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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXA4

Z-value: 0.71

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Transcription factors associated with HOXA4

Gene Symbol Gene ID Gene Info
HOXA4
ENSG00000197576.14 homeobox A4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA4hg38_v1_chr7_-_27130182_27130226-0.551.6e-01Click!

Activity profile of HOXA4 motif

Sorted Z-values of HOXA4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_104085847 1.81 ENST00000648076.2
COL17A1
collagen type XVII alpha 1 chain
chr5_+_53480619 1.56 ENST00000396947.7
ENST00000256759.8
FST
follistatin
chr5_-_1882902 0.94 ENST00000231357.7
IRX4
iroquois homeobox 4
chr5_+_67004618 0.78 ENST00000261569.11
ENST00000436277.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr14_-_53956811 0.60 ENST00000559087.5
ENST00000245451.9
BMP4
bone morphogenetic protein 4
chr4_+_83536097 0.56 ENST00000395226.6
ENST00000264409.5
GPAT3
glycerol-3-phosphate acyltransferase 3
chr18_+_31376777 0.55 ENST00000308128.9
ENST00000359747.4
DSG4
desmoglein 4
chr15_+_90201301 0.53 ENST00000411539.6
SEMA4B
semaphorin 4B
chr8_-_42501224 0.52 ENST00000520262.6
ENST00000517366.1
SLC20A2
solute carrier family 20 member 2
chr1_-_204359885 0.43 ENST00000414478.1
ENST00000272203.8
PLEKHA6
pleckstrin homology domain containing A6
chrX_-_85379659 0.43 ENST00000262753.9
POF1B
POF1B actin binding protein
chr6_+_121437378 0.41 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr11_+_112175526 0.39 ENST00000532612.5
ENST00000438022.5
BCO2
beta-carotene oxygenase 2
chr12_+_29223730 0.38 ENST00000547116.5
FAR2
fatty acyl-CoA reductase 2
chr12_+_29223659 0.38 ENST00000182377.8
FAR2
fatty acyl-CoA reductase 2
chr17_-_41382298 0.37 ENST00000394001.3
KRT34
keratin 34
chr1_+_81306096 0.37 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
ADGRL2
adhesion G protein-coupled receptor L2
chr14_-_37595224 0.36 ENST00000250448.5
FOXA1
forkhead box A1
chr11_+_112175501 0.36 ENST00000357685.11
ENST00000361053.8
BCO2
beta-carotene oxygenase 2
chr13_-_46142834 0.35 ENST00000674665.1
LCP1
lymphocyte cytosolic protein 1
chr1_-_216805367 0.35 ENST00000360012.7
ESRRG
estrogen related receptor gamma
chr2_-_68871382 0.33 ENST00000295379.2
BMP10
bone morphogenetic protein 10
chr18_-_55351977 0.32 ENST00000643689.1
TCF4
transcription factor 4
chr18_-_55422492 0.31 ENST00000561992.5
ENST00000630712.2
TCF4
transcription factor 4
chr5_+_148203024 0.30 ENST00000325630.3
SPINK6
serine peptidase inhibitor Kazal type 6
chr11_+_128694052 0.30 ENST00000527786.7
ENST00000534087.3
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_128693887 0.29 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_-_38557459 0.29 ENST00000511561.1
LIFR
LIF receptor subunit alpha
chr5_+_148202771 0.29 ENST00000514389.5
ENST00000621437.4
SPINK6
serine peptidase inhibitor Kazal type 6
chr7_+_144355288 0.28 ENST00000498580.5
ENST00000056217.10
ARHGEF5
Rho guanine nucleotide exchange factor 5
chr12_-_23951020 0.28 ENST00000441133.2
ENST00000545921.5
SOX5
SRY-box transcription factor 5
chr7_+_95485898 0.27 ENST00000428113.5
ASB4
ankyrin repeat and SOCS box containing 4
chrX_-_120311533 0.27 ENST00000440464.5
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr18_-_31162849 0.27 ENST00000257197.7
ENST00000257198.6
DSC1
desmocollin 1
chr11_-_16356538 0.26 ENST00000683767.1
SOX6
SRY-box transcription factor 6
chrX_-_120311452 0.26 ENST00000371369.9
TMEM255A
transmembrane protein 255A
chrX_-_120311408 0.25 ENST00000309720.9
TMEM255A
transmembrane protein 255A
chr20_+_54475584 0.24 ENST00000262593.10
DOK5
docking protein 5
chrX_+_135520616 0.24 ENST00000370752.4
ENST00000639893.2
INTS6L
integrator complex subunit 6 like
chr11_-_59615673 0.23 ENST00000263847.6
OSBP
oxysterol binding protein
chr2_+_127645864 0.23 ENST00000544369.5
GPR17
G protein-coupled receptor 17
chr17_+_39738317 0.22 ENST00000394211.7
GRB7
growth factor receptor bound protein 7
chr8_-_94436926 0.21 ENST00000481490.3
FSBP
fibrinogen silencer binding protein
chr18_+_44680093 0.21 ENST00000426838.8
ENST00000677068.1
SETBP1
SET binding protein 1
chr18_-_26548527 0.21 ENST00000580059.7
KCTD1
potassium channel tetramerization domain containing 1
chr1_+_160190567 0.20 ENST00000368078.8
CASQ1
calsequestrin 1
chr14_+_39265278 0.20 ENST00000554392.5
ENST00000555716.5
ENST00000341749.7
ENST00000557038.5
MIA2
MIA SH3 domain ER export factor 2
chr2_+_127646145 0.19 ENST00000486700.2
ENST00000272644.7
GPR17
G protein-coupled receptor 17
chr17_-_50707855 0.19 ENST00000285243.7
ANKRD40
ankyrin repeat domain 40
chrX_-_85379703 0.19 ENST00000373145.3
POF1B
POF1B actin binding protein
chr19_-_1021114 0.18 ENST00000333175.9
ENST00000356663.8
TMEM259
transmembrane protein 259
chr2_+_176151543 0.17 ENST00000306324.4
HOXD4
homeobox D4
chr15_+_74788542 0.16 ENST00000567571.5
CSK
C-terminal Src kinase
chr4_-_152352800 0.16 ENST00000393956.9
FBXW7
F-box and WD repeat domain containing 7
chr14_+_45135917 0.15 ENST00000267430.10
ENST00000556036.5
ENST00000542564.6
FANCM
FA complementation group M
chrM_+_5824 0.15 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr2_+_170715317 0.15 ENST00000375281.4
SP5
Sp5 transcription factor
chr10_-_60572599 0.14 ENST00000503366.5
ANK3
ankyrin 3
chrX_-_123623155 0.14 ENST00000618150.4
THOC2
THO complex 2
chr2_+_53767772 0.14 ENST00000295304.5
CHAC2
ChaC glutathione specific gamma-glutamylcyclotransferase 2
chr19_+_49591170 0.14 ENST00000418929.7
PRR12
proline rich 12
chr10_-_67696115 0.14 ENST00000433211.7
CTNNA3
catenin alpha 3
chr12_+_56128217 0.14 ENST00000267113.4
ENST00000394048.10
ESYT1
extended synaptotagmin 1
chrX_+_37780049 0.14 ENST00000378588.5
CYBB
cytochrome b-245 beta chain
chr3_-_52452828 0.13 ENST00000496590.1
TNNC1
troponin C1, slow skeletal and cardiac type
chr12_+_54053815 0.13 ENST00000430889.3
HOXC4
homeobox C4
chr16_+_7332839 0.13 ENST00000355637.9
RBFOX1
RNA binding fox-1 homolog 1
chr5_+_66958870 0.12 ENST00000405643.5
ENST00000407621.1
ENST00000432426.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr12_-_95073490 0.12 ENST00000330677.7
NR2C1
nuclear receptor subfamily 2 group C member 1
chr17_-_40799939 0.12 ENST00000306658.8
KRT28
keratin 28
chrX_+_41689006 0.12 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
GPR34
G protein-coupled receptor 34
chr3_-_120682215 0.12 ENST00000283871.10
HGD
homogentisate 1,2-dioxygenase
chrX_+_41688967 0.12 ENST00000378142.9
GPR34
G protein-coupled receptor 34
chr17_+_42844573 0.12 ENST00000253799.8
ENST00000452774.2
AOC2
amine oxidase copper containing 2
chr6_+_99606833 0.11 ENST00000369215.5
PRDM13
PR/SET domain 13
chr7_+_95485934 0.11 ENST00000325885.6
ASB4
ankyrin repeat and SOCS box containing 4
chr6_+_12716554 0.11 ENST00000676159.1
PHACTR1
phosphatase and actin regulator 1
chr9_+_84669760 0.11 ENST00000304053.10
NTRK2
neurotrophic receptor tyrosine kinase 2
chr3_+_188947199 0.11 ENST00000433971.5
TPRG1
tumor protein p63 regulated 1
chr5_-_77638713 0.11 ENST00000306422.5
OTP
orthopedia homeobox
chr4_+_15427998 0.10 ENST00000444304.3
C1QTNF7
C1q and TNF related 7
chr17_-_10518536 0.10 ENST00000226207.6
MYH1
myosin heavy chain 1
chr17_-_10549652 0.10 ENST00000245503.10
MYH2
myosin heavy chain 2
chr5_-_88883701 0.10 ENST00000636998.1
MEF2C
myocyte enhancer factor 2C
chr6_+_12716801 0.10 ENST00000674595.1
PHACTR1
phosphatase and actin regulator 1
chr6_+_12716760 0.10 ENST00000332995.12
PHACTR1
phosphatase and actin regulator 1
chr6_+_32439866 0.10 ENST00000374982.5
ENST00000395388.7
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr3_+_121593363 0.09 ENST00000338040.6
FBXO40
F-box protein 40
chr17_-_10549612 0.09 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
MYH2
myosin heavy chain 2
chr1_+_155689074 0.09 ENST00000343043.7
ENST00000421487.6
ENST00000535183.5
ENST00000368336.10
ENST00000465375.5
ENST00000470830.5
DAP3
death associated protein 3
chr18_-_23437927 0.09 ENST00000578520.5
ENST00000383233.8
TMEM241
transmembrane protein 241
chr8_-_10655137 0.09 ENST00000382483.4
RP1L1
RP1 like 1
chr12_-_86256267 0.09 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr14_-_36519679 0.09 ENST00000498187.6
NKX2-1
NK2 homeobox 1
chr17_-_10549694 0.09 ENST00000622564.4
MYH2
myosin heavy chain 2
chr14_+_22515623 0.09 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr16_+_7332744 0.08 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RBFOX1
RNA binding fox-1 homolog 1
chr3_+_122384167 0.08 ENST00000232125.9
ENST00000477892.5
ENST00000469967.1
FAM162A
family with sequence similarity 162 member A
chr17_-_48593748 0.08 ENST00000239151.6
HOXB5
homeobox B5
chr7_+_107470050 0.08 ENST00000304402.6
GPR22
G protein-coupled receptor 22
chr11_-_69819410 0.08 ENST00000334134.4
FGF3
fibroblast growth factor 3
chr2_-_179562576 0.08 ENST00000336917.9
ZNF385B
zinc finger protein 385B
chr12_+_49750598 0.08 ENST00000552370.5
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr6_+_50818857 0.08 ENST00000393655.4
TFAP2B
transcription factor AP-2 beta
chr6_-_55875583 0.08 ENST00000370830.4
BMP5
bone morphogenetic protein 5
chr11_+_27041313 0.08 ENST00000528583.5
BBOX1
gamma-butyrobetaine hydroxylase 1
chr5_+_55853464 0.08 ENST00000652039.1
IL31RA
interleukin 31 receptor A
chrX_-_111410420 0.07 ENST00000371993.7
ENST00000680476.1
DCX
doublecortin
chr10_+_113125536 0.07 ENST00000349937.7
TCF7L2
transcription factor 7 like 2
chr2_-_80304700 0.07 ENST00000295057.4
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr1_-_156490599 0.07 ENST00000360595.7
MEF2D
myocyte enhancer factor 2D
chr20_+_54475647 0.07 ENST00000395939.5
DOK5
docking protein 5
chr9_+_84669707 0.07 ENST00000277120.8
ENST00000323115.10
NTRK2
neurotrophic receptor tyrosine kinase 2
chr12_+_53425070 0.07 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor type 2
chr13_-_83882390 0.07 ENST00000377084.3
SLITRK1
SLIT and NTRK like family member 1
chr6_+_151690492 0.07 ENST00000404742.5
ENST00000440973.5
ESR1
estrogen receptor 1
chr2_-_80304274 0.06 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr1_+_167329044 0.06 ENST00000367862.9
POU2F1
POU class 2 homeobox 1
chr13_-_83882456 0.06 ENST00000674365.1
SLITRK1
SLIT and NTRK like family member 1
chr12_+_71664352 0.06 ENST00000547843.1
THAP2
THAP domain containing 2
chr1_-_100178215 0.06 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
LRRC39
leucine rich repeat containing 39
chr6_-_116126120 0.06 ENST00000452729.1
ENST00000651968.1
ENST00000243222.8
COL10A1
collagen type X alpha 1 chain
chr2_-_2324323 0.06 ENST00000648339.1
ENST00000647694.1
MYT1L
myelin transcription factor 1 like
chr13_-_52848632 0.05 ENST00000377942.7
ENST00000338862.5
PCDH8
protocadherin 8
chrX_-_54998530 0.05 ENST00000545676.5
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr12_-_95073580 0.05 ENST00000393101.7
ENST00000333003.10
ENST00000622476.4
NR2C1
nuclear receptor subfamily 2 group C member 1
chr7_+_114416286 0.05 ENST00000635534.1
FOXP2
forkhead box P2
chr11_+_22666604 0.04 ENST00000454584.6
GAS2
growth arrest specific 2
chr3_+_52414523 0.04 ENST00000461861.5
PHF7
PHD finger protein 7
chr14_-_20436161 0.04 ENST00000636854.3
KLHL33
kelch like family member 33
chr8_-_28490220 0.04 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
FBXO16
F-box protein 16
chr8_-_66178455 0.03 ENST00000276571.5
CRH
corticotropin releasing hormone
chr19_+_33373694 0.03 ENST00000284000.9
CEBPG
CCAAT enhancer binding protein gamma
chr7_+_129375643 0.03 ENST00000490911.5
AHCYL2
adenosylhomocysteinase like 2
chr9_+_92964272 0.03 ENST00000468206.6
FGD3
FYVE, RhoGEF and PH domain containing 3
chr3_+_107523026 0.03 ENST00000416476.6
BBX
BBX high mobility group box domain containing
chr5_+_153490727 0.03 ENST00000340592.9
GRIA1
glutamate ionotropic receptor AMPA type subunit 1
chr12_+_106582996 0.02 ENST00000392842.6
RFX4
regulatory factor X4
chr5_+_70025247 0.02 ENST00000380751.9
ENST00000380750.8
ENST00000503931.5
ENST00000506542.1
SERF1B
small EDRK-rich factor 1B
chr8_-_98942557 0.02 ENST00000523601.5
STK3
serine/threonine kinase 3
chr10_-_73655984 0.02 ENST00000394810.3
SYNPO2L
synaptopodin 2 like
chr4_-_184217854 0.02 ENST00000296741.7
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr18_+_3247778 0.02 ENST00000217652.8
ENST00000578611.5
ENST00000583449.1
MYL12A
myosin light chain 12A
chr11_+_92224801 0.02 ENST00000525166.6
FAT3
FAT atypical cadherin 3
chr2_-_190062721 0.02 ENST00000260950.5
MSTN
myostatin
chr10_+_116545907 0.02 ENST00000369221.2
PNLIP
pancreatic lipase
chr10_-_119178791 0.02 ENST00000298510.4
PRDX3
peroxiredoxin 3
chr15_+_36702009 0.02 ENST00000562489.1
CDIN1
CDAN1 interacting nuclease 1
chr5_+_141430565 0.01 ENST00000613314.1
PCDHGA12
protocadherin gamma subfamily A, 12
chr7_+_117611617 0.01 ENST00000468795.1
CFTR
CF transmembrane conductance regulator
chr7_-_141014629 0.01 ENST00000393008.7
MRPS33
mitochondrial ribosomal protein S33
chr12_-_120369156 0.01 ENST00000257552.7
MSI1
musashi RNA binding protein 1
chr1_+_213987929 0.01 ENST00000498508.6
ENST00000366958.9
PROX1
prospero homeobox 1
chr2_+_167187364 0.01 ENST00000672671.1
XIRP2
xin actin binding repeat containing 2
chr17_-_10421944 0.01 ENST00000403437.2
MYH8
myosin heavy chain 8
chr20_+_33562306 0.01 ENST00000344201.7
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr1_+_213988501 0.01 ENST00000261454.8
ENST00000435016.2
PROX1
prospero homeobox 1
chr1_+_26021768 0.01 ENST00000374280.4
EXTL1
exostosin like glycosyltransferase 1
chr7_+_32957385 0.01 ENST00000538336.5
ENST00000242209.9
FKBP9
FKBP prolyl isomerase 9
chr12_-_56643499 0.01 ENST00000551570.5
ATP5F1B
ATP synthase F1 subunit beta
chr17_+_56153458 0.00 ENST00000318698.6
ENST00000682825.1
ENST00000566473.6
ANKFN1
ankyrin repeat and fibronectin type III domain containing 1
chr4_+_87832917 0.00 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr3_+_107522936 0.00 ENST00000415149.6
ENST00000402543.5
ENST00000325805.13
ENST00000427402.5
BBX
BBX high mobility group box domain containing
chr1_+_28259473 0.00 ENST00000253063.4
SESN2
sestrin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.2 0.7 GO:0016116 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.2 0.6 GO:0072099 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.4 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.4 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 1.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926) positive regulation of hair follicle development(GO:0051798)
0.1 0.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 1.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.2 GO:0014894 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.0 1.9 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.0 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) negative regulation of glucagon secretion(GO:0070093) cellular response to cocaine(GO:0071314)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.4 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 1.6 GO:0048185 activin binding(GO:0048185)
0.1 0.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis