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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXA1

Z-value: 0.81

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Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
HOXA1
ENSG00000105991.10 homeobox A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA1hg38_v1_chr7_-_27095972_270960390.849.8e-03Click!

Activity profile of HOXA1 motif

Sorted Z-values of HOXA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10587219 3.91 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
AP1M2
adaptor related protein complex 1 subunit mu 2
chr16_+_71626149 1.60 ENST00000567566.1
MARVELD3
MARVEL domain containing 3
chr8_+_94641074 1.57 ENST00000423620.6
ESRP1
epithelial splicing regulatory protein 1
chr1_+_2073986 1.21 ENST00000461106.6
PRKCZ
protein kinase C zeta
chr16_+_71626175 1.17 ENST00000268485.8
ENST00000565261.1
ENST00000299952.4
MARVELD3
MARVEL domain containing 3
chr5_+_167754918 1.15 ENST00000519204.5
TENM2
teneurin transmembrane protein 2
chr12_-_95116967 1.03 ENST00000551521.5
FGD6
FYVE, RhoGEF and PH domain containing 6
chr20_+_59628609 0.90 ENST00000541461.5
PHACTR3
phosphatase and actin regulator 3
chr1_+_183186238 0.87 ENST00000493293.5
ENST00000264144.5
LAMC2
laminin subunit gamma 2
chr1_-_201399525 0.85 ENST00000367313.4
LAD1
ladinin 1
chr11_+_18266254 0.81 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
SAA1
serum amyloid A1
chr6_+_130366281 0.74 ENST00000617887.4
TMEM200A
transmembrane protein 200A
chr7_-_22193824 0.60 ENST00000401957.6
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr16_+_83968244 0.55 ENST00000305202.9
NECAB2
N-terminal EF-hand calcium binding protein 2
chr6_+_89562308 0.53 ENST00000522441.5
ANKRD6
ankyrin repeat domain 6
chr19_+_53867874 0.53 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
MYADM
myeloid associated differentiation marker
chr12_-_84912705 0.49 ENST00000679933.1
ENST00000680260.1
ENST00000551010.2
ENST00000679453.1
ENST00000681281.1
SLC6A15
solute carrier family 6 member 15
chr7_-_22193728 0.46 ENST00000620335.4
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr8_-_90082871 0.45 ENST00000265431.7
CALB1
calbindin 1
chr5_+_140834230 0.44 ENST00000356878.5
ENST00000525929.2
PCDHA7
protocadherin alpha 7
chr10_-_103855406 0.44 ENST00000355946.6
ENST00000369774.8
SH3PXD2A
SH3 and PX domains 2A
chr12_-_52517929 0.42 ENST00000548409.5
KRT5
keratin 5
chr2_-_75560893 0.42 ENST00000410113.5
ENST00000393913.8
EVA1A
eva-1 homolog A, regulator of programmed cell death
chr2_-_70835808 0.41 ENST00000410009.5
CD207
CD207 molecule
chr15_-_52295792 0.41 ENST00000261839.12
MYO5C
myosin VC
chr12_-_84912783 0.40 ENST00000680892.1
ENST00000266682.10
ENST00000680714.1
ENST00000552192.5
SLC6A15
solute carrier family 6 member 15
chr3_-_112845950 0.39 ENST00000398214.5
CD200R1L
CD200 receptor 1 like
chr20_-_23637933 0.38 ENST00000398411.5
CST3
cystatin C
chr6_-_13487593 0.38 ENST00000379287.4
ENST00000603223.1
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr9_-_5304713 0.38 ENST00000381627.4
RLN2
relaxin 2
chr11_-_72642450 0.38 ENST00000444035.6
ENST00000544570.5
PDE2A
phosphodiesterase 2A
chr11_-_72642407 0.37 ENST00000376450.7
PDE2A
phosphodiesterase 2A
chr1_+_205504592 0.37 ENST00000506784.5
ENST00000360066.6
CDK18
cyclin dependent kinase 18
chrX_+_135309480 0.36 ENST00000635820.1
ETDC
embryonic testis differentiation homolog C
chr11_-_5441514 0.36 ENST00000380211.1
OR51I1
olfactory receptor family 51 subfamily I member 1
chr19_-_38256513 0.36 ENST00000347262.8
ENST00000591585.1
PPP1R14A
protein phosphatase 1 regulatory inhibitor subunit 14A
chr7_+_20330893 0.35 ENST00000222573.5
ITGB8
integrin subunit beta 8
chr15_-_63381835 0.33 ENST00000344366.7
ENST00000178638.8
ENST00000422263.2
CA12
carbonic anhydrase 12
chr1_+_44674688 0.33 ENST00000418644.5
ENST00000458657.6
ENST00000535358.6
ENST00000441519.5
ENST00000445071.5
ARMH1
armadillo like helical domain containing 1
chr1_-_24143112 0.33 ENST00000270800.2
IL22RA1
interleukin 22 receptor subunit alpha 1
chr1_+_18630839 0.32 ENST00000420770.7
PAX7
paired box 7
chr16_+_2988256 0.32 ENST00000573315.2
LINC00514
long intergenic non-protein coding RNA 514
chr11_+_2461432 0.32 ENST00000335475.6
KCNQ1
potassium voltage-gated channel subfamily Q member 1
chr6_-_107115493 0.30 ENST00000369042.6
BEND3
BEN domain containing 3
chr1_+_202203721 0.28 ENST00000255432.11
LGR6
leucine rich repeat containing G protein-coupled receptor 6
chr6_-_47042260 0.28 ENST00000371243.2
ADGRF1
adhesion G protein-coupled receptor F1
chr3_-_129893551 0.24 ENST00000505616.5
ENST00000426664.6
ENST00000648771.1
ENST00000393238.8
TMCC1
transmembrane and coiled-coil domain family 1
chr8_+_97775775 0.24 ENST00000521545.7
LAPTM4B
lysosomal protein transmembrane 4 beta
chr9_+_121567057 0.24 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr2_+_1484663 0.23 ENST00000446278.5
ENST00000469607.3
TPO
thyroid peroxidase
chr8_+_97775829 0.23 ENST00000517924.5
LAPTM4B
lysosomal protein transmembrane 4 beta
chr18_-_76495191 0.23 ENST00000443185.7
ZNF516
zinc finger protein 516
chrX_+_135520616 0.22 ENST00000370752.4
ENST00000639893.2
INTS6L
integrator complex subunit 6 like
chr3_-_179243284 0.22 ENST00000486944.2
KCNMB3
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr1_-_206921867 0.21 ENST00000628511.2
ENST00000367091.8
FCMR
Fc fragment of IgM receptor
chr1_+_156154371 0.20 ENST00000368282.1
SEMA4A
semaphorin 4A
chr8_+_2045058 0.20 ENST00000523438.1
MYOM2
myomesin 2
chr8_+_142449430 0.20 ENST00000643448.1
ENST00000517894.5
ADGRB1
adhesion G protein-coupled receptor B1
chr11_-_69819410 0.20 ENST00000334134.4
FGF3
fibroblast growth factor 3
chr21_+_31873010 0.19 ENST00000270112.7
HUNK
hormonally up-regulated Neu-associated kinase
chr8_+_85187650 0.19 ENST00000517476.5
ENST00000521429.5
E2F5
E2F transcription factor 5
chr6_+_15248855 0.19 ENST00000397311.4
JARID2
jumonji and AT-rich interaction domain containing 2
chr3_+_133038366 0.19 ENST00000321871.11
ENST00000393130.7
ENST00000514894.5
ENST00000512662.5
TMEM108
transmembrane protein 108
chr5_+_36151989 0.19 ENST00000274254.9
SKP2
S-phase kinase associated protein 2
chr1_-_206921987 0.18 ENST00000530505.1
ENST00000442471.4
FCMR
Fc fragment of IgM receptor
chr17_-_15598618 0.18 ENST00000583965.5
CDRT1
CMT1A duplicated region transcript 1
chr1_-_112956063 0.18 ENST00000538576.5
ENST00000369626.8
ENST00000458229.6
SLC16A1
solute carrier family 16 member 1
chr2_-_60550900 0.17 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr14_+_24130659 0.17 ENST00000267426.6
FITM1
fat storage inducing transmembrane protein 1
chr15_+_47717344 0.17 ENST00000558816.5
ENST00000536845.7
SEMA6D
semaphorin 6D
chr15_+_66453418 0.17 ENST00000566326.1
MAP2K1
mitogen-activated protein kinase kinase 1
chr16_+_75222609 0.17 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr8_-_118111806 0.16 ENST00000378204.7
EXT1
exostosin glycosyltransferase 1
chr4_-_71784046 0.16 ENST00000513476.5
ENST00000273951.13
GC
GC vitamin D binding protein
chr3_-_161372821 0.16 ENST00000617024.1
ENST00000359175.8
SPTSSB
serine palmitoyltransferase small subunit B
chr4_+_70334963 0.15 ENST00000273936.6
CABS1
calcium binding protein, spermatid associated 1
chr16_+_28974764 0.15 ENST00000565975.5
ENST00000311008.16
ENST00000323081.12
ENST00000334536.12
SPNS1
sphingolipid transporter 1 (putative)
chr15_-_22185402 0.15 ENST00000557788.2
IGHV4OR15-8
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr16_+_30023198 0.15 ENST00000681219.1
ENST00000300575.6
C16orf92
chromosome 16 open reading frame 92
chr7_+_98106852 0.14 ENST00000297293.6
LMTK2
lemur tyrosine kinase 2
chrX_+_83508284 0.14 ENST00000644024.2
POU3F4
POU class 3 homeobox 4
chr19_-_51531790 0.14 ENST00000359982.8
ENST00000436458.5
ENST00000391797.3
ENST00000343300.8
SIGLEC6
sialic acid binding Ig like lectin 6
chr12_+_124993633 0.14 ENST00000341446.9
ENST00000671775.2
BRI3BP
BRI3 binding protein
chr7_+_139829242 0.14 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
TBXAS1
thromboxane A synthase 1
chr17_-_46818680 0.14 ENST00000225512.6
WNT3
Wnt family member 3
chr2_+_85429448 0.14 ENST00000651736.1
SH2D6
SH2 domain containing 6
chr12_+_75334655 0.14 ENST00000378695.9
GLIPR1L1
GLIPR1 like 1
chr12_+_75334675 0.14 ENST00000312442.2
GLIPR1L1
GLIPR1 like 1
chr9_+_122519141 0.14 ENST00000340750.1
OR1J4
olfactory receptor family 1 subfamily J member 4
chr4_-_86101922 0.14 ENST00000472236.5
ENST00000641881.1
MAPK10
mitogen-activated protein kinase 10
chr19_-_15898057 0.14 ENST00000011989.11
ENST00000221700.11
CYP4F2
cytochrome P450 family 4 subfamily F member 2
chr12_-_10810168 0.14 ENST00000240691.4
TAS2R9
taste 2 receptor member 9
chr13_-_19503277 0.14 ENST00000382978.5
ENST00000400230.6
ENST00000255310.10
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr17_-_3595831 0.14 ENST00000399759.7
TRPV1
transient receptor potential cation channel subfamily V member 1
chrX_+_129779930 0.13 ENST00000356892.4
SASH3
SAM and SH3 domain containing 3
chr19_-_11339573 0.13 ENST00000222120.8
RAB3D
RAB3D, member RAS oncogene family
chr5_+_36152077 0.13 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
SKP2
S-phase kinase associated protein 2
chr19_+_15049469 0.13 ENST00000427043.4
CASP14
caspase 14
chr15_-_74208969 0.13 ENST00000423167.6
ENST00000432245.6
STRA6
signaling receptor and transporter of retinol STRA6
chr10_+_97589715 0.12 ENST00000370640.5
C10orf62
chromosome 10 open reading frame 62
chr17_-_40665121 0.12 ENST00000394052.5
KRT222
keratin 222
chr4_-_38804783 0.12 ENST00000308979.7
ENST00000505940.1
ENST00000515861.5
TLR1
toll like receptor 1
chr13_-_20161038 0.12 ENST00000241125.4
GJA3
gap junction protein alpha 3
chr2_+_72887368 0.12 ENST00000234454.6
SPR
sepiapterin reductase
chr5_-_784691 0.12 ENST00000508859.8
ENST00000652055.1
ENST00000651083.1
ZDHHC11B
zinc finger DHHC-type containing 11B
chr19_+_5681140 0.12 ENST00000579559.1
ENST00000577222.5
HSD11B1L
RPL36
hydroxysteroid 11-beta dehydrogenase 1 like
ribosomal protein L36
chr3_+_48223479 0.12 ENST00000652295.2
CAMP
cathelicidin antimicrobial peptide
chr9_-_6645712 0.12 ENST00000321612.8
GLDC
glycine decarboxylase
chr16_+_23835946 0.12 ENST00000321728.12
ENST00000643927.1
PRKCB
protein kinase C beta
chr6_+_29170907 0.12 ENST00000641417.1
OR2J2
olfactory receptor family 2 subfamily J member 2
chr16_+_29663219 0.11 ENST00000436527.5
ENST00000360121.4
ENST00000652691.1
ENST00000449759.2
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr7_-_117323041 0.11 ENST00000491214.1
ENST00000265441.8
WNT2
Wnt family member 2
chr7_+_80135694 0.11 ENST00000457358.7
GNAI1
G protein subunit alpha i1
chr17_-_44199834 0.11 ENST00000587097.6
ATXN7L3
ataxin 7 like 3
chr3_+_31532901 0.11 ENST00000295770.4
STT3B
STT3 oligosaccharyltransferase complex catalytic subunit B
chr11_-_18791768 0.11 ENST00000358540.7
PTPN5
protein tyrosine phosphatase non-receptor type 5
chr20_+_2692736 0.11 ENST00000380648.9
ENST00000497450.5
EBF4
EBF family member 4
chr1_-_44141631 0.11 ENST00000634670.1
KLF18
Kruppel like factor 18
chr2_-_49154507 0.11 ENST00000406846.7
FSHR
follicle stimulating hormone receptor
chr11_+_4704782 0.10 ENST00000380390.6
MMP26
matrix metallopeptidase 26
chr1_+_201283452 0.10 ENST00000263946.7
ENST00000367324.8
PKP1
plakophilin 1
chr9_+_110668779 0.10 ENST00000416899.7
ENST00000374448.9
MUSK
muscle associated receptor tyrosine kinase
chr13_-_35476682 0.10 ENST00000379919.6
MAB21L1
mab-21 like 1
chr11_+_68460712 0.10 ENST00000528635.5
ENST00000533127.5
ENST00000529907.5
ENST00000529344.5
ENST00000534534.5
ENST00000524845.5
ENST00000393800.7
ENST00000265637.8
ENST00000524904.5
ENST00000393801.7
ENST00000265636.9
ENST00000529710.5
PPP6R3
protein phosphatase 6 regulatory subunit 3
chr2_-_49154433 0.10 ENST00000454032.5
ENST00000304421.8
FSHR
follicle stimulating hormone receptor
chr9_-_127916978 0.10 ENST00000361444.3
ENST00000335791.10
ST6GALNAC4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr10_+_7703340 0.10 ENST00000429820.5
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_5227063 0.10 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
HBB
hemoglobin subunit beta
chr3_+_4493340 0.10 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr3_+_150546671 0.10 ENST00000487799.5
EIF2A
eukaryotic translation initiation factor 2A
chrX_+_8465426 0.09 ENST00000381029.4
VCX3B
variable charge X-linked 3B
chr7_-_101165114 0.09 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr18_-_3874247 0.09 ENST00000581699.5
DLGAP1
DLG associated protein 1
chr16_+_28974813 0.09 ENST00000352260.11
SPNS1
sphingolipid transporter 1 (putative)
chr1_-_44788168 0.09 ENST00000372207.4
BEST4
bestrophin 4
chr4_+_113049616 0.09 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ANK2
ankyrin 2
chr5_-_137735997 0.09 ENST00000505853.1
KLHL3
kelch like family member 3
chr3_+_150546765 0.09 ENST00000406576.7
ENST00000460851.6
ENST00000482093.5
ENST00000273435.9
EIF2A
eukaryotic translation initiation factor 2A
chr20_+_37383648 0.09 ENST00000373567.6
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
chr2_-_27356975 0.09 ENST00000423998.1
ENST00000264720.7
GTF3C2
general transcription factor IIIC subunit 2
chr12_+_57216779 0.08 ENST00000349394.6
NXPH4
neurexophilin 4
chr3_+_4493442 0.08 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chrM_+_4467 0.08 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr3_-_114199407 0.08 ENST00000460779.5
DRD3
dopamine receptor D3
chrX_-_73214793 0.08 ENST00000373517.4
NAP1L2
nucleosome assembly protein 1 like 2
chr18_-_3874270 0.08 ENST00000400149.7
ENST00000400155.5
ENST00000400150.7
DLGAP1
DLG associated protein 1
chr11_+_66480007 0.08 ENST00000531863.5
ENST00000532677.5
DPP3
dipeptidyl peptidase 3
chr9_+_100429511 0.08 ENST00000613183.1
MSANTD3
Myb/SANT DNA binding domain containing 3
chr8_-_113436883 0.08 ENST00000455883.2
ENST00000297405.10
CSMD3
CUB and Sushi multiple domains 3
chrX_-_10677720 0.08 ENST00000453318.6
MID1
midline 1
chr13_-_77919390 0.08 ENST00000475537.2
ENST00000646605.1
EDNRB
endothelin receptor type B
chr9_+_110668854 0.08 ENST00000189978.10
ENST00000374440.7
MUSK
muscle associated receptor tyrosine kinase
chr7_-_101165558 0.08 ENST00000611537.1
ENST00000249330.3
VGF
VGF nerve growth factor inducible
chr3_+_179347686 0.08 ENST00000471841.6
MFN1
mitofusin 1
chr10_+_7703300 0.07 ENST00000358415.9
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr7_+_154305105 0.07 ENST00000332007.7
DPP6
dipeptidyl peptidase like 6
chr11_+_55635113 0.07 ENST00000641760.1
OR4P4
olfactory receptor family 4 subfamily P member 4
chrX_+_37780049 0.07 ENST00000378588.5
CYBB
cytochrome b-245 beta chain
chrX_+_15507302 0.07 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr1_-_217631034 0.07 ENST00000366934.3
ENST00000366935.8
GPATCH2
G-patch domain containing 2
chr14_-_68979076 0.07 ENST00000538545.6
ENST00000684639.1
ACTN1
actinin alpha 1
chr16_-_8936633 0.07 ENST00000381886.8
USP7
ubiquitin specific peptidase 7
chr11_+_26188836 0.07 ENST00000672621.1
ANO3
anoctamin 3
chr6_+_42155399 0.07 ENST00000623004.2
ENST00000372963.4
ENST00000654459.1
GUCA1ANB
GUCA1A
GUCA1A neighbor
guanylate cyclase activator 1A
chrX_+_116170742 0.07 ENST00000371906.5
ENST00000681852.1
AGTR2
angiotensin II receptor type 2
chr11_-_61878582 0.07 ENST00000527379.5
FADS3
fatty acid desaturase 3
chr12_-_101210232 0.07 ENST00000536262.3
SLC5A8
solute carrier family 5 member 8
chr1_+_43300971 0.07 ENST00000372476.8
ENST00000538015.1
TIE1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr17_+_62370218 0.07 ENST00000450662.7
EFCAB3
EF-hand calcium binding domain 3
chr12_+_8123899 0.07 ENST00000641376.1
CLEC4A
C-type lectin domain family 4 member A
chr14_-_68979274 0.07 ENST00000394419.9
ACTN1
actinin alpha 1
chr5_-_137736066 0.07 ENST00000309755.9
KLHL3
kelch like family member 3
chr1_-_12848720 0.06 ENST00000317869.7
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C like 1
chr15_-_43220989 0.06 ENST00000540029.5
ENST00000441366.7
ENST00000648595.1
EPB42
erythrocyte membrane protein band 4.2
chr14_-_68979251 0.06 ENST00000438964.6
ENST00000679147.1
ACTN1
actinin alpha 1
chr20_+_45408276 0.06 ENST00000372710.5
ENST00000443296.1
DBNDD2
dysbindin domain containing 2
chr12_-_21774688 0.06 ENST00000240662.3
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr5_+_64505981 0.06 ENST00000334025.3
RGS7BP
regulator of G protein signaling 7 binding protein
chr12_-_86256267 0.06 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr15_+_73443149 0.06 ENST00000560581.1
ENST00000331090.11
REC114
REC114 meiotic recombination protein
chr8_+_42338477 0.06 ENST00000518925.5
ENST00000265421.9
POLB
DNA polymerase beta
chr3_+_44874606 0.06 ENST00000296125.9
TGM4
transglutaminase 4
chr14_-_68979314 0.06 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
ACTN1
actinin alpha 1
chr11_-_18791563 0.06 ENST00000396168.1
PTPN5
protein tyrosine phosphatase non-receptor type 5
chr11_+_125904467 0.06 ENST00000263576.11
ENST00000530414.5
ENST00000530129.6
DDX25
DEAD-box helicase 25
chr6_-_31592952 0.06 ENST00000376073.8
ENST00000376072.7
NCR3
natural cytotoxicity triggering receptor 3
chr8_+_40153475 0.06 ENST00000315792.5
TCIM
transcriptional and immune response regulator
chr13_+_29428603 0.06 ENST00000380808.6
MTUS2
microtubule associated scaffold protein 2
chr16_-_48610150 0.06 ENST00000262384.4
N4BP1
NEDD4 binding protein 1
chr9_-_35563867 0.06 ENST00000399742.7
ENST00000619051.4
FAM166B
family with sequence similarity 166 member B
chr13_+_113209597 0.06 ENST00000488558.2
ENST00000375440.9
CUL4A
cullin 4A
chr12_+_63779894 0.06 ENST00000261234.11
RXYLT1
ribitol xylosyltransferase 1
chr3_+_111542178 0.06 ENST00000283285.10
ENST00000352690.9
CD96
CD96 molecule
chr1_+_36156096 0.05 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7D1
MAP7 domain containing 1
chr6_-_41154326 0.05 ENST00000426005.6
ENST00000437044.2
ENST00000373127.8
TREML1
triggering receptor expressed on myeloid cells like 1
chr17_+_80178499 0.05 ENST00000570421.5
ENST00000344227.6
CARD14
caspase recruitment domain family member 14
chr2_-_224569782 0.05 ENST00000409096.5
CUL3
cullin 3
chr1_-_110519175 0.05 ENST00000369771.4
KCNA10
potassium voltage-gated channel subfamily A member 10
chr17_+_42780592 0.05 ENST00000246914.10
WNK4
WNK lysine deficient protein kinase 4
chr2_-_50347789 0.05 ENST00000628364.2
NRXN1
neurexin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 1.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.7 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.6 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 0.3 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.1 0.3 GO:0060309 elastin catabolic process(GO:0060309)
0.1 0.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.9 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 3.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 1.2 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:1904800 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.0 0.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.8 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.0 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.1 0.9 GO:0043256 laminin complex(GO:0043256)
0.1 3.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 0.9 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 3.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.7 GO:0030911 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.1 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions