosome 10 open reading frame 62
chr17_-_40665121 0.12 ENST00000394052.5
keratin 222
chr4_-_38804783 0.12 ENST00000308979.7
ENST00000505940.1
ENST00000515861.5
toll like receptor 1
chr13_-_20161038 0.12 ENST00000241125.4
gap junction protein alpha 3
chr2_+_72887368 0.12 ENST00000234454.6
sepiapterin reductase
chr5_-_784691 0.12 ENST00000508859.8
ENST00000652055.1
ENST00000651083.1
zinc finger DHHC-type containing 11B
chr19_+_5681140 0.12 ENST00000579559.1
ENST00000577222.5
hydroxysteroid 11-beta dehydrogenase 1 like
ribosomal protein L36
chr3_+_48223479 0.12 ENST00000652295.2
cathelicidin antimicrobial peptide
chr9_-_6645712 0.12 ENST00000321612.8
glycine decarboxylase
chr16_+_23835946 0.12 ENST00000321728.12
ENST00000643927.1
protein kinase C beta
chr6_+_29170907 0.12 ENST00000641417.1
olfactory receptor family 2 subfamily J member 2
chr16_+_29663219 0.11 ENST00000436527.5
ENST00000360121.4
ENST00000652691.1
ENST00000449759.2
sialophorin
quinolinate phosphoribosyltransferase
chr7_-_117323041 0.11 ENST00000491214.1
ENST00000265441.8
Wnt family member 2
chr7_+_80135694 0.11 ENST00000457358.7
G protein subunit alpha i1
chr17_-_44199834 0.11 ENST00000587097.6
ataxin 7 like 3
chr3_+_31532901 0.11 ENST00000295770.4
STT3 oligosaccharyltransferase complex catalytic subunit B
chr11_-_18791768 0.11 ENST00000358540.7
protein tyrosine phosphatase non-receptor type 5
chr20_+_2692736 0.11 ENST00000380648.9
ENST00000497450.5
EBF family member 4
chr1_-_44141631 0.11 ENST00000634670.1
Kruppel like factor 18
chr2_-_49154507 0.11 ENST00000406846.7
follicle stimulating hormone receptor
chr11_+_4704782 0.10 ENST00000380390.6
matrix metallopeptidase 26
chr1_+_201283452 0.10 ENST00000263946.7
ENST00000367324.8
plakophilin 1
chr9_+_110668779 0.10 ENST00000416899.7
ENST00000374448.9
muscle associated receptor tyrosine kinase
chr13_-_35476682 0.10 ENST00000379919.6
mab-21 like 1
chr11_+_68460712 0.10 ENST00000528635.5
ENST00000533127.5
ENST00000529907.5
ENST00000529344.5
ENST00000534534.5
ENST00000524845.5
ENST00000393800.7
ENST00000265637.8
ENST00000524904.5
ENST00000393801.7
ENST00000265636.9
ENST00000529710.5
protein phosphatase 6 regulatory subunit 3
chr2_-_49154433 0.10 ENST00000454032.5
ENST00000304421.8
follicle stimulating hormone receptor
chr9_-_127916978 0.10 ENST00000361444.3
ENST00000335791.10
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr10_+_7703340 0.10 ENST00000429820.5
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_5227063 0.10 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr3_+_4493340 0.10 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
inositol 1,4,5-trisphosphate receptor type 1
chr3_+_150546671 0.10 ENST00000487799.5
eukaryotic translation initiation factor 2A
chrX_+_8465426 0.09 ENST00000381029.4
variable charge X-linked 3B
chr7_-_101165114 0.09 ENST00000445482.2
VGF nerve growth factor inducible
chr18_-_3874247 0.09 ENST00000581699.5
DLG associated protein 1
chr16_+_28974813 0.09 ENST00000352260.11
sphingolipid transporter 1 (putative)
chr1_-_44788168 0.09 ENST00000372207.4
bestrophin 4
chr4_+_113049616 0.09 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr5_-_137735997 0.09 ENST00000505853.1
kelch like family member 3
chr3_+_150546765 0.09 ENST00000406576.7
ENST00000460851.6
ENST00000482093.5
ENST00000273435.9
eukaryotic translation initiation factor 2A
chr20_+_37383648 0.09 ENST00000373567.6
SRC proto-oncogene, non-receptor tyrosine kinase
chr2_-_27356975 0.09 ENST00000423998.1
ENST00000264720.7
general transcription factor IIIC subunit 2
chr12_+_57216779 0.08 ENST00000349394.6
neurexophilin 4
chr3_+_4493442 0.08 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
inositol 1,4,5-trisphosphate receptor type 1
chrM_+_4467 0.08 ENST00000361453.3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr3_-_114199407 0.08 ENST00000460779.5
dopamine receptor D3
chrX_-_73214793 0.08 ENST00000373517.4
nucleosome assembly protein 1 like 2
chr18_-_3874270 0.08 ENST00000400149.7
ENST00000400155.5
ENST00000400150.7
DLG associated protein 1
chr11_+_66480007 0.08 ENST00000531863.5
ENST00000532677.5
dipeptidyl peptidase 3
chr9_+_100429511 0.08 ENST00000613183.1
Myb/SANT DNA binding domain containing 3
chr8_-_113436883 0.08 ENST00000455883.2
ENST00000297405.10
CUB and Sushi multiple domains 3
chrX_-_10677720 0.08 ENST00000453318.6
midline 1
chr13_-_77919390 0.08 ENST00000475537.2
ENST00000646605.1
endothelin receptor type B
chr9_+_110668854 0.08 ENST00000189978.10
ENST00000374440.7
muscle associated receptor tyrosine kinase
chr7_-_101165558 0.08 ENST00000611537.1
ENST00000249330.3
VGF nerve growth factor inducible
chr3_+_179347686 0.08 ENST00000471841.6
mitofusin 1
chr10_+_7703300 0.07 ENST00000358415.9
inter-alpha-trypsin inhibitor heavy chain 2
chr7_+_154305105 0.07 ENST00000332007.7
dipeptidyl peptidase like 6
chr11_+_55635113 0.07 ENST00000641760.1
olfactory receptor family 4 subfamily P member 4
chrX_+_37780049 0.07 ENST00000378588.5
cytochrome b-245 beta chain
chrX_+_15507302 0.07 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr1_-_217631034 0.07 ENST00000366934.3
ENST00000366935.8
G-patch domain containing 2
chr14_-_68979076 0.07 ENST00000538545.6
ENST00000684639.1
actinin alpha 1
chr16_-_8936633 0.07 ENST00000381886.8
ubiquitin specific peptidase 7
chr11_+_26188836 0.07 ENST00000672621.1
anoctamin 3
chr6_+_42155399 0.07 ENST00000623004.2
ENST00000372963.4
ENST00000654459.1
GUCA1A neighbor
guanylate cyclase activator 1A
chrX_+_116170742 0.07 ENST00000371906.5
ENST00000681852.1
angiotensin II receptor type 2
chr11_-_61878582 0.07 ENST00000527379.5
fatty acid desaturase 3
chr12_-_101210232 0.07 ENST00000536262.3
solute carrier family 5 member 8
chr1_+_43300971 0.07 ENST00000372476.8
ENST00000538015.1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr17_+_62370218 0.07 ENST00000450662.7
EF-hand calcium binding domain 3
chr12_+_8123899 0.07 ENST00000641376.1
C-type lectin domain family 4 member A
chr14_-_68979274 0.07 ENST00000394419.9
actinin alpha 1
chr5_-_137736066 0.07 ENST00000309755.9
kelch like family member 3
chr1_-_12848720 0.06 ENST00000317869.7
heterogeneous nuclear ribonucleoprotein C like 1
chr15_-_43220989 0.06 ENST00000540029.5
ENST00000441366.7
ENST00000648595.1
erythrocyte membrane protein band 4.2
chr14_-_68979251 0.06 ENST00000438964.6
ENST00000679147.1
actinin alpha 1
chr20_+_45408276 0.06 ENST00000372710.5
ENST00000443296.1
dysbindin domain containing 2
chr12_-_21774688 0.06 ENST00000240662.3
potassium inwardly rectifying channel subfamily J member 8
chr5_+_64505981 0.06 ENST00000334025.3
regulator of G protein signaling 7 binding protein
chr12_-_86256267 0.06 ENST00000620241.4
MGAT4 family member C
chr15_+_73443149 0.06 ENST00000560581.1
ENST00000331090.11
REC114 meiotic recombination protein
chr8_+_42338477 0.06 ENST00000518925.5
ENST00000265421.9
DNA polymerase beta
chr3_+_44874606 0.06 ENST00000296125.9
transglutaminase 4
chr14_-_68979314 0.06 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
actinin alpha 1
chr11_-_18791563 0.06 ENST00000396168.1
protein tyrosine phosphatase non-receptor type 5
chr11_+_125904467 0.06 ENST00000263576.11
ENST00000530414.5
ENST00000530129.6
DEAD-box helicase 25
chr6_-_31592952 0.06 ENST00000376073.8
ENST00000376072.7
natural cytotoxicity triggering receptor 3
chr8_+_40153475 0.06 ENST00000315792.5
transcriptional and immune response regulator
chr13_+_29428603 0.06 ENST00000380808.6
microtubule associated scaffold protein 2
chr16_-_48610150 0.06 ENST00000262384.4
NEDD4 binding protein 1
chr9_-_35563867 0.06 ENST00000399742.7
ENST00000619051.4
family with sequence similarity 166 member B
chr13_+_113209597 0.06 ENST00000488558.2
ENST00000375440.9
cullin 4A
chr12_+_63779894 0.06 ENST00000261234.11
ribitol xylosyltransferase 1
chr3_+_111542178 0.06 ENST00000283285.10
ENST00000352690.9
CD96 molecule
chr1_+_36156096 0.05 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr6_-_41154326 0.05 ENST00000426005.6
ENST00000437044.2
ENST00000373127.8
triggering receptor expressed on myeloid cells like 1
chr17_+_80178499 0.05 ENST00000570421.5
ENST00000344227.6
caspase recruitment domain family member 14
chr2_-_224569782 0.05 ENST00000409096.5
cullin 3
chr1_-_110519175 0.05 ENST00000369771.4
potassium voltage-gated channel subfamily A member 10
chr17_+_42780592 0.05 ENST00000246914.10
WNK lysine deficient protein kinase 4
chr2_-_50347789 0.05 ENST00000628364.2
neurexin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 1.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.7 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.6 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 0.3 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.1 0.3 GO:0060309 elastin catabolic process(GO:0060309)
0.1 0.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.9 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 3.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 1.2 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:1904800 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.0 0.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.8 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.0 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.1 0.9 GO:0043256 laminin complex(GO:0043256)
0.1 3.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 0.9 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 3.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.7 GO:0030911 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.1 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions