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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXC12_HOXD12

Z-value: 0.80

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol Gene ID Gene Info
ENSG00000123407.4 homeobox C12
ENSG00000170178.7 homeobox D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD12hg38_v1_chr2_+_176099787_1760998120.753.2e-02Click!
HOXC12hg38_v1_chr12_+_53954870_539549120.019.9e-01Click!

Activity profile of HOXC12_HOXD12 motif

Sorted Z-values of HOXC12_HOXD12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91146195 1.78 ENST00000548218.1
decorin
chr4_-_155866277 1.42 ENST00000537611.3
acid sensing ion channel subunit family member 5
chr12_-_91179355 1.41 ENST00000550563.5
ENST00000546370.5
decorin
chr2_-_224947030 1.05 ENST00000409592.7
dedicator of cytokinesis 10
chr2_+_200585987 0.76 ENST00000374700.7
aldehyde oxidase 1
chr6_-_56851888 0.72 ENST00000312431.10
ENST00000520645.5
dystonin
chr9_-_70414657 0.70 ENST00000377126.4
Kruppel like factor 9
chr8_-_13276491 0.66 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr8_-_59119121 0.65 ENST00000361421.2
thymocyte selection associated high mobility group box
chr21_-_26843063 0.64 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843012 0.60 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr8_+_17027230 0.56 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr4_+_70028452 0.54 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
histatin 3
chr8_-_119592954 0.53 ENST00000522167.5
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr13_-_28718921 0.51 ENST00000266943.11
ENST00000380814.4
solute carrier family 46 member 3
chr1_+_113979391 0.49 ENST00000393300.6
ENST00000369551.5
olfactomedin like 3
chr1_+_113979460 0.49 ENST00000320334.5
olfactomedin like 3
chr3_-_195583931 0.48 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr5_+_169583636 0.48 ENST00000506574.5
ENST00000515224.5
ENST00000629457.2
ENST00000508247.5
ENST00000265295.9
ENST00000513941.5
spindle apparatus coiled-coil protein 1
chr9_-_86947496 0.46 ENST00000298743.9
growth arrest specific 1
chr7_+_90709816 0.44 ENST00000436577.3
cyclin dependent kinase 14
chr5_-_147453888 0.44 ENST00000398514.7
dihydropyrimidinase like 3
chr12_+_119667859 0.42 ENST00000541640.5
protein kinase AMP-activated non-catalytic subunit beta 1
chr6_+_101181254 0.41 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr3_+_148739798 0.41 ENST00000402260.2
angiotensin II receptor type 1
chr10_-_77638369 0.40 ENST00000372443.6
potassium calcium-activated channel subfamily M alpha 1
chr7_+_150368189 0.38 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr7_+_138460238 0.37 ENST00000343526.9
tripartite motif containing 24
chr19_-_45424364 0.37 ENST00000589165.5
ERCC excision repair 1, endonuclease non-catalytic subunit
chr1_+_35931076 0.35 ENST00000397828.3
ENST00000373191.9
argonaute RISC catalytic component 3
chr5_-_77087245 0.33 ENST00000255198.3
zinc finger BED-type containing 3
chr2_-_201698040 0.32 ENST00000396886.7
ENST00000409143.5
membrane palmitoylated protein 4
chr1_-_35718836 0.32 ENST00000270815.5
chromosome 1 open reading frame 216
chr9_+_2110354 0.31 ENST00000634772.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_77637902 0.30 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr10_-_77637721 0.30 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr5_-_88785493 0.29 ENST00000503554.4
myocyte enhancer factor 2C
chr10_-_77637789 0.29 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr19_-_21836164 0.29 ENST00000354959.9
ENST00000599906.5
zinc finger protein 43
chr6_-_166382927 0.28 ENST00000360961.11
mitochondrial pyruvate carrier 1
chr15_-_99249523 0.28 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
tetratricopeptide repeat domain 23
chr1_-_53220589 0.27 ENST00000294360.5
CXXC motif containing zinc binding protein
chr4_-_137532452 0.27 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr6_-_166382972 0.27 ENST00000341756.10
ENST00000621630.1
ENST00000621685.4
mitochondrial pyruvate carrier 1
chr12_+_104303726 0.27 ENST00000527879.2
EP300 interacting inhibitor of differentiation 3
chr7_-_13988863 0.27 ENST00000405358.8
ETS variant transcription factor 1
chr14_+_20891385 0.26 ENST00000304639.4
ribonuclease A family member 3
chr3_-_18424533 0.26 ENST00000417717.6
SATB homeobox 1
chr7_+_134646845 0.26 ENST00000344924.8
bisphosphoglycerate mutase
chr15_-_55588937 0.23 ENST00000302000.10
pygopus family PHD finger 1
chr16_-_12803785 0.23 ENST00000433677.6
ENST00000261660.4
ENST00000381774.9
calcineurin like phosphoesterase domain containing 1
chr13_-_51845169 0.23 ENST00000627246.3
ENST00000629372.3
transmembrane protein 272
chr10_-_37858037 0.23 ENST00000395873.7
ENST00000357328.8
ENST00000395874.2
zinc finger protein 248
chr8_-_13514744 0.21 ENST00000316609.9
DLC1 Rho GTPase activating protein
chr2_-_73233206 0.21 ENST00000258083.3
protease associated domain containing 1
chr10_+_122910605 0.20 ENST00000368894.2
family with sequence similarity 24 member A
chr7_-_27143672 0.20 ENST00000222726.4
homeobox A5
chr22_-_20320009 0.20 ENST00000405465.3
ENST00000248879.8
DiGeorge syndrome critical region gene 6 like
chr19_-_50837213 0.20 ENST00000326856.8
kallikrein related peptidase 15
chr6_-_169250825 0.20 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr6_+_31655888 0.19 ENST00000375916.4
apolipoprotein M
chr12_-_122395422 0.19 ENST00000540304.6
CAP-Gly domain containing linker protein 1
chr19_-_58440129 0.18 ENST00000254166.4
zinc finger protein 132
chr7_+_142770960 0.18 ENST00000632805.1
ENST00000633969.1
ENST00000539842.6
serine protease 2
chr4_+_153222402 0.18 ENST00000676335.1
ENST00000675146.1
tripartite motif containing 2
chr13_+_48976597 0.18 ENST00000541916.5
fibronectin type III domain containing 3A
chr4_-_113761068 0.17 ENST00000342666.9
ENST00000514328.5
ENST00000515496.5
ENST00000508738.5
ENST00000379773.6
calcium/calmodulin dependent protein kinase II delta
chr1_+_159005953 0.17 ENST00000426592.6
interferon gamma inducible protein 16
chr1_+_65264694 0.17 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr2_+_161136901 0.17 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr3_-_71360753 0.17 ENST00000648783.1
forkhead box P1
chr4_-_1208825 0.17 ENST00000511679.5
ENST00000617421.4
spondin 2
chr5_-_177006581 0.17 ENST00000506128.5
ubiquitin interaction motif containing 1
chr3_-_165078480 0.17 ENST00000264382.8
sucrase-isomaltase
chr1_+_149477960 0.17 ENST00000369227.7
NBPF member 19
chr9_+_135087652 0.16 ENST00000371793.8
ENST00000539529.5
ENST00000392991.8
olfactomedin 1
chr1_+_171090892 0.16 ENST00000367755.9
ENST00000479749.1
flavin containing dimethylaniline monoxygenase 3
chr12_-_52680398 0.16 ENST00000252244.3
keratin 1
chr19_-_48249841 0.16 ENST00000447740.6
caspase recruitment domain family member 8
chr7_+_142111739 0.16 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr8_-_92017637 0.16 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr4_-_82844418 0.15 ENST00000503937.5
SEC31 homolog A, COPII coat complex component
chr16_+_396713 0.15 ENST00000397722.5
NME/NM23 nucleoside diphosphate kinase 4
chr19_+_18557862 0.15 ENST00000222307.9
ENST00000601630.5
ENST00000599000.5
ENST00000595073.5
ENST00000596785.5
KxDL motif containing 1
chr6_-_104859828 0.15 ENST00000519645.5
ENST00000262903.9
ENST00000369125.6
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr11_-_77994641 0.15 ENST00000529807.5
ENST00000534064.6
ENST00000527522.1
integrator complex subunit 4
chr12_-_13095628 0.15 ENST00000457134.6
ENST00000537302.5
germ cell associated 1
chr5_-_181243370 0.15 ENST00000502844.5
receptor for activated C kinase 1
chr1_+_59310071 0.15 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr17_-_41481140 0.15 ENST00000246639.6
ENST00000393989.1
keratin 35
chr7_+_134646798 0.14 ENST00000418040.5
ENST00000393132.2
bisphosphoglycerate mutase
chr9_+_15553002 0.14 ENST00000380701.8
coiled-coil domain containing 171
chr8_-_42207667 0.14 ENST00000352041.7
ENST00000679151.1
ENST00000679300.1
plasminogen activator, tissue type
chr3_-_157533594 0.14 ENST00000487753.5
ENST00000489602.1
ENST00000461299.5
ENST00000479987.5
ventricular zone expressed PH domain containing 1
chr14_-_34713759 0.14 ENST00000673315.1
cofilin 2
chr9_-_21305313 0.14 ENST00000610521.2
interferon alpha 5
chr14_+_49598910 0.14 ENST00000298288.11
leucine rich repeat protein 1
chr8_-_27992624 0.13 ENST00000524352.5
scavenger receptor class A member 5
chr2_+_137964446 0.13 ENST00000280096.5
ENST00000280097.5
histamine N-methyltransferase
chr12_-_13095798 0.13 ENST00000396302.7
germ cell associated 1
chr16_+_20806698 0.13 ENST00000564274.5
ENST00000563068.1
RNA exonuclease 5
chr2_+_55519610 0.13 ENST00000406691.7
ENST00000407816.7
ENST00000349456.9
ENST00000403007.4
cilia and flagella associated protein 36
chr5_+_141387698 0.13 ENST00000615384.1
ENST00000519479.2
protocadherin gamma subfamily B, 4
chr1_+_248509536 0.13 ENST00000641501.1
olfactory receptor family 2 subfamily G member 6
chr1_-_220046432 0.13 ENST00000609181.5
ENST00000366923.8
glutamyl-prolyl-tRNA synthetase 1
chr16_+_397209 0.13 ENST00000382940.8
NME/NM23 nucleoside diphosphate kinase 4
chr12_-_71157872 0.12 ENST00000546561.2
tetraspanin 8
chr13_+_53028806 0.12 ENST00000219022.3
olfactomedin 4
chr19_+_18557762 0.12 ENST00000539106.5
ENST00000540691.5
KxDL motif containing 1
chrX_+_71366222 0.12 ENST00000683202.1
ENST00000373790.9
TATA-box binding protein associated factor 1
chr19_-_48255863 0.12 ENST00000522889.5
ENST00000519940.6
ENST00000520753.5
ENST00000519332.5
ENST00000521437.1
ENST00000520007.5
ENST00000651546.1
ENST00000521613.5
caspase recruitment domain family member 8
chr19_+_36851645 0.12 ENST00000331800.8
ENST00000612719.4
ENST00000586646.1
zinc finger protein 345
chr3_-_56468346 0.12 ENST00000288221.11
ELKS/RAB6-interacting/CAST family member 2
chr10_-_99913971 0.12 ENST00000543621.6
dynamin binding protein
chr17_+_47209375 0.12 ENST00000572303.1
myosin light chain 4
chr2_+_108378176 0.12 ENST00000409309.3
sulfotransferase family 1C member 4
chr6_+_32844789 0.12 ENST00000414474.5
proteasome 20S subunit beta 9
chr19_-_23687163 0.12 ENST00000601010.5
ENST00000601935.5
ENST00000600313.5
ENST00000596211.5
ENST00000359788.9
ENST00000599168.1
zinc finger protein 675
chr10_-_68527498 0.11 ENST00000609923.6
solute carrier family 25 member 16
chr11_-_67508091 0.11 ENST00000531506.1
cyclin dependent kinase 2 associated protein 2
chr12_-_30695852 0.11 ENST00000256079.9
importin 8
chr11_+_101914997 0.11 ENST00000263468.13
centrosomal protein 126
chr19_+_21142024 0.11 ENST00000600692.5
ENST00000599296.5
ENST00000594425.5
ENST00000311048.11
zinc finger protein 431
chr17_-_7329266 0.11 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr12_-_71157992 0.11 ENST00000247829.8
tetraspanin 8
chr4_+_99574812 0.11 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr9_-_94640130 0.11 ENST00000414122.1
fructose-bisphosphatase 1
chr12_-_95551417 0.11 ENST00000258499.8
ubiquitin specific peptidase 44
chr21_+_46286623 0.11 ENST00000397691.1
ybeY metalloendoribonuclease
chr22_+_22697789 0.11 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr8_-_42207557 0.11 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chr6_-_36547400 0.11 ENST00000229812.8
serine/threonine kinase 38
chr5_-_39270623 0.10 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr7_+_65373873 0.10 ENST00000450302.2
zinc finger protein 92
chr6_+_36871841 0.10 ENST00000359359.6
chromosome 6 open reading frame 89
chr10_-_27242068 0.10 ENST00000375901.5
ENST00000412279.1
ENST00000676731.1
ENST00000679220.1
ENST00000678392.1
ENST00000678446.1
ENST00000677441.1
ENST00000375905.8
acyl-CoA binding domain containing 5
chr19_+_20923275 0.10 ENST00000300540.7
ENST00000595854.5
ENST00000601284.5
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr14_+_73167829 0.10 ENST00000406768.1
presenilin 1
chr17_+_7549018 0.10 ENST00000293825.11
ENST00000293826.4
TNF superfamily member 12
TNFSF12-TNFSF13 readthrough
chr19_+_21082224 0.10 ENST00000620627.1
zinc finger protein 714
chr2_+_108377947 0.10 ENST00000272452.7
sulfotransferase family 1C member 4
chr2_+_169479445 0.10 ENST00000513963.1
ENST00000392663.6
ENST00000295240.8
novel protein
Bardet-Biedl syndrome 5
chr5_+_154941063 0.10 ENST00000523037.6
ENST00000265229.12
ENST00000439747.7
ENST00000522038.5
mitochondrial ribosomal protein L22
chr14_+_88005128 0.10 ENST00000267549.5
G protein-coupled receptor 65
chr14_-_34713788 0.10 ENST00000341223.8
cofilin 2
chr8_-_104467042 0.10 ENST00000521573.2
ENST00000351513.7
dihydropyrimidinase
chr7_+_65373839 0.10 ENST00000431504.1
ENST00000328747.12
zinc finger protein 92
chr19_-_18281612 0.10 ENST00000252818.5
JunD proto-oncogene, AP-1 transcription factor subunit
chr1_+_146959859 0.10 ENST00000617614.4
ENST00000439206.6
ENST00000617864.3
ENST00000613714.2
ENST00000579935.8
NBPF member 12
chr2_-_85418421 0.09 ENST00000409275.1
capping actin protein, gelsolin like
chr19_+_54816468 0.09 ENST00000391728.8
ENST00000326542.11
ENST00000358178.4
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
chr2_+_67397297 0.09 ENST00000644028.1
ENST00000272342.6
ETAA1 activator of ATR kinase
chr7_+_65373799 0.09 ENST00000357512.3
zinc finger protein 92
chr19_-_12551426 0.09 ENST00000416136.1
ENST00000339282.12
ENST00000596193.1
ENST00000428311.1
zinc finger protein 564
novel zinc finger protein
chr5_-_177006692 0.09 ENST00000507513.1
ENST00000511320.6
ubiquitin interaction motif containing 1
chr10_+_73110375 0.09 ENST00000617744.4
ENST00000544879.5
ENST00000537969.5
ENST00000357321.9
ENST00000349051.9
nudix hydrolase 13
chr6_-_111759053 0.09 ENST00000462856.6
ENST00000229471.8
FYN proto-oncogene, Src family tyrosine kinase
chr21_-_30487436 0.09 ENST00000334055.5
keratin associated protein 19-2
chr7_-_134459089 0.09 ENST00000285930.9
aldo-keto reductase family 1 member B
chr11_-_33717409 0.08 ENST00000651485.1
CD59 molecule (CD59 blood group)
chr2_-_200888993 0.08 ENST00000409264.6
ENST00000392283.9
peptidylprolyl isomerase like 3
chr6_-_89352706 0.08 ENST00000435041.3
ubiquitin conjugating enzyme E2 J1
chr8_+_12108172 0.08 ENST00000400078.3
zinc finger protein 705D
chr1_+_153658687 0.08 ENST00000368685.6
SNAP associated protein
chr7_+_80646305 0.08 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr4_-_689171 0.08 ENST00000512249.1
ENST00000515118.5
ENST00000347950.9
solute carrier family 49 member 3
chr2_-_70248598 0.08 ENST00000445587.5
ENST00000433529.7
ENST00000415783.6
TIA1 cytotoxic granule associated RNA binding protein
chr7_+_80646436 0.08 ENST00000419819.2
CD36 molecule
chr17_+_39699960 0.08 ENST00000445658.6
erb-b2 receptor tyrosine kinase 2
chr19_+_21082190 0.08 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
zinc finger protein 714
chr7_+_138460400 0.08 ENST00000415680.6
tripartite motif containing 24
chr7_+_148590760 0.08 ENST00000307003.3
chromosome 7 open reading frame 33
chr1_+_47023659 0.08 ENST00000371901.4
cytochrome P450 family 4 subfamily X member 1
chr2_-_210315160 0.08 ENST00000352451.4
myosin light chain 1
chr20_+_5950931 0.08 ENST00000265187.4
ENST00000652720.1
minichromosome maintenance 8 homologous recombination repair factor
novel protein
chr2_-_200889136 0.08 ENST00000409361.5
peptidylprolyl isomerase like 3
chr3_-_132684685 0.08 ENST00000512094.5
ENST00000632629.1
nephrocystin 3
NPHP3-ACAD11 readthrough (NMD candidate)
chr13_+_52455972 0.07 ENST00000490903.5
ENST00000480747.1
cytoskeleton associated protein 2
chr19_+_7680822 0.07 ENST00000596148.3
ENST00000317378.5
ENST00000426877.2
trafficking protein particle complex 5
chr15_+_78873723 0.07 ENST00000559690.5
ENST00000559158.5
mortality factor 4 like 1
chr6_-_49713521 0.07 ENST00000339139.5
cysteine rich secretory protein 2
chr16_+_16390834 0.07 ENST00000344087.4
nuclear pore complex interacting protein family member A7
chr11_-_26572130 0.07 ENST00000527569.1
mucin 15, cell surface associated
chr12_-_66130702 0.07 ENST00000446587.2
ENST00000266604.7
LLP homolog, long-term synaptic facilitation factor
chr9_-_92404559 0.07 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr6_-_131000722 0.07 ENST00000528282.5
erythrocyte membrane protein band 4.1 like 2
chr19_+_20923222 0.07 ENST00000597314.5
ENST00000328178.13
ENST00000601924.5
zinc finger protein 85
chr17_+_39700000 0.07 ENST00000584450.5
erb-b2 receptor tyrosine kinase 2
chr2_+_38875962 0.07 ENST00000340556.11
ENST00000410014.5
ENST00000644631.3
ENST00000409665.5
ENST00000409077.2
ENST00000409131.2
MORN repeat containing 2
chr2_-_200889266 0.07 ENST00000443398.5
ENST00000286175.12
ENST00000409449.5
peptidylprolyl isomerase like 3
chr19_+_37594830 0.07 ENST00000589117.5
zinc finger protein 540
chr19_-_19733091 0.07 ENST00000344099.4
zinc finger protein 14
chr8_-_77000070 0.07 ENST00000357039.9
peroxisomal biogenesis factor 2
chr3_+_10115667 0.07 ENST00000530758.2
BRICK1 subunit of SCAR/WAVE actin nucleating complex
chr13_-_52129051 0.07 ENST00000652119.1
ENST00000647945.1
ENST00000355568.8
NIMA related kinase 5
chr18_+_74499939 0.07 ENST00000584768.5
carnosine dipeptidase 2
chr17_-_38748184 0.07 ENST00000618941.4
ENST00000620225.5
ENST00000618506.1
ENST00000616129.4
polycomb group ring finger 2
chr22_+_22758698 0.07 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr17_+_68525795 0.07 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr17_-_41369807 0.07 ENST00000251646.8
keratin 33B

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 3.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 1.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.7 GO:0051414 response to cortisol(GO:0051414)
0.1 1.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.2 GO:0060435 bronchiole development(GO:0060435)
0.1 0.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.9 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.2 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.3 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0006212 uracil catabolic process(GO:0006212)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.3 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.3 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.0 0.1 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.6 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.3 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0007403 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 2.3 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.0 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.8 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 2.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0070404 NADH binding(GO:0070404)
0.0 0.0 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER