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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXB3

Z-value: 0.91

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
ENSG00000120093.12 homeobox B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB3hg38_v1_chr17_-_48590231_485902580.982.1e-05Click!

Activity profile of HOXB3 motif

Sorted Z-values of HOXB3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_36608146 1.56 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr4_+_40196907 1.34 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr18_+_63887698 1.33 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr3_-_151316795 1.31 ENST00000260843.5
G protein-coupled receptor 87
chr11_-_118264282 1.30 ENST00000278937.7
myelin protein zero like 2
chr8_-_41309434 1.26 ENST00000220772.8
secreted frizzled related protein 1
chr12_-_122716790 1.17 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr1_+_156061142 1.15 ENST00000361084.10
RAB25, member RAS oncogene family
chr12_-_122703346 1.08 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr5_+_140848360 1.04 ENST00000532602.2
protocadherin alpha 9
chr4_+_40197023 0.98 ENST00000381799.10
ras homolog family member H
chr3_-_112846856 0.98 ENST00000488794.5
CD200 receptor 1 like
chr7_+_26291850 0.95 ENST00000338523.9
ENST00000446848.6
sorting nexin 10
chr11_-_120120880 0.92 ENST00000526881.1
tripartite motif containing 29
chr1_+_27934980 0.88 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr11_-_118264445 0.87 ENST00000438295.2
myelin protein zero like 2
chr1_+_152514474 0.87 ENST00000368790.4
cysteine rich C-terminal 1
chr18_+_58221535 0.83 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr4_+_76435216 0.76 ENST00000296043.7
shroom family member 3
chr3_-_112845950 0.71 ENST00000398214.5
CD200 receptor 1 like
chr1_+_160400543 0.71 ENST00000368061.3
VANGL planar cell polarity protein 2
chr11_-_124320197 0.70 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr12_-_6631632 0.70 ENST00000431922.1
lysophosphatidic acid receptor 5
chr8_+_144148027 0.67 ENST00000423230.6
maestro heat like repeat family member 1
chr5_+_36606355 0.67 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chrX_+_139530730 0.61 ENST00000218099.7
coagulation factor IX
chr11_+_121576760 0.60 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr9_+_128149447 0.56 ENST00000277480.7
ENST00000372998.1
lipocalin 2
chr4_-_25863537 0.52 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr11_+_65787056 0.50 ENST00000335987.8
ovo like transcriptional repressor 1
chr3_+_136819069 0.46 ENST00000393079.3
ENST00000446465.3
solute carrier family 35 member G2
chr6_+_47698574 0.46 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr6_+_47698538 0.45 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr3_-_161105399 0.41 ENST00000652593.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr14_+_61187544 0.41 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr6_-_53510445 0.40 ENST00000509541.5
glutamate-cysteine ligase catalytic subunit
chr3_-_161105224 0.39 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr8_-_17722217 0.38 ENST00000381861.7
microtubule associated scaffold protein 1
chr19_-_3557563 0.38 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr1_+_161721563 0.37 ENST00000367948.6
Fc receptor like B
chr4_+_143433491 0.37 ENST00000512843.1
GRB2 associated binding protein 1
chr4_+_94974984 0.37 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr7_-_33062750 0.37 ENST00000610140.7
5'-nucleotidase, cytosolic IIIA
chr1_+_207053229 0.36 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr2_-_101308681 0.36 ENST00000295317.4
ring finger protein 149
chr3_-_161105070 0.35 ENST00000651430.1
ENST00000650695.1
ENST00000651689.1
ENST00000651916.1
ENST00000488170.5
ENST00000652377.1
ENST00000652669.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chrX_-_24672654 0.35 ENST00000379145.5
phosphate cytidylyltransferase 1, choline, beta
chr11_-_60183011 0.33 ENST00000533023.5
ENST00000420732.6
ENST00000528851.6
membrane spanning 4-domains A6A
chr12_-_51028234 0.32 ENST00000547688.7
ENST00000394904.9
solute carrier family 11 member 2
chr19_+_9185594 0.31 ENST00000344248.4
olfactory receptor family 7 subfamily D member 2
chr9_+_121567057 0.31 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2 interacting protein
chr8_+_49911801 0.30 ENST00000643809.1
syntrophin gamma 1
chr1_+_81306096 0.30 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr14_+_94174284 0.29 ENST00000304338.8
protein phosphatase 4 regulatory subunit 4
chr3_+_122055355 0.29 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr8_+_97869040 0.29 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
matrilin 2
chr9_+_470291 0.29 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr12_+_20695553 0.29 ENST00000545102.1
solute carrier organic anion transporter family member 1C1
chr12_-_91058016 0.29 ENST00000266719.4
keratocan
chr13_+_73058993 0.28 ENST00000377687.6
Kruppel like factor 5
chr9_+_131289685 0.28 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr12_+_6199715 0.28 ENST00000382518.6
ENST00000642746.1
ENST00000538834.6
CD9 molecule
chr19_+_1077394 0.28 ENST00000590577.2
Rho GTPase activating protein 45
chr6_+_130018565 0.28 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr12_-_7936177 0.28 ENST00000544291.1
ENST00000075120.12
solute carrier family 2 member 3
chr7_-_135211313 0.26 ENST00000682802.1
ENST00000683848.1
ENST00000354475.5
WD repeat domain 91
chr8_-_85341705 0.26 ENST00000517618.5
carbonic anhydrase 1
chr7_-_101217569 0.26 ENST00000223127.8
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr4_+_122378966 0.25 ENST00000446706.5
ENST00000296513.7
adenosine deaminase domain containing 1
chr9_-_5339874 0.24 ENST00000223862.2
relaxin 1
chr21_-_26051023 0.23 ENST00000415997.1
amyloid beta precursor protein
chr1_+_160190567 0.23 ENST00000368078.8
calsequestrin 1
chr8_-_30812867 0.22 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr11_-_107858777 0.22 ENST00000525815.6
solute carrier family 35 member F2
chr16_+_11965193 0.22 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr1_-_201171545 0.22 ENST00000367333.6
transmembrane protein 9
chr2_+_29113989 0.21 ENST00000404424.5
CAP-Gly domain containing linker protein family member 4
chr5_+_55853314 0.21 ENST00000354961.8
ENST00000297015.7
interleukin 31 receptor A
chr11_+_112176364 0.21 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr22_-_28711931 0.21 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr3_-_143848442 0.20 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr1_-_109393197 0.20 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr8_+_144147998 0.20 ENST00000326134.10
maestro heat like repeat family member 1
chr16_-_81220370 0.20 ENST00000337114.8
polycystin 1 like 2 (gene/pseudogene)
chr13_+_48037692 0.20 ENST00000258662.3
nudix hydrolase 15
chr1_+_15764419 0.19 ENST00000441801.6
filamin binding LIM protein 1
chr4_-_142846275 0.19 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
inositol polyphosphate-4-phosphatase type II B
chr22_+_21642287 0.19 ENST00000248958.5
stromal cell derived factor 2 like 1
chr2_+_113058637 0.18 ENST00000346807.7
interleukin 36 receptor antagonist
chr2_+_113059194 0.18 ENST00000393200.7
interleukin 36 receptor antagonist
chr7_-_111392915 0.18 ENST00000450877.5
inner mitochondrial membrane peptidase subunit 2
chr12_-_122500520 0.18 ENST00000540586.1
ENST00000543897.5
zinc finger CCHC-type containing 8
chr8_-_85341659 0.18 ENST00000522389.5
carbonic anhydrase 1
chr11_-_60183191 0.17 ENST00000412309.6
membrane spanning 4-domains A6A
chr2_+_90038848 0.17 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr17_-_64130813 0.17 ENST00000606895.2
endoplasmic reticulum to nucleus signaling 1
chr11_-_117877463 0.17 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr14_+_56117702 0.17 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chrX_+_41689006 0.17 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chrX_+_41688967 0.17 ENST00000378142.9
G protein-coupled receptor 34
chr8_-_48921419 0.17 ENST00000020945.4
snail family transcriptional repressor 2
chr11_+_2301987 0.17 ENST00000612299.4
ENST00000182290.9
tetraspanin 32
chr2_+_48314637 0.16 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chr18_-_46964408 0.16 ENST00000676383.1
elongin A3 family member D
chr15_-_101294905 0.16 ENST00000560496.5
small nuclear ribonucleoprotein polypeptide A'
chr3_-_185821092 0.16 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr1_+_167721954 0.15 ENST00000359523.7
ENST00000392121.7
ENST00000474859.5
myelin protein zero like 1
chr14_+_94174334 0.15 ENST00000328839.3
protein phosphatase 4 regulatory subunit 4
chr5_+_151259793 0.15 ENST00000523004.1
GM2 ganglioside activator
chr6_-_52840843 0.15 ENST00000370989.6
glutathione S-transferase alpha 5
chr2_+_233636502 0.15 ENST00000373445.1
UDP glucuronosyltransferase family 1 member A10
chr3_+_195720867 0.15 ENST00000436408.6
mucin 20, cell surface associated
chr11_-_129024157 0.15 ENST00000392657.7
Rho GTPase activating protein 32
chr17_-_50707855 0.14 ENST00000285243.7
ankyrin repeat domain 40
chr14_-_54441325 0.14 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
cornichon family AMPA receptor auxiliary protein 1
chr10_+_125896549 0.13 ENST00000368693.6
fibronectin type III and ankyrin repeat domains 1
chr5_+_62578810 0.13 ENST00000334994.6
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr1_-_92486916 0.13 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr13_+_45464901 0.13 ENST00000349995.10
component of oligomeric golgi complex 3
chr10_+_4963406 0.13 ENST00000380872.9
ENST00000442997.5
aldo-keto reductase family 1 member C1
chr1_+_207325629 0.12 ENST00000618707.2
CD55 molecule (Cromer blood group)
chr4_+_127632926 0.12 ENST00000335251.11
inturned planar cell polarity protein
chr19_+_54137740 0.12 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CCR4-NOT transcription complex subunit 3
chr19_+_10251901 0.12 ENST00000592514.5
ENST00000307422.9
ENST00000590150.5
ENST00000590669.5
mitochondrial ribosomal protein L4
chr12_-_23584600 0.12 ENST00000396007.6
SRY-box transcription factor 5
chr15_-_101295209 0.12 ENST00000254193.11
ENST00000626000.1
small nuclear ribonucleoprotein polypeptide A'
chr20_+_9514562 0.12 ENST00000246070.3
lysosomal associated membrane protein family member 5
chrX_-_6535118 0.12 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
variable charge X-linked 3A
chr2_+_200889411 0.12 ENST00000409357.5
ENST00000409129.2
NGG1 interacting factor 3 like 1
chr2_+_200889327 0.11 ENST00000426253.5
ENST00000454952.1
ENST00000651500.1
ENST00000409020.6
ENST00000359683.8
NGG1 interacting factor 3 like 1
chr22_-_28712136 0.11 ENST00000464581.6
checkpoint kinase 2
chr4_-_110641920 0.11 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr1_+_197268204 0.11 ENST00000535699.5
ENST00000538660.5
crumbs cell polarity complex component 1
chr1_-_207052980 0.11 ENST00000367084.1
YOD1 deubiquitinase
chr6_+_150368892 0.11 ENST00000229447.9
ENST00000392256.6
iodotyrosine deiodinase
chr12_+_16347102 0.11 ENST00000536371.5
ENST00000010404.6
microsomal glutathione S-transferase 1
chr12_+_56128217 0.10 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chr19_-_55166632 0.10 ENST00000532817.5
ENST00000527223.6
ENST00000391720.8
dynein axonemal assembly factor 3
chr7_-_113118544 0.10 ENST00000397764.8
ENST00000441359.1
small integral membrane protein 30
chr19_-_6737565 0.10 ENST00000601716.1
ENST00000264080.11
G protein-coupled receptor 108
chr5_+_132873660 0.10 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr16_-_68372258 0.10 ENST00000568373.5
ENST00000563226.1
sphingomyelin phosphodiesterase 3
chr11_-_95789474 0.10 ENST00000536839.1
family with sequence similarity 76 member B
chr19_-_55166671 0.10 ENST00000455045.5
dynein axonemal assembly factor 3
chr12_-_21910853 0.10 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr6_-_118935114 0.10 ENST00000316068.7
minichromosome maintenance 9 homologous recombination repair factor
chrX_+_15749848 0.10 ENST00000479740.5
ENST00000454127.2
carbonic anhydrase 5B
chr17_+_75261864 0.09 ENST00000245539.11
ENST00000579002.5
mitochondrial ribosomal protein S7
chr6_-_32128191 0.09 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
activating transcription factor 6 beta
chr22_-_29838227 0.09 ENST00000307790.8
ENST00000397771.6
ENST00000542393.5
activating signal cointegrator 1 complex subunit 2
chr11_-_95789744 0.09 ENST00000358780.10
ENST00000542135.5
family with sequence similarity 76 member B
chr3_+_186570663 0.09 ENST00000265028.8
DnaJ heat shock protein family (Hsp40) member B11
chr11_-_61161414 0.09 ENST00000301765.10
VPS37C subunit of ESCRT-I
chr11_+_118527463 0.09 ENST00000302783.10
tetratricopeptide repeat domain 36
chr19_+_10252206 0.09 ENST00000253099.11
ENST00000393733.6
ENST00000588502.5
mitochondrial ribosomal protein L4
chr16_+_50696999 0.09 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr19_-_55166565 0.09 ENST00000526003.5
ENST00000534170.5
ENST00000524407.7
dynein axonemal assembly factor 3
chr10_-_124418912 0.09 ENST00000368845.6
ENST00000539214.5
ornithine aminotransferase
chr12_+_28257195 0.09 ENST00000381259.5
coiled-coil domain containing 91
chr1_+_15617415 0.09 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr12_-_118359639 0.08 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr2_+_186506713 0.08 ENST00000445547.1
zinc finger CCCH-type containing 15
chr15_+_78438279 0.08 ENST00000560440.5
iron responsive element binding protein 2
chr15_+_58987652 0.08 ENST00000348370.9
ENST00000559160.1
ring finger protein 111
chr7_-_122699108 0.08 ENST00000340112.3
ring finger protein 133
chr5_+_111092172 0.08 ENST00000612402.4
WD repeat domain 36
chr2_+_196713117 0.08 ENST00000409270.5
coiled-coil domain containing 150
chrX_+_37349287 0.08 ENST00000466533.5
ENST00000542554.5
ENST00000543642.5
ENST00000484460.5
ENST00000378628.9
ENST00000449135.6
ENST00000463135.1
ENST00000465127.1
proline rich and Gla domain 1
novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein
chr4_+_37453914 0.08 ENST00000381980.9
ENST00000508175.5
chromosome 4 open reading frame 19
chr8_-_140800535 0.08 ENST00000521986.5
ENST00000523539.5
protein tyrosine kinase 2
chr4_+_25160631 0.08 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr8_+_49911604 0.08 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr19_-_17255448 0.07 ENST00000594059.1
novel protein
chr19_+_48445961 0.07 ENST00000253237.10
glutamate rich WD repeat containing 1
chr12_-_10826358 0.07 ENST00000240619.2
taste 2 receptor member 10
chrX_+_13689116 0.07 ENST00000464506.2
ENST00000243325.6
RAB9A, member RAS oncogene family
chr4_-_149815826 0.07 ENST00000636793.2
ENST00000636414.1
IQ motif containing M
chr19_-_14848922 0.07 ENST00000641129.1
olfactory receptor family 7 subfamily A member 10
chr8_-_673547 0.07 ENST00000522893.1
glutamate rich 1
chr3_+_319683 0.07 ENST00000620033.4
cell adhesion molecule L1 like
chr20_-_45972171 0.07 ENST00000322927.3
zinc finger protein 335
chr14_+_69398683 0.07 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
solute carrier family 39 member 9
chr8_+_49911396 0.07 ENST00000642720.2
syntrophin gamma 1
chr6_-_110179995 0.07 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr16_+_31873772 0.07 ENST00000394846.7
ENST00000300870.15
zinc finger protein 267
chr12_+_16347637 0.07 ENST00000543076.5
ENST00000396210.8
microsomal glutathione S-transferase 1
chr1_+_212432891 0.07 ENST00000366988.5
neudesin neurotrophic factor
chr20_+_59996335 0.07 ENST00000244049.7
ENST00000350849.10
ENST00000456106.1
cadherin 26
chr14_-_24242320 0.07 ENST00000557921.2
TERF1 interacting nuclear factor 2
chr12_-_52652207 0.06 ENST00000309680.4
keratin 2
chr21_-_14546297 0.06 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr10_-_133565542 0.06 ENST00000303903.10
ENST00000343131.7
synaptonemal complex central element protein 1
chr21_-_14210948 0.06 ENST00000681601.1
lipase I
chr12_-_14938508 0.06 ENST00000266397.7
endoplasmic reticulum protein 27
chr17_+_42458844 0.06 ENST00000393829.6
ENST00000537728.5
ENST00000343619.9
ENST00000264649.10
ENST00000585525.5
ENST00000544137.5
ENST00000589727.5
ENST00000587824.5
ATPase H+ transporting V0 subunit a1
chr13_-_46897021 0.06 ENST00000542664.4
ENST00000543956.5
5-hydroxytryptamine receptor 2A
chr3_+_122183664 0.06 ENST00000639785.2
calcium sensing receptor
chr11_-_13496018 0.05 ENST00000529816.1
parathyroid hormone
chr6_+_110180418 0.05 ENST00000368930.5
ENST00000307731.2
cell division cycle 40
chr16_+_6019016 0.05 ENST00000550418.6
RNA binding fox-1 homolog 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 0.7 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.2 2.2 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.6 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 0.5 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.3 GO:0043017 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.2 GO:0016108 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.1 0.8 GO:0045176 apical protein localization(GO:0045176)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 1.1 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.4 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 1.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 2.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.2 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:0060584 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.1 0.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.2 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 1.1 GO:0031143 pseudopodium(GO:0031143)
0.0 2.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 2.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 2.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 1.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.2 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway