ISMARA results: HOXC11

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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXC11

Z-value: 0.35

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Transcription factors associated with HOXC11

Gene Symbol	Gene ID	Gene Info
HOXC11 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000123388.4	homeobox C11

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOXC11	hg38_v1_chr12_+_53973108_53973140	0.82	1.3e-02	Click!

Activity profile of HOXC11 motif

Sorted Z-values of HOXC11 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr20_+_59604527 Show fit	0.50	ENST00000371015.6	PHACTR3 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatase and actin regulator 3
chr8_+_103819244 Show fit	0.38	ENST00000262231.14 ENST00000507740.5 ENST00000408894.6	RIMS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	regulating synaptic membrane exocytosis 2
chr9_-_122227525 Show fit	0.24	ENST00000373755.6 ENST00000373754.6	LHX6 Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM homeobox 6
chr4_+_95051671 Show fit	0.23	ENST00000440890.7	BMPR1B Ensembl NCBI GeneCards UniProt NextProt Show fit	bone morphogenetic protein receptor type 1B
chr9_+_12693327 Show fit	0.23	ENST00000388918.10	TYRP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosinase related protein 1
chr12_-_52434363 Show fit	0.22	ENST00000252245.6	KRT75 Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 75
chr7_-_41703062 Show fit	0.22	ENST00000242208.5	INHBA Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibin subunit beta A
chr12_-_27971970 Show fit	0.22	ENST00000395872.5 ENST00000201015.8	PTHLH Ensembl NCBI GeneCards UniProt NextProt Show fit	parathyroid hormone like hormone
chr17_-_41489907 Show fit	0.22	ENST00000328119.11	KRT36 Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 36
chr6_-_136526472 Show fit	0.21	ENST00000454590.5 ENST00000432797.6	MAP7 Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule associated protein 7
chr1_+_160400543 Show fit	0.21	ENST00000368061.3	VANGL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	VANGL planar cell polarity protein 2
chr5_+_36606355 Show fit	0.21	ENST00000681909.1 ENST00000513903.5 ENST00000681795.1 ENST00000680125.1 ENST00000612708.5 ENST00000680232.1 ENST00000681776.1 ENST00000681926.1 ENST00000679958.1 ENST00000265113.9 ENST00000504121.5 ENST00000512374.1 ENST00000613445.5 ENST00000679983.1	SLC1A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 1 member 3
chrX_+_105948429 Show fit	0.19	ENST00000540278.1	NRK Ensembl NCBI GeneCards UniProt NextProt Show fit	Nik related kinase
chrX_-_134658450 Show fit	0.18	ENST00000359237.9	PLAC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	placenta enriched 1
chr16_+_57620077 Show fit	0.18	ENST00000567835.5 ENST00000569372.5 ENST00000563548.5 ENST00000562003.5	ADGRG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	adhesion G protein-coupled receptor G1
chr16_+_57619942 Show fit	0.18	ENST00000568908.5 ENST00000568909.5 ENST00000566778.5 ENST00000561988.5	ADGRG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	adhesion G protein-coupled receptor G1
chr5_-_83673544 Show fit	0.18	ENST00000503117.1 ENST00000510978.5	HAPLN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	hyaluronan and proteoglycan link protein 1
chr7_+_129144691 Show fit	0.17	ENST00000486685.3	TSPAN33 Ensembl NCBI GeneCards UniProt NextProt Show fit	tetraspanin 33
chr15_-_83283449 Show fit	0.16	ENST00000569704.2	BNC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	basonuclin 1
chr11_+_111245725 Show fit	0.16	ENST00000280325.7	C11orf53 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 11 open reading frame 53
chr2_-_51032151 Show fit	0.14	ENST00000628515.2	NRXN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 1
chr6_+_12290353 Show fit	0.14	ENST00000379375.6	EDN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	endothelin 1
chr12_-_95116967 Show fit	0.13	ENST00000551521.5	FGD6 Ensembl NCBI GeneCards UniProt NextProt Show fit	FYVE, RhoGEF and PH domain containing 6
chr4_+_143433491 Show fit	0.12	ENST00000512843.1	GAB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	GRB2 associated binding protein 1
chr15_-_43879835 Show fit	0.11	ENST00000636859.1	FRMD5 Ensembl NCBI GeneCards UniProt NextProt Show fit	FERM domain containing 5
chr18_-_55321986 Show fit	0.11	ENST00000570287.6	TCF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr9_-_122213874 Show fit	0.10	ENST00000482062.1	LHX6 Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM homeobox 6
chr21_-_30829755 Show fit	0.10	ENST00000621162.1	KRTAP7-1 Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin associated protein 7-1
chr2_+_27217361 Show fit	0.10	ENST00000264705.9 ENST00000403525.5	CAD Ensembl NCBI GeneCards UniProt NextProt Show fit	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr13_+_108596152 Show fit	0.10	ENST00000356711.7 ENST00000251041.10	MYO16 Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin XVI
chr17_-_43661915 Show fit	0.09	ENST00000318579.9 ENST00000393661.2	MEOX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	mesenchyme homeobox 1
chr9_-_122213903 Show fit	0.09	ENST00000464484.3	LHX6 Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM homeobox 6
chr4_-_25863537 Show fit	0.09	ENST00000502949.5 ENST00000264868.9 ENST00000513691.1 ENST00000514872.1	SEL1L3 Ensembl NCBI GeneCards UniProt NextProt Show fit	SEL1L family member 3
chr5_-_116536458 Show fit	0.09	ENST00000510263.5	SEMA6A Ensembl NCBI GeneCards UniProt NextProt Show fit	semaphorin 6A
chr4_+_113292925 Show fit	0.09	ENST00000673353.1 ENST00000505342.6 ENST00000672915.1 ENST00000509550.5	ANK2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin 2
chr6_+_15246054 Show fit	0.09	ENST00000341776.7	JARID2 Ensembl NCBI GeneCards UniProt NextProt Show fit	jumonji and AT-rich interaction domain containing 2
chr4_+_113292838 Show fit	0.09	ENST00000672411.1 ENST00000673231.1	ANK2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin 2
chr3_+_41194741 Show fit	0.08	ENST00000643541.1 ENST00000426215.5 ENST00000645210.1 ENST00000646381.1 ENST00000405570.6 ENST00000642248.1 ENST00000433400.6	CTNNB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	catenin beta 1
chr18_+_58196736 Show fit	0.08	ENST00000675221.1	NEDD4L Ensembl NCBI GeneCards UniProt NextProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr12_+_69825221 Show fit	0.08	ENST00000552032.7	MYRFL Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin regulatory factor like
chr6_+_157036315 Show fit	0.08	ENST00000637904.1	ARID1B Ensembl NCBI GeneCards UniProt NextProt Show fit	AT-rich interaction domain 1B
chr7_-_81770122 Show fit	0.07	ENST00000423064.7	HGF Ensembl NCBI GeneCards UniProt NextProt Show fit	hepatocyte growth factor
chr17_-_41528293 Show fit	0.07	ENST00000455635.1 ENST00000361566.7	KRT19 Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 19
chr4_-_173530219 Show fit	0.07	ENST00000359562.4	HAND2 Ensembl NCBI GeneCards UniProt NextProt Show fit	heart and neural crest derivatives expressed 2
chr3_+_63443306 Show fit	0.07	ENST00000472899.5 ENST00000479198.5 ENST00000460711.5 ENST00000465156.1	SYNPR Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptoporin
chr18_-_55351977 Show fit	0.07	ENST00000643689.1	TCF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr1_+_23019415 Show fit	0.07	ENST00000465864.2 ENST00000356634.7 ENST00000400181.9	KDM1A Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine demethylase 1A
chr8_-_94436926 Show fit	0.07	ENST00000481490.3	FSBP Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrinogen silencer binding protein
chr18_-_55322215 Show fit	0.07	ENST00000457482.7	TCF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr12_+_69825273 Show fit	0.07	ENST00000547771.6	MYRFL Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin regulatory factor like
chr19_+_4402615 Show fit	0.07	ENST00000301280.10	CHAF1A Ensembl NCBI GeneCards UniProt NextProt Show fit	chromatin assembly factor 1 subunit A
chrX_+_14529516 Show fit	0.06	ENST00000218075.9	GLRA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	glycine receptor alpha 2
chr11_+_63838902 Show fit	0.06	ENST00000377810.8	MARK2 Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule affinity regulating kinase 2
chr11_+_34642366 Show fit	0.06	ENST00000532302.1	EHF Ensembl NCBI GeneCards UniProt NextProt Show fit	ETS homologous factor
chr18_+_58255433 Show fit	0.06	ENST00000635997.1	NEDD4L Ensembl NCBI GeneCards UniProt NextProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr2_+_165572329 Show fit	0.06	ENST00000342316.8	CSRNP3 Ensembl NCBI GeneCards UniProt NextProt Show fit	cysteine and serine rich nuclear protein 3
chr4_-_84499281 Show fit	0.06	ENST00000295886.5	NKX6-1 Ensembl NCBI GeneCards UniProt NextProt Show fit	NK6 homeobox 1
chr4_-_48780242 Show fit	0.06	ENST00000507711.5 ENST00000358350.9	FRYL Ensembl NCBI GeneCards UniProt NextProt Show fit	FRY like transcription coactivator
chr14_-_56810448 Show fit	0.06	ENST00000339475.10 ENST00000555006.5 ENST00000672264.2 ENST00000554559.5 ENST00000555804.1	OTX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	orthodenticle homeobox 2
chr15_+_36594868 Show fit	0.06	ENST00000566807.5 ENST00000643612.1 ENST00000567389.5 ENST00000562877.5	CDIN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	CDAN1 interacting nuclease 1
chr8_-_108787563 Show fit	0.06	ENST00000297459.4	TMEM74 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 74
chr1_+_92168915 Show fit	0.06	ENST00000637221.2	BTBD8 Ensembl NCBI GeneCards UniProt NextProt Show fit	BTB domain containing 8
chr8_-_20183127 Show fit	0.05	ENST00000276373.10 ENST00000519026.5 ENST00000440926.3 ENST00000437980.3	SLC18A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 18 member A1
chr2_+_147845020 Show fit	0.05	ENST00000241416.12	ACVR2A Ensembl NCBI GeneCards UniProt NextProt Show fit	activin A receptor type 2A
chr7_-_27165517 Show fit	0.05	ENST00000396345.1 ENST00000343483.7	HOXA9 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox A9
chr8_-_20183090 Show fit	0.05	ENST00000265808.11 ENST00000522513.5	SLC18A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 18 member A1
chr18_+_58341038 Show fit	0.05	ENST00000679791.1	NEDD4L Ensembl NCBI GeneCards UniProt NextProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr8_+_106726115 Show fit	0.05	ENST00000521592.5	OXR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	oxidation resistance 1
chr19_+_49591170 Show fit	0.05	ENST00000418929.7	PRR12 Ensembl NCBI GeneCards UniProt NextProt Show fit	proline rich 12
chr20_+_34977625 Show fit	0.05	ENST00000618182.6	MYH7B Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin heavy chain 7B
chr8_+_106726012 Show fit	0.05	ENST00000449762.6 ENST00000297447.10	OXR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	oxidation resistance 1
chr1_-_93681829 Show fit	0.05	ENST00000260502.11	BCAR3 Ensembl NCBI GeneCards UniProt NextProt Show fit	BCAR3 adaptor protein, NSP family member
chr8_-_21812320 Show fit	0.05	ENST00000517328.5	GFRA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	GDNF family receptor alpha 2
chr11_+_34642468 Show fit	0.05	ENST00000527935.1	EHF Ensembl NCBI GeneCards UniProt NextProt Show fit	ETS homologous factor
chr14_-_56810380 Show fit	0.05	ENST00000672125.1 ENST00000673481.1	OTX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	orthodenticle homeobox 2
chr7_-_126533850 Show fit	0.05	ENST00000444921.3	GRM8 Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate metabotropic receptor 8
chr12_+_1691011 Show fit	0.05	ENST00000357103.5	ADIPOR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	adiponectin receptor 2
chr1_+_26159071 Show fit	0.05	ENST00000374268.5	FAM110D Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 110 member D
chr16_-_56425424 Show fit	0.05	ENST00000290649.10	AMFR Ensembl NCBI GeneCards UniProt NextProt Show fit	autocrine motility factor receptor
chr9_+_127264740 Show fit	0.05	ENST00000373387.9	GARNL3 Ensembl NCBI GeneCards UniProt NextProt Show fit	GTPase activating Rap/RanGAP domain like 3
chr20_+_44355692 Show fit	0.04	ENST00000316673.8 ENST00000609795.5 ENST00000457232.5 ENST00000609262.5	HNF4A Ensembl NCBI GeneCards UniProt NextProt Show fit	hepatocyte nuclear factor 4 alpha
chr8_+_26293112 Show fit	0.04	ENST00000523925.5 ENST00000315985.7	PPP2R2A Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2 regulatory subunit Balpha
chr3_-_79767987 Show fit	0.04	ENST00000464233.6	ROBO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	roundabout guidance receptor 1
chr4_+_71062642 Show fit	0.04	ENST00000649996.1	SLC4A4 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 4 member 4
chr1_+_110451132 Show fit	0.04	ENST00000271331.4	PROK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	prokineticin 1
chr3_-_45796518 Show fit	0.04	ENST00000413781.1 ENST00000358525.9	SLC6A20 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 6 member 20
chr14_+_55661272 Show fit	0.04	ENST00000555573.5	KTN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	kinectin 1
chr19_+_35545681 Show fit	0.04	ENST00000392205.2	TMEM147 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 147
chr5_-_83720813 Show fit	0.04	ENST00000515590.1 ENST00000274341.9	HAPLN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	hyaluronan and proteoglycan link protein 1
chr13_-_103066411 Show fit	0.04	ENST00000245312.5	SLC10A2 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 10 member 2
chrM_+_4467 Show fit	0.04	ENST00000361453.3	MT-ND2 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr6_+_156776020 Show fit	0.04	ENST00000346085.10	ARID1B Ensembl NCBI GeneCards UniProt NextProt Show fit	AT-rich interaction domain 1B
chr1_+_209704836 Show fit	0.04	ENST00000367027.5	HSD11B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid 11-beta dehydrogenase 1
chr12_-_70754631 Show fit	0.04	ENST00000440835.6 ENST00000549308.5 ENST00000550661.1 ENST00000378778.5	PTPRR Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase receptor type R
chr16_-_21652598 Show fit	0.04	ENST00000569602.1 ENST00000268389.6	IGSF6 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin superfamily member 6
chr8_+_76683779 Show fit	0.04	ENST00000523885.2	ZFHX4 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger homeobox 4
chr12_+_130162456 Show fit	0.03	ENST00000539839.1 ENST00000229030.5	FZD10 Ensembl NCBI GeneCards UniProt NextProt Show fit	frizzled class receptor 10
chr2_-_51032091 Show fit	0.03	ENST00000637511.1 ENST00000405472.7 ENST00000405581.3 ENST00000401669.7	NRXN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 1
chr17_+_81395449 Show fit	0.03	ENST00000675386.2	BAHCC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	BAH domain and coiled-coil containing 1
chrX_-_19799751 Show fit	0.03	ENST00000379698.8	SH3KBP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 domain containing kinase binding protein 1
chr3_-_45796467 Show fit	0.03	ENST00000353278.8 ENST00000456124.6	SLC6A20 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 6 member 20
chr17_+_7558258 Show fit	0.03	ENST00000483039.5 ENST00000380535.8 ENST00000396542.5	TNFSF13 Ensembl NCBI GeneCards UniProt NextProt Show fit	TNF superfamily member 13
chr13_-_46052712 Show fit	0.03	ENST00000242848.8 ENST00000679008.1 ENST00000282007.7	ZC3H13 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type containing 13
chr17_+_81395469 Show fit	0.03	ENST00000584436.7	BAHCC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	BAH domain and coiled-coil containing 1
chr18_-_55321640 Show fit	0.03	ENST00000637169.2	TCF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr21_+_37367097 Show fit	0.03	ENST00000644942.1	DYRK1A Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity tyrosine phosphorylation regulated kinase 1A
chr9_+_102995308 Show fit	0.03	ENST00000612124.4 ENST00000374798.8 ENST00000487798.5	CYLC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	cylicin 2
chr17_-_40665121 Show fit	0.03	ENST00000394052.5	KRT222 Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 222
chr1_+_167329044 Show fit	0.03	ENST00000367862.9	POU2F1 Ensembl NCBI GeneCards UniProt NextProt Show fit	POU class 2 homeobox 1
chr2_-_206159509 Show fit	0.03	ENST00000423725.5	NDUFS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH:ubiquinone oxidoreductase core subunit S1
chr6_+_151690492 Show fit	0.03	ENST00000404742.5 ENST00000440973.5	ESR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	estrogen receptor 1
chr3_+_101827982 Show fit	0.03	ENST00000461724.5 ENST00000483180.5 ENST00000394054.6	NFKBIZ Ensembl NCBI GeneCards UniProt NextProt Show fit	NFKB inhibitor zeta
chr7_-_11832190 Show fit	0.03	ENST00000423059.9 ENST00000617773.1	THSD7A Ensembl NCBI GeneCards UniProt NextProt Show fit	thrombospondin type 1 domain containing 7A
chr15_+_84981981 Show fit	0.03	ENST00000339708.9	PDE8A Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 8A
chr12_-_23949642 Show fit	0.03	ENST00000537393.5 ENST00000451604.7 ENST00000381381.6	SOX5 Ensembl NCBI GeneCards UniProt NextProt Show fit	SRY-box transcription factor 5
chr16_+_7303245 Show fit	0.03	ENST00000674626.1	RBFOX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding fox-1 homolog 1
chr22_+_39520553 Show fit	0.03	ENST00000674920.3 ENST00000679776.1 ENST00000675582.2 ENST00000337304.2 ENST00000676346.2 ENST00000396680.3 ENST00000680446.1 ENST00000674568.2 ENST00000680748.1 ENST00000674835.2	ATF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	activating transcription factor 4
chr1_+_209686173 Show fit	0.03	ENST00000615289.4 ENST00000367028.6 ENST00000261465.5	HSD11B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid 11-beta dehydrogenase 1
chr7_-_81770039 Show fit	0.02	ENST00000222390.11 ENST00000453411.6 ENST00000457544.7 ENST00000444829.7	HGF Ensembl NCBI GeneCards UniProt NextProt Show fit	hepatocyte growth factor
chr7_-_151519891 Show fit	0.02	ENST00000262187.10	RHEB Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras homolog, mTORC1 binding
chr12_+_11649666 Show fit	0.02	ENST00000396373.9	ETV6 Ensembl NCBI GeneCards UniProt NextProt Show fit	ETS variant transcription factor 6
chr19_+_35545575 Show fit	0.02	ENST00000222284.10 ENST00000392204.6	TMEM147 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 147
chr14_-_56805648 Show fit	0.02	ENST00000554788.5 ENST00000554845.1 ENST00000408990.8	OTX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	orthodenticle homeobox 2
chr17_+_59940908 Show fit	0.02	ENST00000591035.1	ENSG00000267318.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	novel protein
chr3_+_16265330 Show fit	0.02	ENST00000606098.1	OXNAD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	oxidoreductase NAD binding domain containing 1
chr15_-_53733103 Show fit	0.02	ENST00000559418.5	WDR72 Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 72
chr6_-_31777319 Show fit	0.02	ENST00000375688.5	VWA7 Ensembl NCBI GeneCards UniProt NextProt Show fit	von Willebrand factor A domain containing 7
chr21_+_37366744 Show fit	0.02	ENST00000647188.2	DYRK1A Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity tyrosine phosphorylation regulated kinase 1A
chr15_+_38454103 Show fit	0.02	ENST00000397609.6 ENST00000491535.5	FAM98B Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 98 member B
chr2_+_190649062 Show fit	0.02	ENST00000409581.5 ENST00000337386.10	NAB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	NGFI-A binding protein 1
chr2_-_40512361 Show fit	0.02	ENST00000403092.5	SLC8A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 8 member A1
chr11_+_31650024 Show fit	0.02	ENST00000638317.1	ELP4 Ensembl NCBI GeneCards UniProt NextProt Show fit	elongator acetyltransferase complex subunit 4
chr11_+_67586104 Show fit	0.02	ENST00000495996.1	GSTP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	glutathione S-transferase pi 1
chr21_+_37366894 Show fit	0.02	ENST00000647504.1	DYRK1A Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity tyrosine phosphorylation regulated kinase 1A
chr2_-_208146150 Show fit	0.02	ENST00000260988.5	CRYGB Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin gamma B
chr7_-_108569453 Show fit	0.02	ENST00000313516.5	THAP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	THAP domain containing 5
chr11_-_11353241 Show fit	0.02	ENST00000528848.3	CSNK2A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	casein kinase 2 alpha 3
chr8_-_18808837 Show fit	0.02	ENST00000286485.12	PSD3 Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin and Sec7 domain containing 3
chr10_+_113854610 Show fit	0.02	ENST00000369301.3	NHLRC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	NHL repeat containing 2
chr9_-_16705062 Show fit	0.02	ENST00000471301.3	BNC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	basonuclin 2
chr18_-_77017042 Show fit	0.02	ENST00000359645.7 ENST00000397875.7 ENST00000397869.7 ENST00000578193.5 ENST00000578873.5 ENST00000397866.8 ENST00000528160.1 ENST00000527041.1 ENST00000526111.5 ENST00000397865.9 ENST00000382582.7	MBP Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin basic protein
chr1_+_32362537 Show fit	0.02	ENST00000373534.4	TSSK3 Ensembl NCBI GeneCards UniProt NextProt Show fit	testis specific serine kinase 3
chr15_+_49423233 Show fit	0.01	ENST00000560270.1 ENST00000267843.9 ENST00000560979.1	FGF7 Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor 7
chr15_-_55249029 Show fit	0.01	ENST00000566877.5	RAB27A Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB27A, member RAS oncogene family
chr12_+_25052512 Show fit	0.01	ENST00000557489.5 ENST00000354454.7 ENST00000536173.5	IRAG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr1_-_17439657 Show fit	0.01	ENST00000375436.9	RCC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	regulator of chromosome condensation 2
chrX_-_10833643 Show fit	0.01	ENST00000380785.5 ENST00000380787.5	MID1 Ensembl NCBI GeneCards UniProt NextProt Show fit	midline 1
chr15_+_84981834 Show fit	0.01	ENST00000394553.6	PDE8A Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 8A
chr16_-_2264221 Show fit	0.01	ENST00000566397.5	RNPS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein with serine rich domain 1
chrX_+_66164340 Show fit	0.01	ENST00000441993.7 ENST00000419594.6 ENST00000425114.2	HEPH Ensembl NCBI GeneCards UniProt NextProt Show fit	hephaestin
chr3_+_173398438 Show fit	0.01	ENST00000457714.5	NLGN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neuroligin 1
chr2_+_127535746 Show fit	0.01	ENST00000428314.5 ENST00000409816.7	MYO7B Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin VIIB
chr1_-_241999091 Show fit	0.01	ENST00000357246.4	MAP1LC3C Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule associated protein 1 light chain 3 gamma
chr17_-_81918134 Show fit	0.01	ENST00000328666.11	SIRT7 Ensembl NCBI GeneCards UniProt NextProt Show fit	sirtuin 7
chr4_-_73223082 Show fit	0.01	ENST00000509867.6	ANKRD17 Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat domain 17
chr6_+_6588708 Show fit	0.01	ENST00000230568.5	LY86 Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte antigen 86
chr16_-_18896874 Show fit	0.01	ENST00000565324.5 ENST00000561947.5	SMG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr12_-_110920568 Show fit	0.01	ENST00000548438.1 ENST00000228841.15	MYL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin light chain 2
chr6_+_127577168 Show fit	0.01	ENST00000329722.8	C6orf58 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 6 open reading frame 58
chr8_+_133191060 Show fit	0.01	ENST00000519433.1 ENST00000517423.5 ENST00000220856.6	CCN4 Ensembl NCBI GeneCards UniProt NextProt Show fit	cellular communication network factor 4
chr2_-_40512423 Show fit	0.01	ENST00000402441.5 ENST00000448531.1	SLC8A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 8 member A1
chr18_+_3252208 Show fit	0.01	ENST00000578562.6	MYL12A Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin light chain 12A
chr7_-_20786879 Show fit	0.01	ENST00000418710.3 ENST00000617581.4 ENST00000361443.4	SP8 Ensembl NCBI GeneCards UniProt NextProt Show fit	Sp8 transcription factor
chr7_-_151520080 Show fit	0.01	ENST00000496004.5	RHEB Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras homolog, mTORC1 binding
chrX_+_66164210 Show fit	0.01	ENST00000343002.7 ENST00000336279.9	HEPH Ensembl NCBI GeneCards UniProt NextProt Show fit	hephaestin
chr8_-_113436883 Show fit	0.01	ENST00000455883.2 ENST00000297405.10	CSMD3 Ensembl NCBI GeneCards UniProt NextProt Show fit	CUB and Sushi multiple domains 3
chr12_-_52385649 Show fit	0.01	ENST00000257951.3	KRT84 Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 84
chr8_-_58500158 Show fit	0.01	ENST00000301645.4	CYP7A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome P450 family 7 subfamily A member 1
chr1_+_75134382 Show fit	0.01	ENST00000356261.4	LHX8 Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM homeobox 8
chr4_-_99144238 Show fit	0.01	ENST00000512499.5 ENST00000504125.1 ENST00000505590.5 ENST00000629236.2 ENST00000508393.5 ENST00000265512.12	ADH4 Ensembl NCBI GeneCards UniProt NextProt Show fit	alcohol dehydrogenase 4 (class II), pi polypeptide
chr7_-_27152561 Show fit	0.00	ENST00000467897.2 ENST00000612286.5 ENST00000498652.1	ENSG00000273433.1 Ensembl NCBI GeneCards UniProt NextProt Show fit HOXA3 Ensembl NCBI GeneCards UniProt NextProt Show fit ENSG00000272801.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	novel transcript homeobox A3 novel transcript
chr1_+_66533575 Show fit	0.00	ENST00000684751.1 ENST00000683291.1 ENST00000682054.1 ENST00000435165.3 ENST00000684539.1 ENST00000681971.1 ENST00000682476.1 ENST00000684168.1 ENST00000371039.5	SGIP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3GL interacting endocytic adaptor 1
chr1_-_120054225 Show fit	0.00	ENST00000602566.6	NOTCH2 Ensembl NCBI GeneCards UniProt NextProt Show fit	notch receptor 2
chr10_+_27532521 Show fit	0.00	ENST00000683924.1	RAB18 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB18, member RAS oncogene family
chr1_-_204166334 Show fit	0.00	ENST00000272190.9	REN Ensembl NCBI GeneCards UniProt NextProt Show fit	renin
chr2_-_165203870 Show fit	0.00	ENST00000639244.1 ENST00000409101.7 ENST00000668657.1	SCN3A Ensembl NCBI GeneCards UniProt NextProt Show fit	sodium voltage-gated channel alpha subunit 3
chr5_+_160229499 Show fit	0.00	ENST00000402432.4	FABP6 Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 6
chr5_-_36301883 Show fit	0.00	ENST00000502994.5 ENST00000515759.5 ENST00000296604.8	RANBP3L Ensembl NCBI GeneCards UniProt NextProt Show fit	RAN binding protein 3 like
chr6_-_49744378 Show fit	0.00	ENST00000371159.8 ENST00000263045.9	CRISP3 Ensembl NCBI GeneCards UniProt NextProt Show fit	cysteine rich secretory protein 3
chr9_+_92974476 Show fit	0.00	ENST00000337352.10	FGD3 Ensembl NCBI GeneCards UniProt NextProt Show fit	FYVE, RhoGEF and PH domain containing 3
chr12_+_25052634 Show fit	0.00	ENST00000548766.5	IRAG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr3_-_37174578 Show fit	0.00	ENST00000336686.9	LRRFIP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	LRR binding FLII interacting protein 2
chr7_+_114414809 Show fit	0.00	ENST00000350908.9	FOXP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	forkhead box P2

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC11

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.1	0.2	GO:0060279	positive regulation of ovulation(GO:0060279)
0.1	0.2	GO:0061341	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0	0.1	GO:0030185	nitric oxide transport(GO:0030185)
0.0	0.4	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.2	GO:0048165	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0	0.1	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.0	0.4	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.4	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.1	GO:0002071	glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) positive regulation of type B pancreatic cell development(GO:2000078)
0.0	0.2	GO:0009449	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.1	GO:0001757	somite specification(GO:0001757) sclerotome development(GO:0061056)
0.0	0.1	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0	0.2	GO:0036371	protein localization to T-tubule(GO:0036371)
0.0	0.2	GO:1900378	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.2	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0061032	cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.0	0.1	GO:0097026	dendritic cell dendrite assembly(GO:0097026)
0.0	0.1	GO:0061324	glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0	0.1	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
0.0	0.0	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.0	0.1	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1	0.2	GO:0060187	cell pole(GO:0060187)
0.0	0.1	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.0	0.4	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.2	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.3	GO:0034711	inhibin binding(GO:0034711)
0.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.0	GO:0055100	adiponectin binding(GO:0055100)
0.2	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.3	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.5	GO:0008157	protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR

Results for HOXC11

Z-value: 0.35

Motif logo

Transcription factors associated with HOXC11

Activity-expression correlation:

Activity profile of HOXC11 motif

Sorted Z-values of HOXC11 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC11

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: