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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for IRF9

Z-value: 0.77

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Transcription factors associated with IRF9

Gene Symbol Gene ID Gene Info
IRF9
ENSG00000213928.9 interferon regulatory factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF9hg38_v1_chr14_+_24161257_241613220.695.8e-02Click!

Activity profile of IRF9 motif

Sorted Z-values of IRF9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_72212887 0.91 ENST00000523963.5
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_72212802 0.90 ENST00000401910.7
RIMS1
regulating synaptic membrane exocytosis 1
chr11_+_114060204 0.88 ENST00000683318.1
ZBTB16
zinc finger and BTB domain containing 16
chr17_+_6756035 0.72 ENST00000361842.8
ENST00000574907.5
XAF1
XIAP associated factor 1
chr17_+_6755834 0.67 ENST00000346752.8
XAF1
XIAP associated factor 1
chr13_-_42992165 0.64 ENST00000398762.7
ENST00000313640.11
ENST00000313624.12
EPSTI1
epithelial stromal interaction 1
chr5_+_32710630 0.64 ENST00000326958.5
NPR3
natriuretic peptide receptor 3
chr1_+_78649818 0.57 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr18_-_28036585 0.55 ENST00000399380.7
CDH2
cadherin 2
chr1_+_162632454 0.54 ENST00000367921.8
ENST00000367922.7
DDR2
discoidin domain receptor tyrosine kinase 2
chr6_-_81752671 0.45 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
TENT5A
terminal nucleotidyltransferase 5A
chr1_+_220879434 0.44 ENST00000366903.8
HLX
H2.0 like homeobox
chr3_-_122564232 0.41 ENST00000471785.5
ENST00000466126.1
PARP9
poly(ADP-ribose) polymerase family member 9
chr14_+_24161257 0.41 ENST00000396864.8
ENST00000557894.5
ENST00000559284.5
ENST00000560275.5
IRF9
interferon regulatory factor 9
chr3_-_122564577 0.39 ENST00000477522.6
ENST00000360356.6
PARP9
poly(ADP-ribose) polymerase family member 9
chr11_-_86672114 0.34 ENST00000393324.7
ME3
malic enzyme 3
chr11_-_86672630 0.33 ENST00000543262.5
ME3
malic enzyme 3
chr11_-_86672419 0.32 ENST00000524826.7
ENST00000532471.1
ME3
malic enzyme 3
chr11_-_57567617 0.31 ENST00000287156.9
UBE2L6
ubiquitin conjugating enzyme E2 L6
chr7_+_134866831 0.30 ENST00000435928.1
CALD1
caldesmon 1
chr2_-_151289613 0.28 ENST00000243346.10
NMI
N-myc and STAT interactor
chr15_+_91100194 0.28 ENST00000394232.6
SV2B
synaptic vesicle glycoprotein 2B
chr1_+_1013485 0.27 ENST00000649529.1
ISG15
ISG15 ubiquitin like modifier
chr9_-_92536031 0.27 ENST00000344604.9
ENST00000375540.5
ECM2
extracellular matrix protein 2
chr4_+_186069144 0.27 ENST00000513189.1
ENST00000296795.8
TLR3
toll like receptor 3
chr10_+_89332484 0.26 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
IFIT3
interferon induced protein with tetratricopeptide repeats 3
chr3_-_121660892 0.26 ENST00000428394.6
ENST00000314583.8
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_-_17405554 0.23 ENST00000252593.7
BST2
bone marrow stromal cell antigen 2
chr3_+_187368367 0.22 ENST00000259030.3
RTP4
receptor transporter protein 4
chrX_-_63785510 0.22 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9
chr4_+_159241016 0.21 ENST00000644902.1
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr6_-_24935942 0.20 ENST00000645100.1
ENST00000643898.2
ENST00000613507.4
RIPOR2
RHO family interacting cell polarization regulator 2
chr17_+_48831021 0.20 ENST00000509507.5
ENST00000448105.6
ENST00000570513.5
ENST00000509415.5
ENST00000513119.5
ENST00000416445.6
ENST00000508679.5
ENST00000258947.8
ENST00000505071.5
CALCOCO2
calcium binding and coiled-coil domain 2
chr10_+_89414555 0.20 ENST00000371795.5
ENST00000681422.1
IFIT5
interferon induced protein with tetratricopeptide repeats 5
chr7_+_101085464 0.19 ENST00000306085.11
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr17_+_80260826 0.19 ENST00000508628.6
ENST00000582970.5
ENST00000319921.4
RNF213
ring finger protein 213
chr1_+_241532121 0.18 ENST00000366558.7
KMO
kynurenine 3-monooxygenase
chr10_+_89301932 0.18 ENST00000371826.4
ENST00000679755.1
IFIT2
interferon induced protein with tetratricopeptide repeats 2
chr14_+_100065400 0.17 ENST00000555706.5
ENST00000392920.8
ENST00000555048.5
EVL
Enah/Vasp-like
chr9_-_21995301 0.16 ENST00000498628.6
CDKN2A
cyclin dependent kinase inhibitor 2A
chr16_-_15643024 0.16 ENST00000540441.6
MARF1
meiosis regulator and mRNA stability factor 1
chr3_-_179451387 0.15 ENST00000675901.1
ENST00000232564.8
ENST00000674862.1
ENST00000497513.1
GNB4
G protein subunit beta 4
chr11_-_615570 0.15 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
IRF7
interferon regulatory factor 7
chr4_-_76213724 0.15 ENST00000639738.1
SCARB2
scavenger receptor class B member 2
chr4_-_76213846 0.15 ENST00000639145.1
SCARB2
scavenger receptor class B member 2
chr3_-_146544538 0.13 ENST00000462666.5
PLSCR1
phospholipid scramblase 1
chr15_+_73994694 0.13 ENST00000268058.8
ENST00000395132.6
ENST00000268059.10
ENST00000354026.10
ENST00000565898.5
ENST00000569477.5
ENST00000569965.5
ENST00000567543.5
ENST00000436891.7
ENST00000435786.6
ENST00000564428.5
ENST00000359928.8
PML
PML nuclear body scaffold
chr3_-_146544850 0.13 ENST00000472349.1
PLSCR1
phospholipid scramblase 1
chr2_-_151261839 0.13 ENST00000331426.6
RBM43
RNA binding motif protein 43
chr9_-_21995262 0.13 ENST00000494262.5
CDKN2A
cyclin dependent kinase inhibitor 2A
chr17_-_4263847 0.13 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr4_-_76213817 0.12 ENST00000264896.8
ENST00000640640.1
ENST00000640957.1
SCARB2
scavenger receptor class B member 2
chr6_+_125919296 0.12 ENST00000444128.2
NCOA7
nuclear receptor coactivator 7
chr3_-_146544636 0.12 ENST00000486631.5
PLSCR1
phospholipid scramblase 1
chr6_+_3068487 0.12 ENST00000259808.9
RIPK1
receptor interacting serine/threonine kinase 1
chr4_-_76213589 0.12 ENST00000638603.1
ENST00000452464.6
SCARB2
scavenger receptor class B member 2
chr12_-_121039204 0.12 ENST00000620239.5
OASL
2'-5'-oligoadenylate synthetase like
chr14_+_22462932 0.12 ENST00000390477.2
TRDC
T cell receptor delta constant
chr12_-_56360084 0.12 ENST00000314128.9
ENST00000557235.5
ENST00000651915.1
STAT2
signal transducer and activator of transcription 2
chr3_-_146544701 0.12 ENST00000487389.5
PLSCR1
phospholipid scramblase 1
chr1_+_154405193 0.12 ENST00000622330.4
ENST00000344086.8
IL6R
interleukin 6 receptor
chr16_+_28863812 0.11 ENST00000684370.1
SH2B1
SH2B adaptor protein 1
chr6_+_125919210 0.11 ENST00000438495.6
NCOA7
nuclear receptor coactivator 7
chr12_-_121039236 0.11 ENST00000257570.9
OASL
2'-5'-oligoadenylate synthetase like
chr10_+_113679523 0.11 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
CASP7
caspase 7
chr20_-_49278034 0.11 ENST00000371744.5
ENST00000396105.6
ENST00000371752.5
ZNFX1
zinc finger NFX1-type containing 1
chr12_-_121039156 0.11 ENST00000339275.10
OASL
2'-5'-oligoadenylate synthetase like
chr10_+_113679839 0.11 ENST00000369318.8
ENST00000369315.5
CASP7
caspase 7
chr5_+_134526100 0.11 ENST00000395003.5
JADE2
jade family PHD finger 2
chr11_+_67023085 0.10 ENST00000527043.6
SYT12
synaptotagmin 12
chrX_-_49002197 0.10 ENST00000622231.1
ENST00000617369.4
ENST00000593475.5
ENST00000622599.4
GRIPAP1
GRIP1 associated protein 1
chr3_+_122680802 0.10 ENST00000474629.7
PARP14
poly(ADP-ribose) polymerase family member 14
chr19_+_17405685 0.10 ENST00000646744.1
ENST00000635536.2
ENST00000635060.2
ENST00000634291.2
ENST00000645298.1
ENST00000528911.5
BISPR
MVB12A
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chrX_-_49002256 0.10 ENST00000611705.4
ENST00000376423.8
GRIPAP1
GRIP1 associated protein 1
chr3_-_146544578 0.10 ENST00000342435.9
ENST00000448787.6
PLSCR1
phospholipid scramblase 1
chr3_-_122564253 0.10 ENST00000492382.5
ENST00000682323.1
ENST00000462315.5
PARP9
poly(ADP-ribose) polymerase family member 9
chr11_-_615921 0.09 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
IRF7
interferon regulatory factor 7
chr2_+_33476640 0.09 ENST00000425210.5
ENST00000444784.5
ENST00000423159.5
ENST00000403687.8
RASGRP3
RAS guanyl releasing protein 3
chr3_-_28348805 0.09 ENST00000457172.5
ENST00000479665.6
AZI2
5-azacytidine induced 2
chr1_-_182589239 0.08 ENST00000367559.7
ENST00000539397.1
RNASEL
ribonuclease L
chr1_+_236524581 0.08 ENST00000526634.5
LGALS8
galectin 8
chr6_-_117573571 0.08 ENST00000467125.1
ENSG00000282218.1
novel protein, GOPC-ROS1 readthrough
chr6_-_110415539 0.08 ENST00000368923.8
ENST00000368924.9
DDO
D-aspartate oxidase
chrX_-_40097403 0.08 ENST00000397354.7
BCOR
BCL6 corepressor
chr13_+_49495941 0.08 ENST00000378319.8
ENST00000496623.5
ENST00000426879.5
PHF11
PHD finger protein 11
chr3_-_71360753 0.07 ENST00000648783.1
FOXP1
forkhead box P1
chr13_+_49496355 0.07 ENST00000496612.5
ENST00000357596.7
ENST00000485919.5
ENST00000442195.5
PHF11
PHD finger protein 11
chr3_-_71581540 0.07 ENST00000650068.1
FOXP1
forkhead box P1
chr1_-_206946448 0.06 ENST00000356495.5
PIGR
polymeric immunoglobulin receptor
chr1_+_241532370 0.06 ENST00000366559.9
ENST00000366557.8
KMO
kynurenine 3-monooxygenase
chr12_+_6772512 0.06 ENST00000441671.6
ENST00000203629.3
LAG3
lymphocyte activating 3
chr12_-_121038967 0.06 ENST00000680620.1
ENST00000679655.1
ENST00000543677.2
OASL
2'-5'-oligoadenylate synthetase like
chr17_+_27631148 0.06 ENST00000313648.10
ENST00000395473.7
ENST00000577392.5
ENST00000584661.5
LGALS9
galectin 9
chr12_-_27014300 0.06 ENST00000535819.1
ENST00000543803.5
ENST00000535423.5
ENST00000539741.5
ENST00000343028.9
ENST00000545600.1
ENST00000543088.5
TM7SF3
transmembrane 7 superfamily member 3
chr1_-_161631032 0.06 ENST00000534776.1
ENST00000613418.4
ENST00000614870.4
FCGR3B
Fc fragment of IgG receptor IIIb
chr3_+_63911929 0.06 ENST00000487717.5
ATXN7
ataxin 7
chr19_+_17406099 0.05 ENST00000634942.2
ENST00000634568.1
ENST00000600514.5
BISPR
MVB12A
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr19_+_17405734 0.05 ENST00000635572.1
ENST00000634675.1
ENST00000634813.1
ENST00000647283.1
ENST00000635435.2
ENST00000634731.2
ENST00000635339.1
ENST00000528604.5
BISPR
MVB12A
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr3_+_63912588 0.05 ENST00000522345.2
ATXN7
ataxin 7
chr8_-_143986425 0.05 ENST00000313059.9
ENST00000524918.5
ENST00000313028.12
ENST00000525773.5
PARP10
poly(ADP-ribose) polymerase family member 10
chr9_+_99906646 0.05 ENST00000259400.11
ENST00000531035.5
ENST00000525640.5
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr20_+_62804794 0.05 ENST00000290291.10
OGFR
opioid growth factor receptor
chr9_-_33264559 0.04 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG1
BAG cochaperone 1
chr1_-_161631152 0.04 ENST00000421702.3
ENST00000650385.1
FCGR3B
Fc fragment of IgG receptor IIIb
chr3_-_28348924 0.04 ENST00000414162.5
ENST00000420543.6
AZI2
5-azacytidine induced 2
chr4_+_37891060 0.04 ENST00000261439.9
ENST00000508802.5
ENST00000402522.1
TBC1D1
TBC1 domain family member 1
chr22_+_18150162 0.04 ENST00000215794.8
USP18
ubiquitin specific peptidase 18
chr6_-_105137147 0.04 ENST00000314641.10
BVES
blood vessel epicardial substance
chr17_+_40140500 0.03 ENST00000264645.12
CASC3
CASC3 exon junction complex subunit
chr18_-_69956924 0.03 ENST00000581982.5
ENST00000280200.8
CD226
CD226 molecule
chr19_+_16143678 0.03 ENST00000613986.4
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr1_+_156082563 0.03 ENST00000368301.6
LMNA
lamin A/C
chr13_-_40982880 0.03 ENST00000635415.1
ELF1
E74 like ETS transcription factor 1
chr21_-_33931607 0.03 ENST00000429238.2
ENSG00000249209.2
novel protein similar to ATP synthase delta (OSCP) subunit domain
chr3_-_28348629 0.02 ENST00000334100.10
AZI2
5-azacytidine induced 2
chr20_+_11917859 0.02 ENST00000618296.4
ENST00000378226.7
BTBD3
BTB domain containing 3
chr3_-_142028617 0.02 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
TFDP2
transcription factor Dp-2
chr14_-_67515153 0.02 ENST00000555994.6
TMEM229B
transmembrane protein 229B
chr3_-_123980727 0.02 ENST00000620893.4
ROPN1
rhophilin associated tail protein 1
chr15_+_73994777 0.02 ENST00000563500.5
PML
PML nuclear body scaffold
chr4_+_87006988 0.01 ENST00000307808.10
AFF1
AF4/FMR2 family member 1
chr4_-_74794514 0.01 ENST00000395743.8
BTC
betacellulin
chr1_+_159009886 0.01 ENST00000340979.10
ENST00000368131.8
ENST00000295809.12
ENST00000368132.7
IFI16
interferon gamma inducible protein 16
chr6_-_33314247 0.01 ENST00000475304.5
ENST00000489157.5
TAPBP
TAP binding protein
chr6_-_33314202 0.01 ENST00000426633.6
ENST00000467025.1
TAPBP
TAP binding protein
chr17_-_42112674 0.01 ENST00000251642.8
ENST00000591220.5
DHX58
DExH-box helicase 58
chr4_-_76213520 0.00 ENST00000640634.1
SCARB2
scavenger receptor class B member 2
chr5_+_90640718 0.00 ENST00000640403.1
ADGRV1
adhesion G protein-coupled receptor V1
chr4_-_168318743 0.00 ENST00000393743.8
DDX60
DExD/H-box helicase 60
chr3_+_122564327 0.00 ENST00000296161.9
ENST00000383661.3
DTX3L
deltex E3 ubiquitin ligase 3L
chr18_+_3262956 0.00 ENST00000584539.1
MYL12B
myosin light chain 12B
chr9_+_68356603 0.00 ENST00000396396.6
PGM5
phosphoglucomutase 5
chr11_+_5624987 0.00 ENST00000429814.3
TRIM34
tripartite motif containing 34

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 1.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.3 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 1.8 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.5 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
0.1 0.2 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.3 GO:0045356 microglial cell activation involved in immune response(GO:0002282) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.3 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.6 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.3 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0 1.1 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.3 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions