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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXB8

Z-value: 0.86

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Transcription factors associated with HOXB8

Gene Symbol Gene ID Gene Info
ENSG00000120068.7 homeobox B8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB8hg38_v1_chr17_-_48614628_48614704-0.695.6e-02Click!

Activity profile of HOXB8 motif

Sorted Z-values of HOXB8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_26293025 1.69 ENST00000396376.5
sorting nexin 10
chr18_+_63887698 1.57 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr3_-_111595339 1.50 ENST00000317012.5
zinc finger BED-type containing 2
chr2_-_160200310 1.46 ENST00000620391.4
integrin subunit beta 6
chr2_-_160200251 1.46 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
integrin subunit beta 6
chr1_-_242449478 1.44 ENST00000427495.5
phospholipase D family member 5
chr2_-_160200289 1.40 ENST00000409872.1
integrin subunit beta 6
chr19_-_10587219 1.40 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
adaptor related protein complex 1 subunit mu 2
chr12_-_27971970 1.24 ENST00000395872.5
ENST00000201015.8
parathyroid hormone like hormone
chr1_+_101237009 1.23 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr12_-_27972725 1.19 ENST00000545234.6
parathyroid hormone like hormone
chr8_+_94641074 1.14 ENST00000423620.6
epithelial splicing regulatory protein 1
chr4_+_99816797 1.06 ENST00000512369.2
ENST00000296414.11
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr8_+_103880412 1.03 ENST00000436393.6
regulating synaptic membrane exocytosis 2
chr4_+_40197023 1.03 ENST00000381799.10
ras homolog family member H
chr3_+_189789643 1.01 ENST00000354600.10
tumor protein p63
chr10_+_46375645 0.98 ENST00000622769.4
annexin A8 like 1
chr10_+_46375619 0.98 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr3_+_189631373 0.96 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr1_+_24319342 0.94 ENST00000361548.9
grainyhead like transcription factor 3
chr4_+_76435216 0.93 ENST00000296043.7
shroom family member 3
chr7_+_70596078 0.92 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr4_-_122621011 0.89 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr4_-_71784046 0.88 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr5_+_140834230 0.85 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr5_+_140841183 0.85 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr22_+_44752552 0.82 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
Rho GTPase activating protein 8
chr5_+_140848360 0.81 ENST00000532602.2
protocadherin alpha 9
chr5_+_140882116 0.79 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chr5_+_140806929 0.74 ENST00000378125.4
ENST00000618834.1
ENST00000530339.2
ENST00000512229.6
ENST00000672575.1
protocadherin alpha 4
chr8_-_15238423 0.71 ENST00000382080.6
sarcoglycan zeta
chr11_+_18132565 0.68 ENST00000621697.2
MAS related GPR family member X3
chr12_+_8822610 0.67 ENST00000299698.12
alpha-2-macroglobulin like 1
chr2_-_70553638 0.67 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr17_-_3696033 0.66 ENST00000551178.5
ENST00000552276.5
ENST00000547178.5
purinergic receptor P2X 5
chr2_+_17539964 0.65 ENST00000457525.5
visinin like 1
chr2_-_70553440 0.64 ENST00000450929.5
transforming growth factor alpha
chr1_+_76867469 0.64 ENST00000477717.6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr12_-_95116967 0.62 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr1_+_24319511 0.61 ENST00000356046.6
grainyhead like transcription factor 3
chr6_+_130018565 0.60 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr11_+_118077009 0.59 ENST00000616579.4
ENST00000534111.5
transmembrane serine protease 4
chr8_-_90082871 0.58 ENST00000265431.7
calbindin 1
chr20_-_14337602 0.58 ENST00000378053.3
ENST00000341420.5
fibronectin leucine rich transmembrane protein 3
chr11_+_62856072 0.56 ENST00000377890.6
ENST00000681467.1
ENST00000538084.2
ENST00000681569.1
ENST00000377891.6
ENST00000680725.1
ENST00000377889.6
solute carrier family 3 member 2
chr3_-_112845950 0.56 ENST00000398214.5
CD200 receptor 1 like
chr12_+_20815672 0.55 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr10_+_24449426 0.54 ENST00000307544.10
KIAA1217
chr11_+_118077067 0.54 ENST00000522307.5
ENST00000523251.5
ENST00000437212.8
ENST00000522824.5
ENST00000522151.5
transmembrane serine protease 4
chr10_+_24466487 0.53 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr8_+_18391276 0.52 ENST00000286479.4
ENST00000520116.1
N-acetyltransferase 2
chr21_+_42199686 0.52 ENST00000398457.6
ATP binding cassette subfamily G member 1
chr19_+_45340760 0.52 ENST00000585434.5
kinesin light chain 3
chr20_-_1329131 0.52 ENST00000360779.4
syndecan binding protein 2
chr1_+_81800368 0.51 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr11_+_62856149 0.51 ENST00000535296.5
solute carrier family 3 member 2
chr16_-_28623560 0.51 ENST00000350842.8
sulfotransferase family 1A member 1
chr18_+_58196736 0.47 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr19_-_32869741 0.47 ENST00000590341.5
ENST00000587772.1
ENST00000023064.9
solute carrier family 7 member 9
chr6_+_116461364 0.47 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr16_+_57372481 0.45 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr1_+_186828941 0.45 ENST00000367466.4
phospholipase A2 group IVA
chr8_-_124565699 0.45 ENST00000519168.5
MTSS I-BAR domain containing 1
chr11_+_45921618 0.45 ENST00000529052.5
ENST00000531526.5
LARGE xylosyl- and glucuronyltransferase 2
chr19_+_48271327 0.44 ENST00000594024.5
ENST00000595408.5
ENST00000315849.5
zinc finger protein 114
chr3_+_189789734 0.44 ENST00000437221.5
ENST00000392463.6
ENST00000392461.7
ENST00000449992.5
ENST00000456148.1
tumor protein p63
chr7_+_107583919 0.44 ENST00000491150.5
B cell receptor associated protein 29
chr16_+_57372465 0.44 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr4_-_73620391 0.44 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr1_-_209784521 0.43 ENST00000294811.2
chromosome 1 open reading frame 74
chr15_-_72197772 0.43 ENST00000309731.12
GRAM domain containing 2A
chr14_-_67412112 0.42 ENST00000216446.9
pleckstrin 2
chr9_+_12693327 0.42 ENST00000388918.10
tyrosinase related protein 1
chr4_-_88158605 0.41 ENST00000237612.8
ATP binding cassette subfamily G member 2 (Junior blood group)
chr8_-_80171106 0.41 ENST00000519303.6
tumor protein D52
chr6_+_47698574 0.40 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr13_+_73054969 0.40 ENST00000539231.5
Kruppel like factor 5
chr6_+_47698538 0.39 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr14_-_23155302 0.39 ENST00000529705.6
solute carrier family 7 member 8
chr8_-_129786617 0.39 ENST00000276708.9
gasdermin C
chr8_+_97775775 0.39 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr13_-_103066411 0.38 ENST00000245312.5
solute carrier family 10 member 2
chr10_+_5446601 0.38 ENST00000449083.5
ENST00000380359.3
neuroepithelial cell transforming 1
chr8_+_97775829 0.37 ENST00000517924.5
lysosomal protein transmembrane 4 beta
chr19_-_14778552 0.37 ENST00000315576.8
adhesion G protein-coupled receptor E2
chr18_+_32018817 0.37 ENST00000217740.4
ENST00000583184.1
ring finger protein 125
novel transcript
chr1_-_247758680 0.36 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chr6_-_47042306 0.36 ENST00000371253.7
adhesion G protein-coupled receptor F1
chr12_-_39340963 0.35 ENST00000552961.5
kinesin family member 21A
chr10_+_46375721 0.34 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
novel transcript
annexin A8 like 1
chr21_-_26573211 0.34 ENST00000299340.9
ENST00000652641.2
cysteine and tyrosine rich 1
chr19_+_45340774 0.34 ENST00000589837.5
kinesin light chain 3
chr3_-_191282383 0.34 ENST00000427544.6
urotensin 2B
chr7_+_98106852 0.33 ENST00000297293.6
lemur tyrosine kinase 2
chr13_-_46182136 0.33 ENST00000323076.7
lymphocyte cytosolic protein 1
chr17_-_66229380 0.33 ENST00000205948.11
apolipoprotein H
chr8_+_127735597 0.32 ENST00000651626.1
MYC proto-oncogene, bHLH transcription factor
chr15_-_52295792 0.31 ENST00000261839.12
myosin VC
chr6_-_150025520 0.31 ENST00000367341.6
ENST00000286380.2
retinoic acid early transcript 1L
chr2_+_191276885 0.30 ENST00000392316.5
myosin IB
chr8_+_81280527 0.30 ENST00000297258.11
fatty acid binding protein 5
chr8_-_85378105 0.30 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
carbonic anhydrase 1
chr2_+_89884740 0.30 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr8_+_97887903 0.30 ENST00000520016.5
matrilin 2
chr7_+_20330893 0.30 ENST00000222573.5
integrin subunit beta 8
chr20_+_33217325 0.29 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chr14_+_22112280 0.29 ENST00000390454.2
T cell receptor alpha variable 25
chr4_+_143433491 0.29 ENST00000512843.1
GRB2 associated binding protein 1
chr17_-_41140487 0.29 ENST00000345847.4
keratin associated protein 4-6
chr3_-_197226351 0.29 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr19_+_7637099 0.29 ENST00000595950.5
ENST00000221283.10
ENST00000441779.6
ENST00000414284.6
syntaxin binding protein 2
chr5_+_151437040 0.29 ENST00000520111.5
ENST00000520701.5
ENST00000429484.6
solute carrier family 36 member 1
chr1_+_20589044 0.28 ENST00000375071.4
cytidine deaminase
chr5_+_122129533 0.28 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr19_-_42877988 0.28 ENST00000597058.1
pregnancy specific beta-1-glycoprotein 1
chr5_+_90474848 0.28 ENST00000651687.1
RNA polymerase III subunit G
chr9_+_128149447 0.28 ENST00000277480.7
ENST00000372998.1
lipocalin 2
chr19_-_9498596 0.28 ENST00000301480.5
zinc finger protein 560
chr11_+_27055215 0.28 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr16_+_50065959 0.28 ENST00000299192.8
HEAT repeat containing 3
chr6_+_106086316 0.28 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr15_-_51738095 0.28 ENST00000560491.2
LysM domain containing 2
chr12_+_20810698 0.27 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr1_+_86547070 0.27 ENST00000370563.3
chloride channel accessory 4
chr11_+_44095710 0.27 ENST00000358681.8
ENST00000343631.4
ENST00000682711.1
exostosin glycosyltransferase 2
chr5_+_90474879 0.27 ENST00000504930.5
ENST00000514483.5
RNA polymerase III subunit G
chr11_-_7796942 0.26 ENST00000329434.3
olfactory receptor family 5 subfamily P member 2
chr11_-_123654581 0.26 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr9_-_114806031 0.26 ENST00000374045.5
TNF superfamily member 15
chr7_-_45111673 0.26 ENST00000461363.1
ENST00000258770.8
ENST00000495078.1
ENST00000494076.5
ENST00000478532.5
ENST00000361278.7
transforming growth factor beta regulator 4
chr11_-_57427474 0.26 ENST00000533235.5
ENST00000526621.5
ENST00000352187.5
solute carrier family 43 member 3
chr1_-_200620729 0.26 ENST00000367350.5
kinesin family member 14
chr17_-_48430205 0.25 ENST00000336915.11
ENST00000584924.5
src kinase associated phosphoprotein 1
chr1_+_196774813 0.25 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr10_-_97401277 0.25 ENST00000315563.10
ENST00000370992.9
ENST00000414986.5
ribosomal RNA processing 12 homolog
chr4_-_73620629 0.25 ENST00000342081.7
Ras association domain family member 6
chr2_+_181985846 0.25 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
protein phosphatase 1 regulatory inhibitor subunit 1C
chr6_+_121435595 0.24 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr11_-_5324297 0.24 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr6_+_29301701 0.24 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr1_-_202808464 0.24 ENST00000648469.1
ENST00000648338.1
ENST00000367264.7
ENST00000648473.1
ENST00000648056.1
ENST00000650368.1
lysine demethylase 5B
chr4_+_69280472 0.23 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr2_-_99255107 0.23 ENST00000333017.6
ENST00000626374.2
ENST00000409679.5
ENST00000423306.1
lysozyme g2
chr2_-_142131004 0.23 ENST00000434794.1
ENST00000389484.8
LDL receptor related protein 1B
chr1_+_31413187 0.23 ENST00000373709.8
serine incorporator 2
chr7_+_120273129 0.23 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr3_-_190449782 0.23 ENST00000354905.3
transmembrane protein 207
chr1_-_216723437 0.23 ENST00000459955.5
ENST00000366937.5
ENST00000391890.7
estrogen related receptor gamma
chr15_-_51737611 0.23 ENST00000267838.7
LysM domain containing 2
chr10_+_125973373 0.23 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
fibronectin type III and ankyrin repeat domains 1
chr7_+_76461676 0.23 ENST00000425780.5
ENST00000456590.5
ENST00000451769.5
ENST00000324432.9
ENST00000457529.5
ENST00000446600.5
ENST00000430490.7
ENST00000413936.6
ENST00000423646.5
ENST00000438930.5
deltex E3 ubiquitin ligase 2
chr4_+_176319942 0.23 ENST00000503362.2
signal peptidase complex subunit 3
chr3_+_48223479 0.23 ENST00000652295.2
cathelicidin antimicrobial peptide
chr11_-_123654939 0.22 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr1_-_216723410 0.22 ENST00000469486.5
ENST00000481543.1
ENST00000408911.8
estrogen related receptor gamma
chr2_+_181986015 0.22 ENST00000409702.1
protein phosphatase 1 regulatory inhibitor subunit 1C
chr9_+_470291 0.22 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr9_-_41908681 0.22 ENST00000476961.5
contactin associated protein family member 3B
chr7_+_93906557 0.22 ENST00000248572.10
ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
G protein subunit gamma transducin 1
chr1_+_65992389 0.22 ENST00000423207.6
phosphodiesterase 4B
chr12_-_109021015 0.22 ENST00000546618.2
ENST00000610966.5
SV2 related protein
chr8_+_22059342 0.21 ENST00000415253.5
dematin actin binding protein
chr15_-_42273408 0.21 ENST00000389834.9
ENST00000307216.10
transmembrane protein 87A
chr11_-_129024157 0.21 ENST00000392657.7
Rho GTPase activating protein 32
chr15_-_21718245 0.21 ENST00000630556.1
novel gene identicle to IGHV1OR15-1
chr7_-_38265678 0.21 ENST00000443402.6
T cell receptor gamma constant 1
chr8_+_144477975 0.21 ENST00000435887.2
protein phosphatase 1 regulatory subunit 16A
chr9_-_39239174 0.21 ENST00000358144.6
contactin associated protein family member 3
chr2_-_24328113 0.21 ENST00000622089.4
intersectin 2
chr7_+_141776674 0.21 ENST00000247881.4
taste 2 receptor member 4
chr6_-_52087569 0.21 ENST00000340994.4
ENST00000371117.8
PKHD1 ciliary IPT domain containing fibrocystin/polyductin
chr21_+_36320183 0.21 ENST00000400485.6
MORC family CW-type zinc finger 3
chr12_-_14951106 0.20 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr5_-_79514127 0.20 ENST00000334082.11
homer scaffold protein 1
chr3_+_119579676 0.20 ENST00000357003.7
ADP-ribosylarginine hydrolase
chr6_-_53510445 0.20 ENST00000509541.5
glutamate-cysteine ligase catalytic subunit
chr11_+_66975271 0.20 ENST00000308963.4
chromosome 11 open reading frame 86
chr19_+_41797147 0.20 ENST00000596544.1
CEA cell adhesion molecule 3
chr12_-_21910853 0.20 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr2_+_195656734 0.20 ENST00000409086.7
solute carrier family 39 member 10
chr4_-_176195563 0.20 ENST00000280191.7
spermatogenesis associated 4
chr3_-_33645433 0.20 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr10_+_125896549 0.20 ENST00000368693.6
fibronectin type III and ankyrin repeat domains 1
chr12_+_112978386 0.20 ENST00000342315.8
2'-5'-oligoadenylate synthetase 2
chr8_+_86342539 0.20 ENST00000517970.6
WW domain containing E3 ubiquitin protein ligase 1
chr2_+_127645864 0.20 ENST00000544369.5
G protein-coupled receptor 17
chr11_-_57324907 0.20 ENST00000358252.8
tankyrase 1 binding protein 1
chr11_+_66975295 0.20 ENST00000683896.1
chromosome 11 open reading frame 86
chr5_+_55851349 0.19 ENST00000652347.2
interleukin 31 receptor A
chr1_+_99646025 0.19 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr17_-_76551174 0.19 ENST00000589145.1
cytoglobin
chr8_+_41529212 0.19 ENST00000520710.5
ENST00000518671.5
GINS complex subunit 4
chr2_+_89851723 0.19 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr12_+_101594849 0.19 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr2_-_86105839 0.19 ENST00000263857.11
RNA polymerase I subunit A
chr6_+_167111789 0.19 ENST00000400926.5
C-C motif chemokine receptor 6
chr12_-_118190510 0.19 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr12_+_124993633 0.19 ENST00000341446.9
ENST00000671775.2
BRI3 binding protein
chr17_-_40937641 0.19 ENST00000209718.8
keratin 23
chr17_-_43661915 0.19 ENST00000318579.9
ENST00000393661.2
mesenchyme homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.4 1.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4 4.4 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.3 0.9 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.2 1.1 GO:0060356 leucine import(GO:0060356)
0.2 0.5 GO:0009720 detection of hormone stimulus(GO:0009720)
0.1 1.0 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.9 GO:0098582 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.3 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.4 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 1.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.9 GO:0045176 apical protein localization(GO:0045176)
0.1 1.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.6 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.4 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.5 GO:0015811 L-cystine transport(GO:0015811)
0.1 2.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.4 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.2 GO:0007538 primary sex determination(GO:0007538)
0.1 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.9 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.6 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 1.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.0 0.7 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.0 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.0 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.0 0.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.0 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0060022 hard palate development(GO:0060022) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.7 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.7 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 1.7 GO:0045576 mast cell activation(GO:0045576)
0.0 0.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.0 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.7 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.0 GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.1 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.3 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 1.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.5 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.4 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.9 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:0000805 X chromosome(GO:0000805) autosome(GO:0030849)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 2.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1902271 D3 vitamins binding(GO:1902271)
0.2 2.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.5 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 0.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.2 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.3 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.3 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 2.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0035276 ethanol binding(GO:0035276)
0.0 0.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 4.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.2 GO:0086075 connexin binding(GO:0071253) gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0061598 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 2.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 4.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 2.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones