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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for KLF1

Z-value: 2.04

Motif logo

Transcription factors associated with KLF1

Gene Symbol Gene ID Gene Info
ENSG00000105610.6 Kruppel like factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF1hg38_v1_chr19_-_12887188_128872070.541.7e-01Click!

Activity profile of KLF1 motif

Sorted Z-values of KLF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_43593054 6.14 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr15_+_43692886 5.36 ENST00000434505.5
ENST00000411750.5
creatine kinase, mitochondrial 1A
chr1_-_153616289 5.08 ENST00000368701.5
ENST00000344616.4
S100 calcium binding protein A14
chr19_-_35513641 3.94 ENST00000339686.8
ENST00000447113.6
dermokine
chr18_+_31447732 3.92 ENST00000257189.5
desmoglein 3
chr19_-_51020154 3.65 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr19_-_51020019 3.49 ENST00000309958.7
kallikrein related peptidase 10
chr11_+_130159773 3.39 ENST00000278742.6
ST14 transmembrane serine protease matriptase
chr19_-_51019699 3.37 ENST00000358789.8
kallikrein related peptidase 10
chr10_-_47484081 3.22 ENST00000583448.2
ENST00000583874.5
ENST00000585281.6
annexin A8
chr14_-_105168753 3.19 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr1_+_43933277 3.16 ENST00000414809.7
artemin
chrX_-_153886132 3.15 ENST00000370055.5
ENST00000370060.7
ENST00000420165.5
L1 cell adhesion molecule
chr10_+_46375619 3.11 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr1_+_43933794 3.09 ENST00000372359.10
ENST00000498139.6
ENST00000491846.5
artemin
chr10_-_47484133 3.08 ENST00000583911.5
ENST00000611843.4
annexin A8
chr18_+_23873000 3.00 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr16_-_31135699 2.97 ENST00000317508.11
ENST00000568261.5
ENST00000567797.1
serine protease 8
chr16_+_67199104 2.95 ENST00000360833.6
ENST00000652269.1
ENST00000393997.8
engulfment and cell motility 3
chr15_+_40252888 2.92 ENST00000559139.5
ENST00000560669.5
ENST00000542403.3
p21 (RAC1) activated kinase 6
chr6_+_150143018 2.77 ENST00000361131.5
protein phosphatase 1 regulatory inhibitor subunit 14C
chr17_-_41350824 2.74 ENST00000007735.4
keratin 33A
chr19_+_35115912 2.70 ENST00000603181.5
FXYD domain containing ion transport regulator 3
chr12_-_8662619 2.66 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr13_-_20232303 2.59 ENST00000400065.7
ENST00000643121.1
ENST00000647029.1
ENST00000643211.1
ENST00000400066.8
ENST00000644283.1
gap junction protein beta 6
chr12_-_8662703 2.58 ENST00000535336.5
microfibril associated protein 5
chr20_+_6767678 2.49 ENST00000378827.5
bone morphogenetic protein 2
chr14_-_23154422 2.24 ENST00000422941.6
solute carrier family 7 member 8
chr12_-_27970273 2.03 ENST00000542963.1
ENST00000535992.5
parathyroid hormone like hormone
chr2_+_17540670 2.02 ENST00000451533.5
ENST00000295156.9
visinin like 1
chr19_+_35116262 2.00 ENST00000604255.5
ENST00000344013.10
ENST00000346446.9
ENST00000603449.5
ENST00000605550.5
ENST00000604804.5
ENST00000605552.5
FXYD domain containing ion transport regulator 3
chr22_-_20268285 1.90 ENST00000043402.8
reticulon 4 receptor
chr12_+_56083308 1.85 ENST00000683164.1
ENST00000415288.6
ENST00000683018.1
erb-b2 receptor tyrosine kinase 3
chr17_-_35795592 1.84 ENST00000615136.4
ENST00000605424.6
ENST00000612672.1
matrix metallopeptidase 28
chr11_-_120138104 1.79 ENST00000341846.10
tripartite motif containing 29
chr1_+_14924100 1.79 ENST00000361144.9
kazrin, periplakin interacting protein
chr5_-_16617085 1.76 ENST00000684521.1
reticulophagy regulator 1
chr19_+_35115787 1.75 ENST00000604404.6
FXYD domain containing ion transport regulator 3
chr12_-_27970047 1.72 ENST00000395868.7
parathyroid hormone like hormone
chr1_-_116667668 1.72 ENST00000369486.8
ENST00000369483.5
immunoglobulin superfamily member 3
chr12_-_8662808 1.72 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chr19_+_35115872 1.69 ENST00000435734.6
FXYD domain containing ion transport regulator 3
chr3_-_129121761 1.67 ENST00000476465.5
ENST00000393304.5
ENST00000315150.10
ENST00000615093.1
ENST00000393308.5
ENST00000393307.5
ENST00000393305.5
RAB43, member RAS oncogene family
chr3_+_50155305 1.65 ENST00000002829.8
ENST00000426511.5
semaphorin 3F
chr6_+_7541612 1.63 ENST00000418664.2
desmoplakin
chr1_-_12616762 1.63 ENST00000464917.5
dehydrogenase/reductase 3
chr11_+_394196 1.59 ENST00000331563.7
ENST00000531857.1
plakophilin 3
chr5_-_16616972 1.58 ENST00000682564.1
ENST00000306320.10
ENST00000682229.1
reticulophagy regulator 1
chr2_+_172427573 1.55 ENST00000684293.1
ENST00000409080.6
ENST00000442250.6
integrin subunit alpha 6
chr6_+_7541662 1.53 ENST00000379802.8
desmoplakin
chr9_-_137054016 1.52 ENST00000312665.7
ENST00000355097.7
ectonucleoside triphosphate diphosphohydrolase 2
chr3_+_50155024 1.50 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr4_+_48016764 1.49 ENST00000295461.10
NIPA like domain containing 1
chr6_+_106098933 1.48 ENST00000369089.3
PR/SET domain 1
chr7_-_140062841 1.45 ENST00000263549.8
poly(ADP-ribose) polymerase family member 12
chr11_+_1839602 1.42 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr2_+_172427662 1.41 ENST00000264107.12
ENST00000458358.5
integrin subunit alpha 6
chr14_-_23154369 1.40 ENST00000453702.5
solute carrier family 7 member 8
chr2_+_181457342 1.39 ENST00000397033.7
ENST00000233573.6
integrin subunit alpha 4
chr10_+_80454274 1.37 ENST00000372158.6
ENST00000372157.6
ENST00000372164.7
ENST00000341863.10
tetraspanin 14
chr1_+_224616302 1.34 ENST00000272133.4
cornichon family AMPA receptor auxiliary protein 3
chr12_-_8662881 1.33 ENST00000433590.6
microfibril associated protein 5
chr17_-_7263181 1.32 ENST00000575313.1
ENST00000397317.8
claudin 7
chrX_-_153875847 1.27 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr17_-_41786688 1.23 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
junction plakoglobin
chr17_+_7439504 1.21 ENST00000575331.1
ENST00000293829.9
novel transcript
fibroblast growth factor 11
chr11_+_1840168 1.21 ENST00000381905.3
troponin I2, fast skeletal type
chr22_+_37906275 1.19 ENST00000215957.10
ENST00000445494.6
ENST00000680578.1
ENST00000424008.2
MICAL like 1
chr19_+_1077394 1.18 ENST00000590577.2
Rho GTPase activating protein 45
chr17_-_2711633 1.18 ENST00000435359.5
clustered mitochondria homolog
chr15_-_34367045 1.15 ENST00000617710.4
lysophosphatidylcholine acyltransferase 4
chr7_+_86644829 1.14 ENST00000439827.1
ENST00000421579.1
glutamate metabotropic receptor 3
chr17_-_41505597 1.10 ENST00000336861.7
ENST00000246635.8
ENST00000587544.5
ENST00000587435.1
keratin 13
chr6_-_138107412 1.10 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr2_+_96760857 1.05 ENST00000377075.3
cyclin and CBS domain divalent metal cation transport mediator 4
chr6_+_30882914 1.05 ENST00000509639.5
ENST00000412274.6
ENST00000507901.5
ENST00000507046.5
ENST00000437124.6
ENST00000454612.6
ENST00000396342.6
discoidin domain receptor tyrosine kinase 1
chr2_+_219442023 1.04 ENST00000431523.5
ENST00000396698.5
striated muscle enriched protein kinase
chr5_+_90474848 1.04 ENST00000651687.1
RNA polymerase III subunit G
chr19_+_41193198 1.03 ENST00000597754.1
ENST00000310054.9
cytochrome P450 family 2 subfamily S member 1
chr18_-_31162849 1.02 ENST00000257197.7
ENST00000257198.6
desmocollin 1
chr5_+_90474879 1.01 ENST00000504930.5
ENST00000514483.5
RNA polymerase III subunit G
chr6_+_41638438 0.99 ENST00000441667.5
ENST00000230321.11
ENST00000373050.8
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr16_+_56191476 0.98 ENST00000262493.12
G protein subunit alpha o1
chr17_+_32487686 0.96 ENST00000584792.5
cyclin dependent kinase 5 regulatory subunit 1
chr1_+_32741779 0.95 ENST00000401073.7
KIAA1522
chr17_-_48430205 0.93 ENST00000336915.11
ENST00000584924.5
src kinase associated phosphoprotein 1
chr4_-_25863537 0.93 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr6_+_33621313 0.92 ENST00000605930.3
inositol 1,4,5-trisphosphate receptor type 3
chr1_+_18107763 0.91 ENST00000251296.4
immunoglobin superfamily member 21
chr1_-_6466138 0.91 ENST00000356876.8
ENST00000377782.7
ENST00000351959.9
TNF receptor superfamily member 25
chr16_-_4416621 0.91 ENST00000570645.5
ENST00000574025.5
ENST00000572898.1
ENST00000537233.6
ENST00000571059.5
coronin 7
chr8_+_122781621 0.90 ENST00000314393.6
zinc fingers and homeoboxes 2
chr2_-_74440484 0.90 ENST00000305557.9
ENST00000233330.6
rhotekin
chr8_+_22054817 0.88 ENST00000432128.5
ENST00000443491.6
ENST00000517600.5
ENST00000523782.6
dematin actin binding protein
chr8_+_79611727 0.87 ENST00000518491.1
stathmin 2
chr3_+_142623386 0.85 ENST00000337777.7
ENST00000497199.5
plastin 1
chr9_-_33264678 0.82 ENST00000635077.1
ENST00000634734.3
BAG cochaperone 1
chr6_+_106086316 0.79 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr16_-_4416564 0.78 ENST00000572467.5
ENST00000251166.9
ENST00000572044.1
ENST00000571052.5
CORO7-PAM16 readthrough
coronin 7
chrX_-_153724343 0.78 ENST00000442093.5
ENST00000345046.12
ENST00000645377.1
ENST00000672675.1
ENST00000647529.1
ENST00000429550.5
B cell receptor associated protein 31
chr8_+_103500696 0.78 ENST00000666250.1
ENST00000668113.1
ENST00000504942.6
ENST00000632716.1
regulating synaptic membrane exocytosis 2
chr2_-_9003657 0.78 ENST00000462696.1
ENST00000305997.8
membrane bound O-acyltransferase domain containing 2
chr17_-_2711736 0.78 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr6_-_20212403 0.77 ENST00000324607.8
membrane bound O-acyltransferase domain containing 1
chr4_-_89835617 0.75 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr1_-_18956669 0.75 ENST00000455833.7
intermediate filament family orphan 2
chr17_-_40867200 0.75 ENST00000647902.1
ENST00000251643.5
keratin 12
chr1_+_55039511 0.75 ENST00000302118.5
proprotein convertase subtilisin/kexin type 9
chrX_-_31266925 0.74 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chr1_+_153775357 0.74 ENST00000624995.4
solute carrier family 27 member 3
chr2_-_219543793 0.74 ENST00000243776.11
chondroitin polymerizing factor
chr19_+_8053000 0.73 ENST00000390669.7
C-C motif chemokine ligand 25
chr5_-_116574395 0.73 ENST00000257414.12
semaphorin 6A
chr12_-_54384687 0.72 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
zinc finger protein 385A
chr1_-_26354080 0.71 ENST00000308182.10
crystallin beta-gamma domain containing 2
chr19_-_51027662 0.70 ENST00000594768.5
kallikrein related peptidase 11
chr19_+_8052315 0.70 ENST00000680646.1
C-C motif chemokine ligand 25
chr11_-_5227063 0.69 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr1_-_6466107 0.69 ENST00000348333.7
ENST00000351748.7
TNF receptor superfamily member 25
chr19_+_8052335 0.69 ENST00000680507.1
ENST00000680450.1
ENST00000681526.1
ENST00000680506.1
C-C motif chemokine ligand 25
chr19_-_43781249 0.69 ENST00000615047.4
potassium calcium-activated channel subfamily N member 4
chr1_-_10796636 0.68 ENST00000377022.8
ENST00000344008.5
castor zinc finger 1
chr2_-_38377256 0.67 ENST00000443098.5
ENST00000449130.5
ENST00000651368.1
ENST00000378954.9
ENST00000419554.6
ENST00000451483.1
ENST00000406122.5
atlastin GTPase 2
chr2_-_25982471 0.66 ENST00000264712.8
kinesin family member 3C
chr1_+_32765667 0.65 ENST00000373480.1
KIAA1522
chr6_+_142301926 0.65 ENST00000296932.13
ENST00000367609.8
adhesion G protein-coupled receptor G6
chr8_+_22053543 0.65 ENST00000519850.5
ENST00000381470.7
dematin actin binding protein
chr17_+_7307602 0.62 ENST00000573542.5
ENST00000336458.13
eukaryotic translation initiation factor 5A
chr10_+_69451456 0.62 ENST00000373290.7
tetraspanin 15
chr17_+_40015428 0.62 ENST00000394149.8
ENST00000225474.6
ENST00000331769.6
ENST00000394148.7
ENST00000577675.1
colony stimulating factor 3
chr12_+_56104527 0.62 ENST00000552766.5
ENST00000303305.11
proliferation-associated 2G4
chr17_+_7307579 0.61 ENST00000572815.5
eukaryotic translation initiation factor 5A
chr19_+_8052752 0.61 ENST00000315626.6
ENST00000253451.9
C-C motif chemokine ligand 25
chr9_-_34048868 0.61 ENST00000379239.9
ENST00000684158.1
ENST00000379238.7
ENST00000360802.6
ubiquitin associated protein 2
chr19_+_53867874 0.61 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
myeloid associated differentiation marker
chr17_-_45425620 0.60 ENST00000376922.6
Rho GTPase activating protein 27
chr12_-_123151029 0.60 ENST00000320201.10
phosphatidylinositol transfer protein membrane associated 2
chr17_+_7307531 0.57 ENST00000576930.5
eukaryotic translation initiation factor 5A
chr7_+_143284930 0.57 ENST00000409244.5
ENST00000409541.5
ENST00000410004.1
ENST00000359333.8
transmembrane protein 139
chr1_-_11805924 0.57 ENST00000418034.1
methylenetetrahydrofolate reductase
chr18_+_58045683 0.56 ENST00000592846.5
ENST00000675801.1
NEDD4 like E3 ubiquitin protein ligase
chr1_-_111200633 0.55 ENST00000357640.9
DENN domain containing 2D
chr9_-_98192614 0.54 ENST00000375077.5
coronin 2A
chr18_+_58045642 0.54 ENST00000676223.1
ENST00000675147.1
NEDD4 like E3 ubiquitin protein ligase
chr6_+_130018565 0.52 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr15_-_74433942 0.52 ENST00000543145.6
ENST00000261918.9
semaphorin 7A (John Milton Hagen blood group)
chr11_+_63888515 0.52 ENST00000509502.6
ENST00000512060.1
microtubule affinity regulating kinase 2
chr22_+_32043253 0.51 ENST00000266088.9
solute carrier family 5 member 1
chr3_+_49803212 0.50 ENST00000333323.6
inka box actin regulator 1
chr1_+_15764419 0.50 ENST00000441801.6
filamin binding LIM protein 1
chrX_+_48786578 0.49 ENST00000376670.9
GATA binding protein 1
chr17_-_29622893 0.49 ENST00000345068.9
ENST00000584602.1
ENST00000388767.8
ENST00000580212.6
coronin 6
chr5_+_81233314 0.48 ENST00000511719.5
ENST00000437669.5
ENST00000254035.9
ENST00000424301.6
ENST00000505060.1
creatine kinase, mitochondrial 2
chr2_+_241188509 0.48 ENST00000674324.1
ENST00000274979.12
anoctamin 7
chr14_+_24314700 0.48 ENST00000396782.2
leukotriene B4 receptor
chr17_-_41382298 0.48 ENST00000394001.3
keratin 34
chr16_+_46689640 0.48 ENST00000219097.7
ENST00000568364.6
origin recognition complex subunit 6
chr19_+_17747737 0.48 ENST00000600676.5
ENST00000600209.5
ENST00000596309.5
ENST00000598539.5
ENST00000597474.5
ENST00000593385.5
ENST00000598067.5
ENST00000593833.5
FCH and mu domain containing endocytic adaptor 1
chr22_+_31081310 0.46 ENST00000426927.5
ENST00000482444.5
ENST00000440425.5
ENST00000333137.12
ENST00000358743.5
ENST00000347557.6
smoothelin
chr1_+_26863140 0.46 ENST00000339276.6
stratifin
chr11_-_113475391 0.46 ENST00000362072.8
dopamine receptor D2
chr22_+_31082860 0.46 ENST00000619644.4
smoothelin
chr1_-_11805949 0.46 ENST00000376590.9
methylenetetrahydrofolate reductase
chr15_-_75712828 0.46 ENST00000308508.5
chondroitin sulfate proteoglycan 4
chr17_-_76027296 0.45 ENST00000301607.8
envoplakin
chr2_-_218286763 0.45 ENST00000444881.5
transmembrane BAX inhibitor motif containing 1
chrX_+_70452286 0.44 ENST00000374355.7
discs large MAGUK scaffold protein 3
chrX_+_48786562 0.44 ENST00000651144.1
ENST00000376665.4
GATA binding protein 1
chr2_+_62705644 0.44 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EH domain binding protein 1
chr20_-_4823597 0.44 ENST00000379400.8
Ras association domain family member 2
chr1_-_109397888 0.44 ENST00000256637.8
sortilin 1
chr1_-_11805977 0.44 ENST00000376486.3
methylenetetrahydrofolate reductase
chr5_-_116574802 0.44 ENST00000343348.11
semaphorin 6A
chr22_+_49853801 0.43 ENST00000216268.6
zinc finger BED-type containing 4
chr19_-_43780957 0.43 ENST00000648319.1
potassium calcium-activated channel subfamily N member 4
chr11_+_61481110 0.43 ENST00000338608.7
ENST00000432063.6
protein phosphatase 1 regulatory subunit 32
chr14_+_32934383 0.43 ENST00000551634.6
neuronal PAS domain protein 3
chr20_+_50731571 0.43 ENST00000371610.7
par-6 family cell polarity regulator beta
chr9_+_72149424 0.42 ENST00000358399.8
ENST00000376986.5
guanine deaminase
chrX_-_31266857 0.42 ENST00000378702.8
ENST00000361471.8
dystrophin
chr10_+_119207560 0.42 ENST00000392870.3
G protein-coupled receptor kinase 5
chr14_+_77181780 0.42 ENST00000298351.5
ENST00000554346.5
transmembrane protein 63C
chr14_-_22815421 0.42 ENST00000674313.1
ENST00000555959.1
solute carrier family 7 member 7
chr5_+_103258747 0.42 ENST00000319933.7
macrophage immunometabolism regulator
chr1_+_207321668 0.41 ENST00000367064.9
ENST00000314754.12
ENST00000367067.8
ENST00000644836.1
ENST00000343420.6
CD55 molecule (Cromer blood group)
chr14_-_21511290 0.41 ENST00000298717.9
methyltransferase like 3
chrX_+_69616067 0.41 ENST00000338901.4
ENST00000525810.5
ENST00000527388.5
ENST00000374553.6
ENST00000374552.9
ENST00000524573.5
ectodysplasin A
chr1_-_114670018 0.40 ENST00000393274.6
ENST00000393276.7
DENN domain containing 2C
chr19_-_48511793 0.40 ENST00000600059.6
lemur tyrosine kinase 3
chr19_+_42284020 0.39 ENST00000160740.7
capicua transcriptional repressor
chr13_+_23979794 0.39 ENST00000424834.6
ENST00000439928.2
spermatogenesis associated 13
spermatogenesis associated 13
chr1_+_207321532 0.39 ENST00000367063.6
ENST00000391921.9
ENST00000645323.1
CD55 molecule (Cromer blood group)
chr1_+_99646025 0.39 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr17_-_8087709 0.39 ENST00000647874.1
arachidonate 12-lipoxygenase, 12R type
chr17_-_29078857 0.38 ENST00000359450.6
TGFB1-induced anti-apoptotic factor 1
chr1_-_205775182 0.38 ENST00000446390.6
RAB29, member RAS oncogene family
chr2_-_61538516 0.38 ENST00000676771.1
ENST00000677814.1
ENST00000443240.5
ENST00000677556.1
ENST00000676553.1
exportin 1
chrX_-_3346641 0.38 ENST00000217939.7
matrix remodeling associated 5
chr3_+_8733779 0.37 ENST00000343849.3
ENST00000397368.2
caveolin 3
chr5_-_95961830 0.37 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
1.0 3.9 GO:1903575 cornified envelope assembly(GO:1903575)
1.0 3.9 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.8 3.4 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.8 2.5 GO:0060128 regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
0.8 2.3 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.7 2.8 GO:0002159 desmosome assembly(GO:0002159)
0.6 1.7 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.5 4.3 GO:0002934 desmosome organization(GO:0002934)
0.5 3.2 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.4 5.8 GO:0006600 creatine metabolic process(GO:0006600)
0.4 3.3 GO:0061709 reticulophagy(GO:0061709)
0.4 1.8 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 1.4 GO:0050904 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) diapedesis(GO:0050904)
0.3 1.0 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3 2.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 0.9 GO:0030221 basophil differentiation(GO:0030221)
0.3 1.5 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.3 0.3 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823)
0.3 3.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.3 2.0 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.7 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 1.5 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 6.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.7 GO:0030185 nitric oxide transport(GO:0030185)
0.2 0.7 GO:0006147 guanine catabolic process(GO:0006147)
0.2 1.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 0.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 0.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 5.1 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.2 0.8 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 0.6 GO:0071464 cellular response to hydrostatic pressure(GO:0071464)
0.2 1.4 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.2 0.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 0.9 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.2 0.7 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 7.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 0.3 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.2 0.5 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.2 0.5 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.2 0.9 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 1.0 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 1.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.5 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.8 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 2.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.8 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.5 GO:0043335 protein unfolding(GO:0043335)
0.1 0.4 GO:0008355 olfactory learning(GO:0008355)
0.1 1.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543)
0.1 3.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 1.9 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 15.0 GO:0070268 cornification(GO:0070268)
0.1 0.5 GO:0044467 glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1 1.7 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.3 GO:0002339 B cell selection(GO:0002339)
0.1 1.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:1902688 fermentation(GO:0006113) regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688)
0.1 3.0 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 3.6 GO:0015695 organic cation transport(GO:0015695)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 1.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.8 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.6 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.4 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 1.1 GO:0046541 saliva secretion(GO:0046541)
0.1 0.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 6.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 1.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.9 GO:0043622 cortical microtubule organization(GO:0043622)
0.1 0.5 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) regulation of rubidium ion transmembrane transporter activity(GO:2000686) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.2 GO:1904479 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1 1.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.2 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.5 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 4.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 2.5 GO:0051602 response to electrical stimulus(GO:0051602)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 2.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.0 2.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.7 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.0 2.0 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 1.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.4 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.9 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.2 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.3 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.2 GO:0097116 postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.8 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786) mesonephric duct morphogenesis(GO:0072180)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0005610 laminin-5 complex(GO:0005610)
0.4 14.3 GO:0030057 desmosome(GO:0030057)
0.3 1.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 0.7 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 5.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 5.5 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.7 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.2 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 3.0 GO:0005642 annulate lamellae(GO:0005642)
0.2 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.8 GO:1990357 terminal web(GO:1990357)
0.2 3.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.8 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 2.6 GO:0005861 troponin complex(GO:0005861)
0.1 2.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 2.6 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 1.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.2 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 2.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.4 GO:0005605 basal lamina(GO:0005605)
0.1 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 6.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0044307 dendritic branch(GO:0044307)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0000125 PCAF complex(GO:0000125)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 5.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.2 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.1 GO:0004111 creatine kinase activity(GO:0004111)
0.5 4.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5 2.7 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.4 4.8 GO:0038132 neuregulin binding(GO:0038132)
0.4 1.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.3 1.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3 1.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.3 3.6 GO:0019534 toxin transporter activity(GO:0019534)
0.2 1.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 0.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.7 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 2.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 2.5 GO:0070700 BMP receptor binding(GO:0070700)
0.2 2.6 GO:0031014 troponin T binding(GO:0031014)
0.2 0.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.7 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.2 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.4 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein antigen binding(GO:1990405)
0.2 1.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.2 0.5 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.2 1.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 3.9 GO:0038191 neuropilin binding(GO:0038191)
0.2 11.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 5.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 2.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 1.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 3.0 GO:0005112 Notch binding(GO:0005112)
0.1 5.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 2.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.7 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 2.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 1.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.6 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 0.3 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.1 1.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 1.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 3.6 GO:0042379 chemokine receptor binding(GO:0042379)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 12.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 7.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) primary miRNA binding(GO:0070878)
0.0 0.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 2.0 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 11.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 12.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 3.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.0 17.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.2 9.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 5.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 5.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 10.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.5 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 1.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids